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1. 发明授权

US09936931B2 Bone density measuring device 有权
公开(公告)号：US09936931B2
公开(公告)日：2018-04-10
申请号：US15023824
申请日：2014-09-18
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Ryutaro Adachi , Yasuo Nakamura , Naoto Kato
IPC分类号： A61B6/00 , A61B6/04
CPC分类号： A61B6/5217 , A61B6/04 , A61B6/0407 , A61B6/4405 , A61B6/4435 , A61B6/505 , A61B6/54
摘要： In image data obtained, the radius and the ulna, and interosseous soft tissue between two bones are identified. A midpoint (Ygk) of the length of the interosseous soft tissue in a Y axis direction in (Xk) coordinates is determined. This midpoint is determined in multiple coordinates, and an approximate straight line of these midpoints is determined and set as a reference line. The foot of the perpendicular from the ulna styloid process to the reference line is set as a reference position. A region of interest is set in a position at a predetermined distance from the reference position along the reference line.

2. 发明授权

US09688777B2 Protein-polymer complex, TGase substrate-containing polymer, TGase substrate-containing monomer, method for producing protein-polymer complex, and method for improving protein function at solid-liquid interface or in vicinity of solid-liquid interface 有权
公开(公告)号：US09688777B2
公开(公告)日：2017-06-27
申请号：US14392208
申请日：2014-06-27
申请人： KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION , HITACHI ALOKA MEDICAL, LTD.
发明人： Noriho Kamiya , Rie Wakabayashi , Kensuke Yahiro , Kounosuke Hayashi
IPC分类号： C07K17/08 , C07K14/00 , G01N33/68 , C07K5/062 , C07K14/315 , C08G61/12 , C12N9/42 , C12N9/96 , G01N33/543
CPC分类号： C07K17/08 , C07K5/06034 , C07K14/00 , C07K14/315 , C08G61/128 , C08G2261/1426 , C08G2261/1432 , C08G2261/148 , C08G2261/94 , C12N9/2437 , C12N9/96 , C12Y302/01004 , G01N33/54306 , G01N33/68
摘要： Provided is a protein-polymer complex which is capable of detecting a target with good sensitivity. Specifically provided is a protein-polymer complex comprising a polymer having a glutamine (Gln) residue or a primary amine on a side chain, wherein either a protein having a primary amine is bound to the glutamine (Gln) residue, or a protein having a glutamine (Gln) residue is bound to the primary amine.

3. 发明授权

US09482747B2 Mobile ultrasonic diagnostic device 有权
标题翻译：移动式超声波诊断装置
公开(公告)号：US09482747B2
公开(公告)日：2016-11-01
申请号：US14369989
申请日：2012-12-07
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Masa Yamamoto , Keigo Ninomiya
IPC分类号： G01S7/52 , A61B8/00 , A61B8/14
CPC分类号： G01S7/52 , A61B8/14 , A61B8/4427 , A61B8/54 , A61B8/56
摘要： A mobile ultrasonic diagnostic device comprising: a battery; an adapter connection detection unit that detects the connection status of an AC adapter that supplies power to each constituent element of the device; and a processing determination unit (determination unit) that determines the processing for each constituent element on the basis of the connection status of the AC adapter. Each constituent element (a processing unit and constituent elements other than the processing unit) are processed on the basis of the processing determined by the processing determination unit (determination unit), and, as a result, the device can be safely used even if there is a possibility that power cannot be supplied from the battery.
摘要翻译：一种移动式超声波诊断装置，包括：电池; 适配器连接检测单元，其检测向所述设备的每个构成元件供电的AC适配器的连接状态; 以及处理确定单元（确定单元），其基于AC适配器的连接状态来确定针对每个构成元件的处理。基于由处理确定单元（确定单元）确定的处理，处理每个构成要素（处理单元和处理单元以外的构成要素），结果，即使在该处理单元是不能从电池供电的可能性。

4. 发明申请

US20160170036A1 RADIATION MEASURING DEVICE 有权
标题翻译：辐射测量装置
公开(公告)号：US20160170036A1
公开(公告)日：2016-06-16
申请号：US14903736
申请日：2014-08-20
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Norio Yoshida , Toshikazu Tanino
IPC分类号： G01T1/169
CPC分类号： G01T1/169 , G01N2201/0221
摘要： In the present invention, a battery box is provided on the lower side of a survey meter body so as to protrude downwardly. Four primary batteries are accommodated inside the battery box with inclined postures. A stepped structure is formed between the front surface of the battery box and the lower surface of the body. The survey meter can be held by a hand while an index finger, or the like, is hooked on the stepped structure. It is also possible to remove the battery box and dispose a plate-like secondary battery in an accommodation space.
摘要翻译：在本发明中，电池盒设置在测仪表主体的下侧以向下突出。四个一次电池容纳在具有倾斜姿势的电池盒内。在电池盒的前表面和主体的下表面之间形成阶梯式结构。当食指或类似物钩在阶梯式结构上时，可以用手握住测量仪表。也可以取出电池盒，并将板状二次电池配置在容纳空间中。

5. 发明申请

US20160120511A1 ULTRASONIC MEDICAL DEVICE 审中-公开
标题翻译：超声医疗器械
公开(公告)号：US20160120511A1
公开(公告)日：2016-05-05
申请号：US14891732
申请日：2014-05-27
申请人： THE UNIVERSITY OF TOKYO , HITACHI ALOKA MEDICAL LTD.)
发明人： Takashi Azuma , Akira Sasaki , Ryosuke Aoyagi , Shu Takagi , Kazunori Itani , Keisuke Fujiwara , Hideki Takeuchi
IPC分类号： A61B8/08 , A61N7/02
CPC分类号： A61B8/485 , A61B8/085 , A61B2018/00589 , A61N7/02 , A61N2007/0052
摘要： A modulation frequency control unit (36) controls a displacement-use transmission unit (34) such that displacement-use ultrasonic beam (EB) is subjected to modulation processing using a relatively high modulation frequency and a relatively low modulation frequency. A displacement measurement unit (24) measures the displacement of a tissue in a treatment area (P) at each of the modulation frequencies, and a coagulation measurement unit (25) measures local coagulation in the treatment area (P) on the basis of the measurement result of the displacement at the relatively high modulation frequency, and measures wide-area coagulation in the treatment area (P) on the basis of the measurement result of the displacement at the relatively low modulation frequency. Consequently, for example, the presence or absence of local coagulation immediately after coagulation has occurred, and the like, can be measured with high accuracy, and further, for example, the size of wide-area coagulation after coagulation has progressed, and the like, can be measured with high accuracy.
摘要翻译：调制频率控制单元（36）控制位移使用传输单元（34），使得位移使用超声波束（EB）使用相对较高的调制频率和相对较低的调制频率进行调制处理。位移测量单元（24）测量每个调制频率处的处理区域（P）中的组织的位移，并且凝固测量单元（25）基于所述调节频率来测量处理区域（P）中的局部凝结在相对较高的调制频率下进行位移的测量结果，并且以相对较低调制频率的位移测量结果为基础测量处理区域（P）中的广域凝结。因此，例如，可以高精度地测量凝固后立即凝固的存在或不存在等，并且例如凝固后的广泛区域凝固的尺寸进行等，可以高精度地测量。

6. 发明申请

US20150351723A1 ULTRASOUND IMAGING DEVICE AND ULTRASOUND IMAGING METHOD 审中-公开
标题翻译：超声成像装置和超声成像方法
公开(公告)号：US20150351723A1
公开(公告)日：2015-12-10
申请号：US14762895
申请日：2014-01-31
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Chizue ISHIHARA , Hiroki TANAKA , Kunio HASHIBA , Hiroshi KURIBARA
IPC分类号： A61B8/08 , A61B8/00 , A61B8/14
CPC分类号： A61B8/5207 , A61B8/145 , A61B8/4483 , A61B8/54 , G01S7/5202 , G01S7/52033 , G01S7/52038 , G01S15/8915 , G01S15/8927
摘要： There is provided a technique for obtaining a high-quality image by extracting only a nonlinear component with high accuracy in ultrasonic imaging using an amplitude modulation method of THI. By removing a fundamental wave component with high accuracy by making the influence of electrical distortion due to analog amplification on the echo signals of ultrasonic waves having different sound pressure levels approximately the same, only the nonlinear component is extracted with high accuracy. For example, the above influence is made to be the same by controlling the amplification factor of an amplification section. In addition, the above influence is made to be the same by restoring the digital data with a filter.
摘要翻译：提供了一种通过使用THI的幅度调制方法在超声成像中仅提取非常高精度的非线性分量来获得高质量图像的技术。通过使模拟放大引起的电变形对具有不同声压级的超声波的回波信号的影响大致相同，通过高精度地移除基波分量，仅提取非线性分量。例如，通过控制放大部的放大系数，使上述影响相同。此外，通过使用滤波器恢复数字数据，使上述影响相同。

7. 发明申请

US20150276685A1 ULTRASONIC PROBE 有权
标题翻译：超声探头
公开(公告)号：US20150276685A1
公开(公告)日：2015-10-01
申请号：US14438795
申请日：2013-10-30
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Takeo Yasuhara , Hidetsugu Katsura , Toru Watanabe
IPC分类号： G01N29/24 , A61B18/04 , A61N7/00 , G01N29/32
CPC分类号： G01N29/24 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/4494 , A61B8/546 , A61B18/04 , A61N7/00 , G01N29/32
摘要： A probe that is inserted into a body cavity, wherein an inner unit (inner assembly) comprises an oscillator unit, an intermediate substrate, an electronic circuit substrate, and a backing member. An exhaust heat sheet is joined to an area at the perimeter of the rear surface of the electronic circuit substrate. The exhaust heat sheet comprises a main body part and a plurality of wings that extend to the outside from the main body part. The plurality of wings include a right wing and a left wing. The wings are inserted into two slits formed in a probe head case (heat radiating shell), and the end parts of the wings are accommodated in and adhered to two recessed sections formed in the outer surface of the probe head case. Thus, heat generated inside the probe head case can be directly transferred to the outer surface of the probe head case.
摘要翻译：插入体腔的探针，其中内部单元（内部组件）包括振荡器单元，中间基板，电子电路基板和背衬构件。排气加热片接合到电子电路基板的后表面周边的区域。排气热板包括从主体部分延伸到外部的主体部分和多个翼部。多个翼包括右翼和左翼。将翅片插入形成在探针头壳体（散热壳体）中的两个狭缝中，并且翼部的端部容纳在形成于探针头壳体的外表面中的两个凹部中并粘附到两个凹部。因此，探头头壳体内产生的热量可以直接传递到探针头壳体的外表面。

8. 发明申请

US20150248750A1 ULTRASOUND DIAGNOSTIC APPARATUS AND ULTRASOUND TWO-DIMENSIONAL CROSS-SECTION IMAGE GENERATION METHOD 有权
标题翻译：超声诊断装置和超声二维交叉图像生成方法
公开(公告)号：US20150248750A1
公开(公告)日：2015-09-03
申请号：US14431603
申请日：2013-09-12
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Takehiro Tsujita
IPC分类号： G06T7/00
CPC分类号： G06T7/00 , A61B5/0059 , A61B8/0883 , A61B8/483 , G01S15/899 , G01S15/8993 , G06T2207/10004 , G06T2207/10132
摘要： An ultrasound diagnostic apparatus includes a light source information setting unit setting light source data indicating a property of a light source irradiated to a cross section region of the object, an optical property setting unit setting a weight coefficient indicating an optical property of cross-section region data including intensity information on the cross section region to the light source, an illuminance slice data creation unit calculating illuminance at positions corresponding to coordinates of a plurality of the cross-section regions based on the light source data and the weight coefficient, and creating illuminance slice data of the plurality of the cross-section regions based on the calculated illuminance, and a composition unit compositing a two-dimensional cross-section image of the object from the plurality of illuminance slice data.
摘要翻译：超声波诊断装置包括：光源信息设定单元，设定指示照射到物体的横截面区域的光源的特性的光源数据;光学特性设定单元，其设定表示横截面积的光学特性的加权系数包括关于光源的横截面区域的强度信息的数据，照度片数据创建单元，基于光源数据和权重系数，计算与多个截面区域的坐标相对应的位置处的照度，以及创建照度基于所计算的照度，所述多个横截面区域的切片数据，以及合成单元，从所述多个照度切片数据合成所述对象的二维截面图像。

9. 发明申请

US20150173720A1 ULTRASONIC DIAGNOSTIC APPARATUS AND ELASTIC EVALUATION METHOD 有权
标题翻译：超声诊断设备和弹性评估方法
公开(公告)号：US20150173720A1
公开(公告)日：2015-06-25
申请号：US14635159
申请日：2015-03-02
申请人： Hitachi Aloka Medical, Ltd.
发明人： Hideki YOSHIKAWA
IPC分类号： A61B8/08 , A61B8/00
CPC分类号： A61B8/485 , A61B8/463 , A61B8/469 , A61B8/488 , A61B8/5207 , A61B8/5223 , A61B8/5269 , G01S7/52042 , G01S7/52063 , G01S7/52071 , G01S7/52074
摘要： An ultrasonic diagnostic apparatus and a method having a highly-reliable elastic evaluation unit for tissues. The invention includes a signal processing unit that processes received data obtained after ultrasonic waves are transmitted and received to/from an inspection target through a probe. An ROI detection unit of the processing unit obtains a distance index indicating a region proper for an elastic evaluation based on brightness distribution of the received data obtained by transmitting and receiving first ultrasonic waves to/from the probe, and sets an ROI based on the distance index. Then, second ultrasonic waves are transmitted to the ROI to generate shear waves. An elastic evaluation unit calculates a shear wave velocity based on received data obtained by transmitting and receiving third ultrasonic waves in the ROI, and outputs the shear wave velocity and an elastic evaluation value of the ROI as a reliability index.
摘要翻译：一种超声波诊断装置和具有用于组织的高可靠性弹性评价单元的方法。本发明包括信号处理单元，该信号处理单元处理通过探头将超声波发送和接收到检查对象之后获得的接收数据。处理单元的ROI检测单元基于通过从探头发送和接收第一超声波获得的接收数据的亮度分布，获得指示用于弹性评估的适当区域的距离指标，并且基于距离指数。然后，第二超声波被传送到ROI以产生剪切波。弹性评估单元基于通过在ROI中发送和接收第三超声波获得的接收数据来计算剪切波速度，并输出剪切波速度和ROI的弹性评估值作为可靠性指标。

10. 发明申请

US20150173718A1 ULTRASONIC DIAGNOSIS DEVICE AND TRANSMISSION/RECEPTION METHOD 有权
标题翻译：超声诊断装置及传输/接收方法
公开(公告)号：US20150173718A1
公开(公告)日：2015-06-25
申请号：US14413174
申请日：2014-01-29
申请人： HITACHI ALOKA MEDICAL, LTD.
发明人： Marie Tabaru , Hideki Yoshikawa , Rei Asami , Kunio Hashiba , Hiroshi Masuzawa
IPC分类号： A61B8/08 , A61B8/00
CPC分类号： A61B8/485 , A61B8/08 , A61B8/085 , A61B8/463 , A61B8/5207 , A61B8/5223 , G01S7/52042
摘要： There is provided an ultrasonic diagnostic apparatus capable of measuring hardness information of a subject with high time resolution and spatial resolution.The apparatus is provided with a ultrasonic probe 1 and a displacement generation unit 10 configured to displace an inside of a subject and is configured to transmit an ultrasonic beam for displacement detection to a plurality of detection positions of the subject from the ultrasonic probe 1, and to detect a shear wave velocity based on the displacement at the plurality of detection positions in a control unit 3 by using a reflection signal detected in a detection unit 20, thereby outputting hardness information of the subject. The ultrasonic beam for displacement detection is transmitted to one of the plurality of detection positions. A waveform analysis unit 26 of the control unit 3 is configured to perform a change control of analyzing a shear wave resulting from the displacement to thus transmit the ultrasonic beam for displacement detection to another position of the plurality of detection positions. Thereby, it is possible to measure the shear wave velocity with high time resolution and spatial resolution, so that it is possible to obtain the hardness information of the subject with high precision.
摘要翻译：提供了能够以高时间分辨率和空间分辨率来测量被检体的硬度信息的超声波诊断装置。该装置设置有超声波探头1和位移产生单元10，其被配置为使被检体的内部移位，并且被配置为从超声波探头1向被检体的多个检测位置发送用于位移检测的超声波束，以及通过使用在检测单元20中检测到的反射信号，基于控制单元3中的多个检测位置处的位移检测剪切波速度，从而输出被检体的硬度信息。用于位移检测的超声波束被发送到多个检测位置中的一个。控制单元3的波形分析单元26被配置为执行分析由位移产生的剪切波的变化控制，从而将用于位移检测的超声波束发送到多个检测位置的另一位置。由此，可以以高时间分辨率和空间分辨率测量剪切波速度，从而可以高精度地获得被检体的硬度信息。

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