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1. 发明申请

US20150088156A1 SYSTEMS AND METHODS FOR TREATMENT OF DRY EYE 有权
公开(公告)号：US20150088156A1
公开(公告)日：2015-03-26
申请号：US14561107
申请日：2014-12-04
申请人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne MCCRAY , Brandon McNary FELKINS
发明人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne MCCRAY , Brandon McNary FELKINS
IPC分类号： A61N1/372 , A61N1/378 , A61N1/36 , A61N1/375
CPC分类号： A61N1/37205 , A61N1/36046 , A61N1/36057 , A61N1/3606 , A61N1/36142 , A61N1/37211 , A61N1/3756 , A61N1/3787
摘要： A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.

2. 发明申请

US20150335900A1 SYSTEMS AND METHODS FOR TREATMENT OF DRY EYE 审中-公开
标题翻译：用于治疗干眼症的系统和方法
公开(公告)号：US20150335900A1
公开(公告)日：2015-11-26
申请号：US14816846
申请日：2015-08-03
申请人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne MCCRAY , Brandon McNary FELKINS
发明人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne MCCRAY , Brandon McNary FELKINS
IPC分类号： A61N1/372
摘要： A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.
摘要翻译：刺激系统刺激患者的解剖目标以治疗干眼症。该系统可以包括控制器和微型激励器。控制器可以在微型激励器外部或内部实现。控制器和微型激励器的组件可以在单个单元中或在单独的设备中实现。当单独实现时，控制器和微型激励器可以无线地或经由有线连接进行通信。微型激励器可以从控制器信号产生脉冲，并通过一个或多个电极将信号施加到解剖靶。微型激励器可能没有任何智能或逻辑来塑造或修改信号。微型激励器可以是被配置为基于从控制器接收的信号产生脉冲的无源器件。微型激励器可以形成或修改信号。具有不同频率，幅度和周期特征的波形可以刺激患者中不同的解剖目标。

3. 发明申请

US20140055741A1 CONTACT LENS WITH A HYDROPHILIC LAYER 有权
标题翻译：接触透镜与水泥层
公开(公告)号：US20140055741A1
公开(公告)日：2014-02-27
申请号：US13975868
申请日：2013-08-26
申请人： Karen L. Havenstrite , Victor Wayne McCray , Brandon McNary Felkins , Douglas Michael Ackermann , Garrett Cale Smith , Paul A. Cook , Evan S. Luxon , Andrew A. McGibbon
发明人： Karen L. Havenstrite , Victor Wayne McCray , Brandon McNary Felkins , Douglas Michael Ackermann , Garrett Cale Smith , Paul A. Cook , Evan S. Luxon , Andrew A. McGibbon
IPC分类号： G02B1/04
CPC分类号： G02C7/049 , C08L5/08 , C08L71/00 , C08L2203/02 , C08L2205/025 , C09D105/08 , C09D171/00 , G02B1/043 , G02C2202/16 , C08L101/14
摘要： Embodiments of the technology relate to a contact lens having a core that is covalently coated by a hydrogel layer, and to methods of making such a lens. In one aspect, embodiments provide for a coated contact lens comprising a lens core comprising an outer surface; and a hydrogel layer covalently attached to at least a portion of the outer surface, the hydrogel layer adapted to contact an ophthalmic surface, wherein the hydrogel layer comprises a hydrophilic polymer population having a first PEG species and a second PEG species, the first PEG species being at least partially cross-linked to the second PEG species.
摘要翻译：该技术的实施方案涉及具有由水凝胶层共价涂覆的芯的隐形眼镜以及制造这种透镜的方法。在一个方面，实施例提供了一种涂覆的隐形眼镜，其包括包括外表面的透镜芯; 以及水凝胶层，其共价连接到所述外表面的至少一部分，所述水凝胶层适于接触眼表面，其中所述水凝胶层包含具有第一PEG种类和第二PEG物质的亲水聚合物群体，所述第一PEG种类至少部分地与第二PEG种类交联。

4. 发明申请

US20180154161A1 SYSTEMS AND METHODS FOR TREATMENT OF DRY EYE 审中-公开
公开(公告)号：US20180154161A1
公开(公告)日：2018-06-07
申请号：US15828950
申请日：2017-12-01
申请人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne McCRAY , Brandon McNary FELKINS
发明人： Douglas Michael ACKERMANN , Daniel PALANKER , James Donald LOUDIN , Garrett Cale SMITH , Victor Wayne McCRAY , Brandon McNary FELKINS
IPC分类号： A61N1/372 , A61N1/36 , A61N1/375 , A61N1/378
CPC分类号： A61N1/37205 , A61N1/36046 , A61N1/36057 , A61N1/3606 , A61N1/36142 , A61N1/37211 , A61N1/3756 , A61N1/3787
摘要： A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.

5. 发明授权

US08918181B2 Systems and methods for treatment of dry eye 有权
标题翻译：用于治疗干眼症的系统和方法
公开(公告)号：US08918181B2
公开(公告)日：2014-12-23
申请号：US13298042
申请日：2011-11-16
申请人： Douglas Michael Ackermann , Daniel Palanker , James Donald Loudin , Garrett Cale Smith , Victor Wayne McCray , Brandon McNary Felkins
发明人： Douglas Michael Ackermann , Daniel Palanker , James Donald Loudin , Garrett Cale Smith , Victor Wayne McCray , Brandon McNary Felkins
IPC分类号： A61N1/36 , A61N1/372 , A61N1/378 , A61N1/375
CPC分类号： A61N1/37205 , A61N1/36046 , A61N1/36057 , A61N1/3606 , A61N1/36142 , A61N1/37211 , A61N1/3756 , A61N1/3787
摘要： A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.
摘要翻译：刺激系统刺激患者的解剖目标以治疗干眼症。该系统可以包括控制器和微型激励器。控制器可以在微型激励器外部或内部实现。控制器和微型激励器的组件可以在单个单元中或在单独的设备中实现。当单独实现时，控制器和微型激励器可以无线地或经由有线连接进行通信。微型激励器可以从控制器信号产生脉冲，并通过一个或多个电极将信号施加到解剖靶。微型激励器可能没有任何智能或逻辑来塑造或修改信号。微型激励器可以是被配置为基于从控制器接收的信号产生脉冲的无源器件。微型激励器可以形成或修改信号。具有不同频率，幅度和周期特征的波形可以刺激患者中不同的解剖目标。

6. 发明申请

US20120130398A1 SYSTEMS AND METHODS FOR TREATMENT OF DRY EYE 有权
标题翻译：用于治疗干眼症的系统和方法
公开(公告)号：US20120130398A1
公开(公告)日：2012-05-24
申请号：US13298042
申请日：2011-11-16
申请人： Douglas Michael Ackermann , Daniel Palanker , James Donald Loudin , Garrett Cale Smith , Victor Wayne McCray , Brandon McNary Felkins
发明人： Douglas Michael Ackermann , Daniel Palanker , James Donald Loudin , Garrett Cale Smith , Victor Wayne McCray , Brandon McNary Felkins
IPC分类号： A61N1/36 , A61B19/00
CPC分类号： A61N1/37205 , A61N1/36046 , A61N1/36057 , A61N1/3606 , A61N1/36142 , A61N1/37211 , A61N1/3756 , A61N1/3787
摘要： A stimulation system stimulates anatomical targets in a patient for treatment of dry eye. The system may include a controller and a microstimulator. The controller may be implemented externally to or internally within the microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a controller signal and apply the signal via one or more electrodes to an anatomical target. The microstimulator may not have any intelligence or logic to shape or modify a signal. The microstimulator may be a passive device configured to generate a pulse based on a signal received from the controller. The microstimulator may shape or modify a signal. Waveforms having different frequency, amplitude and period characteristics may stimulate different anatomical targets in a patient.
摘要翻译：刺激系统刺激患者的解剖目标以治疗干眼症。该系统可以包括控制器和微型激励器。控制器可以在微型激励器外部或内部实现。控制器和微型激励器的组件可以在单个单元中或在单独的设备中实现。当单独实现时，控制器和微型激励器可以无线地或经由有线连接进行通信。微型激励器可以从控制器信号产生脉冲，并通过一个或多个电极将信号施加到解剖靶。微型激励器可能没有任何智能或逻辑来塑造或修改信号。微型激励器可以是被配置为基于从控制器接收的信号产生脉冲的无源器件。微型激励器可以形成或修改信号。具有不同频率，幅度和周期特征的波形可以刺激患者中不同的解剖目标。

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