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1. 发明授权

US08187685B2 Window envelopes with scratch resistant window film patches 失效
标题翻译：窗口信封带有抗刮擦的窗膜贴片
公开(公告)号：US08187685B2
公开(公告)日：2012-05-29
申请号：US12376520
申请日：2007-07-23
申请人： Nichole E. Nickel , Eric K. Lee , Stephen J. Skapik, III , Donald J. Gromacki , Robert A. Gunther , James P. Maher
发明人： Nichole E. Nickel , Eric K. Lee , Stephen J. Skapik, III , Donald J. Gromacki , Robert A. Gunther , James P. Maher
IPC分类号： B32B1/08 , B32B27/10 , B32B27/32 , C08L51/04 , C08L53/02 , B65D27/04
CPC分类号： B65D27/04 , C08J5/18 , C08J2325/04 , Y10T428/13 , Y10T428/1303 , Y10T428/1352 , Y10T428/1397 , Y10T428/31855 , Y10T428/31938
摘要： The invention includes a composition comprising from 40 to 98 weight percent of at least one GPPS, from 0 to 98 weight percent of at least one HIPS, from 0.5 to 10 weight percent at least one styrene block copolymer, from 0.5 to 10 weight percent of at least one polypropylene wherein the combination of GPPS, HIPS, polypropylene and styrene block copolymer make up at least about 90 percent of the composition as well as a film made of the composition, an envelope window patch comprising the film, an envelope comprising the window patch, and a process for making the film.
摘要翻译：本发明包括组合物，其包含40至98重量％的至少一个GPPS，0至98重量％的至少一种HIPS，0.5至10重量％的至少一种苯乙烯嵌段共聚物，0.5至10重量％至少一种聚丙烯，其中GPPS，HIPS，聚丙烯和苯乙烯嵌段共聚物的组合构成组合物的至少约90％，以及由该组合物制成的膜，包括该膜的包膜窗贴片，包括该窗口的信封补丁，以及制作电影的过程。

2. 发明申请

US20090158755A1 SYSTEMS AND METHODS FOR FREEZING, STORING AND THAWING BIOPHARMACEUTICAL MATERIALS 有权
标题翻译：冷冻，储存和治疗生物材料的系统和方法
公开(公告)号：US20090158755A1
公开(公告)日：2009-06-25
申请号：US11963106
申请日：2007-12-21
申请人： Jonathan Cutting , Isabelle Gay , Eric K. Lee , Nicolas Voute
发明人： Jonathan Cutting , Isabelle Gay , Eric K. Lee , Nicolas Voute
IPC分类号： F25D3/00 , F25C1/00
CPC分类号： F17C3/085 , A01N1/02 , A01N1/0263 , B01L7/00 , F25C1/22 , Y10T29/53443
摘要： A system for using freezing, storing and thawing biopharmaceutical materials which includes a holder and a container for holding biopharmaceutical materials therein. The holder has a cavity and the container is received in the cavity. The holder includes a first portion and second portion. The container is received between the first portion and the second portion to connect the container to the holder. The holder includes an interior cradle having a bottom and edges extending from the bottom. The cradle bounds the cavity. An outer rim is connected to the cradle and separated from the cavity. The bottom includes an inner surface facing the cavity receiving the container and an outer surface. The outer surface of the bottom is recessed relative to an outer surface of the outer rim.
摘要翻译：一种用于使用冷冻，储存和解冻生物药物材料的系统，其包括用于在其中保持生物药物材料的保持器和容器。保持器具有空腔并且容器容纳在空腔中。保持器包括第一部分和第二部分。容器容纳在第一部分和第二部分之间，以将容器连接到保持器。保持器包括具有从底部延伸的底部和边缘的内部支架。摇篮限定了空腔。外缘连接到支架并与空腔分离。底部包括面向容纳容器的空腔的内表面和外表面。底部的外表面相对于外缘的外表面凹陷。

3. 发明授权

US06369394B1 Method and apparatus for irradiating a biological fluid 失效
标题翻译：用于照射生物流体的方法和装置
公开(公告)号：US06369394B1
公开(公告)日：2002-04-09
申请号：US09261602
申请日：1999-02-26
申请人： Eric K. Lee
发明人： Eric K. Lee
IPC分类号： G01N2100
CPC分类号： A61L2/0011 , A61L2/08 , B01F11/0065 , B01F13/0001 , B01F13/001 , C12N7/04
摘要： An apparatus and method for illuminating a fluid having photosensitive material therein comprising a surface and a roller separated from the surface by a space. The space is adapted to receive a flexible container therein. The flexible container on the surface contacts the roller and the surface for translation through the space. A light source is adapted to transmit light to the space to illuminate the fluid and react with the photosensitive material as the flexible container translates through the space.
摘要翻译：一种用于照亮其中具有感光材料的流体的装置和方法，其中包括一个表面和一个通过一个空间从该表面分离的辊。该空间适于在其中容纳柔性容器。表面上的柔性容器接触辊子和表面，以便通过该空间进行平移。光源适于将光传输到空间以照亮流体，并且随着柔性容器翻转通过空间而与感光材料反应。

4. 发明授权

US5143526A Process of treating alcoholic beverages by vapor-arbitrated pervaporation 失效
标题翻译：通过蒸汽仲裁渗透蒸发处理酒精饮料的过程
公开(公告)号：US5143526A
公开(公告)日：1992-09-01
申请号：US695040
申请日：1991-05-02
申请人： Eric K. Lee , Vinay J. Kalyani , Stephen L. Matson
发明人： Eric K. Lee , Vinay J. Kalyani , Stephen L. Matson
IPC分类号： B01D3/32 , B01D11/04 , B01D61/36 , B01D61/38 , C12G3/08 , C12H3/04
CPC分类号： C12G3/085 , B01D11/0415 , B01D3/322 , B01D61/362
摘要： The method and apparatus of the present invention has general applicability to the manipulation of the concentration, by partial depletion or enrichment, of one or more volatile components in a given liquid while leaving the other volatile components in the liquid in a substantially undisturbed or unadulterated state.
摘要翻译：本发明的方法和装置通常适用于通过部分耗尽或浓缩处理给定液体中一种或多种挥发性组分的浓度，同时将基本上未受干扰或未掺杂的状态的液体中的其它挥发性组分留下。

5. 发明授权

US08298638B2 Bubble stability 有权
标题翻译：气泡稳定
公开(公告)号：US08298638B2
公开(公告)日：2012-10-30
申请号：US12444789
申请日：2007-10-17
申请人： Douglas E. Beyer , Hyun K. Jeon , Eric K. Lee
发明人： Douglas E. Beyer , Hyun K. Jeon , Eric K. Lee
IPC分类号： B29D22/00 , B29D23/00 , B32B1/08
CPC分类号： C08F214/08 , Y10T428/1352 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383 , Y10T428/139 , Y10T428/1393 , Y10T428/1397 , C08F2/18
摘要： The invention includes a copolymer of vinylidene chloride with at least one monounsaturated comonomer and at least one branching monomer in an amount sufficient to increase molecular weight over that of a polymer prepared using the same process and same monomers in the same relative amounts except without the branching monomer, but preferably the branching monomer is present in a quantity not sufficient to result in measurable crosslinking as determined by solubility in tetrahydrofuran at up to 83° C. The invention includes a process for making the polymer and processes for forming the copolymer or compositions thereof as well as articles comprising the copolymer and compositions thereof. The copolymer exhibits improved bubble stability and is particularly useful for processes in which the copolymer is at least partially oriented in formation such as blow molding, formation of monofilament fiber and film blowing.
摘要翻译：本发明包括偏二氯乙烯与至少一种单不饱和共聚单体和至少一种支化单体的共聚物，其量足以增加分子量超过使用相同方法制备的聚合物的分子量和相同相同量的相同单体，除了不含支链单体，但优选支化单体的存在量不足以导致可测量的交联，如通过在高达83℃下在四氢呋喃中的溶解度测定。本发明包括制备聚合物的方法和形成共聚物或其组合物的方法以及包含共聚物及其组合物的制品。共聚物表现出改善的气泡稳定性，并且特别适用于其中共聚物在形成中至少部分取向的方法，例如吹塑，单丝纤维的形成和吹膜。

6. 发明申请

US20120017609A1 SYSTEMS AND METHODS FOR FREEZING, STORING AND THAWING BIOPHARMACEUTICAL MATERIALS 有权
标题翻译：用于冷冻，储存和治疗生物材料的系统和方法
公开(公告)号：US20120017609A1
公开(公告)日：2012-01-26
申请号：US13213638
申请日：2011-08-19
申请人： Nicolas VOUTE , Eric K. LEE , Dimitry YAKOUSHKIN
发明人： Nicolas VOUTE , Eric K. LEE , Dimitry YAKOUSHKIN
IPC分类号： F25D25/00 , F25D23/00
CPC分类号： F25D25/005 , A61J1/165 , F25D2331/809
摘要： A system for use in freezing, storing and thawing biopharmaceutical materials includes a flexible sterile container means for holding biopharmaceutical material therein and a holder more rigid than said container means. The container means is received in a cavity of the holder and the holder extends along a perimeter of the container means. The holder is fixedly connected to the container means. The holder includes opposing sides defining an opening and the container means extends between the opposing sides of the holder defining the opening. The container means includes a substantially smooth exterior surface extending between the opposing sides.
摘要翻译：用于冷冻，储存和解冻生物药物材料的系统包括用于在其中保持生物药物材料的柔性无菌容器装置和比所述容器装置更刚性的保持器。容器装置被容纳在保持器的空腔中，并且保持器沿着容器装置的周边延伸。保持器固定地连接到容器装置。保持器包括限定开口的相对侧，并且容器装置在限定开口的保持器的相对侧之间延伸。容器装置包括在相对的侧面之间延伸的基本光滑的外表面。

7. 发明授权

US07353658B2 Systems and methods for freezing, storing, transporting, and thawing biopharmacuetical material 失效
标题翻译：冷冻，储存，运输和解冻生物药物学材料的系统和方法
公开(公告)号：US07353658B2
公开(公告)日：2008-04-08
申请号：US11501329
申请日：2006-08-09
申请人： Nicolas Voute , Eric K. Lee , James Edward DeBeers , Brian J. Woodard , Ngee Jenn Lee
发明人： Nicolas Voute , Eric K. Lee , James Edward DeBeers , Brian J. Woodard , Ngee Jenn Lee
IPC分类号： F25D15/00
CPC分类号： F25D25/005 , A01N1/00 , A01N1/02 , A01N1/0257 , A01N1/0263 , A01N31/02 , A23L3/364 , A23L3/365 , A61G12/001 , A61J1/165 , A61M1/0272 , A61M1/0277 , A61M1/0281 , A61M2209/084 , F25B2600/07 , F25D25/00 , F25D31/001 , F25D2331/801 , F25D2331/8014 , F25D2400/20 , F25D2400/30 , F25D2500/02 , Y10S165/919 , A01N2300/00
摘要： A system for freezing, thawing, transporting, and storing a biopharmaceutical material, which includes a container, a supporting structure, a temperature control unit, and a transportation cart. The container is adapted to receive the biopharmaceutical material therein for freezing, thawing, storing, and transporting, with the container also being receivable in the supporting structure. The temperature control unit has a cavity for receiving the supporting structure, when the supporting structure supports the container, and the transportation cart has a channel for receiving the supporting structure, when the supporting structure supports the container.
摘要翻译：一种用于冷冻，解冻，运输和储存生物药物材料的系统，其包括容器，支撑结构，温度控制单元和运输车。容器适于容纳其中的生物药物用于冷冻，解冻，储存和运输，容器也可接收在支撑结构中。当支撑结构支撑容器时，温度控制单元具有用于接收支撑结构的空腔，并且当支撑结构支撑容器时，运输车具有用于接收支撑结构的通道。

8. 发明授权

US07228688B2 Scaled down freezing and thawing system for biopharmaceuticals and biologics 有权
标题翻译：缩小生物制药和生物制剂的冷冻和解冻系统
公开(公告)号：US07228688B2
公开(公告)日：2007-06-12
申请号：US10735378
申请日：2003-12-12
申请人： Nicolas Voute , Richard Wisniewski , Eric K. Lee , Jonathan N. Webb
发明人： Nicolas Voute , Richard Wisniewski , Eric K. Lee , Jonathan N. Webb
IPC分类号： F25D25/00 , F25D23/12 , F25D11/00
CPC分类号： A01N1/00 , F25D31/006 , F25D2331/809 , F25D2500/02 , F28D7/08 , F28F1/22 , G06F19/00
摘要： A freezing and thawing unit for small amounts of biopharmaceuticals and biologics. The freezing and thawing unit is reduced in scale, as compared to a corresponding commercial or large-scale process. The freezing and thawing unit can be used for testing, preservation and/or processing of small quantities of biopharmaceuticals and biologics.
摘要翻译：用于少量生物制药和生物制剂的冷冻和解冻装置。与相应的商业或大规模过程相比，冷冻和解冻单元的规模缩小。冷冻和解冻单元可用于测试，保存和/或加工少量生物药物和生物制剂。

9. 发明授权

US07137261B2 Systems and methods for freezing, mixing and thawing biopharmaceutical material 有权
标题翻译：用于冷冻，混合和解冻生物药物材料的系统和方法
公开(公告)号：US07137261B2
公开(公告)日：2006-11-21
申请号：US11085314
申请日：2005-03-21
申请人： David C. Brown , Jonathan Cutting , Eric K. Lee , Nicolas Voute , Brian J. Woodard
发明人： David C. Brown , Jonathan Cutting , Eric K. Lee , Nicolas Voute , Brian J. Woodard
IPC分类号： F25C1/00
CPC分类号： A01N1/02 , A01N1/0257 , A01N1/0263 , A01N31/02 , A23L3/364 , A23L3/365 , A61M1/0272 , A61M1/0277 , A61M1/0281 , F25B2600/07 , F25C1/04 , F25C2600/04 , F25D25/00 , F25D25/005 , F25D31/001 , F25D2331/8014 , F25D2400/20 , F25D2400/30 , G01N1/42 , A01N2300/00
摘要： A system for controlled freezing, storing and thawing of a biopharmaceutical material includes a cavity for receiving a container for holding the biopharmaceutical material. Further included are at least a pair of opposed surfaces facing the biopharmaceutical material holding container. At least one of the opposed surfaces includes a moveable contacting surface configured to contact the container to inhibit a clearance between the container and the movable contacting surface. Also included is at least one heat transfer surface which is thermally coupled to the biopharmaceutical material holding container when the moveable contacting surface contacts the container. Also, the cavity may be configured to receive a frame for supporting the container holding the biopharmaceutical material. Further, the system may include a driver to move the frame holding the container inside the cavity.
摘要翻译：用于受控冷冻，储存和解冻生物药物材料的系统包括用于容纳用于保持生物药物材料的容器的空腔。还包括面向生物药物材料保持容器的至少一对相对表面。相对表面中的至少一个包括可移动的接触表面，其构造成与容器接触以阻止容器和可动接触表面之间的间隙。还包括至少一个热传递表面，当可移动接触表面接触容器时，热传递表面热耦合到生物药物材料保持容器。此外，空腔可以被配置为容纳用于支撑容纳生物药物材料的容器的框架。此外，系统可以包括驱动器，以将保持容器的框架移动到腔体内。

10. 发明授权

US07104074B2 Systems and methods for freezing, storing, transporting and thawing biopharmaceutical material 有权
标题翻译：冷冻，储存，运输和解冻生物药物材料的系统和方法
公开(公告)号：US07104074B2
公开(公告)日：2006-09-12
申请号：US10455223
申请日：2003-06-04
申请人： Nicolas Voute , Eric K. Lee , James Edward DeBeers , Brian J. Woodward , Ngee Jenn Lee
发明人： Nicolas Voute , Eric K. Lee , James Edward DeBeers , Brian J. Woodward , Ngee Jenn Lee
IPC分类号： F25D15/00
CPC分类号： F25D25/005 , A01N1/00 , A01N1/02 , A01N1/0257 , A01N1/0263 , A01N31/02 , A23L3/364 , A23L3/365 , A61G12/001 , A61J1/165 , A61M1/0272 , A61M1/0277 , A61M1/0281 , A61M2209/084 , F25B2600/07 , F25D25/00 , F25D31/001 , F25D2331/801 , F25D2331/8014 , F25D2400/20 , F25D2400/30 , F25D2500/02 , Y10S165/919 , A01N2300/00
摘要： A system for freezing, thawing, transporting, and storing a biopharmaceutical material, which includes a container, a supporting structure, a temperature control unit, and a transportation cart. The container is adapted to receive the biopharmaceutical material therein for freezing, thawing, storing, and transporting, with the container also being receivable in the supporting structure. The temperature control unit has a cavity for receiving the supporting structure, when the supporting structure supports the container, and the transportation cart has a channel for receiving the supporting structure, when the supporting structure supports the container.
摘要翻译：一种用于冷冻，解冻，运输和储存生物药物材料的系统，其包括容器，支撑结构，温度控制单元和运输车。容器适于容纳其中的生物药物用于冷冻，解冻，储存和运输，容器也可接收在支撑结构中。当支撑结构支撑容器时，温度控制单元具有用于接收支撑结构的空腔，并且当支撑结构支撑容器时，运输车具有用于接收支撑结构的通道。

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