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1. 发明申请

US20170101364A1 (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and Related Compounds as GABA Aminotransferase Inactivators for the Treatment of Epilepsy, Addiction and Hepatocellular Carcinoma 有权
公开(公告)号：US20170101364A1
公开(公告)日：2017-04-13
申请号：US15289480
申请日：2016-10-10
申请人： Richard B. Silverman , Kenji Takaya , Hoang V. Le , Jose I. Juncosa
发明人： Richard B. Silverman , Kenji Takaya , Hoang V. Le , Jose I. Juncosa
IPC分类号： C07C229/48
CPC分类号： A61K31/196 , C07C229/48 , C07C2601/10
摘要： Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.

2. 发明授权

US06387853B1 Derivatization of polymers and well treatments using the same 失效
标题翻译：聚合物的衍生和使用其的井处理
公开(公告)号：US06387853B1
公开(公告)日：2002-05-14
申请号：US09049610
申请日：1998-03-27
申请人： Jeffrey C. Dawson , Subramanian Kesavan , Hoang V. Le
发明人： Jeffrey C. Dawson , Subramanian Kesavan , Hoang V. Le
IPC分类号： C09K300
CPC分类号： C09K8/90 , C08B37/0096 , C09K8/08 , C09K8/32 , C09K8/52 , C09K8/64 , C09K8/685 , C09K8/74 , C09K8/887 , Y10S507/922
摘要： Polymers are derivatized and then may be introduced into a wellbore, such as in a hydraulic fracturing treatment. A polymer may be a guar powder that is mixed with a organic solvent and derivatized using a derivatizing agent, such as sodium chloroacetate. The polymer is typically derivatized in bulk prior to introduction into the wellbore. The derivatized polymer may be hydrated and/or crosslinked prior to introduction into the wellbore.
摘要翻译：聚合物被衍生化，然后可以引入井眼，例如在水力压裂处理中。聚合物可以是与有机溶剂混合并且使用衍生剂如氯乙酸钠衍生化的瓜尔胶粉末。在引入井眼之前，聚合物通常在体积中衍生化。在引入井筒之前，衍生的聚合物可以是水合和/或交联的。

3. 发明授权

US06169058A Compositions and methods for hydraulic fracturing 失效
$Compositions and methods for hydraulic fracturing$
标题翻译：水力压裂的组成和方法
公开(公告)号：US06169058A
公开(公告)日：2001-01-02
申请号：US08869388
申请日：1997-06-05
申请人： Hoang V. Le , Subramanian Kesavan , Jeffrey C. Dawson , David J. Mack , Scott G. Nelson
发明人： Hoang V. Le , Subramanian Kesavan , Jeffrey C. Dawson , David J. Mack , Scott G. Nelson
IPC分类号： C09K702
CPC分类号： C09K8/64 , C09K8/62 , C09K8/80 , Y10S507/903 , Y10S507/922 , Y10S507/924
摘要： A subterranean formation is treated by introducing a fracturing treatment composition comprising a polymer treatment fluid containing a dispersion of hydrophilic water swellable particles into the formation. The water swellable particles comprise synthetic polymers that are crosslinked so that they are water insoluble, but capable of swelling in the presence of relatively small amounts of water. When used with treatment fluids containing at least a small amount of water, the particles swell and reduce fluid loss to the formation during the treatment. When used during a hydraulic fracturing treatment of a hydrocarbon bearing formation, the particles may also reduce or eliminate water production following the fracturing treatment by restricting the extension of a fracture into water-bearing formations, and/or by restricting the flow of fluids from water-bearing areas.
摘要翻译：通过将包含含有亲水性水可溶胀颗粒分散体的聚合物处理流体的压裂处理组合物引入地层来处理地层。水可溶胀颗粒包括交联的合成聚合物，使得它们是水不溶性的，但在相对少量的水的存在下能够溶胀。当与含有至少少量水的处理流体一起使用时，颗粒在处理期间膨胀并减少对地层的流体损失。当在含烃地层的水力压裂处理中使用时，颗粒还可以通过将断裂延伸到含水地层中和/或通过限制流体从水中的流动来减少或消除压裂处理后的水产生 - 区域。

4. 发明授权

US5447199A Controlled degradation of polymer based aqueous gels 失效
标题翻译：聚合物基水凝胶的受控降解
公开(公告)号：US5447199A
公开(公告)日：1995-09-05
申请号：US86783
申请日：1993-07-02
申请人： Jeffrey C. Dawson , Hoang V. Le
发明人： Jeffrey C. Dawson , Hoang V. Le
IPC分类号： C09K8/68 , E21B43/26
CPC分类号： C09K8/685 , Y10S507/921 , Y10S507/922
摘要： A method of fracturing a subterranean formation in a well bore is shown in which a gellable fracturing fluid is first formed by blending together an aqueous fluid, a hydratable polymer, a suitable crosslinking agent for crosslinking the hydratable polymer to form a polymer gel and a breaker comprising a slightly water soluble, organic peroxide. The crosslinked polymer gel is pumped into the well bore under sufficient pressure to fracture the surrounding formation. The breaker is allowed to degrade the crosslinked polymer with time to reduce the viscosity of the fluid so that the fluid can be pumped from the formation back to the well surface.
摘要翻译：示出了在井眼中压裂地层的方法，其中首先通过将水性流体，可水合聚合物，用于交联可水合聚合物以形成聚合物凝胶和断路器的合适的交联剂共混在一起形成可凝胶化的压裂流体包含微溶于水的有机过氧化物。交联的聚合物凝胶在足够的压力下被泵送到井眼中以破坏周围的地层。允许断路器随时间降解交联聚合物以降低流体的粘度，使得流体可以从地层泵送回井表面。

5. 发明授权

US06228812B1 Compositions and methods for selective modification of subterranean formation permeability 有权
标题翻译：选择性改性地层渗透性的组合物和方法
公开(公告)号：US06228812B1
公开(公告)日：2001-05-08
申请号：US09286179
申请日：1999-04-05
申请人： Jeffrey C. Dawson , Hoang V. Le , Subramanian Kesavan
发明人： Jeffrey C. Dawson , Hoang V. Le , Subramanian Kesavan
IPC分类号： C09K300
CPC分类号： C08F226/02 , C08F220/56 , C08F220/58
摘要： Compositions and methods for modifying the permeability of subterranean formations for the purpose of selectively reducing excessive production of aqueous fluids. The compositions include copolymers which may be added to an aqueous fluid to form a water control treatment fluid. The copolymers may include copolymers having a hydrophillic monomeric unit, a first anchoring monomeric unit and a filler monomeric unit, with the first anchoring monomeric unit being based on N-vinylformamide. Additional anchoring monomeric units may also optionally be present. The copolymers may be employed in well treatment fluids introduced into production wells or injection wells. The copolymers may also be utilized in conjunction with stimulation treatments and with introduction of other well treatment fluids.
摘要翻译：为了选择性地减少含水流体的过量生产的目的，改变地下地层的渗透性的组合物和方法。组合物包括可以加入到含水流体中以形成水控制处理流体的共聚物。共聚物可以包括具有亲水单体单元，第一锚定单体单元和填料单体单元的共聚物，其中第一锚定单体单元基于N-乙烯基甲酰胺。还可以任选地存在另外的锚定单体单元。共聚物可用于引入生产井或注入井的井处理流体。共聚物也可以与刺激处理结合使用并引入其它良好的处理流体。

6. 发明授权

US5226481A Method for increasing the stability of water-based fracturing fluids 失效
$Method for increasing the stability of water-based fracturing fluids$
标题翻译：提高水性压裂液稳定性的方法
公开(公告)号：US5226481A
公开(公告)日：1993-07-13
申请号：US846688
申请日：1992-03-04
申请人： Hoang V. Le , William R. Wood
发明人： Hoang V. Le , William R. Wood
IPC分类号： C09K8/68
CPC分类号： C09K8/685 , Y10S507/922
摘要： A method for increasing the stability of water-based fracturing fluids is shown in which a base fracturing fluid is formulated by mixing together a hard mix water containing multivalent cations, a water soluble polymer and a cross-linking agent for the water soluble polymer. A water softener is added to the base fracturing fluid which hinders the ability of the multivalent cations present in the hard mix water to compete with the water soluble polymer for borate based cross-linking agent, thereby stabilizing the resulting fracturing fluid.
摘要翻译：示出了提高水性压裂液稳定性的方法，其中通过将含有多价阳离子的硬混合水，水溶性聚合物和用于水溶性聚合物的交联剂混合在一起来配制基础压裂液。将水软化剂添加到基础压裂液中，这阻碍了硬混合水中存在的多价阳离子与硼酸盐基交联剂的水溶性聚合物竞争的能力，从而使得到的压裂液稳定。

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