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1. 发明授权

US08970579B2 Computer system and method for generating a 3D geometric model 有权
标题翻译：用于生成3D几何模型的计算机系统和方法
公开(公告)号：US08970579B2
公开(公告)日：2015-03-03
申请号：US12671014
申请日：2008-07-22
申请人： Pascal Muller , Gang Zeng , Luc Van Gool
发明人： Pascal Muller , Gang Zeng , Luc Van Gool
IPC分类号： G06T17/00 , G06K9/46 , G06T17/10
CPC分类号： G06F17/5004 , G06K9/4604 , G06T17/005 , G06T17/10
摘要： For generating a 3D geometric model (44) and/or a definition of the 3D geometric model from a single digital image of a building facade (4), a facade structure is detected from the digital image by dividing the facade (4) along horizontal lines into horizontal layers representative of floors (41), and by dividing the horizontal layers along vertical lines into tiles (42). The tiles (42) are further subdivided into a hierarchy of rectangular image regions (43). 3D architectural objects (45) corresponding to the image regions (43) are determined in an architectural element library. The 3D geometric model (44) or the definition of the 3D geometric model is generated based on the facade structure, the hierarchy and the 3D architectural objects (45). The library-based generation of the 3D geometric model makes it possible to enhance simple textured building models constructed from aerial images and/or ground-based photographs.
摘要翻译：为了从建筑立面（4）的单个数字图像生成3D几何模型（44）和/或3D几何模型的定义，通过将立面（4）沿水平方向分割，从数字图像检测立面结构将水平层划分成代表层（41）的水平层，并且通过沿着垂直线将水平层划分成瓦片（42）。瓦片（42）进一步细分为矩形图像区域（43）的层级。在建筑元素库中确定对应于图像区域（43）的3D建筑物体（45）。基于立面结构，层次结构和3D建筑对象（45）生成3D几何模型（44）或3D几何模型的定义。基于图书馆的3D几何模型可以增强由空中图像和/或地面照片构成的简单纹理建筑模型。

2. 发明授权

US08942815B2 Enhancing cochlear implants with hearing aid signal processing technologies 有权
标题翻译：用助听器信号处理技术增强人工耳蜗植入
公开(公告)号：US08942815B2
公开(公告)日：2015-01-27
申请号：US10805016
申请日：2004-03-19
申请人： King Chung , Fan-Gang Zeng
发明人： King Chung , Fan-Gang Zeng
IPC分类号： A61N1/00 , A61N1/36
CPC分类号： A61N1/36032 , A61N1/36036
摘要： A system and method that enhance the performance of cochlear implant signal processing in an amplification device. The system utilizes a signal input device that picks up the sounds from the environment or other hearing or audio devices and feeds the incoming signal into a front-end signal processor. The front-end processor pre-processes the signals and feeds them into a cochlear implant signal processor. The system may also insert a front-end processor into multiple signal processing stages of a cochlear implant signal processor with the front-end processor “sandwiched” between the multiple signal processing stages of the cochlear implant signal processors. The system may also insert a front-end processor into multiple signal processing stages of a cochlear implant signal processor with the front-end processor being either an integrated part of the cochlear implant signal processor or a functionally distinctive part for bilateral cochlear implants.
摘要翻译：一种增强放大装置中的人工耳蜗信号处理性能的系统和方法。该系统利用一个信号输入设备来拾取来自环境或其他听觉或音频设备的声音，并将输入信号馈送到前端信号处理器。前端处理器预处理信号并将其馈送到人工耳蜗信号处理器中。该系统还可以将前端处理器插入耳蜗植入信号处理器的多个信号处理阶段，其中前端处理器“夹在”人工耳蜗植入信号处理器的多个信号处理阶段之间。该系统还可以将前端处理器插入到耳蜗植入信号处理器的多个信号处理阶段中，其中前端处理器是耳蜗植入信号处理器的集成部分或用于双侧耳蜗植入物的功能特征部分。

3. 发明授权

US08754046B2 MHC class II restricted T cell epitopes from the cancer anitgen, NY ESO-1 有权
标题翻译： MHC II类限制性T细胞表位来自癌症anitgen，NY ESO-1
公开(公告)号：US08754046B2
公开(公告)日：2014-06-17
申请号：US12568134
申请日：2009-09-28
申请人： Rong-Fu Wang , Steven A. Rosenberg , Gang Zeng
发明人： Rong-Fu Wang , Steven A. Rosenberg , Gang Zeng
IPC分类号： A61P35/00
CPC分类号： A61K35/17 , A01K2217/05 , A61K38/00 , A61K38/08 , A61K39/00 , A61K45/06 , A61K48/00 , A61K2039/53 , C07K7/06 , C07K14/4748 , C07K16/30 , C07K2319/00 , C12N2799/021 , Y02A50/412
摘要： The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4+ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
摘要翻译：本发明公开了鉴定和分离衍生自癌症抗原NY ESO-1的新型MHC II类表位。来自NY-EsO-1的新型MHC II类表位以HLA II类限制性方式被识别，特别是HLA-DR或HLA-DP受限的CD4 + T淋巴细胞。该基因的产物是用于预防，治疗和诊断癌症患者的免疫治疗策略的有希望的候选者。

4. 发明授权

US08098859B2 Methods, devices and systems using signal processing algorithms to improve speech intelligibility and listening comfort 有权
标题翻译：使用信号处理算法的方法，设备和系统来提高语音清晰度和聆听舒适度
公开(公告)号：US08098859B2
公开(公告)日：2012-01-17
申请号：US11917320
申请日：2006-06-08
申请人： Fan-Gang Zeng , Sheng Liu
发明人： Fan-Gang Zeng , Sheng Liu
IPC分类号： H04R25/00 , A61N1/36 , A61F11/04
CPC分类号： H04R25/356 , H04R25/353 , H04R2225/43
摘要： Methods, devices and systems for improving hearing and for treating hearing disorders, such as auditory neuropathies. A hearing enhancement system of this invention generally comprises; an amplitude modulation processor, a frequency high-pass processor, a frequency upward-shifting processor and a formant upward-shifting processor.
摘要翻译：用于改善听力和治疗听觉障碍（如听觉神经病）的方法，装置和系统。本发明的听觉增强系统通常包括：振幅调制处理器，频率高通处理器，频率向上移位处理器和共振峰向上移位处理器。

5. 发明申请

US20100136527A1 Dominant B Cell Epitopes and Methods of Making and Using Thereof 有权
标题翻译：主导B细胞表位及其制备和使用方法
公开(公告)号：US20100136527A1
公开(公告)日：2010-06-03
申请号：US12182652
申请日：2008-07-30
申请人： Gang Zeng
发明人： Gang Zeng
IPC分类号： C12Q1/68 , C07K7/08 , C07K14/00 , C07K16/00 , G01N33/53 , C07K17/00
CPC分类号： G01N33/57484 , G01N33/574 , G01N33/6854 , G06F19/16
摘要： Disclosed are methods for obtaining at least one epitope suitable for detecting the presence of an antibody against a tumor associated antigen of a cancer in a sample. Kits, assays, and substrates employing the epitopes of the present invention are disclosed. Also disclosed are epitopes of NY-ESO-1 and XAGE-1b and methods of using thereof.
摘要翻译：公开了用于获得至少一种表位的方法，所述表位适合于检测针对样品中癌症相关抗原的抗体的抗体。公开了使用本发明的表位的试剂盒，测定法和底物。还公开了NY-ESO-1和XAGE-1b的表位及其使用方法。

6. 发明授权

US07444877B2 Optical waveguide vibration sensor for use in hearing aid 有权
标题翻译：用于助听器的光波导振动传感器
公开(公告)号：US07444877B2
公开(公告)日：2008-11-04
申请号：US10525279
申请日：2003-08-20
申请人： Guann-Pyng Li , Mark Bachman , Tao Xu , Fan-Gang Zeng , Patrick Coffey
发明人： Guann-Pyng Li , Mark Bachman , Tao Xu , Fan-Gang Zeng , Patrick Coffey
IPC分类号： G01D5/353 , H04R25/02 , G01D21/00
CPC分类号： H04R23/008 , G01H9/006 , H04R25/00 , Y10T29/49005 , Y10T29/49572
摘要： A directionally-sensitive device for detecting and processing vibration waves includes an array of polymeric optical waveguide resonators positioned between a light source, such as an LED array, and a light detector, such as a photodiode array. The resonators which are preferably oriented substantially perpendicularly with respect to incoming vibration waves, vibrate when a wave is detected, thus modulating light signals that are transmitted between the light source and the light detector. The light detector converts the modulated light into electrical signals which, in a preferred embodiment, are used to drive either the speaker of a hearing aid or the electrode array of a cochlear implant. The device is manufactured using a combination of traditional semiconductor processes and polymer microfabrication techniques.
摘要翻译：用于检测和处理振动波的定向敏感装置包括位于诸如LED阵列的光源和诸如光电二极管阵列的光检测器之间的聚合光波导谐振器的阵列。优选相对于输入的振动波基本上垂直地定向的谐振器在检测到波时振动，从而调制在光源和光检测器之间传输的光信号。光检测器将调制的光转换成电信号，其在优选实施例中用于驱动助听器的扬声器或耳蜗植入物的电极阵列。该器件采用传统半导体工艺和聚合物微细加工技术的结合制造。

7. 发明申请

US20050136402A1 Novel mhc class II restricted t cell epitopes from the cancer antigen, ny eso-1 有权
标题翻译：来自癌症抗原的新的mhc II类限制性t细胞表位，ny eso-1
公开(公告)号：US20050136402A1
公开(公告)日：2005-06-23
申请号：US10182506
申请日：2001-01-26
申请人： Rong-Fu Wang , Steven Rosenberg , Gang Zeng
发明人： Rong-Fu Wang , Steven Rosenberg , Gang Zeng
IPC分类号： C12N15/09 , A61K35/14 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/39 , A61K39/395 , A61K45/00 , A61K48/00 , A61P35/00 , C07K14/47 , C07K14/82 , C07K16/30 , C07K16/32 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12N7/00 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/91 , G01N33/574 , A61K38/17 , C07H21/04 , C07K14/74 , C12N15/86
CPC分类号： A61K35/17 , A01K2217/05 , A61K38/00 , A61K38/08 , A61K39/00 , A61K45/06 , A61K48/00 , A61K2039/53 , C07K7/06 , C07K14/4748 , C07K16/30 , C07K2319/00 , C12N2799/021 , Y02A50/412
摘要： The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4+ T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer.
摘要翻译：本发明公开了鉴定和分离衍生自癌症抗原NY ESO-1的新型MHC II类表位。来自NY-EsO-1的新型MHC II类表位以HLA II类限制性方式被识别，特别是HLA-DR或HLA-DP受限制的CD4 + T淋巴细胞。该基因的产物是用于预防，治疗和诊断癌症患者的免疫治疗策略的有希望的候选者。

8. 发明授权

US09173217B2 Base station calibration 有权
标题翻译：基站校准
公开(公告)号：US09173217B2
公开(公告)日：2015-10-27
申请号：US13701543
申请日：2010-06-03
申请人： Fan Teng , Chao Wei , Gang Zeng , Yufang Yin , Xuegang Huang
发明人： Fan Teng , Chao Wei , Gang Zeng , Yufang Yin , Xuegang Huang
IPC分类号： H04B1/04 , H04W72/04 , H01Q1/24 , H01Q3/26 , H03C1/62
CPC分类号： H04W72/0433 , H01Q1/246 , H01Q3/267 , H04B17/12 , H04B17/14 , H04B17/21
摘要： A method for calibrating a base station including a plurality of antennas is provided. First correction information is received from a system module, the correction information determined from first calibration of the base station Signals are received at a radio frequency module from at least one antenna of the base station Second correction information is determined on the basis of the received signals and the first correction information.
摘要翻译：提供了一种用于校准包括多个天线的基站的方法。从系统模块接收到第一校正信息，从基站的第一校准确定的校正信息从基站的至少一个天线在射频模块接收。基于接收信号确定第二校正信息和第一校正信息。

9. 发明授权

US08185383B2 Methods and apparatus for adapting speech coders to improve cochlear implant performance 有权
标题翻译：适应语音编码器以改善人工耳蜗植入性能的方法和装置
公开(公告)号：US08185383B2
公开(公告)日：2012-05-22
申请号：US11880240
申请日：2007-07-20
申请人： Fan-Gang Zeng , Hongbin Chen
发明人： Fan-Gang Zeng , Hongbin Chen
IPC分类号： G10L11/04
CPC分类号： G10L25/90 , A61N1/36036 , G10L19/125
摘要： Cochlear implant performance is improved by extracting pitch information and encoding such pitch information into the processor of a cochlear implant. One embodiment of the invention is to explicitly extract the pitch and deliver it to the cochlear implant by co-varying the stimulated site and rate. Another embodiment of the invention is to implicitly encode the pitch information via a code book that serves as the carrier of stimulation in the cochlear implant.
摘要翻译：通过提取音高信息并将这种音调信息编码到耳蜗植入物的处理器中来改善人工耳蜗植入性能。本发明的一个实施方案是明确地提取沥青并通过共同改变被刺激部位和速率将其递送到耳蜗植入物。本发明的另一实施例是通过用作耳蜗植入物中的刺激载体的码本来隐含地编码音调信息。

10. 发明申请

US20110311998A1 A+ Biomarker Assays 有权
标题翻译： A +生物标志物测定
公开(公告)号：US20110311998A1
公开(公告)日：2011-12-22
申请号：US13141525
申请日：2010-02-19
申请人： Gang Zeng
发明人： Gang Zeng
IPC分类号： G01N33/53
CPC分类号： G01N33/57434 , G01N33/536
摘要： Disclosed herein assay methods which comprise detecting the presence, absence or amount of at least one antibody which specifically binds a first biomarker or an epitope thereof and at least one second biomarker in a sample which comprises a single reaction step whereby both a first capture reagent for the antibody and a second capture reagent for the second biomarker are together contacted with the sample, and detecting the presence, absence or amount of the antibody, and detecting the presence, absence or amount of the second biomarker. Also disclosed are assay methods for prostate cancer.
摘要翻译：本文公开了测定方法，其包括检测特异性结合第一生物标志物或其表位的至少一种抗体的存在，不存在或量，以及样品中的至少一种第二生物标志物，其包含单个反应步骤，第二生物标志物的抗体和第二捕获试剂与样品一起接触，并检测抗体的存在，不存在或量，以及检测第二生物标志物的存在，不存在或量。还公开了前列腺癌的测定方法。

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