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1. 发明授权

US08563912B2 Microscope having focus-holding unit 有权
标题翻译：显微镜具有聚焦保持单元
公开(公告)号：US08563912B2
公开(公告)日：2013-10-22
申请号：US12937970
申请日：2009-04-04
申请人： Reiner Mitzkus , Eugen Wehner , Stefan Steinborn , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
发明人： Reiner Mitzkus , Eugen Wehner , Stefan Steinborn , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
IPC分类号： G02B27/40
CPC分类号： G02B21/241
摘要： The invention relates to a microscope having a stage for supporting a sample to be examined, a recording sensor, an imaging optic for imaging the sample onto the recording sensor, a moving unit by means of which the distance between the stage and the imaging optic can be changed, a control unit for controlling an image recording of the sample and a focus-holding unit for maintaining a prescribed focal position for image recording of the sample at temporal intervals, wherein the focus-holding device comprises at least one hardware element and one software module, wherein the focus-holding unit is fully integrated in the control unit, on both the hardware and software sides.
摘要翻译：本发明涉及一种显微镜，其具有用于支撑待检查样本的台，记录传感器，用于将样本成像到记录传感器上的成像光学元件，移动单元，通过该移动单元，台与成像光学元件之间的距离改变控制单元，用于控制样本的图像记录;以及聚焦保持单元，用于维持用于以时间间隔对样本进行图像记录的规定焦点位置，其中聚焦保持装置包括至少一个硬件元件和一个软件模块，其中聚焦保持单元在硬件和软件两侧完全集成在控制单元中。

2. 发明申请

US20110043905A1 MICROSCOPE HAVING FOCUS-HOLDING UNIT 有权
标题翻译：具有聚焦控制单元的显微镜
公开(公告)号：US20110043905A1
公开(公告)日：2011-02-24
申请号：US12937970
申请日：2009-04-04
申请人： Reiner Mitzkus , Eugen Wehner , Stefan Steinborn , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
发明人： Reiner Mitzkus , Eugen Wehner , Stefan Steinborn , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
IPC分类号： G02B21/24
CPC分类号： G02B21/241
摘要： The invention relates to a microscope having a stage for supporting a sample to be examined, a recording sensor, an imaging optic for imaging the sample onto the recording sensor, a moving unit by means of which the distance between the stage and the imaging optic can be changed, a control unit for controlling an image recording of the sample and a focus-holding unit for maintaining a prescribed focal position for image recording of the sample at temporal intervals, wherein the focus-holding device comprises at least one hardware element and one software module, wherein the focus-holding unit is fully integrated in the control unit, on both the hardware and software sides.
摘要翻译：本发明涉及一种显微镜，其具有用于支撑待检查样本的台，记录传感器，用于将样本成像到记录传感器上的成像光学元件，移动单元，通过该移动单元，台与成像光学元件之间的距离改变控制单元，用于控制样本的图像记录;以及聚焦保持单元，用于维持用于以时间间隔对样本进行图像记录的规定焦点位置，其中聚焦保持装置包括至少一个硬件元件和一个软件模块，其中聚焦保持单元在硬件和软件两侧完全集成在控制单元中。

3. 发明授权

US09128296B2 Microscope with retain focus control 有权
标题翻译：显微镜保留对焦控制
公开(公告)号：US09128296B2
公开(公告)日：2015-09-08
申请号：US12937965
申请日：2009-04-04
申请人： Stefan Steinborn , Eugen Wehner , Reiner Mitzkus , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
发明人： Stefan Steinborn , Eugen Wehner , Reiner Mitzkus , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
IPC分类号： G02B27/64 , G02B21/24 , G03B13/34 , G01B11/22 , G03B13/32 , G01B11/28 , G06K9/00 , G05B11/12 , G05B11/06 , G05B11/10 , G03B13/36 , G02B21/36
CPC分类号： G02B21/241 , G01B11/22 , G01B11/28 , G01B11/285 , G02B21/367 , G03B13/32 , G03B13/34 , G03B13/36 , G05B11/06 , G05B11/10 , G05B11/12 , G06K9/00127
摘要： A microscope including an imaging optical unit, a sample stage for supporting a sample to be examined, a movement unit, by which the distance between sample stage and imaging optical unit can be altered, a focus measuring unit, which measures the present focus position and outputs a focus measurement signal, a control unit for maintaining a predetermined focus position for examinations of the sample that are separated from one another in time. The control unit receives the focus measurement signal and derives a deviation of the present focus position from the predetermined focus position. Dependent on the deviation derived the movement unit, changes the distance between sample stage and imaging optical unit so that the predetermined focus position is maintained. The control unit drives the movement unit (9) for maintaining the predetermined focus position only before and/or after at least one of the examinations, but never during the examinations.
摘要翻译：显微镜，包括成像光学单元，用于支撑待检测样品的样品台，可以改变样品台和成像光学单元之间的距离的移动单元，测量当前聚焦位置的聚焦测量单元，输出焦点测量信号，用于维持用于在时间上彼此分离的样本的检查的预定焦点位置的控制单元。控制单元接收聚焦测量信号并且导出当前聚焦位置与预定聚焦位置的偏差。取决于移动单元的偏差，改变样本台与成像光学单元之间的距离，从而保持预定的对焦位置。控制单元驱动运动单元（9），用于仅在检查中的至少一个之前和/或之后维持预定的对焦位置，但从不在检查期间。

4. 发明授权

US09036254B2 Apparatus and method for transmitted light illumination for light microscopes and microscope system 有权
标题翻译：用于光学显微镜和显微镜系统的透射光照明的装置和方法
公开(公告)号：US09036254B2
公开(公告)日：2015-05-19
申请号：US13978621
申请日：2012-08-16
申请人： Detlef Hein , Juergen Fechti , Gleb Milinovici
发明人： Detlef Hein , Juergen Fechti , Gleb Milinovici
IPC分类号： G02B21/06 , G02B21/08
CPC分类号： G02B21/06 , G02B21/086
摘要： An apparatus for transmitted light illumination for light microscopes A diaphragm edge may be variably positioned in the direction of the optical axis, wherein a position of the diaphragm edge in the direction of the optical axis can be varied irrespectively of a position of the diaphragm edge transversely to the optical axis. A separate sample support table may be mounted on a housing. The housing has a passage opening, through which the diaphragm edge can be moved in the direction of the optical axis. A holding device is formed in the region of the passage opening of the housing or on a separate sample support table and a control device is present which is adapted to position the diaphragm edge in dependence at least upon a determined presence of a sample support table.
摘要翻译：用于光学显微镜的透射光照明的装置光阑边缘可以沿光轴的方向可变地定位，其中光阑边缘在光轴方向上的位置可以随着光阑边缘横向的位置而变化到光轴。单独的样品支撑台可以安装在壳体上。壳体具有通道开口，光阑边缘可以通过该通道开口沿光轴方向移动。保持装置形成在壳体的通道开口的区域中或在单独的样品支撑台上，并且存在控制装置，该控制装置适于至少根据确定的样品支撑台的存在来定位隔膜边缘。

5. 发明申请

US20140192408A1 Apparatus and method for transmitted light illumination for light microscopes and microscope system 有权
公开(公告)号：US20140192408A1
公开(公告)日：2014-07-10
申请号：US13978621
申请日：2012-08-16
申请人： Detlef Hein , Juergen Fechti , Gleb Milinovici
发明人： Detlef Hein , Juergen Fechti , Gleb Milinovici
IPC分类号： G02B21/06
CPC分类号： G02B21/06 , G02B21/086
摘要： The invention relates to an apparatus for transmitted light illumination for light microscopes, in particular stereo microscopes or macroscopes, having changing effective entrance pupil of an objective. The apparatus has a light source for emitting an illuminating light beam, a housing, in which the light source is arranged, a holding device for holding a sample to be examined and at least one diaphragm edge for trimming the illuminating light beam, wherein the diaphragm edge extends transversely to an optical axis of a light microscope, which can be positioned in an operating state on the device for transmitted light illumination, and wherein a beam path of the illuminating light between the diaphragm edge and the sample held by the holding device is free from adjustable beam focussing components. The apparatus is characterised according to the invention in that in order to adapt the beam path of the illuminating light to the effective entrance pupil of the objective, means are provided for variable positioning of the diaphragm edge in the direction of the optical axis, wherein a position of the diaphragm edge in the direction of the optical axis can be varied irrespectively of a position of the diaphragm edge transversely to the optical axis, assembly means are provided on the housing for mounting a separate sample support able, means for determining the presence of a sample support table are present, the housing has a passage opening, through which the diaphragm edge can be moved in the direction of the optical axis, the holding device is formed in the region of the passage opening of the housing or on a separate sample support table and a control device is present which is adapted to position the diaphragm edge in dependence at least upon a determined presence of a sample support table. The invention also relates to a method for transmitted light illumination for a light microscope and a microscope system.

6. 发明申请

US20110051232A1 MICROSCOPE WITH RETAIN FOCUS CONTROL 有权
标题翻译：具有保留焦点控制的MICROSCOPE
公开(公告)号：US20110051232A1
公开(公告)日：2011-03-03
申请号：US12937965
申请日：2009-04-04
申请人： Stefan Steinborn , Eugen Wehner , Reiner Mitzkus , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
发明人： Stefan Steinborn , Eugen Wehner , Reiner Mitzkus , Gleb Milinovici , Steffen Leidenbach , Peter Westphal
IPC分类号： G02B21/26 , G02B21/00
CPC分类号： G02B21/241 , G01B11/22 , G01B11/28 , G01B11/285 , G02B21/367 , G03B13/32 , G03B13/34 , G03B13/36 , G05B11/06 , G05B11/10 , G05B11/12 , G06K9/00127
摘要： A microscope including an imaging optical unit, a sample stage for supporting a sample to be examined, a movement unit, by which the distance between sample stage and imaging optical unit can be altered, a focus measuring unit, which measures the present focus position and outputs a focus measurement signal, a control unit for maintaining a predetermined focus position for examinations of the sample that are separated from one another in time. The control unit receives the focus measurement signal and derives a deviation of the present focus position from the predetermined focus position. Dependent on the deviation derived the movement unit, changes the distance between sample stage and imaging optical unit so that the predetermined focus position is maintained. The control unit drives the movement unit (9) for maintaining the predetermined focus position only before and/or after at least one of the examinations, but never during the examinations.
摘要翻译：显微镜，包括成像光学单元，用于支撑待检测样品的样品台，可以改变样品台和成像光学单元之间的距离的移动单元，测量当前聚焦位置的聚焦测量单元，输出焦点测量信号，用于维持用于在时间上彼此分离的样本的检查的预定焦点位置的控制单元。控制单元接收聚焦测量信号并且导出当前聚焦位置与预定聚焦位置的偏差。取决于移动单元的偏差，改变样本台与成像光学单元之间的距离，从而保持预定的对焦位置。控制单元驱动运动单元（9），用于仅在检查中的至少一个之前和/或之后维持预定的对焦位置，但从不在检查期间。

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