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    • 5. 发明授权
    • Method for screening antioxidant using mutant bacteria and chlorophyllide, and antioxidant screened by the method
    • 使用突变型细菌和叶绿素来筛选抗氧化剂的方法,以及通过该方法筛选的抗氧化剂
    • US07892780B2
    • 2011-02-22
    • US12011275
    • 2008-01-24
    • Jeong-Kug LeeHae-Jin RheeEui-Jin KimMoon-Hee Sung
    • Jeong-Kug LeeHae-Jin RheeEui-Jin KimMoon-Hee Sung
    • C12Q1/26
    • C12Q1/025G01N2333/90283
    • Disclosed is a method for screening an antioxidant using mutant bacteria and chlorophyllide, and an antioxidant screened by the same method. The method provides for screening of an antioxidant by monitoring growth profiles of specific mutant bacteria in filter discs or medium blocks containing chlorophyllide added thereto, and an antioxidant screened by the same method. By monitoring growth profiles of mutant bacteria using mutant bacteria and chlorophyllide, screening of an antioxidant is possible on an industrial scale. In particular, the antioxidant screening method is useful for selective screening of an amphiphilic antioxidant. Therefore, it is possible to screen and commercialize low-toxic and effective antioxidants used in various food and cosmetic additives, as well as therapeutic medicines.
    • 公开了使用突变细菌和叶绿素来筛选抗氧化剂的方法,以及通过相同方法筛选的抗氧化剂。 该方法通过监测加入其中的含有叶绿素的滤膜或培养基中的特异性突变细菌的生长曲线和通过相同方法筛选的抗氧化剂来筛选抗氧化剂。 通过使用突变细菌和叶绿素来监测突变细菌的生长情况,可以在工业规模上筛选抗氧化剂。 特别地,抗氧化剂筛选方法可用于选择性筛选两亲性抗氧化剂。 因此,可以筛选和商业化各种食品和化妆品添加剂中使用的低毒和有效的抗氧化剂以及治疗药物。
    • 9. 发明申请
    • Method for screening antioxidant using mutant bacteria and chlorophyllide, and antioxidant screened by the method
    • 使用突变型细菌和叶绿素来筛选抗氧化剂的方法,以及通过该方法筛选的抗氧化剂
    • US20080305511A1
    • 2008-12-11
    • US12011275
    • 2008-01-24
    • Jeong-Kug LeeHae-Jin RheeEui-Jin KimMoon-Hee Sung
    • Jeong-Kug LeeHae-Jin RheeEui-Jin KimMoon-Hee Sung
    • C12Q1/26
    • C12Q1/025G01N2333/90283
    • Disclosed is a method for screening an antioxidant using mutant bacteria and chlorophyllide, and an antioxidant screened by the same method. More specifically, provided is a method for easy screening of an antioxidant by monitoring growth profiles of specific mutant bacteria in filter discs or medium blocks containing chlorophyllide added thereto, and an antioxidant screened by the same method.The present invention enables easy screening of an antioxidant on an industrial scale, by monitoring growth profiles of mutant bacteria via the use of mutant bacteria and chlorophyllide. In particular, the antioxidant screening method in accordance with the present invention is very useful for selective screening of an amphiphilic antioxidant. Therefore, the present invention is applicable to screen and commercialize low-toxic and effective antioxidants which will be used in various food and cosmetic additives as well as therapeutic medicines.
    • 公开了使用突变细菌和叶绿素来筛选抗氧化剂的方法,以及通过相同方法筛选的抗氧化剂。 更具体地,提供了通过监测添加有叶绿素的过滤盘或介质块中的特定突变体细菌的生长曲线以及通过相同方法筛选的抗氧化剂来容易地筛选抗氧化剂的方法。 通过使用突变细菌和叶绿素来监测突变细菌的生长情况,本发明能够在工业规模上容易地筛选抗氧化剂。 特别地,根据本发明的抗氧化剂筛选方法对于选择性筛选两亲抗氧化剂是非常有用的。 因此,本发明适用于将用于各种食品和化妆品添加剂以及治疗药物的低毒和有效的抗氧化剂的筛选和商业化。