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    • 3. 发明授权
    • Method and apparatus of background suppression in MR imaging using spin locking
    • 使用自旋锁定的MR成像中背景抑制的方法和装置
    • US07064545B2
    • 2006-06-20
    • US10711169
    • 2004-08-30
    • Gregory G. ZaharchukJean H. Brittain
    • Gregory G. ZaharchukJean H. Brittain
    • G01V3/00
    • G01R33/563
    • The present invention is directed to a method and system of tissue or background suppression for the acquisition of image data from blood flow or tissue perfusion. Background suppression with minimal effects upon inflowing spins is achieved through a series of spin locking low level RF pulses that cause adiabatic demagnetization of tissue with a relaxation time T1-rho that is intermediate between T1 and T2 relaxation times. In this regard, the effective transverse magnetization of static tissue resulting from the application of a series of low level RF pulses is reduced and, with the spin locking, longitudinal magnetization regrowth is minimized. As such, inflowing spins to an imaging volume may be directly imaged with significant background tissue suppression. The present invention is particularly applicable to time-of-flight MRA and MR perfusion imaging.
    • 本发明涉及用于从血流或组织灌注获取图像数据的组织或背景抑制的方法和系统。 通过一系列自旋锁定低水平射频脉冲来实现对流入旋转影响最小的背景抑制,其使得在T1和T2弛豫时间之间的弛豫时间T1-rho导致组织绝热退磁。 在这方面,由于施加一系列低电平RF脉冲导致的静电组织的有效横向磁化强度降低,并且随着自旋锁定,纵向磁化强度再生长被最小化。 这样,流入成像体积的流动可以直接用显着的背景组织抑制成像。 本发明特别适用于飞行时间MRA和MR灌注成像。