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1. 发明授权

US09395869B2 Global z-order for windows 有权
标题翻译： Windows的全局z顺序
公开(公告)号：US09395869B2
公开(公告)日：2016-07-19
申请号：US13365159
申请日：2012-02-02
申请人： Philip James Holland
发明人： Philip James Holland
IPC分类号： G06F3/048 , G06F3/0481 , G06F9/44
CPC分类号： G06F3/04845 , G06F3/0481 , G06F9/451 , G06F2203/04803
摘要： In some implementations, windows can be displayed based on a global z-order. The global z-order can be maintained for all open windows. The global z-order can include windows that are not currently displayed. The global z-order can define a display order of windows across multiple workspaces. In some implementations, workspaces can be associated with respective levels. The workspace levels can be used to determine how to display windows associated with each workspace when multiple workspaces are displayed simultaneously.
摘要翻译：在一些实现中，可以基于全局z顺序显示窗口。可以为所有打开的窗口维护全局z顺序。全局z顺序可以包括当前未显示的窗口。全局z顺序可以在多个工作空间中定义窗口的显示顺序。在一些实现中，工作空间可以与相应的级别相关联。当同时显示多个工作空间时，工作空间级别可用于确定如何显示与每个工作空间相关联的窗口。

2. 发明授权

US08399420B2 Azacytidine analogues and uses thereof 失效
标题翻译：氮杂胞苷类似物及其用途
公开(公告)号：US08399420B2
公开(公告)日：2013-03-19
申请号：US12238054
申请日：2008-09-25
申请人： Lewis Silverman , James Holland , Marit Liland Sandvold , Finn Myhren , Ole Henrik Eriksen
发明人： Lewis Silverman , James Holland , Marit Liland Sandvold , Finn Myhren , Ole Henrik Eriksen
IPC分类号： A01N43/04 , A61K31/70
CPC分类号： C07D405/14 , A61K31/53 , A61K31/706 , C07H19/12
摘要： The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O); R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I); R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH; R4 is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O), provided that R and R4 are not simultaneously H; and R5 has the general formula: CH3—(CH2)n—(CH═CH—CH2)m—CH═CH—(CH2)k—; k is an integer from 0 to 7; m is an integer from 0 to 2; and n is an integer from 0 to 10, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed.
摘要翻译：本发明涉及如下式（I）化合物：其中R是H，R 5 C（O），R 5 CH 2 OC（O）或R 5 CH 2 NHC（O）; R1是交叉虚线表示连接R1与式（I）分子形成的键的位置。 R2和R3独立地是OH或H，条件是R2和R3不同时为OH; R4是H，R5C（O），R5CH2OC（O）或R5CH2NHC（O），条件是R和R4不同时为H; 并且R 5具有通式：CH 3 - （CH 2）n - （CH = CH-CH 2）m -CH = CH-（CH 2）k - ; k是0至7的整数; m为0〜2的整数; n为0〜10的整数，或其药学盐。还公开了制备和使用这些化合物的方法。

3. 发明申请

US20120175504A1 Electrical isolators 有权
标题翻译：电气隔离器
公开(公告)号：US20120175504A1
公开(公告)日：2012-07-12
申请号：US13498076
申请日：2010-09-23
申请人： William Michael James Holland , Jonathan Ephraim David Hurwitz , Iain Barnett
发明人： William Michael James Holland , Jonathan Ephraim David Hurwitz , Iain Barnett
IPC分类号： H03F3/08 , H01L31/16
CPC分类号： H04B10/802 , H03K17/78
摘要： The invention discloses an electrical isolator circuit comprising: an input stage comprising a transmitter of an opto-isolator; and an output stage comprising: a receiver of the opto-isolator; an active circuit in series with the receiver between the receiver and a power rail of the output stage; a first resistor connected to an output of the active circuit, and an input for the application of a predetermined voltage to the active circuit, the output stage being configured such that a varying output voltage is developed across the first resistor in response to input of a high voltage AC signal to the input stage. Ideally the output stage is operable to clamp the voltage across the receiver at the level of the predetermined voltage, thereby allowing for an increase in the load resistor and variable output resistor without increasing the time constant to unacceptably having regards to switching requirements.
摘要翻译：本发明公开了一种电气隔离器电路，包括：输入级，包括光隔离器的发射器; 以及输出级，包括：所述光隔离器的接收器; 与接收器和输出级的电源轨之间的接收器串联的有源电路; 连接到有源电路的输出的第一电阻器和用于向有源电路施加预定电压的输入端，所述输出级被配置为使得响应于输入端的输入，跨第一电阻器产生变化的输出电压高压交流信号到输入级。理想地，输出级可操作以在预定电压的水平上钳位接收器两端的电压，从而允许增加负载电阻器和可变输出电阻器，而不会在不考虑开关要求的情况下增加时间常数。

4. 发明授权

US08158605B2 Azacytidine analogues and uses thereof 有权
标题翻译：氮杂胞苷类似物及其用途
公开(公告)号：US08158605B2
公开(公告)日：2012-04-17
申请号：US12238125
申请日：2008-09-25
申请人： Lewis Silverman , James Holland
发明人： Lewis Silverman , James Holland
IPC分类号： A01N43/04 , A61K31/70
CPC分类号： C07D405/14 , A61K31/53 , A61K31/706 , C07H19/12
摘要： The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O); R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I); R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH; R4 is H or R5C(O), provided that R and R4 are not simultaneously H; and R5 is a C3-C26 alkenyl, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed.
摘要翻译：本发明涉及如下式（I）化合物：其中R为H，R 5 C（O）; R1是交叉虚线表示连接R1与式（I）分子形成的键的位置。 R2和R3独立地是OH或H，条件是R2和R3不同时为OH; R4是H或R5C（O），条件是R和R4不同时为H; R5为C3-C26烯基或其药物盐。还公开了制备和使用这些化合物的方法。

5. 发明授权

US07931808B2 Sequencing batch reactor with continuous membrane filtration and solids reduction 有权
标题翻译：连续膜过滤和固体还原的间歇式反应器
公开(公告)号：US07931808B2
公开(公告)日：2011-04-26
申请号：US12481486
申请日：2009-06-09
申请人： Robert A. Elefritz, Jr. , James Holland Scott, III
发明人： Robert A. Elefritz, Jr. , James Holland Scott, III
IPC分类号： C02F3/00
CPC分类号： C02F3/1221 , C02F3/1263 , C02F3/1268 , Y02W10/15
摘要： A method and system of treating wastewater that can provide operating flexibility is disclosed. The system is operated with a sequencing batch reactor, which is typically cycling to any of fill, react, settle, decant, and idle stages, to treat the wastewater. The system can further utilize a membrane filtration system to further treat water from the sequencing batch reactor and produce suitable water. A solids-reducing system can be connected to the sequencing batch reactor and reduce an amount of biodegraded solids by converting the character or distribution of microorganisms population in the biomass.
摘要翻译：公开了一种处理可提供操作灵活性的废水的方法和系统。该系统通过间歇式反应器进行操作，该反应器通常循环至任何填充，反应，沉降，倾析和空转阶段，以处理废水。该系统可以进一步利用膜过滤系统来进一步处理来自顺序间歇反应器的水并产生合适的水。可以将固体减少系统连接到顺序间歇反应器，并通过转化生物质中微生物群体的特征或分布来减少生物降解固体的量。

6. 发明申请

US20080112128A1 Cooling Methods and Apparatus 审中-公开
标题翻译：冷却方法与装置
公开(公告)号：US20080112128A1
公开(公告)日：2008-05-15
申请号：US11663493
申请日：2005-09-22
申请人： Michael James Holland
发明人： Michael James Holland
IPC分类号： H05K5/00 , F25B1/00
CPC分类号： H05K7/20818 , F24F1/01 , F24F2221/14 , F25B9/008 , F25B25/005 , F25B2309/06
摘要： Computer cooling equipment for computer equipment comprises: a primary heat transfer circuit; a secondary heat transfer circuit containing a secondary heat transfer fluid, a secondary condenser cooled by the primary heat transfer circuit and a secondary evaporator for cooling the computer equipment; and is characterised in that the secondary heat transfer fluid is a volatile fluid. The secondary heat transfer fluid may be carbon dioxide. The cooling system is of particular use in power hungry applications such as cooling of computer servers, particularly of blade servers as it can produce a heat load dissipation of up to 100 kW, compared to 10 kW or less using conventional systems. Heat exchange cabinets, air conditioning systems and building elements using a secondary heat transfer fluid which is a volatile fluid are also disclosed.
摘要翻译：计算机设备的计算机冷却设备包括：一次传热电路; 包含二次传热流体的二次传热回路，由一次传热回路冷却的二次冷凝器和用于冷却该计算机设备的二次蒸发器; 其特征在于，二次传热流体是挥发性流体。二次传热流体可以是二氧化碳。冷却系统在电力饥饿应用中特别有用，例如计算机服务器的冷却，特别是对于刀片服务器的冷却，因为它可以产生高达100kW的热负荷消耗，而与常规系统相比为10kW以下。还公开了使用作为挥发性流体的二次传热流体的热交换柜，空调系统和建筑元件。

7. 发明授权

US06040146A Detection of mammary tumor virus-like sequences in human breast cancer 失效
标题翻译：人乳腺癌乳腺肿瘤病毒样序列的检测
公开(公告)号：US06040146A
公开(公告)日：2000-03-21
申请号：US745892
申请日：1996-11-08
申请人： Beatriz Pogo , James Holland
发明人： Beatriz Pogo , James Holland
IPC分类号： G01N33/53 , C07H21/00 , C07H21/04 , C07K7/08 , C07K9/00 , C07K14/15 , C07K14/47 , C07K16/10 , C12N15/09 , C12Q1/68 , C12Q1/70 , G01N33/569 , G01N33/574 , C07K16/30
CPC分类号： C07K14/005 , C12Q1/6886 , G01N33/57415 , C12N2740/12022 , Y10S436/813
摘要： The present invention relates to materials and methods for diagnosing breast cancer in humans. It is based, at least in part, on the discovery that a substantial percentage of human breast cancer tissue samples contained nucleic acid sequences corresponding to a portion of the mouse mammary tumor virus env gene. In contrast, such sequences were absent in almost all other human tissues tested.
摘要翻译：本发明涉及用于诊断人类乳腺癌的材料和方法。至少部分地基于以下发现，即相当大部分的人乳腺癌组织样本含有对应于小鼠乳腺肿瘤病毒env基因的一部分的核酸序列。相比之下，几乎所有其他测试的人体组织中都没有这样的序列。

8. 发明授权

US2068680A Portable door latch 失效
标题翻译：便携式门锁
公开(公告)号：US2068680A
公开(公告)日：1937-01-26
申请号：US75922134
申请日：1934-12-26
申请人： JAMES HOLLAND
发明人： JAMES HOLLAND
IPC分类号： E05C19/18
CPC分类号： E05C19/182 , Y10T292/373 , Y10T292/379

9. 发明申请

US20220086466A1 ENHANCED REAL-TIME VISUAL QUALITY METRIC GENERATION FOR VIDEO CODING 有权
公开(公告)号：US20220086466A1
公开(公告)日：2022-03-17
申请号：US17457062
申请日：2021-12-01
申请人： James Holland , Muhammad Hamdan , Atthar Mohammed , Venkata Prasad , Dmitry Ryzhov
发明人： James Holland , Muhammad Hamdan , Atthar Mohammed , Venkata Prasad , Dmitry Ryzhov
IPC分类号： H04N19/196 , H04N19/172 , H04N19/176 , H04N19/159 , H04N19/146
摘要： This disclosure describes systems, methods, and devices related to generating visual quality metrics for encoded video frames. A method may include generating respective first visual quality metrics for pixels of an encoded video frame; generating respective second visual quality metrics for the pixels, the respective first visual quality metrics and the respective second visual quality metrics indicative of estimated human perceptions of the encoded video frame; generating a pixel block-based weight for the respective first visual quality metrics; generating a frame-based weight for the respective second visual quality metrics; and generating, based on the respective first visual quality metrics, the pixel block-based weight, the respective second visual quality metrics, and the frame-based weight, a human visual score indicative of a visual quality of the encoded video frame.

10. 发明授权

US08866113B2 Electrical isolator circuit 有权
标题翻译：隔离电路
公开(公告)号：US08866113B2
公开(公告)日：2014-10-21
申请号：US13498076
申请日：2010-09-23
申请人： William Michael James Holland , Jonathan Ephraim David Hurwitz , Iain Barnett
发明人： William Michael James Holland , Jonathan Ephraim David Hurwitz , Iain Barnett
IPC分类号： G02B27/00 , H04B10/80 , H03K17/78
CPC分类号： H04B10/802 , H03K17/78
摘要： The invention discloses an electrical isolator circuit comprising: an input stage comprising a transmitter of an opto-isolator; and an output stage comprising: a receiver of the opto-isolator; an active circuit in series with the receiver between the receiver and a power rail of the output stage; a first resistor connected to an output of the active circuit, and an input for the application of a predetermined voltage to the active circuit, the output stage being configured such that a varying output voltage is developed across the first resistor in response to input of a high voltage AC signal to the input stage. Ideally the output stage is operable to clamp the voltage across the receiver at the level of the predetermined voltage, thereby allowing for an increase in the load resistor and variable output resistor without increasing the time constant to unacceptably having regards to switching requirements.
摘要翻译：本发明公开了一种电气隔离器电路，包括：输入级，包括光隔离器的发射器; 以及输出级，包括：所述光隔离器的接收器; 与接收器和输出级的电源轨之间的接收器串联的有源电路; 连接到有源电路的输出的第一电阻器和用于向有源电路施加预定电压的输入端，所述输出级被配置为使得响应于输入端的输入，跨第一电阻器产生变化的输出电压高压交流信号到输入级。理想地，输出级可操作以在预定电压的水平上钳位接收器两端的电压，从而允许增加负载电阻器和可变输出电阻器，而不会在不考虑开关要求的情况下增加时间常数。

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