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1. 发明申请

US20100175393A1 Biomaterial Freezing 有权
标题翻译：生物材料冻结
公开(公告)号：US20100175393A1
公开(公告)日：2010-07-15
申请号：US12685952
申请日：2010-01-12
申请人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
发明人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
IPC分类号： F25D21/00 , B23P19/04 , F25B49/00 , G08B21/18
CPC分类号： F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
摘要翻译：本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。

2. 发明授权

US09833784B2 Feed bag construction 有权
公开(公告)号：US09833784B2
公开(公告)日：2017-12-05
申请号：US12818754
申请日：2010-06-18
申请人： Dennis Wong , Elias Noukas , Kristin Prescott , Brian Pereira , John Saragosa
发明人： Dennis Wong , Elias Noukas , Kristin Prescott , Brian Pereira , John Saragosa
IPC分类号： B65D33/00 , B01L3/00 , C12M1/00
CPC分类号： B01L3/523 , B01L3/502 , B01L3/505 , B01L2200/0689 , B01L2200/087 , B01L2300/042 , B01L2400/0633 , B65D33/00 , C12M99/00
摘要： A feed bag construction is provided comprising a feed bag, a first conduit sealed to the feed bag, a second conduit sealed to the interior of the feed bag for supplying wash reagent to the feed bag and a one piece cap that is removably mounted on the first conduit. The first conduit is provided with a hand operated butterfly valve to open or close the conduit.

3. 发明申请

US20110085746A1 FEED BAG CONSTRUCTION 有权
标题翻译：进料袋施工
公开(公告)号：US20110085746A1
公开(公告)日：2011-04-14
申请号：US12818754
申请日：2010-06-18
申请人： Dennis Wong , Elias Noukas , Kristin Prescott , Brian Pereira , John Saragosa
发明人： Dennis Wong , Elias Noukas , Kristin Prescott , Brian Pereira , John Saragosa
IPC分类号： B65D33/16
CPC分类号： B01L3/523 , B01L3/502 , B01L3/505 , B01L2200/0689 , B01L2200/087 , B01L2300/042 , B01L2400/0633 , B65D33/00 , C12M99/00
摘要： A feed bag construction is provided comprising a feed bag, a first conduit sealed to the feed bag, a second conduit sealed to the interior of the feed bag for supplying wash reagent to the feed bag and a one piece cap that is removably mounted on the first conduit. The first conduit is provided with a hand operated butterfly valve to open or close the conduit.
摘要翻译：提供了一种饲料袋结构，其包括进料袋，密封到进料袋的第一导管，密封到进料袋内部的第二导管，用于向进料袋供应洗涤剂，以及可拆卸地安装在进料袋上的单件盖第一条管道。第一个管道设有一个手动蝶阀以打开或关闭导管。

4. 发明授权

US08955340B2 Biocontainer with integrated temperature sensor 有权
标题翻译：具有集成温度传感器的生物容器
公开(公告)号：US08955340B2
公开(公告)日：2015-02-17
申请号：US12685952
申请日：2010-01-12
申请人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
发明人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
IPC分类号： F25D25/00 , B65B63/08 , F25D3/08 , F25D29/00 , A01N1/02
CPC分类号： F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
摘要翻译：本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。

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