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    • 1. 发明授权
    • Device and process for nucleophilic fluorination
    • 用于亲核氟化的装置和方法
    • US07482498B2
    • 2009-01-27
    • US10840429
    • 2004-05-07
    • Peter MaedingFrank Fuechtner
    • Peter MaedingFrank Fuechtner
    • C07C17/00G10K11/00G01L25/00B01L3/00
    • C07B59/00A61K51/0459
    • The invention relates to a device and a process for nucleophilic fluorination of a substance, especially for synthesis of an 18F-labeled substance for examination using a positron emission tomograph. The device comprises an anion exchange device (102) for extraction of [18F]fluoride ions by means of adsorption from a target fluid, whereby the anion exchange device (102) can be charged via a supply device (101) with the target fluid; and a measurement device (104) with a measurement chamber (103) for measuring initial radioactivity of the [18F]fluoride ions, the anion exchange device (102) being arranged at least partially in the measurement chamber (103) of the measurement device (104).
    • 本发明涉及用于物质的亲核氟化的装置和方法,特别是用于合成用正电子发射断层扫描仪检查的18F标记物质。 该装置包括用于通过来自目标流体的吸附提取[18 F]氟化物离子的阴离子交换装置(102),由此阴离子交换装置(102)可以通过供应装置(101)与目标流体进行充电; 以及具有用于测量[18 F]氟离子的初始放射性的测量室(103)的测量装置(104),阴离子交换装置(102)至少部分地布置在测量装置的测量室(103)中 104)。
    • 2. 发明申请
    • DEVICE AND PROCESS FOR NUCLEOPHILIC FLUORINATION
    • 用于核燃料氟化的装置和方法
    • US20090005617A1
    • 2009-01-01
    • US10840429
    • 2004-05-07
    • Peter MaedingFrank Fuechtner
    • Peter MaedingFrank Fuechtner
    • C07C17/20C07C19/08G21C1/00
    • C07B59/00A61K51/0459
    • The invention relates to a device and a process for nucleophilic fluorination of a substance, especially for synthesis of an 18F-labeled substance for examination using a positron emission tomograph. The device comprises an anion exchange device (102) for extraction of [18F]fluoride ions by means of adsorption from a target fluid, whereby the anion exchange device (102) can be charged via a supply device (101) with the target fluid; and a measurement device (104) with a measurement chamber (103) for measuring initial radioactivity of the [18F]fluoride ions, the anion exchange device (102) being arranged at least partially in the measurement chamber (103) of the measurement device (104). (FIG. 1)
    • 本发明涉及用于物质的亲核氟化的装置和方法,特别是用于合成用正电子发射断层扫描仪检查的18F标记物质。 该装置包括用于通过来自目标流体的吸附提取[18 F]氟化物离子的阴离子交换装置(102),由此阴离子交换装置(102)可以通过供应装置(101)与目标流体进行充电; 以及具有用于测量[18 F]氟离子的初始放射性的测量室(103)的测量装置(104),阴离子交换装置(102)至少部分地布置在测量装置的测量室(103)中 104)。 (图。1)