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1. 发明授权

US09492546B2 Use of bethanechol for treatment of Xerostomia 有权
标题翻译：使用bethanechol治疗口腔干燥症
公开(公告)号：US09492546B2
公开(公告)日：2016-11-15
申请号：US14115816
申请日：2012-05-04
申请人： Ian Walker , Michael Frodsham
发明人： Ian Walker , Michael Frodsham
IPC分类号： A61K31/27 , A61K47/22 , A61K31/37 , A61K9/00 , A61K9/08
CPC分类号： A61K47/22 , A61K9/006 , A61K9/08 , A61K31/27 , A61K31/37
摘要： A formulation for topical administration, comprises bethanechol and a penetration enhancer. The formulation is preferably used by being maintained in the buccal cavity for a period of time prior to being swallowed.
摘要翻译：用于局部给药的制剂包含甲酰胆碱和渗透促进剂。该制剂优选通过在吞咽之前保持在口腔中一段时间来使用。

2. 发明申请

US20130179231A1 INTELLIGENT MILESTONES FOR COLLABORATION SYSTEMS 审中-公开
标题翻译：用于协作系统的智能里程碑
公开(公告)号：US20130179231A1
公开(公告)日：2013-07-11
申请号：US13344471
申请日：2012-01-05
申请人： Akram Bou-Ghannam , William Denis Schwendner , Christan Theo Walenta , Ian Walker
发明人： Akram Bou-Ghannam , William Denis Schwendner , Christan Theo Walenta , Ian Walker
IPC分类号： G06Q10/06
CPC分类号： G06Q10/06 , G06Q10/10
摘要： A method for using an intelligent milestone for a collaboration system includes, with a physical computing system, determining event sources for a set of events associated with a milestone object for a project, subscribing the milestone object to the event sources, receiving event notifications from the event sources for the milestone object, and applying a set of predefined logical conditions using the event notifications to determine if an objective of the milestone object is complete.
摘要翻译：对于协作系统使用智能里程碑的方法包括与物理计算系统确定与项目的里程碑对象相关联的一组事件的事件源，将事件源的里程碑对象订阅，从事件源接收事件通知事件源，并使用事件通知应用一组预定义的逻辑条件，以确定里程碑对象的目标是否完整。

3. 发明申请

US20110015607A1 (BATMAN) DISPOSABLE ABSORBENT ARTICLE HAVING LEG WRAPS AND METHOD OF MAKING SAME 有权
标题翻译：（BATMAN）具有LEG WRAPS的可吸收吸收物品及其制造方法
公开(公告)号：US20110015607A1
公开(公告)日：2011-01-20
申请号：US12764874
申请日：2010-04-21
申请人： EDWARD KUO-SHU CHANG , Anne Smid , Patrick King Yu Tsang , Ian Walker , Andrew Wright
发明人： EDWARD KUO-SHU CHANG , Anne Smid , Patrick King Yu Tsang , Ian Walker , Andrew Wright
IPC分类号： A61F13/49 , B32B38/00
CPC分类号： A61F13/494 , A61F13/15593 , A61F13/49017 , A61F13/49406 , A61F13/49413 , A61F2013/49025 , A61F2013/49026 , A61F2013/49031 , A61F2013/49092 , Y10T156/1051
摘要： A leg wrap structure is provided in a disposable absorbent garment such as a diaper or training pants. The leg wrap structure has a base layer, a top layer, and an elastic construction disposed therebetween. The elastic construction includes a plurality of spaced apart (e.g. generally equally spaced apart) elastic elements (e.g. strands or threads) that are aligned in a generally in generally parallel relation. Further, the top and base layers define a region of inelasticity. The leg wrap structure provides for the efficient formation of a reservoir and a plurality of fluid dams each capable of capturing a quantity of fluid to minimize the occurrence of fluid leaks from the absorbent article. Methods of forming such absorbent articles are disclosed.
摘要翻译：腿部包裹结构设置在一次性吸收衣服中，例如尿布或训练裤。腿包裹结构具有底层，顶层以及设置在其间的弹性结构。弹性结构包括多个间隔开的（例如大体上等间隔开的）弹性元件（例如股线或螺纹），其以大致平行的关系排列。此外，顶层和底层限定非弹性区域。腿部包裹结构提供了有效地形成储存器和多个流体池，每个流体坝能够捕获一定量的流体以最小化来自吸收制品的流体泄漏的发生。公开了形成这种吸收制品的方法。

4. 发明申请

US20100000529A1 MANIFOLD FOR USE IN MEDICAMENT DISPENSER 有权
标题翻译：用于药物分配器的使用说明
公开(公告)号：US20100000529A1
公开(公告)日：2010-01-07
申请号：US11722193
申请日：2005-12-19
申请人： David Prime , Richard Ian Walker
发明人： David Prime , Richard Ian Walker
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0008 , A61M15/0041 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/0071 , A61M16/127 , A61M2202/064 , A61M2206/16
摘要： There is provided a manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack. The manifold comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit. The chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof in the airflow from the chamber inlet to said chamber outlet. The manifold is arranged such as to delay the emptying of the medicament powder from the blister pocket.
摘要翻译：提供了用于药物分配器装置中用于从泡罩包装的开放的泡罩口袋输送药物粉末的歧管。歧管包括主体，主体限定具有烟囱入口的烟囱和用于将烟气从烟囱入口引导到烟囱出口的烟囱出口; 所述主体还限定具有室入口和室出口的室。烟囱出口和所述室入口彼此并排地相互接合，使得当所述泡罩包装的所述开放泡罩袋定位在其附近时，所述气流可以经由开口泡罩口从烟囱出口引导到室入口以夹带所述药物粉末并且能够在从所述室入口到所述室出口的气流中进行输送。歧管布置成延迟药物粉末从泡罩袋中排空。

5. 发明申请

US20100000528A1 MANIFOLD FOR USE IN MEDICAMENT DISPENSER 审中-公开
标题翻译：用于药物分配器的使用说明
公开(公告)号：US20100000528A1
公开(公告)日：2010-01-07
申请号：US11722188
申请日：2005-12-19
申请人： Mark Gregory Palmer , Richard Ian Walker , Colin John Rouse
发明人： Mark Gregory Palmer , Richard Ian Walker , Colin John Rouse
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A61M15/0008 , A61M15/0041 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/0071 , A61M16/127 , A61M2202/064 , A61M2206/16
摘要： There is provided a manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack. The manifold comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from the chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit. The chimney exit and said chamber inlet lie side-by-side each other such that when said open blister pocket of said blister pack is positioned adjacent thereto said airflow may be directed from the chimney exit to the chamber inlet via the open blister pocket to entrain said medicament powder and enable transport thereof in the airflow from the chamber inlet to said chamber outlet. The chamber is arranged to promote break up of said entrained medicament powder by exposing the entrained medicament powder to one or more regions of differential force during its transport through the chamber.
摘要翻译：提供了用于药物分配器装置中用于从泡罩包装的开放的泡罩口袋输送药物粉末的歧管。歧管包括主体，主体限定具有烟囱入口的烟囱和用于将烟气从烟囱入口引导到烟囱出口的烟囱出口; 所述主体还限定具有室入口和室出口的室。烟囱出口和所述室入口彼此并排地相互接合，使得当所述泡罩包装的所述开放泡罩袋定位在其附近时，所述气流可以经由开口泡罩口从烟囱出口引导到室入口以夹带所述药物粉末并且能够在从所述室入口到所述室出口的气流中进行输送。所述腔室布置成通过在夹带的药物粉末通过腔室的运输期间将夹带的药物粉末暴露于一个或多个不同的力区域来促进所述夹带的药物粉末的分解。

6. 发明申请

US20080308102A1 Manifold for Use in Medicament Dispenser 有权
标题翻译：用于药液分配器的歧管
公开(公告)号：US20080308102A1
公开(公告)日：2008-12-18
申请号：US12096820
申请日：2006-12-11
申请人： Michael Birsha Davies , Mark Andrew Hailey , Mark Gregory Palmer , Richard Ian Walker
发明人： Michael Birsha Davies , Mark Andrew Hailey , Mark Gregory Palmer , Richard Ian Walker
IPC分类号： A61M15/00 , B65H5/28
CPC分类号： A61M15/0051 , A61M15/0003 , A61M15/0043 , A61M15/0045 , A61M15/0055 , A61M15/007 , A61M15/0075 , A61M15/0086 , A61M16/127 , A61M2202/064 , A61M2206/16
摘要： A manifold for use in a medicament dispenser device for the delivery of medicament powder from an open blister pocket of a blister pack comprises a body, the body defining a chimney having a chimney inlet and a chimney exit for directing airflow from said chimney inlet to the chimney exit; the body further defining a chamber having a chamber inlet and a chamber exit, wherein the chimney exit and the chamber inlet lie side-by-side each other such that when the open blister pocket of the blister pack is positioned adjacent thereto the airflow is directed from the chimney exit to the chamber inlet via the open blister pocket to entrain the medicament powder and enable transport thereof in the airflow from the chamber inlet to the chamber exit,and wherein one or more bleed holes are provided between the chimney and the chamber such that bleed airflow is able to be directed into the chamber to disruptively impact the airflow that transports the entrained medicament powder.
摘要翻译：一种用于药物分配器装置的歧管，用于从泡罩包装的开放的泡罩口袋输送药物粉末包括主体，主体限定具有烟囱入口的烟囱和用于将气流从所述烟囱入口引导到烟囱入口的烟囱出口烟囱出口所述主体还限定具有室入口和室出口的室，其中所述烟囱出口和所述室入口彼此并排放置，使得当所述泡罩包装的开口泡罩袋位于其旁边时，气流被定向从烟囱出口通过开放的泡罩袋从腔室入口夹带药剂粉末并使其能够在从腔室入口到腔室出口的气流中传输，并且其中在烟囱和腔室之间设置一个或多个排放孔，可以将排出的气流引导到室内以破坏地传递夹带的药物粉末的气流。

7. 外观设计

USD575476S1 Eyeball candy 有权
标题翻译：眼球糖果
公开(公告)号：USD575476S1
公开(公告)日：2008-08-26
申请号：US29286291
申请日：2007-04-30
申请人： Samy Hak-tang Lam , Ian Walker
设计人： Samy Hak-tang Lam , Ian Walker

8. 发明授权

US06972128B1 Use of human prostrate cell lines in prostate cancer treatment 有权
标题翻译：在前列腺癌治疗中使用人类前列腺细胞系
公开(公告)号：US06972128B1
公开(公告)日：2005-12-06
申请号：US09857691
申请日：1999-12-09
申请人： Angus George Dalgleish , Peter Michael Smith , Andrew Derek Sutton , Anthony Ian Walker
发明人： Angus George Dalgleish , Peter Michael Smith , Andrew Derek Sutton , Anthony Ian Walker
IPC分类号： A61K9/08 , A61K35/48 , A61K38/00 , A61K39/00 , A61K39/02 , A61K39/04 , A61K39/05 , A61K39/08 , A61K39/10 , A61K39/39 , A61K47/10 , A61K47/20 , A61K47/42 , A61P13/08 , A61P35/00 , A61P37/04 , A61K35/12
CPC分类号： A61K39/0011 , A61K2039/5152
摘要： The invention here relates to a product comprised of a cell line or lines intended for use as an allogeneic immunotherapy agent for the treatment of cancer in mammals and humans. All of the studies of cell-based cancer vaccines to date have one feature in common, namely the intention to use cells that contain at least some TSAs and/or TAAs that are shared with the antigens present in patients' tumour. In each case, tumour cells are utilised as the starting point on the premise that only tumour cells will contain TSAs or TAAs of relevance, and the tissue origins of the cells are matched to the tumour site in patients. A primary aspect of the invention is the use of immortalised normal, non-malignant cells as the basis of an allogeneic cell cancer vaccine. Normal cells do not possess TSAs or relevant concentrations of TAAs and hence it is surprising that normal cells are effective as anti-cancer vaccines. For prostate cancer, for example, a vaccine may be based on one or a combination of different immortalised normal cell lines derived from the prostate. The cell lines are lethally irradiated utilising gamma irradiation at 50–300 Gy to ensure that they are replication incompetent prior to use in the mammal or human.
摘要翻译：本发明涉及由用于治疗哺乳动物和人类癌症的同种异体免疫治疗剂的细胞系或细胞系的产品。迄今为止，基于细胞的癌症疫苗的所有研究具有共同的特征，即意图使用含有至少一些与存在于患者肿瘤中的抗原共享的TSA和/或TAA的细胞。在每种情况下，肿瘤细胞以起始点为前提，只有肿瘤细胞才含有相关的TSA或TAAs，并且细胞的组织起源与患者的肿瘤部位相匹配。本发明的主要方面是使用永生化的正常非恶性细胞作为同种异体细胞癌疫苗的基础。正常细胞不具有TSA或相关浓度的TAA，因此令人惊讶的是，正常细胞作为抗癌疫苗是有效的。对于前列腺癌，例如，疫苗可以基于来源于前列腺的不同永生化正常细胞系的一种或组合。使用50-300Gy的γ照射来致死细胞系，以确保它们在使用哺乳动物或人之前是无法复制的。

9. 发明授权

US06378519B1 Inhalation device 失效
公开(公告)号：US06378519B1
公开(公告)日：2002-04-30
申请号：US09456201
申请日：1999-12-07
申请人： Michael Birsha Davies , David John Hearne , Paul Kenneth Rand , Richard Ian Walker
发明人： Michael Birsha Davies , David John Hearne , Paul Kenneth Rand , Richard Ian Walker
IPC分类号： A61M1500
CPC分类号： A61M15/0045 , A61M15/0043 , A61M15/0051 , A61M15/0055 , A61M15/0068 , A61M15/0078 , A61M2206/16
摘要： An inhalation device is described for use with a medicament pack in which at least one container for medicament in powder form is defined between two sheets peelably secured to one another. The device comprises means for peeling the sheets apart at an opening station to open the container; and an outlet, communicating with the opened container, through which a user can inhale medicament in powder form from the opened container.

10. 发明授权

US6119853A Method and package for storing a pressurized container containing a drug 有权
公开(公告)号：US6119853A
公开(公告)日：2000-09-19
申请号：US216183
申请日：1998-12-18
申请人： Karl Andrew Garrill , Richard J. Haan , Craig Steven Herman , Richard Ian Walker
发明人： Karl Andrew Garrill , Richard J. Haan , Craig Steven Herman , Richard Ian Walker
IPC分类号： B65D83/38 , A61J1/14 , A61J3/00 , A61M11/00 , A61M15/00 , A61M16/20 , B65D65/40 , B65D75/20 , B65D75/26 , B65D75/54 , B65D77/04 , B65D81/24 , B65D81/26 , B65D83/00 , B65D83/14 , B65D30/02
CPC分类号： B65D83/75 , A61M15/009 , B65D75/26 , B65D81/268 , A61M2202/062 , A61M2209/06
摘要： A method and package for storing a pressurized container which is filled with a drug formulation at a predetermined pressure. The drug formulation includes a mixture of a drug and a propellant. The package which encloses the pressurized container substantially prevents ingression of water vapor and particulate matter into the package while permitting egression of the propellant which may leak from the pressurized container.

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