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1. 发明授权

US07524883B2 Eponemycin and epoxomicin analogs and uses thereof 失效
标题翻译：环孢霉素和环氧素类似物及其用途
公开(公告)号：US07524883B2
公开(公告)日：2009-04-28
申请号：US10501120
申请日：2003-01-08
申请人： Sergei Agoulnik , Kozo Akasaka , Frank Fang , Jean-Christophe Harmange , Lynn Hawkins , Yimin Jiang , Charles Johannes , Xiang-Yi Li , Pamela McGuiness , Erin A. Murphy , Shawn Schiller , Mary Vermeulen , Jiayi Wu
发明人： Sergei Agoulnik , Kozo Akasaka , Frank Fang , Jean-Christophe Harmange , Lynn Hawkins , Yimin Jiang , Charles Johannes , Xiang-Yi Li , Pamela McGuiness , Erin A. Murphy , Shawn Schiller , Mary Vermeulen , Jiayi Wu
IPC分类号： C07D303/46 , A61K31/336
CPC分类号： C07D209/48 , A61K38/00 , C07D303/36 , C07D405/12 , C07D407/12 , C07F5/025 , C07F9/65502 , C07K5/06139
摘要： The present invention provides compounds having formula (1): wherein R1-R6, A, J, D, E, G, Q, w, x, y, and z are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of cancer and/or inflammatory disorders, and more generally as proteasome inhibitors.
摘要翻译：本发明提供了具有式（1）的化合物：其中R 1 -R 6，A，J，D，E，G，Q，w，x，y和z如本文中所述的类别和亚类所述，其药物组合物及其用于治疗癌症和/或炎症性疾病的方法，更一般地，作为蛋白酶体抑制剂。

2. 发明申请

US20120013102A1 Sliding Seat for Wheelchair Occupant to Enter and Exit Motor Vehicles 审中-公开
标题翻译：轮椅乘客滑行座椅进入和退出机动车辆
公开(公告)号：US20120013102A1
公开(公告)日：2012-01-19
申请号：US13184493
申请日：2011-07-16
申请人： Frank Fang Gao
发明人： Frank Fang Gao
IPC分类号： A61G5/10
CPC分类号： A61G5/10 , A61G3/02 , A61G3/0254 , A61G3/0281 , A61G3/063 , A61G5/1091 , A61G7/1025 , A61G2220/14
摘要： A sliding seat, being manufactured either together with a wheelchair as a component or separately as an accessory to a used wheelchair and aiming at helping a wheelchair occupant enter into or exit from a motor vehicle, comprises a supporting rack, a siding cushion, and an extender. The supporting rack has a top-board, a bottom frame, and a hoisting device in between. On the upward surface of the top-board, there are two crosswise sliding rulers. The sliding cushion has a soft cushion top and a solid baseboard which has two sliding sleeves on its downward surface to sheathe the sliding rulers of the top-board of the supporting rack. The extender also has two crosswise sliding rulers, which can connect with or disconnect from the sliding rulers of the top-board of the supporting rack. When being connected, the extender extends the two elongated sliding rulers into an open-door motor vehicle and lays them on the vehicle seat. Then, on the elongated sliding rulers, the sliding cushion and the wheelchair occupant on it can slide from the supporting rack into the vehicle and sit on the vehicle seat, or from the vehicle seat back onto the supporting rack.
摘要翻译：一个滑动座椅，作为一个组件或轮椅作为一个组件或分开地作为一个二手轮椅的附件制造，并且旨在帮助轮椅乘员进入或离开机动车辆，包括支撑架，侧板缓冲垫和延长剂支撑架有一个顶板，一个底架和一个提升装置。在顶板的向上表面上有两个横向滑动标尺。滑动缓冲垫具有柔软的衬垫顶部和实心的基板，其下表面上具有两个滑动套筒，以固定支撑架顶板的滑动标尺。扩展器还具有两个横向滑动尺，其可以与支撑架的顶板的滑动标尺连接或断开。当连接时，扩展器将两个细长的滑动标尺延伸到开门机动车辆中并将其放置在车辆座椅上。然后，在细长的滑动标尺上，滑动垫和轮椅乘员可以从支撑架滑入车辆中，坐在车辆座椅上，或者从车辆座椅靠背回到支撑架上。

3. 发明申请

US20140371285A1 THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE 审中-公开
标题翻译：治疗化合物及其相关使用方法
公开(公告)号：US20140371285A1
公开(公告)日：2014-12-18
申请号：US14370415
申请日：2013-01-07
申请人： Kevin Sprott , Michael Lewis , Hyeongwook Choi , Frank Fang , Mingde Shan , Tsvetelina I. Lazarova , Lin Li , M. Arshad Siddiqui , Robin Larouche-Gauthier , Alexandre Lemire
发明人： Kevin Sprott , Michael Lewis , Hyeongwook Choi , Frank Fang , Mingde Shan , Tsvetelina I. Lazarova , Lin Li , M. Arshad Siddiqui , Robin Larouche-Gauthier , Alexandre Lemire
IPC分类号： C07D493/20
CPC分类号： C07D493/20 , C07D519/00
摘要： Salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Dosage forms and kits comprising salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Methods of using salinomycin analogs, pharmaceutically acceptable compositions, dosage forms, and kits for the treatment of proliferative diseases, e.g., cancer, or microbial infections in a subject
摘要翻译：盐霉素类似物和含有盐霉素类似物的药学上可接受的组合物。包含盐霉素类似物和含有盐霉素类似物的药学上可接受的组合物的剂型和试剂盒。使用盐霉素类似物，药学上可接受的组合物，剂型和用于治疗受试者中增殖性疾病例如癌症或微生物感染的试剂盒的方法

4. 发明申请

US20120091955A1 Electric Vehicle Battery Recharge-Replacement System 审中-公开
标题翻译：电动汽车电池充电更换系统
公开(公告)号：US20120091955A1
公开(公告)日：2012-04-19
申请号：US13241179
申请日：2011-09-22
申请人： Frank Fang Gao
发明人： Frank Fang Gao
IPC分类号： H02J7/00
CPC分类号： H01M2/1083 , B60L50/66 , B60L53/305 , B60L53/80 , B60L58/21 , H01M2/1077 , Y02T10/7005 , Y02T10/7061 , Y02T10/7088 , Y02T90/124 , Y02T90/128 , Y02T90/14 , Y02T90/163
摘要： An electric vehicle battery recharge-replacement system has four major parts: (1) a rechargeable battery pack consisting of a number of separate sub-packs with an identical dimension and energy capacity, (2) a same number of battery sub-pack compartments on an electric vehicle, and all sub-pack compartments having an identical dimension, (3) a recharging array consisting of a number of individual recharging compartments stacking together, and each recharging compartment having a dimension same as the vehicle sub-pack compartment, and (4) some battery sub-pack holding cases, each of which having an identical dimension. With this system, battery pack replacement can be realized by replacing drained battery sub-packs in an electric vehicle's compartments with recharged battery sub-packs in a recharging array's compartments. In this system, each battery sup-pack can further consist of two to four identical sub-sub-packs, which are even lighter and easier to handle.
摘要翻译：电动车辆电池充电替换系统有四个主要部分：（1）可再充电电池组，由多个具有相同尺寸和能量容量的独立子组件组成，（2）相同数量的电池子组件隔间电动车辆和具有相同尺寸的所有子包厢隔间，（3）由堆叠在一起的多个单独充电室组成的再充电阵列，以及具有与车辆子舱室相同尺寸的每个充电舱，以及（ 4）一些电池子包装盒，每个具有相同的尺寸。利用该系统，可以通过在充电阵列的隔间中更换电动车辆隔室中的已充电电池子组件来更换排出的电池组件来实现电池组更换。在这个系统中，每个电池组件可以进一步包括两到四个相同的子子包，它们更轻，更易于处理。

5. 发明授权

US07642284B2 Luminacin analogs and uses thereof 失效
标题翻译：亮氨酸类似物及其用途
公开(公告)号：US07642284B2
公开(公告)日：2010-01-05
申请号：US12100194
申请日：2008-04-09
申请人： Frank Fang , Charles Johannes , Ye Yao , Xiaojie (Jeff) Zhu
发明人： Frank Fang , Charles Johannes , Ye Yao , Xiaojie (Jeff) Zhu
IPC分类号： A61K31/351 , C07D315/00
CPC分类号： C07D493/10 , C07D309/10
摘要： The present invention provides compounds having formula (I) (and pharmaceutically acceptable derivatives thereof): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1-R14 and n are as defined herein.
摘要翻译：本发明提供具有式（I）的化合物（及其药学上可接受的衍生物）：另外提供其合成方法及其用于治疗癌症的方法，其中R1-R14和n如本文所定义。

6. 发明申请

US20100026027A1 Vehicle Cargo Bed Extender-Tailgate Assembly 审中-公开
标题翻译：车载货物扩展器 - 尾门总成
公开(公告)号：US20100026027A1
公开(公告)日：2010-02-04
申请号：US12534107
申请日：2009-08-01
申请人： Frank Fang Gao
发明人： Frank Fang Gao
IPC分类号： B62D33/08
CPC分类号： B62D33/0273
摘要： A truck cargo bed extender-tailgate assembly has three extension boards that are hinged with the tailgate. When extra cargo volume is desired, the assembly is lowered to a horizontal position. The left and right extension sideboards fold up to upright positions and pinned respectively with the left sidewall and the right sidewall of the truck bed. The extension backboard folds up to an upright position and is pinned with the upright left extension sideboard and the upright right extension sideboard. With three extension boards at upright positions, the cargo bed is extended by an length equal to the height of the tailgate. The extension backboard can be lowered from its upright position backward to a horizontal position, further extending the cargo bed floor. When the extended cargo bed is no longer needed, three extension boards can be easily folded down to their stowed positions to resume the original vehicle length.
摘要翻译：一个卡车货床延长后挡板总成有三个与后挡板铰接的延伸板。当需要额外的货物体积时，组件被降低到水平位置。左右扩展侧板折叠到直立位置，分别与卡车车厢的左侧壁和右侧壁卡住。扩展背板折叠到直立位置，并与直立左侧延伸侧板和直立右侧延伸侧板固定。在三个延伸板处于直立位置时，货物床的延伸长度等于后挡板的高度。延伸背板可以从其直立位置向后降低到水平位置，进一步延伸货物底板。当不再需要扩展货舱时，可以将三个延伸板轻松折叠到收起位置，以恢复原车长度。

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