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1. 发明授权

US11278447B2 Portable thermal therapy and support apparatus for emergency medical treatment 有权
公开(公告)号：US11278447B2
公开(公告)日：2022-03-22
申请号：US16582723
申请日：2019-09-25
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A61F7/02 , A61F7/10 , A42B1/008 , A61F7/00
摘要： A thermal therapy headgear for a patient includes a plurality of thermal reaction compartments, a liquid chamber, a gas chamber, and a gas container. The thermal reaction compartments contain a first of at least two thermal reaction components, and the liquid chamber contains the second thermal reaction component. The gas container has therein a pressurized gas and a gas valve for selectively releasing the pressurized gas into the gas chamber. The gas in the gas chamber will apply pressure to the liquid chamber and force the second thermal reaction component through the valve and into the thermal reaction compartments to react and transfer heat with the patient, and the presence of the gas within the gas chamber will cushion the patient. A method for conducting hypothermic therapy is also disclosed.

2. 发明申请

US20080168847A1 Perifusion device 有权
标题翻译：灌注装置
公开(公告)号：US20080168847A1
公开(公告)日：2008-07-17
申请号：US11653193
申请日：2007-01-12
申请人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
发明人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
IPC分类号： G01N1/00
CPC分类号： C12M41/36 , C12M23/12 , C12M29/10 , C12M33/10 , C12M35/04 , C12M41/00 , C12M41/14 , C12M41/46
摘要： A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A receptacle housing has a plurality of receptacles for receiving fluid from the outlet of the sample container. A drive is connected to the receptacle housing for moving the receptacle housing such that liquid samples are collected sequentially from the outlet of the sample containers. A computer can be provided to control movement of the receptacle housing at predetermined times, and to record data identifying liquid samples in the receptacles. The test liquid includes at least one stimuli for the cells, which can be the presence, absence, or concentration of a compound in the liquid, or a physical property of the liquid such as temperature. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
摘要翻译：渗出装置包括用于细胞的至少一个样品容器，样品容器具有入口和出口。容器通过入口接收测试液体，并通过出口排出液体。插座壳体具有多个用于从样品容器的出口接收流体的容器。驱动器连接到插座壳体以移动插座壳体，使得液体样品从样品容器的出口依次收集。可以提供计算机以在预定时间控制插座壳体的运动，并且将识别液体样品的数据记录在容器中。测试液体包括细胞的至少一种刺激，其可以是液体中化合物的存在，不存在或浓度，或液体的物理性质如温度。分析收集在容器中的液体以确定细胞对刺激的反应。

3. 发明授权

US09615968B2 Portable rapid cooling, hypothermia inducing headgear apparatus for tissue preservation 有权
公开(公告)号：US09615968B2
公开(公告)日：2017-04-11
申请号：US14688694
申请日：2015-04-16
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A61F7/00 , A61F7/08 , A61F7/10 , A42B1/00 , A42B1/22 , A61F7/02
CPC分类号： A61F7/106 , A42B1/008 , A42B1/22 , A61F7/02 , A61F2007/0002 , A61F2007/0008 , A61F2007/0096 , A61F2007/0268 , A61F2007/0276
摘要： Hypothermic therapy headgear for patients includes a headpiece for engaging the head of the patient and a cooling member engaged to the headpiece for contacting at least one surface portion of the patient. The cooling member includes at least one cooling surface for contacting the surface portion of the patient, and at least two endothermic reaction components. The endothermic reaction components have an initial state where the endothermic reaction components are separated from contact with each other, and a treatment state in which the endothermic reaction components are placed into contact, wherein an endothermic reaction takes place and cools the cooling surface and the corresponding portion of the patient. An activation device selectively places the endothermic reaction components into the treatment state when a patient is in need of hypothermic therapy. A thermal therapy device and a method for administering thermal therapy are also disclosed.

4. 发明申请

US20150297397A1 PORTABLE RAPID COOLING, HYPOTHERMIA INDUCING HEADGEAR APPARATUS FOR TISSUE PRESERVATION 有权
标题翻译：便携式快速冷藏，用于组织保存的HYPOTHERMIA诱导头装置
公开(公告)号：US20150297397A1
公开(公告)日：2015-10-22
申请号：US14688694
申请日：2015-04-16
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A61F7/10 , A42B1/22 , A42B1/00
CPC分类号： A61F7/106 , A42B1/008 , A42B1/22 , A61F7/02 , A61F2007/0002 , A61F2007/0008 , A61F2007/0096 , A61F2007/0268 , A61F2007/0276
摘要： Hypothermic therapy headgear for patients includes a headpiece for engaging the head of the patient and a cooling member engaged to the headpiece for contacting at least one surface portion of the patient. The cooling member includes at least one cooling surface for contacting the surface portion of the patient, and at least two endothermic reaction components. The endothermic reaction components have an initial state where the endothermic reaction components are separated from contact with each other, and a treatment state in which the endothermic reaction components are placed into contact, wherein an endothermic reaction takes place and cools the cooling surface and the corresponding portion of the patient. An activation device selectively places the endothermic reaction components into the treatment state when a patient is in need of hypothermic therapy. A thermal therapy device and a method for administering thermal therapy are also disclosed.
摘要翻译：用于患者的低温治疗头带包括用于接合患者头部的头盔和与头部接合的冷却构件，用于接触患者的至少一个表面部分。冷却构件包括用于接触患者的表面部分的至少一个冷却表面和至少两个吸热反应组分。吸热反应组分具有吸热反应组分彼此分离的初始状态和吸热反应组分接触的处理状态，其中发生吸热反应并冷却冷却表面和相应的部分患者。当患者需要低温治疗时，激活装置选择性地将吸热反应组分置于治疗状态。还公开了热治疗装置和用于治疗热疗的方法。

5. 发明授权

US08785178B2 Perifusion device 有权
标题翻译：灌注装置
公开(公告)号：US08785178B2
公开(公告)日：2014-07-22
申请号：US11653193
申请日：2007-01-12
申请人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
发明人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
IPC分类号： C12M3/00 , C12M1/16 , C12M1/34 , C12M1/32 , C12M1/00 , C12M1/42 , C12M1/26
CPC分类号： C12M41/36 , C12M23/12 , C12M29/10 , C12M33/10 , C12M35/04 , C12M41/00 , C12M41/14 , C12M41/46
摘要： A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A receptacle housing has a plurality of receptacles for receiving fluid from the outlet of the sample container. A drive is connected to the receptacle housing for moving the receptacle housing such that liquid samples are collected sequentially from the outlet of the sample containers. A computer can be provided to control movement of the receptacle housing at predetermined times, and to record data identifying liquid samples in the receptacles. The test liquid includes at least one stimuli for the cells, which can be the presence, absence, or concentration of a compound in the liquid, or a physical property of the liquid such as temperature. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
摘要翻译：渗出装置包括用于细胞的至少一个样品容器，样品容器具有入口和出口。容器通过入口接收测试液体，并通过出口排出液体。插座壳体具有多个用于从样品容器的出口接收流体的容器。驱动器连接到插座壳体以移动插座壳体，使得液体样品从样品容器的出口依次收集。可以提供计算机以在预定时间控制插座壳体的运动，并且将识别液体样品的数据记录在容器中。测试液体包括细胞的至少一种刺激，其可以是液体中化合物的存在，不存在或浓度，或液体的物理性质如温度。分析收集在容器中的液体以确定细胞对刺激的反应。

6. 发明申请

US20210085519A1 PORTABLE THERMAL THERAPY AND SUPPORT APPARATUS FOR EMERGENCY MEDICAL TREATMENT 有权
公开(公告)号：US20210085519A1
公开(公告)日：2021-03-25
申请号：US16582723
申请日：2019-09-25
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A61F7/10 , A42B1/00
摘要： A thermal therapy headgear for a patient includes a plurality of thermal reaction compartments, a liquid chamber, a gas chamber, and a gas container. The thermal reaction compartments contain a first of at least two thermal reaction components, and the liquid chamber contains the second thermal reaction component. The gas container has therein a pressurized gas and a gas valve for selectively releasing the pressurized gas into the gas chamber. The gas in the gas chamber will apply pressure to the liquid chamber and force the second thermal reaction component through the valve and into the thermal reaction compartments to react and transfer heat with the patient, and the presence of the gas within the gas chamber will cushion the patient. A method for conducting hypothermic therapy is also disclosed.

7. 发明申请

US20130040324A1 PERIFUSION DEVICE 有权
标题翻译： PERIFUSION设备
公开(公告)号：US20130040324A1
公开(公告)日：2013-02-14
申请号：US13595697
申请日：2012-08-27
申请人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
发明人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
IPC分类号： C12M1/36 , C12Q1/54 , G01N33/566 , C12Q1/02
CPC分类号： C12M41/48 , B33Y80/00 , C12M23/12 , C12M23/40 , C12M23/42 , C12M41/00 , Y10T137/87249
摘要： A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A manifold having a plurality of liquid inlets, control valves, and liquid outlets can be provided. A receptacle housing has a plurality of receptacles. A drive is connected to the receptacle housing for moving the receptacle housing. A programmable controller can be provided to control movement of the receptacle housing. The test liquid includes at least one stimuli for the cells. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
摘要翻译：渗出装置包括用于细胞的至少一个样品容器，样品容器具有入口和出口。容器通过入口接收测试液体，并通过出口排出液体。可以提供具有多个液体入口，控制阀和液体出口的歧管。插座壳体具有多个插座。驱动器连接到插座壳体以移动插座壳体。可以提供可编程控制器来控制插座壳体的运动。测试液体包括用于细胞的至少一种刺激物。分析收集在容器中的液体以确定细胞对刺激的反应。

8. 发明授权

US10342696B2 Portable rapid cooling, hypothermia inducing headgear apparatus for tissue preservation 有权
公开(公告)号：US10342696B2
公开(公告)日：2019-07-09
申请号：US15480932
申请日：2017-04-06
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A42B1/00 , A42B1/22 , A61F7/00 , A61F7/02 , A61F7/10
摘要： Hypothermic therapy headgear for patients includes a headpiece for engaging the head of the patient and a cooling member engaged to the headpiece for contacting at least one surface portion of the patient. The cooling member includes at least one cooling surface for contacting the surface portion of the patient, and at least two endothermic reaction components. The endothermic reaction components have an initial state where the endothermic reaction components are separated from contact with each other, and a treatment state in which the endothermic reaction components are placed into contact, wherein an endothermic reaction takes place and cools the cooling surface and the corresponding portion of the patient. An activation device selectively places the endothermic reaction components into the treatment state when a patient is in need of hypothermic therapy. A thermal therapy device and a method for administering thermal therapy are also disclosed.

9. 发明申请

US20170209306A1 PORTABLE RAPID COOLING, HYPOTHERMIA INDUCING HEADGEAR APPARATUS FOR TISSUE PRESERVATION 审中-公开
公开(公告)号：US20170209306A1
公开(公告)日：2017-07-27
申请号：US15480932
申请日：2017-04-06
申请人： David Rand , William Rand , Felipe Echeverri
发明人： David Rand , William Rand , Felipe Echeverri
IPC分类号： A61F7/10 , A42B1/00 , A42B1/22 , A61F7/02
CPC分类号： A61F7/106 , A42B1/008 , A42B1/22 , A61F7/02 , A61F2007/0002 , A61F2007/0008 , A61F2007/0096 , A61F2007/0268 , A61F2007/0276
摘要： Hypothermic therapy headgear for patients includes a headpiece for engaging the head of the patient and a cooling member engaged to the headpiece for contacting at least one surface portion of the patient. The cooling member includes at least one cooling surface for contacting the surface portion of the patient, and at least two endothermic reaction components. The endothermic reaction components have an initial state where the endothermic reaction components are separated from contact with each other, and a treatment state in which the endothermic reaction components are placed into contact, wherein an endothermic reaction takes place and cools the cooling surface and the corresponding portion of the patient. An activation device selectively places the endothermic reaction components into the treatment state when a patient is in need of hypothermic therapy. A thermal therapy device and a method for administering thermal therapy are also disclosed.

10. 发明授权

US08865427B2 Perifusion device 有权
标题翻译：灌注装置
公开(公告)号：US08865427B2
公开(公告)日：2014-10-21
申请号：US13595697
申请日：2012-08-27
申请人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
发明人： Ramon E. Poo , Camillo Ricordi , Felipe Echeverri , Over Cabrera , Per-Olof Berggren
IPC分类号： C12Q1/18 , C12M3/00 , C12M1/34 , C12M1/00 , C12M1/32
CPC分类号： C12M41/48 , B33Y80/00 , C12M23/12 , C12M23/40 , C12M23/42 , C12M41/00 , Y10T137/87249
摘要： A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A manifold having a plurality of liquid inlets, control valves, and liquid outlets can be provided. A receptacle housing has a plurality of receptacles. A drive is connected to the receptacle housing for moving the receptacle housing. A programmable controller can be provided to control movement of the receptacle housing. The test liquid includes at least one stimuli for the cells. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
摘要翻译：渗出装置包括用于细胞的至少一个样品容器，样品容器具有入口和出口。容器通过入口接收测试液体，并通过出口排出液体。可以提供具有多个液体入口，控制阀和液体出口的歧管。插座壳体具有多个插座。驱动器连接到插座壳体以移动插座壳体。可以提供可编程控制器来控制插座壳体的运动。测试液体包括用于细胞的至少一种刺激物。分析收集在容器中的液体以确定细胞对刺激的反应。

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