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1. 发明授权

US09125810B2 Alginic acid-containing aqueous composition, dental alginate impression material, and base material for dental alginate impression material 有权
标题翻译：含海藻酸的水性组合物，海藻酸海藻酸盐印象材料和用于牙科藻酸盐印象材料的基材
公开(公告)号：US09125810B2
公开(公告)日：2015-09-08
申请号：US13641197
申请日：2011-04-20
申请人： Hidetoshi Gyakushi , Koji Matsushige , Yuko Nagasawa
发明人： Hidetoshi Gyakushi , Koji Matsushige , Yuko Nagasawa
IPC分类号： A61K6/10 , A61K6/00
CPC分类号： A61K6/0088 , A61K6/0047 , A61K6/10 , C08L5/04 , C08L5/16
摘要： Provided is an aqueous composition containing alginic acid or a derivative thereof, the composition having a viscosity retained stably over a long period of time. The alginic acid-containing aqueous composition includes alginic acid or a derivative thereof (A), water (B), and a non-reducing sugar (C). Also provided are a dental alginate impression material and a base material for a dental alginate impression material each using the composition, in which the viscosity of the aqueous composition is stably maintained for a long period.
摘要翻译：本发明提供含有海藻酸或其衍生物的水性组合物，该组合物具有长时间稳定的粘度。含海藻酸的水性组合物包括藻酸或其衍生物（A），水（B）和非还原糖（C）。还提供了藻酸盐印模材料和用于海藻酸盐印模材料的基材，每种使用该组合物，其中水性组合物的粘度长期稳定地保持。

2. 发明授权

US08470986B2 Method for production of sugar oxazoline derivative 有权
标题翻译：糖恶唑啉衍生物的制备方法
公开(公告)号：US08470986B2
公开(公告)日：2013-06-25
申请号：US12528547
申请日：2008-03-07
申请人： Shinichiro Shoda , Atsushi Kobayashi , Masato Noguchi , Tomonari Tanaka , Hidetoshi Gyakushi
发明人： Shinichiro Shoda , Atsushi Kobayashi , Masato Noguchi , Tomonari Tanaka , Hidetoshi Gyakushi
IPC分类号： C07H17/02
CPC分类号： C07H9/06 , C08B37/0069
摘要： A method for producing an oxazoline derivative from a non-protected sugar in a simple manner and a method for producing a glycoside by utilizing the product of the aforementioned method are disclosed. A sugar oxazoline derivative is synthesized in one step in an aqueous solution from a sugar having a free hemiacetal hydroxy group and an amide group by using a haloformamidinium derivative as a dehydration/condensation agent. A glycoside is produced by using the oxazolidine derivative as a sugar donor and also using a sugar dehydrogenase. The method can be applied to the production of a compound having a long sugar chain, and is therefore useful for a production of a physiologically active oligosaccharide, a carrier for a drug delivery system, a surfactant, a carbohydrate pharmaceutical, a glycopeptide, a glycoprotein, a carbohydrate polymer or the like.
摘要翻译：公开了以简单方式从非保护性糖制备恶唑啉衍生物的方法和利用上述方法的产物制备糖苷的方法。通过使用卤代甲脒衍生物作为脱水/缩合剂，在具有游离半缩醛羟基和酰胺基的糖的水溶液中一步合成糖恶唑啉衍生物。通过使用恶唑烷衍生物作为糖供体并且还使用糖脱氢酶来生产糖苷。该方法可用于生产具有长糖链的化合物，因此可用于生产生物活性寡糖，药物递送系统的载体，表面活性剂，碳水化合物药物，糖肽，糖蛋白，碳水化合物聚合物等。

3. 发明申请

US20110098375A1 DENTAL ADHESIVE COMPOSITION 有权
标题翻译：牙膏组合物
公开(公告)号：US20110098375A1
公开(公告)日：2011-04-28
申请号：US12999464
申请日：2009-07-22
申请人： Hidetoshi Gyakushi , Takeshi Suzuki , Mihoko Kajikawa , Hideki Kazama
发明人： Hidetoshi Gyakushi , Takeshi Suzuki , Mihoko Kajikawa , Hideki Kazama
IPC分类号： A61K6/08
CPC分类号： A61K6/0023 , C08L43/02
摘要： [Problems] A dental adhesive composition containing an acid group-containing polymerizable monomer, that can be used as a dental adhesive material or a primer. The dental adhesive composition has excellent durability of adhesion exhibiting further improved adhering strength and durability of adhesion enabling teeth to be more strongly adhered to a composite resin or a prosthetic over extended periods of time.[Means for Solution] The dental adhesive composition contains a polymerizable monomer and ions of an element of the Group IV as basic components, at least 10 mass % of the polymerizable monomer being a polymerizable monomer having a hydrogenphosphate diester group, such as bis(2-methacryloyloxyethyl)hydrogenphosphate or 2-methacryloyloxyethylphenyl hydrogenphosphate, and the content of ions of the element of the Group IV such as titanium ions or zirconium ions in the composition being 0.1 to 1.0 in terms of mole ratio to the hydrogenphosphate diester groups of the polymerizable monomer that has the hydrogenphosphate diester group.
摘要翻译： [问题]含有含酸基的可聚合单体的牙科粘合剂组合物，其可以用作牙科粘合剂材料或底漆。牙科粘合剂组合物具有优异的粘合耐久性，其显示出进一步改善的粘合强度和粘合的耐久性，使得齿能够在长时间内更加牢固地粘附到复合树脂或假体上。 [解决方案]牙科用粘合剂组合物含有聚合性单体和IV族元素作为碱性成分的离子，至少10质量％的可聚合单体是具有磷酸二酯基的可聚合单体，例如双（2 - 甲基丙烯酰氧基乙基）磷酸氢盐或2-甲基丙烯酰氧基乙基苯基磷酸氢盐，组合物中IV族元素如钛离子或锆离子的离子含量与可聚合单体的磷酸氢二酯基的摩尔比为0.1至1.0 具有磷酸氢二酯组。

4. 发明授权

US08985399B2 Knock-type ejection container 有权
标题翻译：敲门式弹出容器
公开(公告)号：US08985399B2
公开(公告)日：2015-03-24
申请号：US13820529
申请日：2011-09-05
申请人： Hidetoshi Gyakushi , Nobutoshi Yamaguchi
发明人： Hidetoshi Gyakushi , Nobutoshi Yamaguchi
IPC分类号： B67D7/06 , B65D35/24 , A61C5/06 , A61M3/00
CPC分类号： B65D35/24 , A61C5/62 , A61M3/00
摘要： [Problems] To provide an ejection container capable of falling a liquid in drops from the container body without relying on the sense of the fingertips and without affected by a change in the temperature.[Means for Solution] A knock-type ejection container 1 in which an ejection port 8 is provided at one end of a container body 2, a knock button 4 is provided at the other end thereof, a container chamber 22 is provided in the container body 2 to contain a liquid, and the liquid contained in the container chamber 22 is ejected from the ejection port 8 being interlocked to the operation of the knock button 4.
摘要翻译： [问题]提供一种能够从容器主体滴落液体的喷射容器，而不依赖于指尖的感觉而不受温度变化的影响。 [解决方案]在容器主体2的一端设置有排出口8的爆震式喷出容器1，在其另一端设置有敲击按钮4，容器室22设置在容器主体2容纳液体，并且容纳在容器室22中的液体从与敲击按钮4的操作互锁的喷射口8喷射。

5. 发明申请

US20130220172A1 ALGINATE IMPRESSION MATERIAL FOR DENTAL USE AND CURING AGENT PASTE USED THEREFOR 有权
标题翻译：用于牙科用途的牙膏印花材料及其使用的固化剂
公开(公告)号：US20130220172A1
公开(公告)日：2013-08-29
申请号：US13884510
申请日：2011-10-21
申请人： Yuko Nagasawa , Koji Matsushige , Hidetoshi Gyakushi
发明人： Yuko Nagasawa , Koji Matsushige , Hidetoshi Gyakushi
IPC分类号： A61K6/10
CPC分类号： A61K6/10 , C08L5/04
摘要： To suppress a curing agent paste stored in a sealed state in a packaging container from self-curing over a long period of time, provided are a dental alginate impression material as described below, and a curing agent paste to be used for the dental alginate impression material. The dental alginate impression material may includes: a base material paste including as main components: an alginic acid salt (A); and water (B); and a curing agent paste including as main components: a gelling reaction agent (C); a poorly water-soluble organic solvent (D); and a humectant (E).
摘要翻译：为了将密封状态的密封状态的固化剂糊料长时间自固化，可以使用如下所述的海藻酸印模材料和用于牙科藻酸盐印象的固化剂糊剂材料。海藻酸印迹材料可以包括：作为主要成分的基材膏，藻酸盐（A）; 和水（B）; 和作为主要成分的固化剂糊剂：胶凝反应剂（C）; 水溶性差的有机溶剂（D）; 和保湿剂（E）。

6. 发明授权

US09125818B2 Alginate impression material for dental use and curing agent paste used therefor 有权
标题翻译：用于牙科用途的藻酸盐印模材料和用于其的固化剂糊剂
公开(公告)号：US09125818B2
公开(公告)日：2015-09-08
申请号：US13884510
申请日：2011-10-21
申请人： Yuko Nagasawa , Koji Matsushige , Hidetoshi Gyakushi
发明人： Yuko Nagasawa , Koji Matsushige , Hidetoshi Gyakushi
IPC分类号： A61K6/10
CPC分类号： A61K6/10 , C08L5/04
摘要： To suppress a curing agent paste stored in a sealed state in a packaging container from self-curing over a long period of time, provided are a dental alginate impression material as described below, and a curing agent paste to be used for the dental alginate impression material. The dental alginate impression material may includes: a base material paste including as main components: an alginic acid salt (A); and water (B); and a curing agent paste including as main components: a gelling reaction agent (C); a poorly water-soluble organic solvent (D); and a humectant (E).
摘要翻译：为了将密封状态的密封状态的固化剂糊料长时间自固化，可以使用如下所述的海藻酸印模材料和用于牙科藻酸盐印象的固化剂糊剂材料。海藻酸印迹材料可以包括：作为主要成分的基材膏，藻酸盐（A）; 和水（B）; 和作为主要成分的固化剂糊剂：胶凝反应剂（C）; 水溶性差的有机溶剂（D）; 和保湿剂（E）。

7. 发明申请

US20130175300A1 KNOCK-TYPE EJECTION CONTAINER 有权
标题翻译：卡诺式喷射容器
公开(公告)号：US20130175300A1
公开(公告)日：2013-07-11
申请号：US13820529
申请日：2011-09-05
申请人： Hidetoshi Gyakushi , Nobutoshi Yamaguchi
发明人： Hidetoshi Gyakushi , Nobutoshi Yamaguchi
IPC分类号： B65D35/24
CPC分类号： B65D35/24 , A61C5/62 , A61M3/00
摘要： [Problems] To provide an ejection container capable of falling a liquid in drops from the container body without relying on the sense of the fingertips and without affected by a change in the temperature.[Means for Solution] A knock-type ejection container 1 in which an ejection port 8 is provided at one end of a container body 2, a knock button 4 is provided at the other end thereof, a container chamber 22 is provided in the container body 2 to contain a liquid, and the liquid contained in the container chamber 22 is ejected from the ejection port 8 being interlocked to the operation of the knock button 4.
摘要翻译： [问题]提供一种能够从容器主体滴落液体的喷射容器，而不依赖于指尖的感觉而不受温度变化的影响。 [解决方案]在容器主体2的一端设置有排出口8的爆震式喷出容器1，在其另一端设置有敲击按钮4，容器室22设置在容器主体2容纳液体，并且容纳在容器室22中的液体从与敲击按钮4的操作互锁的喷射口8喷射。

8. 发明申请

US20130032058A1 ALGINIC ACID-CONTAINING AQUEOUS COMPOSITION, DENTAL ALGINATE IMPRESSION MATERIAL, AND BASE MATERIAL FOR DENTAL ALGINATE IMPRESSION MATERIAL 有权
标题翻译：含酸性水性组合物，牙膏ALGINATE IMPRESSION材料和基础材料用于牙科ALGINATE IMPRESSION MATERIAL
公开(公告)号：US20130032058A1
公开(公告)日：2013-02-07
申请号：US13641197
申请日：2011-04-20
申请人： Hidetoshi Gyakushi , Koji Matsushige , Yuko Nagasawa
发明人： Hidetoshi Gyakushi , Koji Matsushige , Yuko Nagasawa
IPC分类号： A61K6/10
CPC分类号： A61K6/0088 , A61K6/0047 , A61K6/10 , C08L5/04 , C08L5/16
摘要： Provided is an aqueous composition containing alginic acid or a derivative thereof, the composition having a viscosity retained stably over a long period of time. The alginic acid-containing aqueous composition includes alginic acid or a derivative thereof (A), water (B), and a non-reducing sugar (C). Also provided are a dental alginate impression material and a base material for a dental alginate impression material each using the composition, in which the viscosity of the aqueous composition is stably maintained for a long period.
摘要翻译：本发明提供含有海藻酸或其衍生物的水性组合物，该组合物具有长时间稳定的粘度。含海藻酸的水性组合物包括藻酸或其衍生物（A），水（B）和非还原糖（C）。还提供了藻酸盐印模材料和用于海藻酸盐印模材料的基材，每种使用该组合物，其中水性组合物的粘度长期稳定地保持。

9. 发明授权

US08796354B2 Dental adhesive composition 有权
标题翻译：牙科粘合剂组成
公开(公告)号：US08796354B2
公开(公告)日：2014-08-05
申请号：US12999464
申请日：2009-07-22
申请人： Hidetoshi Gyakushi , Takeshi Suzuki , Mihoko Kajikawa , Hideki Kazama
发明人： Hidetoshi Gyakushi , Takeshi Suzuki , Mihoko Kajikawa , Hideki Kazama
IPC分类号： C08L43/02
CPC分类号： A61K6/0023 , C08L43/02
摘要： [Problems] A dental adhesive composition containing an acid group-containing polymerizable monomer, that can be used as a dental adhesive material or a primer. The dental adhesive composition has excellent durability of adhesion exhibiting further improved adhering strength and durability of adhesion enabling teeth to be more strongly adhered to a composite resin or a prosthetic over extended periods of time.[Means for Solution] The dental adhesive composition contains a polymerizable monomer and ions of an element of the Group IV as basic components, at least 10 mass % of the polymerizable monomer being a polymerizable monomer having a hydrogenphosphate diester group, such as bis(2-methacryloyloxyethyl)hydrogenphosphate or 2-methacryloyloxyethylphenyl hydrogenphosphate, and the content of ions of the element of the Group IV such as titanium ions or zirconium ions in the composition being 0.1 to 1.0 in terms of mole ratio to the hydrogenphosphate diester groups of the polymerizable monomer that has the hydrogenphosphate diester group.
摘要翻译： [问题]含有含酸基的可聚合单体的牙科粘合剂组合物，其可以用作牙科粘合剂材料或底漆。牙科粘合剂组合物具有优异的粘合耐久性，其显示出进一步改善的粘合强度和粘合的耐久性，使得齿能够在长时间内更加牢固地粘附到复合树脂或假体上。 [解决方案]牙科用粘合剂组合物含有聚合性单体和IV族元素作为碱性成分的离子，至少10质量％的可聚合单体是具有磷酸二酯基的可聚合单体，例如双（2 - 甲基丙烯酰氧基乙基）磷酸氢盐或2-甲基丙烯酰氧基乙基苯基磷酸氢盐，组合物中IV族元素如钛离子或锆离子的离子含量与可聚合单体的磷酸氢二酯基的摩尔比为0.1至1.0 具有磷酸氢二酯组。

10. 发明申请

US20120160718A1 LIQUID MIXING CONTAINER 审中-公开
标题翻译：液体混合容器
公开(公告)号：US20120160718A1
公开(公告)日：2012-06-28
申请号：US13394260
申请日：2010-08-20
申请人： Nobutoshi Yamaguchi , Hidetoshi Gyakushi
发明人： Nobutoshi Yamaguchi , Hidetoshi Gyakushi
IPC分类号： B65D25/08
CPC分类号： B01F13/0033 , A61C3/005 , A61C5/60 , A61C5/68 , B01F15/0215 , B01F15/0226
摘要： [Problems] To provide a two-liquid mixing container which prevents two liquids from being mixed together by erroneous operation and does not permit sheet-like contaminants from mixing into the mixed liquid.[Means for Solution] A container body 2 of the two-liquid mixing container 1 is provided with liquid injection openings 7a, 8a for feeding different treating solutions into a plurality of liquid chambers 7, 8. A liquid chamber opening/closing member 4 is provided with sealing members which are fitted into one end side of the container body 2 and, at an advanced position of having entered into the liquid injection openings, work to close the liquid injection openings 7a, 8a to separately close the liquid chambers 7, 8 and, at a reversed position, work to open the liquid injection openings 7a, 8a permitting the liquid chambers 7, 8 to be communicated with each other.
摘要翻译： [问题]提供一种防止两种液体通过错误操作混合在一起并且不允许片状污染物混入混合液体的双液体混合容器。 [解决方案]双液混合容器1的容器主体2设置有用于将不同处理溶液供给到多个液体室7,8中的液体注入口7a，8a。液体室开闭部件4 设置有装配在容器主体2的一端侧的密封构件，并且在进入液体注入口的前进位置进行加工以封闭液体注入口7a，8a以分开封闭液体室7,8 并且在反转位置工作以打开允许液体室7,8彼此连通的液体喷射开口7a，8a。

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