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    • 1. 发明申请
    • COMPOSITIONS AND METHODS FOR RELIEF FROM COLD SORES
    • 用于缓解冷冻的组合物和方法
    • US20160058818A1
    • 2016-03-03
    • US14838354
    • 2015-08-27
    • Boris GorinshteynF. Russell Denton
    • Boris GorinshteynF. Russell Denton
    • A61K36/752A61K31/4166A61K36/71A61K36/534A61K9/00A61K36/28
    • A61K36/752A61K9/0014A61K9/06A61K31/4166A61K36/28A61K36/29A61K36/534A61K36/71A61K36/718A61K47/44A61K2300/00
    • The invention provides compositions and methods that relieve pain and reduce the duration of cold sore episodes to a period of at most 3 to 5 days. Specifically, the invention provides a combination of extracts of bitter orange (Citrus x aurantium), yarrow (Achillea millefolium) and at least one of goldenseal (Hydrastis canadensis)), barberry (Berberis vulgaris) and Chinese goldthread (Coptis chinensis); the invention may be used in the form of a cream, lipstick or other topical composition dosing format to treat and prevent cold sore episodes. In certain embodiments the compositions include further ingredients such as an analgesic natural composition from the mint genus (Mentha), a protective coat-forming substance, a substance for promoting general health of skin, a substance to modify the color of the product a substance to modify the flavor of the product, a preservative, and/or a substance to modify the texture, viscosity or mechanical strength of the composition.
    • 本发明提供减轻疼痛并将冷疮发作的持续时间减少至多3至5天的组合物和方法。 具体地说,本发明提供了苦橙(Citrus x aurantium),蓍草(Achillea millefolium)和金缕梅(Hydrastis canadensis)中的至少一种,小檗(Berberis vulgaris)和中国黄连(黄连)的至少一种提取物的组合。 本发明可以以霜剂,口红或其它局部组合物给药方式的形式使用,以治疗和预防冷疮发作。 在某些实施方案中,组合物包括另外的成分,例如薄荷属(Mentha)的止痛天然组合物,保护性涂层形成物质,促进皮肤一般健康的物质,将物质的颜色改变为 改变产品的风味,防腐剂和/或物质以改变组合物的质地,粘度或机械强度。