专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US11684096B2 Horizontally flat-foldable mask having five surfaces 有权
公开(公告)号：US11684096B2
公开(公告)日：2023-06-27
申请号：US16771889
申请日：2019-10-23
申请人： In Jong Kim
发明人： Sang Ho Lee
IPC分类号： A41D13/11
CPC分类号： A41D13/1115
摘要： A horizontally flat-foldable mask includes a main body having, in a folded state, a middle lobe, an upper lobe, a lower lobe, a first fold section extending upward from the middle lobe, horizontally folded from the upper lobe and having a first mid seam line curved or inclined downward from center toward both sides, and a second fold section extending downward from the middle lobe, horizontally folded from the lower lobe and having a second mid seam line curved or inclined upward from center toward both sides, and harnesses fixed to both sides of the main body.

2. 发明申请

US20130078217A1 2'-CHLOROACETYLENYL SUBSTITUTED NUCLEOSIDE DERIVATIVES 有权
标题翻译： 2'-氯乙酰基取代的核苷衍生物
公开(公告)号：US20130078217A1
公开(公告)日：2013-03-28
申请号：US13624093
申请日：2012-09-21
申请人： Guoqiang Wang , In Jong Kim , Yat Sun Or
发明人： Guoqiang Wang , In Jong Kim , Yat Sun Or
IPC分类号： C07H19/06 , C07H19/10 , A61K45/06 , C07H19/14 , C07H19/12 , A61K31/706 , C07H19/16 , A61K31/7076 , A61K31/7072 , A61K38/21
CPC分类号： C07H19/06 , A61K31/015 , A61K31/427 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K38/21 , A61K38/212 , A61K38/215 , A61K45/06 , C07H19/067 , C07H19/073 , C07H19/10 , C07H19/11 , C07H19/12 , C07H19/14 , C07H19/16 , C07H19/167 , C07H19/173 , C07H19/207 , C07H19/213 , A61K2300/00
摘要： The present invention relates to 2′-chloroacetylenyl-substituted nucleoside derivatives of the general formula (I): As well as pharmaceutical compositions comprising such compounds and methods to treat or prevent an HIV infection, HBV infection, HCV infection or abnormal cellular proliferation, comprising administering said compounds or compositions. In addition, the present invention includes processes for the preparation of such compounds, and the related β-D and β-L-nucleoside derivatives.
摘要翻译：本发明涉及通式（I）的2'-氯乙酰基取代的核苷衍生物：以及包含这些化合物的药物组合物以及治疗或预防HIV感染，HBV感染，HCV感染或异常细胞增殖的方法，包括给药所述化合物或组合物。此外，本发明包括制备这些化合物的方法，以及相关的β-和β-半胱氨酸衍生物。

3. 发明申请

US20090270415A1 COMPOUNDS THAT INHIBIT PROTEASE CATHEPSIN S AND HCV REPLICATION 失效
标题翻译：抑制蛋白激酶S和HCV复制的化合物
公开(公告)号：US20090270415A1
公开(公告)日：2009-10-29
申请号：US12256370
申请日：2008-10-22
申请人： Leslie Jean Holsinger , Kyle Elrod , John O. Link , Michael Graupe , In Jong Kim
发明人： Leslie Jean Holsinger , Kyle Elrod , John O. Link , Michael Graupe , In Jong Kim
IPC分类号： A61K31/497 , C07D403/12
CPC分类号： C07D403/12
摘要： The present invention is directed to compounds that have the dual property of acting as cathepsin S inhibitors and of inhibiting HCV replication. Such compounds are therefore useful in treating disease states that include hepatitis C, Alzheimer's disease, and autoimmune disorders. The present invention is also directed to pharmaceutical compositions containing these compounds, and processes for preparing the compounds.
摘要翻译：本发明涉及具有作为组织蛋白酶S抑制剂和抑制HCV复制的双重性质的化合物。因此，这样的化合物可用于治疗包括丙型肝炎，阿尔茨海默氏病和自身免疫性疾病的疾病状态。本发明还涉及含有这些化合物的药物组合物及其制备方法。

4. 发明申请

US20090264380A1 6,11-BRIDGED BIARYL MACROLIDES 有权
公开(公告)号：US20090264380A1
公开(公告)日：2009-10-22
申请号：US12399801
申请日：2009-03-06
申请人： In Jong Kim , Tongzhu Liu , Jiang Long , Guoqiang Wang , Yao-Ling Qiu , Heejin Kim , Yanchun Wang , Ly Tam Phan , Yat Sun Or
发明人： In Jong Kim , Tongzhu Liu , Jiang Long , Guoqiang Wang , Yao-Ling Qiu , Heejin Kim , Yanchun Wang , Ly Tam Phan , Yat Sun Or
IPC分类号： A61K31/7048 , C07H17/08 , A61P31/04 , A61P29/00
CPC分类号： C07D493/08 , C07F9/65586 , C07H17/08
摘要： The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了式I，II或X的化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

5. 发明授权

US06238668B1 Colon cancer KH-1 and N3 antigens 失效
标题翻译：结肠癌KH-1和N3抗原
公开(公告)号：US06238668B1
公开(公告)日：2001-05-29
申请号：US09042280
申请日：1998-01-13
申请人： Samuel J. Danishefsky , Prashant P. Deshpande , In Jong Kim , Philip Livingston , Hyun Jin Kim , Ragupathi Govindaswami , Tae Kyo Park
发明人： Samuel J. Danishefsky , Prashant P. Deshpande , In Jong Kim , Philip Livingston , Hyun Jin Kim , Ragupathi Govindaswami , Tae Kyo Park
IPC分类号： A61K3900
CPC分类号： C07H15/10 , A61K47/643 , A61K47/646
摘要： The present invention provides processes for the preparation of the KH-1 and N3 antigens, as well as related analgoues thereof, which are useful as anticancer therapeutics. The present invention also provides various intermediates useful in the preparation of KH-1 and N3 and analogues thereof. Additionally, the invention provides various compositions comprising any of the analogues of KH-1 and N3 available through the methods of the invention and pharmaceutical carriers useful in the treatment of subjects suffering from various forms of epithelial cancer.
摘要翻译：本发明提供了可用作抗癌治疗剂的KH-1和N3抗原的制备方法及其相关的方法。本发明还提供了可用于制备KH-1和N 3的各种中间体及其类似物。此外，本发明提供了包含可通过本发明方法获得的任何类似物的KH-1和N 3的各种组合物和可用于治疗患有各种形式的上皮癌的受试者的药物载体。

6. 发明授权

US5708163A Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof 失效
标题翻译：由单克隆抗体MBRL定义的乳腺肿瘤相关抗原的合成及其用途
公开(公告)号：US5708163A
公开(公告)日：1998-01-13
申请号：US430355
申请日：1995-04-28
申请人： Samuel J. Danishefsky , Mark T. Bilodeau , Shuang Hua Hu , Tae Kyo Park , John T. Randolph , In Jong Kim , Philip O. Livingston
发明人： Samuel J. Danishefsky , Mark T. Bilodeau , Shuang Hua Hu , Tae Kyo Park , John T. Randolph , In Jong Kim , Philip O. Livingston
IPC分类号： C07H11/00 , A61K31/70 , A61K31/7028 , A61K31/7042 , A61K31/7048 , A61K38/00 , A61K39/00 , A61K39/39 , A61P35/00 , A61P37/04 , C07H3/06 , C07H15/10 , C07H15/18 , C07H17/02 , C07H17/04 , C07K1/04 , C07K9/00 , C07K16/30 , C07K16/44 , C07H1/00 , C07H5/06 , C07H17/00 , C08B37/00
CPC分类号： C07H15/10 , A61K39/0011 , C07H15/18 , C07H17/02 , C07H3/06 , C07K1/04 , C07K16/3015 , C07K16/44 , C07K9/005 , A61K38/00
摘要： The present invention provides a process for synthesizing a compound having the structure: ##STR1## wherein R is H, as well as related oligosaccharides useful as a vaccine for inducing antibodies to human breast cancer cells in an adjuvant therapy therefor.
摘要翻译：本发明提供了一种合成具有以下结构的化合物的方法：其中R是H，以及可用作用于在其辅助治疗中诱导人乳腺癌细胞的抗体的疫苗的相关寡糖。

7. 发明授权

US08867686B2 High current solid target for radioisotope production at cyclotron using metal foam 有权
标题翻译：使用金属泡沫的回旋加速器放射性同位素生产的高电流固体靶
公开(公告)号：US08867686B2
公开(公告)日：2014-10-21
申请号：US12821949
申请日：2010-06-23
申请人： Min Goo Hur , Seung Dae Yang , Sang Wook Kim , In Jong Kim , Sang Mu Choi
发明人： Min Goo Hur , Seung Dae Yang , Sang Wook Kim , In Jong Kim , Sang Mu Choi
IPC分类号： G21G1/10 , H05H6/00
CPC分类号： H05H6/00
摘要： Disclosed herein is a high current solid target for radioisotope production at a cyclotron using a metal foam, and more specifically, a high current solid target for isotope production, which attaches a metal foam to the rear surface of the solid target plate. A high current solid target for isotope production including a metal foam according to the present invention may exhibit excellent cooling performances to increase the amount of proton beam current irradiated on the solid target compared to conventional planar-type solid targets. Because the irradiation of the increased proton beam current may increase the amount of an isotope produced per unit time and even an irradiation of proton beam in a short time may allow for production of a desired amount of an isotope, the solid target may be usefully used for production of medical cyclotron nuclides.
摘要翻译：本文公开了用于使用金属泡沫的回旋加速器的放射性同位素生产的高电流固体靶，更具体地，用于同位素产生的高电流固体靶，其将金属泡沫附着到固体靶板的后表面。与现有的平面型固体靶相比，含有根据本发明的金属泡沫的高电流固体靶可以表现出优异的冷却性能，以增加照射在固体靶上的质子束电流的量。因为增加的质子束电流的照射可以增加每单位时间产生的同位素的量，甚至在短时间内甚至照射质子束可以允许产生所需量的同位素，所以可以有用地使用固体靶用于生产医用回旋加速器核素。

8. 发明授权

US08575119B2 2′-chloroacetylenyl substituted nucleoside derivatives 有权
标题翻译： 2'-氯乙酰基取代的核苷衍生物
公开(公告)号：US08575119B2
公开(公告)日：2013-11-05
申请号：US13624093
申请日：2012-09-21
申请人： Guoqiang Wang , In Jong Kim , Yat Sun Or
发明人： Guoqiang Wang , In Jong Kim , Yat Sun Or
IPC分类号： A61K31/70 , C07H19/00 , C07H21/00
CPC分类号： C07H19/06 , A61K31/015 , A61K31/427 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K38/21 , A61K38/212 , A61K38/215 , A61K45/06 , C07H19/067 , C07H19/073 , C07H19/10 , C07H19/11 , C07H19/12 , C07H19/14 , C07H19/16 , C07H19/167 , C07H19/173 , C07H19/207 , C07H19/213 , A61K2300/00
摘要： The present invention relates to 2′-chloroacetylenyl-substituted nucleoside derivatives of the general formula (I): As well as pharmaceutical compositions comprising such compounds and methods to treat or prevent an HIV infection, HBV infection, HCV infection or abnormal cellular proliferation, comprising administering said compounds or compositions. In addition, the present invention includes processes for the preparation of such compounds, and the related β-D and β-L-nucleoside derivatives.
摘要翻译：本发明涉及通式（I）的2'-氯乙酰基取代的核苷衍生物：以及包含这些化合物的药物组合物以及治疗或预防HIV感染，HBV感染，HCV感染或异常细胞增殖的方法，包括给药所述化合物或组合物。此外，本发明包括制备这些化合物的方法和相关的β-D和β-L-核苷衍生物。

9. 发明申请

US20120237480A1 2'ALLENE-SUBSTITUTED NUCLEOSIDE DERIVATIVES 有权
标题翻译： 2'-取代的核苷衍生物
公开(公告)号：US20120237480A1
公开(公告)日：2012-09-20
申请号：US13422268
申请日：2012-03-16
申请人： YAT SUN OR , Jun Ma , Guoqiang Wang , In Jong Kim , Jiang Long , Yao-Ling Qiu
发明人： YAT SUN OR , Jun Ma , Guoqiang Wang , In Jong Kim , Jiang Long , Yao-Ling Qiu
IPC分类号： A61K31/706 , C07H19/12 , C07H19/173 , C07H19/044 , C07H19/10 , C07H19/20 , C07H19/11 , C07H19/213 , A61K31/7076 , A61K31/708 , A61K31/7068 , A61K31/7072 , A61P31/14 , A61K38/21 , A61P31/04 , A61P31/10 , A61P35/00 , A61P37/02 , C07H19/073
CPC分类号： C07H19/06 , A61K31/7056 , A61K31/706 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K31/708 , A61K38/55 , A61K45/06 , A61K2300/00 , A61K31/426 , A61K31/13
摘要： The present invention relates to 2′-allene-substituted nucleoside derivatives of the general formula (I): As well as pharmaceutical compositions comprising such compounds and methods to treat or prevent an HIV infection, HBV infection, HCV infection or abnormal cellular proliferation, comprising administering said compounds or compositions. In addition, the present invention includes processes for the preparation of such compounds, and the related β-D and β-L-nucleoside derivatives.
摘要翻译：本发明涉及通式（I）的2'-连烯取代的核苷衍生物：以及包含这些化合物的药物组合物以及治疗或预防HIV感染，HBV感染，HCV感染或异常细胞增殖的方法，包括给药所述化合物或组合物。此外，本发明包括制备这些化合物的方法，以及相关的β-和β-半胱氨酸衍生物。

10. 发明申请

US20090209547A1 C-8 HALOGENATED MACROLIDES 审中-公开
标题翻译： C-8对羟基苯甲酸
公开(公告)号：US20090209547A1
公开(公告)日：2009-08-20
申请号：US12370805
申请日：2009-02-13
申请人： IN JONG KIM , GUOQIANG WANG , HEEJIN KIM , YAT SUN OR
发明人： IN JONG KIM , GUOQIANG WANG , HEEJIN KIM , YAT SUN OR
IPC分类号： A61K31/4985 , A61K31/4375 , A61K31/4439 , A61K31/424 , C07D471/04 , C07D498/04
CPC分类号： C07D498/04 , C07D405/14 , C07D407/12 , C07D407/14 , C07D471/04 , C07D493/04
摘要： The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
摘要翻译：本发明公开了具有抗菌性质的式（I）化合物或其药学上可接受的盐，酯或前药。本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。本发明还包括制备本发明化合物的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式