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1. 发明授权

US07554090B2 Apparatus and process for dose-guided radiotherapy 有权
标题翻译：剂量引导放疗的装置和方法
公开(公告)号：US07554090B2
公开(公告)日：2009-06-30
申请号：US10548391
申请日：2005-03-04
申请人： C. Norman Coleman , Robert Miller , Rosemary Altemus , Holly Ning , Alan Lee Huston , Brian L. Justus , Paul Falkenstein
发明人： C. Norman Coleman , Robert Miller , Rosemary Altemus , Holly Ning , Alan Lee Huston , Brian L. Justus , Paul Falkenstein
IPC分类号： G01T1/16
CPC分类号： A61N5/1048 , A61N5/1064 , A61N5/1071 , A61N2005/1072
摘要： A method and an apparatus for dose-guided radiotherapy for a patient (P) having an identified radiotherapy target utilizes a radiation detecting array (R) of radiation-sensitive dosimeters for the real-time remote measurement of radiotherapy at the radiation detecting array (R). The radiation detecting array is positioned within the patient's (P) body along the treatment path before or after the identified radiotherapy target or the device may be positioned beyond the patient (P) to measure transit dose. A radiation source (A) for emitting radiation for radiotherapy along a treatment path through the patient (P) to the identified radiotherapy target is utilized. The method includes generating a predicted dose pattern of radiation at the placed radiation detecting array (R). The predicted dose pattern assumes an on-target radiation source (A) emitting the radiotherapy beam along the treatment path through the patient (P) to the identified radiotherapy target. Gating of the radiation source (A) can occur responsive to the comparing of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R). Radiation intensity can vary between low levels to a treatment level responsive to coincidence of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R).
摘要翻译：用于具有识别的放射治疗靶标的患者（P）的剂量引导放射治疗的方法和装置利用辐射敏感剂量计的放射线检测阵列（R）用于放射线检测阵列（R）处的放射治疗的实时远程测量）。放射线检测阵列沿着治疗路径位于患者的（P）体内，在识别的放射治疗靶标之前或之后，或者该装置可以位于患者（P）之外，以测量转运剂量。利用用于沿着通过患者（P）的治疗路径发射放射线的辐射源（A）到所识别的放射治疗靶标。该方法包括在放置的放射线检测阵列（R）处产生辐射的预测剂量图案。预测的剂量模式假设沿着经由患者（P）的治疗路径发射放射治疗束到被识别的放射治疗靶标的靶标辐射源（A）。辐射源（A）的门控可以响应于放射线检测阵列（R）的预测辐射剂量模式与实时剂量模式的比较而发生。辐射强度可以根据预测的辐射剂量模式与放射线检测阵列（R）处的实时剂量图案的一致性，在低水平与治疗水平之间变化。

2. 发明申请

US20070058778A1 Apparatus and process for dose-guided radiotherapy 有权
标题翻译：剂量引导放疗的装置和方法
公开(公告)号：US20070058778A1
公开(公告)日：2007-03-15
申请号：US10548391
申请日：2004-03-04
申请人： C. Coleman , Robert Miller , Rosemary Altemus , Holly Ning , Alan Huston , Brian Justus , Paul Falkenstein
发明人： C. Coleman , Robert Miller , Rosemary Altemus , Holly Ning , Alan Huston , Brian Justus , Paul Falkenstein
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1064 , A61N5/1071 , A61N2005/1072
摘要： A method and an apparatus for dose-guided radiotherapy for a patient (P) having an identified radiotherapy target utilizes a radiation detecting array (R) of radiation-sensitive dosimeters for the real-time remote measurement of radiotherapy at the radiation detecting array (R). The radiation detecting array is positioned within the patient's (P) body along the treatment path before or after the identified radiotherapy target or the device may be positioned beyond the patient (P) to measure transit dose. A radiation source (A) for emitting radiation for radiotherapy along a treatment path through the patient (P) to the identified radiotherapy target is utilized. The method includes generating a predicted dose pattern of radiationa at the placed radiation detecting array (R). The predicted dose pattern assumes an on-target radiation source (A) emitting the radiotherapy beam along the treatment path through the patient (P) to the identified radiotherapy target. Gating of the radiation source (A) can occur responsive to the comparing of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R). Radiation intensity can vary between low levels to a treatment level responsive to coincidence of the predicted dose pattern of radiation to the real-time dose pattern at the radiation detecting array (R).
摘要翻译：用于具有识别的放射治疗靶标的患者（P）的剂量引导放射治疗的方法和装置利用辐射敏感剂量计的放射线检测阵列（R）用于放射线检测阵列（R）处的放射治疗的实时远程测量）。放射线检测阵列沿着治疗路径位于患者的（P）体内，在识别的放射治疗靶标之前或之后，或者该装置可以位于患者（P）之外，以测量转运剂量。利用用于沿着通过患者（P）的治疗路径发射放射线的辐射源（A）到所识别的放射治疗靶标。该方法包括在放置的放射线检测阵列（R）处产生辐射的预测剂量图案。预测的剂量模式假设沿着经由患者（P）的治疗路径发射放射治疗束到被识别的放射治疗靶标的靶标辐射源（A）。辐射源（A）的门控可以响应于放射线检测阵列（R）的预测辐射剂量模式与实时剂量模式的比较而发生。辐射强度可以根据预测的辐射剂量模式与放射线检测阵列（R）处的实时剂量图案的一致性，在低水平与治疗水平之间变化。

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