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    • 2. 发明授权
    • Diastereomers of 1-(isopropoxycarbonyloxy) ethyl 3-cephem 4-carboxylate
    • 1-(异丙氧基羰基氧基)乙基3-头孢烯-4-羧酸酯的非对映异构体
    • US5550232A
    • 1996-08-27
    • US447229
    • 1995-05-22
    • Gerd FischerElisabeth DefossaUwe GerlachRolf H orleinNorbert KrassRudolf LattrellUlrich StacheTheodor WollmannDieter Isert
    • Gerd FischerElisabeth DefossaUwe GerlachRolf H orleinNorbert KrassRudolf LattrellUlrich StacheTheodor WollmannDieter Isert
    • A61K31/545A61K31/546A61P31/04C07D501/00C07D501/06C07D501/34C07D501/56C07D501/14
    • C07D501/00
    • Enterally absorbable diastereomers of 1-(isopropoxycarbonyloxy)ethyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(methoxymethyl)-3-cephem-4-carboxylate of the formula I ##STR1## and their physiologically acceptable salts and also diastereomerically pure salts of the compounds of the formula II ##STR2## where HX is a mono- or polybasic acid and where X is an inorganic or organic physiologically acceptable anion, and a process for the preparation of these compounds of the formula I or II, which comprises first precipitating the more sparingly soluble diastereomer of the formula IV in the mixing together of 1 equivalent of a solution of the diastereomer mixture of the formula III with 0.2-2 equivalents of a solution of the acid component HY and separating it off by filtration, then precipitating the more readily soluble diastereomer of the formula IV from the filtration solution, it being possible for the acid component HY to be identical or different in the consecutive partial steps and any desired sequence of addition of different acid components HY being possible, and optionally further purifying the obtained salts by crystallization, are described.
    • 1-(异丙氧羰基氧基)乙基(6R,7R)-7- [2-(2-氨基噻唑-4-基)-2-(Z) - (甲氧基亚氨基)乙酰氨基] -3-(甲氧基甲基)-3 式I的化合物 - 头孢烯-4-羧酸酯及其生理学上可接受的盐以及式II化合物的非对映体纯盐,其中HX是单或多元酸,其中X是无机或有机的 生理学上可接受的阴离子,以及制备这些式I或II化合物的方法,其包括首先将式IV的较微溶的非对映体沉淀在1当量的式(I)的非对映体混合物的溶液中, III与0.2-2当量的酸组分HY的溶液并通过过滤分离,然后从过滤溶液中沉淀出更容易溶解的式IV的非对映异构体,酸组分HY可能相同或不同 在一起 描述了部分步骤和任何期望的不同酸组分HY的加入顺序是可能的,并且任选地通过结晶进一步纯化得到的盐。
    • 7. 发明授权
    • Neck rest for the seat of an automobile
    • 颈部休息一个汽车的座位
    • US07048336B2
    • 2006-05-23
    • US10889033
    • 2004-07-13
    • Gerald MawbeyGerd FischerRoland Och
    • Gerald MawbeyGerd FischerRoland Och
    • A47C7/36
    • B60N2/806B60N2/888
    • A neck rest includes first and second supports having first and second positions where the supports are at approximately the same level and the second support is elevated relative to the first support, respectively. A first spring is supported by the first support and rotatably connected to the second support to bias the second support into the second position. A movable locking element biased by a second spring on the first support automatically blocks the second support in the second position. A locking element is movably supported by the first support and cooperates with a projection of the second support to lock the second support in the first position. A releasing element is movably supported by the first support and releases the locking element when actuated. A supporting member is located between the supports in the second position for transferring shock forces from the second support to the first support.
    • 颈部支架包括具有第一和第二位置的第一和第二支撑件,其中支撑件处于大致相同的水平面,并且第二支撑件分别相对于第一支撑件升高。 第一弹簧由第一支撑件支撑并且可旋转地连接到第二支撑件,以将第二支撑件偏压到第二位置。 由第二弹簧偏置在第一支架上的可移动锁定元件在第二位置自动地阻挡第二支撑件。 锁定元件由第一支撑件可移动地支撑并与第二支撑件的突起配合,以将第二支撑件锁定在第一位置。 释放元件由第一支撑件可移动地支撑并且当致动时释放锁定元件。 支撑构件位于第二位置的支撑件之间,用于将冲击力从第二支撑件传递到第一支撑件。
    • 8. 发明申请
    • Neck rest for the seat of an automobile
    • 颈部休息一个汽车的座位
    • US20050046262A1
    • 2005-03-03
    • US10889033
    • 2004-07-13
    • Gerald MawbeyGerd FischerRoland Och
    • Gerald MawbeyGerd FischerRoland Och
    • B60N2/48A47C1/10B60R22/28
    • B60N2/806B60N2/888
    • A neck rest includes first and second supports having first and second positions where the supports are at approximately the same level and the second support is elevated relative to the first support, respectively. A first spring is supported by the first support and rotatably connected to the second support to bias the second support into the second position. A movable locking element biased by a second spring on the first support automatically blocks the second support in the second position. A locking element is movably supported by the first support and cooperates with a projection of the second support to lock the second support in the first position. A releasing element is movably supported by the first support and releases the locking element when actuated. A supporting member is located between the supports in the second position for transferring shock forces from the second support to the first support.
    • 颈部支架包括具有第一和第二位置的第一和第二支撑件,其中支撑件分别处于大致相同的水平面并且第二支撑件相对于第一支撑件升高。 第一弹簧由第一支撑件支撑并且可旋转地连接到第二支撑件,以将第二支撑件偏压到第二位置。 由第二弹簧偏置在第一支架上的可移动锁定元件在第二位置自动地阻挡第二支撑件。 锁定元件由第一支撑件可移动地支撑并与第二支撑件的突起配合,以将第二支撑件锁定在第一位置。 释放元件由第一支撑件可移动地支撑并且当致动时释放锁定元件。 支撑构件位于第二位置的支撑件之间,用于将冲击力从第二支撑件传递到第一支撑件。
    • 9. 发明授权
    • Cabriolet vehicle having a roof handhold arrangement
    • 敞篷车具有屋顶扶手装置
    • US6139086A
    • 2000-10-31
    • US263287
    • 1999-03-05
    • Gerd Fischer
    • Gerd Fischer
    • B60N3/02B60R13/01
    • B60N3/026
    • A vehicle having a roof handhold arrangement includes an openable and collapsible cabriolet roof with an elastically deformable handhold connected at each end to handhold attachment points on lateral structural members of a collapsible roof. The collapsible roof is collapsible at least between the handhold attachment points, reducing the distance between them, and the handhold is foldable into a roof fold extending transverse to the longitudinal direction of the vehicle and bulging toward the outside of the roof. Upon collapse of the cabriolet roof by the opposed motion of the handhold attachment points, the handhold is deformable from a service position into a storage position in a transverse fold region of the roof.
    • 具有屋顶手持装置的车辆包括可开启和折叠的敞篷车顶棚,其具有可弹性变形的手柄,每个端部连接到可收缩屋顶的侧向结构构件上的手持附接点。 可折叠屋顶至少在手持件附接点之间可折叠,减小了它们之间的距离,并且手柄可折叠成横向于车辆纵向方向延伸的屋顶折叠物并向屋顶外侧凸出。 通过手持件附接点的相对运动,敞篷车顶部被折叠时,把手可从服务位置变形到屋顶的横向折叠区域中的存放位置。