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1. 发明申请

US20070073280A1 End-fire guided ablation 审中-公开
标题翻译：终火引导消融
公开(公告)号：US20070073280A1
公开(公告)日：2007-03-29
申请号：US11385316
申请日：2006-03-20
申请人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
发明人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
IPC分类号： A61B18/18
CPC分类号： A61B18/24 , A61B90/11 , A61B2018/00023 , A61B2018/00196 , A61B2018/2288
摘要： An apparatus for forming a lesion in tissue along a desired ablation path includes a guide member having a tissue-opposing surface for placement against a heart surface. A guide carriage is sized to be received within the guide member and moveable therein along a longitudinal axis. The carriage is configured to receive an optical fiber extending substantially axially within the carriage and bend the fiber for a discharge tip of the fiber to aim through a bottom wall of the guide member. The carriage is further configured to bend the fiber toward said discharge tip with a curved portion subject to mechanical stress and a straight portion at the fiber discharge tip. The straight portion is selected to have a length to dissipate thermal stress arising from reflectance of light from the tissue back into the discharge tip.
摘要翻译：用于沿着期望的消融路径在组织中形成病变的装置包括具有用于放置在心脏表面上的组织相对表面的引导构件。引导托架的尺寸被设计成被容纳在引导构件内并沿着纵向轴线在其中可移动。滑架被构造成接收在滑架内基本上轴向延伸的光纤，并且弯曲光纤以使纤维的放电尖端瞄准穿过引导构件的底壁。托架进一步构造成使纤维朝着所述排出端弯曲，具有受到机械应力的弯曲部分和在纤维排出端部处的直线部分。直线部分被选择为具有消散由来自组织的光的反射率引起的放电尖端的热应力的长度。

2. 发明申请

US20070168020A1 Bifurcated stent and delivery system 失效
标题翻译：分叉支架和分娩系统
公开(公告)号：US20070168020A1
公开(公告)日：2007-07-19
申请号：US11726144
申请日：2007-03-21
申请人： Gregory Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava Chernomordik , William Mers Kelly , William Reuss , Simon Furnish , Michael Wilson , Hacene Bouadi , John Muskivitch , Matthew Pease , David Rahdert , Travis Rowe , Gregory Ruhf , Brandon Walsh , Claude Vidal , Thomas Banks , Russ Redmond
发明人： Gregory Brucker , Enrique Malaret , Todd Hall , David Byrd , Gerald Hubbs , Gregory Furnish , Josh Barber , Indaka Gunasekara , Benjamin Morris , Valerie Futral , Sava Chernomordik , William Mers Kelly , William Reuss , Simon Furnish , Michael Wilson , Hacene Bouadi , John Muskivitch , Matthew Pease , David Rahdert , Travis Rowe , Gregory Ruhf , Brandon Walsh , Claude Vidal , Thomas Banks , Russ Redmond
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/954 , A61F2/958 , A61F2/966 , A61F2/97 , A61F2002/061 , A61F2002/821 , A61F2002/9583 , A61F2250/006
摘要： A bifurcated stent includes a first stent section and a second stent section. The first stent section is balloon expandable, has an unexpanded configuration, an expanded configuration, and a tubular wall defining a secondary opening. The secondary stent section is self-expanding and an end of the secondary stent section is engaged to a portion of the tubular wall of the primary stent section defining the secondary opening. The secondary stent section has an unexpanded configuration with a first length and an expanded configuration with a second length where the first length is less than the second length. The secondary stent section is expanded to the expanded configuration after the primary stent section is expanded to the expanded configuration. The secondary stent section forms a portion of the tubular wall of the primary stent section in the unexpanded configuration.
摘要翻译：分支支架包括第一支架部分和第二支架部分。第一支架部分是球囊可膨胀的，具有未膨胀的构造，膨胀的构型和限定次级开口的管状壁。辅助支架部分是自膨胀的，并且次级支架部分的端部接合到限定第二开口的主支架部分的管状壁的一部分。次级支架部分具有第一长度和第二长度的膨胀构造的未膨胀构型，其中第一长度小于第二长度。在将主支架部分扩展到扩张构型之后，将二次支架部分扩大到扩张构型。辅助支架部分以未展开的构型形成主支架部分的管状壁的一部分。

3. 发明申请

US20070073281A1 Guided ablation with motion control 审中-公开
标题翻译：引导消融与运动控制
公开(公告)号：US20070073281A1
公开(公告)日：2007-03-29
申请号：US11385358
申请日：2006-03-20
申请人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
发明人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
IPC分类号： A61B18/18
CPC分类号： A61B18/24 , A61B18/02 , A61B18/1492 , A61B90/11 , A61B2017/00243 , A61B2018/00196 , A61B2018/2288
摘要： An apparatus for forming a lesion in tissue along a desired ablation path includes a guide member having a tissue-opposing surface for placement against a heart surface. A guide carriage is sized to be received within the guide member and moveable therein along a longitudinal axis. A flexible tubular member extends from a proximal end of said carriage and through a length of the guide member with the tubular member adapted to move the carriage within the guide member upon application of a force to the tubular member. A system urges the carriage to move in a path along an axis of the guide member by amount substantially identical to a displacement of a force application location on the flexible tubular member.
摘要翻译：用于沿着期望的消融路径在组织中形成病变的装置包括具有用于放置在心脏表面上的组织相对表面的引导构件。引导托架的尺寸被设计成被容纳在引导构件内并沿着纵向轴线在其中可移动。柔性管状构件从所述托架的近端延伸并且穿过引导构件的长度，其中管状构件适于在对管状构件施加力时将托架移动到引导构件内。系统促使滑架沿着引导构件的轴线的路径移动，其量基本上与柔性管状构件上的施力位置的位移相同。

4. 发明申请

US20070073277A1 Controlled guided ablation treatment 审中-公开
标题翻译：受控引导消融治疗
公开(公告)号：US20070073277A1
公开(公告)日：2007-03-29
申请号：US11385317
申请日：2006-03-20
申请人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
发明人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
IPC分类号： A61B18/18
CPC分类号： A61B18/22 , A61B5/053 , A61B5/0538 , A61B5/117 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00084 , A61B2017/00115 , A61B2017/00243 , A61B2017/00247 , A61B2017/0243 , A61B2017/306 , A61B2017/3488 , A61B2018/00011 , A61B2018/00196 , A61B2018/00392 , A61B2018/00577 , A61B2018/00636 , A61B2018/2288 , A61B2090/064
摘要： An apparatus for forming a lesion in tissue along a desired ablation path includes a guide member having a tissue-opposing surface for placement against a heart surface. A guide carriage is sized to be received within the guide member and moveable along a longitudinal axis of the guide member. A tubular member extends from a proximal end of the carriage and out a proximal end of the guide member. An ablation element is carried in the carriage for movement. The ablation member is connected to a source of ablation energy through the tubular member. A sensor is provided for sensing a safety condition. The sensor is connected to a monitor external the guide member.
摘要翻译：用于沿着期望的消融路径在组织中形成病变的装置包括具有用于放置在心脏表面上的组织相对表面的引导构件。导向架的尺寸被设计成被容纳在引导构件内并且可以沿着引导构件的纵向轴线移动。管状构件从托架的近端延伸并且从引导构件的近端延伸出来。在滑架中携带消融元件用于移动。消融构件通过管状构件连接到消融能量源。提供传感器用于感测安全条件。传感器连接到引导构件外部的监视器。

5. 发明申请

US20060285793A1 Side-firing laser 失效
公开(公告)号：US20060285793A1
公开(公告)日：2006-12-21
申请号：US11155348
申请日：2005-06-17
申请人： John Brekke , Gregory Brucker
发明人： John Brekke , Gregory Brucker
IPC分类号： G02B6/42 , G02B6/26 , G02B6/02
CPC分类号： A61B18/24 , A61B2018/2272 , G02B6/241 , G02B6/262
摘要： An apparatus for transmitting laser light and redirecting the light laterally relative to an axis of the apparatus includes an optical fiber having both a core and a cladding surrounding the core. The optical fiber terminates at a distal tip having a surface inclined relative to the axis of the optical fiber. A tubular member surrounds the optical fiber at its distal end. The distal end of the optical fiber has a portion opposing the tubular member for being united to the tubular member. The distal portion is joined to the tubular member by an intermediate material selected to have an index of refraction matching that of the core and the tubular member.

6. 发明申请

US20050209589A1 Assessment of lesion transmurality 失效
标题翻译：病变透壁性评估
公开(公告)号：US20050209589A1
公开(公告)日：2005-09-22
申请号：US11133900
申请日：2005-05-19
申请人： Adam Berman , Gregory Brucker , Robert Svenson
发明人： Adam Berman , Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00029 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-opposing surface for placement against a heart surface. An ablation member is coupled to the guide member to move in a longitudinal path relative to the guide member. The ablation member has an ablation element for directing ablation energy in an emitting direction away from the tissue-opposing surface. The guide member may be flexible to adjust a shape of the guide member for the longitudinal path to approximate the desired ablation path while maintaining the tissue-opposing surface against the heart surface. In one embodiment, the ablation member includes at least one radiation-emitting member disposed to travel in the longitudinal pathway. Transmurality can be assessed to approximate a location of non-transmurality in a formed lesion.
摘要翻译：一种用于原位处理身体组织（例如，心脏的心房组织以治疗）心房颤动的方法和装置包括将病变形成工具定位在心脏表面上。损伤形成工具包括具有用于放置在心脏表面上的组织相对表面的引导构件。消融构件联接到引导构件以相对于引导构件在纵向路径中移动。消融构件具有消融元件，用于将发射方向上的消融能量远离组织相对表面。引导构件可以是柔性的，以调节用于纵向路径的引导构件的形状以接近所需的消融路径，同时将组织相对表面保持抵靠心脏表面。在一个实施例中，消融构件包括设置成在纵向通路中行进的至少一个辐射发射构件。透视性可以被评估以在形成的病变中近似非透壁的位置。

7. 发明申请

US20050159734A1 Atraumatic laser tip for atrial fibrillation treatment 失效
标题翻译：无创激光尖端用于房颤治疗
公开(公告)号：US20050159734A1
公开(公告)日：2005-07-21
申请号：US11080855
申请日：2005-03-15
申请人： Gregory Brucker , Robert Svenson
发明人： Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating in situ biologic tissue include identifying a patient with a condition susceptible to treatment by forming a lesion in the tissue and accessing a surface of the tissue. A lesion formation tool is positioned against the accessed surface. The tool includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip for discharge of light energy from the fiber tip. The wavelength is selected for the light energy to penetrate a full thickness of the tissue to form a volume of necrosed tissue through the thickness of the tissue. The tool further includes a guide tip coupled to the fiber tip. The guide tip is adapted to have a discharge bore aligned with the fiber tip to define an unobstructed light pathway from the fiber tip to the tissue surface. The guide tip is further adapted to be placed against the tissue surface with the guide tip slidable along the tissue surface in atraumatic sliding engagement with the discharge bore opposing the issue surface. The lesion formation tool is manipulated to draw the guide tip over the tissue surface in a pathway while maintaining the discharge bore opposing the tissue surface to form a transmural lesion in the tissue extending a length of the pathway.
摘要翻译：用于治疗原位生物组织的方法和装置包括通过在组织中形成病变并进入组织的表面来识别具有易于治疗的病症的患者。病变形成工具抵靠所访问的表面定位。该工具包括用于将所选波长的相干波形引导到光纤尖端的光纤，用于从光纤尖端排出光能。选择波长以使光能穿透组织的整个厚度，以通过组织的厚度形成一定数量的坏死组织。该工具还包括连接到纤维尖端的引导尖端。引导尖端适于具有与纤维末端对准的排出孔，以限定从纤维尖端到组织表面的无阻碍的光路径。引导尖端进一步适于被放置在组织表面上，其中引导尖端可沿组织表面滑动，与与检查表面相对的排出孔无创伤滑动接合。操纵损伤形成工具以将引导尖端在通道中的组织表面上拉伸，同时保持排出孔与组织表面相对，以在组织中形成延伸通路长度的跨壁损伤。

8. 发明申请

US20050143722A1 Laser-based maze procedure for atrial fibrillation 失效
标题翻译：用于心房颤动的基于激光的迷宫程序
公开(公告)号：US20050143722A1
公开(公告)日：2005-06-30
申请号：US11067131
申请日：2005-02-25
申请人： Gregory Brucker , Robert Svenson
发明人： Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating in situ biologic tissue include identifying a patient with a condition susceptible to treatment by forming a lesion in the tissue and accessing a surface of the tissue. A lesion formation tool is positioned against the accessed surface. The tool includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip for discharge of light energy from the fiber tip. The wavelength is selected for the light energy to penetrate a full thickness of the tissue to form a volume of necrosed tissue through the thickness of the tissue. The tool further includes a guide tip coupled to the fiber tip. The guide tip is adapted to have a discharge bore aligned with the fiber tip to define an unobstructed light pathway from the fiber tip to the tissue surface. The guide tip is further adapted to be placed against the tissue surface with the guide tip slidable along the tissue surface in atraumatic sliding engagement with the discharge bore opposing the tissue surface. The lesion formation tool is manipulated to draw the guide tip over the tissue surface in a pathway while maintaining the discharge bore opposing the tissue surface to form a transmural lesion in the tissue extending a length of the pathway.
摘要翻译：用于治疗原位生物组织的方法和装置包括通过在组织中形成病变并进入组织的表面来识别具有易于治疗的病症的患者。病变形成工具抵靠所访问的表面定位。该工具包括用于将所选波长的相干波形引导到光纤尖端的光纤，用于从光纤尖端排出光能。选择波长以使光能穿透组织的整个厚度，以通过组织的厚度形成一定数量的坏死组织。该工具还包括连接到纤维尖端的引导尖端。引导尖端适于具有与纤维末端对准的排出孔，以限定从纤维尖端到组织表面的无阻碍的光路径。引导尖端进一步适于放置在组织表面上，其中引导尖端沿组织表面滑动，与组织表面相对的排出孔以无创的方式滑动接合。操纵损伤形成工具以将引导尖端在通道中的组织表面上拉伸，同时保持排出孔与组织表面相对，以在组织中形成延伸通路长度的跨壁损伤。

9. 发明授权

US06425894B1 Ablation catheter with electrode temperature monitoring 有权
标题翻译：消融导管与电极温度监测
公开(公告)号：US06425894B1
公开(公告)日：2002-07-30
申请号：US09614362
申请日：2000-07-12
申请人： Gregory Brucker , William Penny
发明人： Gregory Brucker , William Penny
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B18/14 , A61B2018/00214 , A61B2018/00654 , A61B2018/00797 , A61B2018/00821 , A61B2018/00898 , A61B2018/124
摘要： An ablation catheter is provided which comprises an elongated catheter body, a plurality of electrodes, and a thermal monitoring circuit. The thermal monitoring circuit is comprised of a plurality of thermocouples joined in series. The thermocouples thermoconductively coupled to the electrodes. The thermal monitoring circuit will require only two wires to travel through the elongated catheter body in order to monitor a plurality of electrodes.
摘要翻译：提供消融导管，其包括细长的导管主体，多个电极和热监测电路。热监测电路由串联连接的多个热电偶组成。热电偶热电耦合到电极。热监测电路将仅需要两条电线穿过细长的导管体，以便监测多个电极。

10. 发明申请

US20060285798A1 Bent side-firing laser 审中-公开
标题翻译：弯曲侧发激光
公开(公告)号：US20060285798A1
公开(公告)日：2006-12-21
申请号：US11495023
申请日：2006-07-28
申请人： John Brekke , Gregory Brucker
发明人： John Brekke , Gregory Brucker
IPC分类号： G02B6/42 , G02B6/02 , G02B6/26
CPC分类号： G02B6/262 , A61B18/24 , A61B2018/2272 , G02B6/241
摘要： An apparatus for transmitting laser light and redirecting the light laterally relative to an axis of the apparatus includes an optical fiber having a core and a cladding surrounding the core. The core terminates at a core end. The cladding terminates at a cladding end spaced from the core end to expose an exposed length of the core. A tubular member surrounds at least a distal portion of the fiber and has a closed distal end. The exposed length of the core is bent for the core end to oppose a side of said tubular member. The core end is bonded to the side of the tubular member. A seal creates a sealed volume of the tubular member surrounding said exposed length. The volume may contain a vacuum or a gas such as air.
摘要翻译：用于传输激光并相对于设备的轴线横向地重定向光的装置包括具有芯和围绕芯的包层的光纤。核心终止于核心。包层终止于与芯部端部间隔开的包层端部，以露出芯部的暴露长度。管状构件围绕纤维的至少远端部分并且具有封闭的远端。芯的暴露长度被弯曲以使芯端相对于所述管状构件的一侧。芯端结合到管状构件的侧面。密封件形成围绕所述暴露长度的管状构件的密封体积。体积可以包含真空或诸如空气的气体。

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