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1. 发明授权

US06616594B2 Cartridge-moveable shield 失效
公开(公告)号：US06616594B2
公开(公告)日：2003-09-09
申请号：US09858653
申请日：2001-05-17
申请人： Diego Y. Fontayne , Daniel E. Ueda , Edward J. Kaplan , Steven S. Ravins , Ernest A. Elgin, III
发明人： Diego Y. Fontayne , Daniel E. Ueda , Edward J. Kaplan , Steven S. Ravins , Ernest A. Elgin, III
IPC分类号： A61M3700
CPC分类号： A61N5/1027 , A61M37/0069 , A61N2005/101
摘要： A cartridge is configured to be inserted into a medical instrument for treating patients with radioactive seeds. The cartridge includes a rotating internal barrel that is loaded with a plurality of seeds, where the internal barrel has a plurality of conduits for accepting the seeds. As the internal barrel rotates, a seed from one of the conduits is deposited into a shuttle, and then the shuttle is fully extended so as to provide the seed to the medical instrument. The shuttle is then retracted, and the barrel is rotated to the next conduit, so as to receive a seed from that next conduit. The cartridge includes a first shield and a second shield, each having slots where the slots of the first and second shields are aligned in a first verification or calibration mode, and where the slots are not aligned in a normal, seed depositing mode. The second shield also includes a plurality of numeric indicators that indicate a current number of seeds remaining in the cartridge.

2. 发明授权

US06428463B1 Fiberoptic-guided interstitial seed manual applicator and seed cartridge 失效
标题翻译：光纤导向间质种子手动施放器和种子筒
公开(公告)号：US06428463B1
公开(公告)日：2002-08-06
申请号：US09512451
申请日：2000-02-24
申请人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
发明人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
IPC分类号： A61N500
CPC分类号： A61M37/0069 , A61B90/36 , A61B2090/306 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1011
摘要： A method for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.
摘要翻译：将种子植入患者体内的目标区域（例如肿瘤）周围的方法。植入装置包括具有从针的近端到远端纵向穿过的孔的注射针，所述针孔适于允许至少一个种子通过。细长柱塞沿对准的针孔延伸穿过植入装置。光学装置被携带并且可操作地连接到柱塞，以向植入装置的操作者提供视觉辅助以引导和验证将喷射的种子植入到目标区域中。

3. 发明授权

US6102844A Fiberoptic-guided interstitial seed manual applicator and seed cartridge 失效
标题翻译：光纤导向间质种子手动施放器和种子筒
公开(公告)号：US6102844A
公开(公告)日：2000-08-15
申请号：US763759
申请日：1996-12-11
申请人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
发明人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
IPC分类号： A61B17/00 , A61B17/064 , A61B17/068 , A61B19/00 , A61M36/04 , A61M36/12 , A61N5/00 , A61N5/10 , A61M36/00
CPC分类号： A61M37/0069 , A61N5/1007 , A61B2090/306 , A61B90/36 , A61N2005/101 , A61N2005/1011 , A61N5/1027
摘要： A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore to eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area. A seed cartridge is releasably connected to the implantation device to store unused seeds and to load the seeds into the implantation device.
摘要翻译：用于在患者体内或周围的靶区域（例如肿瘤）内植入种子的方法和装置。植入装置包括具有从针的近端到远端纵向穿过的孔的注射针，所述针孔适于允许至少一个种子通过。细长的柱塞沿对准的针孔延伸穿过注入装置，并且可以相对于针从相对于针间隔开的缩回位置的纵向方向可移动到延伸位置，其中柱塞前进穿过针孔，通过孔将至少一个种子排出针的远端并进入目标区域。光学装置被携带并且可操作地连接到柱塞，以向植入装置的操作者提供视觉辅助以引导和验证将喷射的种子植入到目标区域中。种子筒可释放地连接到植入装置以存储未使用的种子并将种子加载到植入装置中。

4. 发明授权

US06508755B1 Fiberoptic-guided interstitial seed manual applicator and seed cartridge 失效
标题翻译：光纤导向间质种子手动施放器和种子筒
公开(公告)号：US06508755B1
公开(公告)日：2003-01-21
申请号：US09512450
申请日：2000-02-24
申请人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
发明人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
IPC分类号： A61N500
CPC分类号： A61M37/0069 , A61B90/36 , A61B2090/306 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1011
摘要： A method and apparatus for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal and to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore and is selectively movable in the longitudinal direction relative the needle from a retracted position spaced apart from the needle to an extended position wherein the plunger is advanced through the needle bore to eject at least one of the seeds through the bore, out of the distal end of needle and into the target area. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area. A seed cartridge is releasably connected to the implantation device to store unused seeds and to load the seeds into the implantation device.
摘要翻译：用于在患者体内或周围的靶区域（例如肿瘤）内植入种子的方法和装置。植入装置包括具有从针的近端和远端纵向穿过的孔的注射针，所述针孔适于允许至少一个种子通过。细长的柱塞沿对准的针孔延伸穿过注入装置，并且可以相对于针从相对于针间隔开的缩回位置的长度方向可移动到延伸位置，其中柱塞前进穿过针孔，通过孔将至少一个种子排出针的远端并进入目标区域。光学装置被携带并且可操作地连接到柱塞，以向植入装置的操作者提供视觉辅助以引导和验证将喷射的种子植入到目标区域中。种子筒可释放地连接到植入装置以存储未使用的种子并将种子加载到植入装置中。

5. 发明授权

US06432035B1 Fiberoptic-guided interstitial seed manual applicator and cartridge 失效
标题翻译：光纤引导的间质种子手动施放器和药筒
公开(公告)号：US06432035B1
公开(公告)日：2002-08-13
申请号：US09512452
申请日：2000-02-24
申请人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
发明人： Steven S. Ravins , Edward Kaplan , Ernest A. Elgin, III
IPC分类号： A61N500
CPC分类号： A61M37/0069 , A61B90/36 , A61B2090/306 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1011
摘要： A method for implanting seeds in or about a target area, such as a tumor, within a patient. The implantation device includes an implantation needle having a bore extending longitudinally therethrough from a proximal end to a distal end of the needle, the needle bore being adapted to permit at least one seed to pass therethrough. An elongated plunger extends longitudinally through the implantation device in aligned relation to the needle bore. An optical device is carried by and operatively connected to the plunger to provide visual assistance to an operator of the implantation device to guide and verify implantation of the ejected seed into the target area.
摘要翻译：将种子植入患者体内的目标区域（例如肿瘤）周围的方法。植入装置包括具有从针的近端到远端纵向延伸的孔的注射针，所述针孔适于允许至少一个种子通过。细长柱塞沿对准的针孔延伸穿过植入装置。光学装置被携带并且可操作地连接到柱塞，以向植入装置的操作者提供视觉辅助以引导和验证将喷射的种子植入到目标区域中。

6. 发明授权

US06575890B2 Medical instrument 失效
公开(公告)号：US06575890B2
公开(公告)日：2003-06-10
申请号：US09858658
申请日：2001-05-17
申请人： Edward J. Kaplan , Diego Y. Fontayne , Robert A. Joachim , Steven Bellofatto , Troy H. Phipps , Ernest A. Elgin, III
发明人： Edward J. Kaplan , Diego Y. Fontayne , Robert A. Joachim , Steven Bellofatto , Troy H. Phipps , Ernest A. Elgin, III
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61M2005/3289 , A61N5/1007 , A61N5/1027 , A61N2005/1011 , A61N2005/1012
摘要： A medical instrument provides for precise indexing in order to implant seeds into seed implant locations within a patient. The medical instrument is affixed to a targeting fixture, and upon operator actuation of a trigger, is automatically indexed from one seed implant location to a next seed implant location.

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