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1. 发明申请

US20080091224A1 Apparatus and method for securing ocular tissue 失效
标题翻译：用于固定眼组织的装置和方法
公开(公告)号：US20080091224A1
公开(公告)日：2008-04-17
申请号：US11827444
申请日：2007-07-11
申请人： Jack Griffis , Mark Cox , Douglas Williamson , Gene Zdenek , Peter Richardson , Michael Smolek , Barrie Soloway , Rex Bare , Andrew Scherer , Timothy Payne
发明人： Jack Griffis , Mark Cox , Douglas Williamson , Gene Zdenek , Peter Richardson , Michael Smolek , Barrie Soloway , Rex Bare , Andrew Scherer , Timothy Payne
IPC分类号： A61F9/007
CPC分类号： A61F9/007 , A61B17/0231 , A61B17/30 , A61B2017/306 , A61B2017/308 , A61F2/14 , A61F9/013
摘要： Various ocular fixation devices are disclosed. One ocular fixation device includes first and second rings, where at least one of the rings includes means for fixating ocular tissue of an eye. The means for fixating are arranged to grasp the ocular tissue of the eye and to release the ocular tissue of the eye based on rotation of at least one of the first and second rings. The ocular fixation device may also include one or more structures on which a surgical tool can be mounted on the ocular fixation device at one or more locations. For instance, a dome of the ocular fixation device could include one or more holes that are configured to receive one or more projections from the surgical tool. As another example, a base of the ocular fixation device could include one or more notches configured to receive a projection from the surgical tool.
摘要翻译：公开了各种眼睛固定装置。一种眼睛固定装置包括第一和第二环，其中至少一个环包括用于固定眼睛的眼组织的装置。用于固定的装置布置成抓住眼睛的眼组织并且基于第一和第二环中的至少一个的旋转来释放眼睛的眼组织。眼睛固定装置还可以包括一个或多个结构，外科手术工具可以在其上一个或多个位置安装在眼睛固定装置上。例如，眼睛固定装置的圆顶可以包括被配置为从外科手术工具接收一个或多个突起的一个或多个孔。作为另一示例，眼睛固定装置的基底可以包括被配置为从外科手术工具接收突出物的一个或多个凹口。

2. 发明申请

US20070179161A1 Pyrazolopyrimidine compounds and their use in medicine 审中-公开
公开(公告)号：US20070179161A1
公开(公告)日：2007-08-02
申请号：US10551177
申请日：2004-03-18
申请人： Martin Parratt , Justin Bower , Douglas Williamson , Andrew Cansfield
发明人： Martin Parratt , Justin Bower , Douglas Williamson , Andrew Cansfield
IPC分类号： A61K31/519 , C07D487/02
CPC分类号： C07D487/04 , A61K31/519
摘要： Compounds of formula (I) or salts, N-oxides, hydrates or solvates thereof are inhibitors of kinase activity, and useful for the treatment of, for example, cancer, psoriasis or restenosis: wherein ring A is an optionally substituted carbocyclic or heterocyclic radical. Alk represents an optionally substituted divalent C1-C6 alkylene radical. n is 0 or 1. Q represents a radical of formula -(Alk1)p (X)r-(Alk2)s-Z wherein in any compatible combination Z is hydrogen or an optionally substituted carbocyclic or heterocyclic ring; Alk1 and Alk2 are optionally substituted divalent C1-C6 alkylene radicals which may contain a —O—, —S— or —NRA— link, wherein RA is hydrogen or C1-C6 alkyl; X represents —O—, —S—, —(C═O)—, —(C═S)—, —SO2—, —SO—, —C(═O)O—, —OC(═O)—, —C(═O)NRA—, —NR AC(═O)—, —C(═S)NRA, —NRAC(═S)—, —SO2NRA—, —NRASO2—, —OC(═O)NRA—, —NRAC(═O)O—, or —NRA— wherein RA is hydrogen or C1-C6 alkyl. p, r and s are independently 0 or 1. R1 represents a radical -(Alk3)a-(Y)b-(Alk4)d-B wherein a, b and d are independently 0 or 1; Alk3 and Alk4 are optionally substituted divalent C,-C3 alkylene radicals; Y represents a monocyclic divalent carbocyclic or heterocyclic radical having from 5 to 8 ring atoms, —O—, —S—, or —NRA— wherein RA is hydrogen or C1-C6 alkyl; B represents hydrogen or halo, or an optionally substituted monocyclic carbocyclic or heterocyclic ring having from 5 to 8 ring atoms, or in the case where Y is —NRA— and b is 1, then RA and the radical -(Alk4)d-B taken together with the nitrogen to which they are attached may form an optionally substituted heterocyclic ring. R represents hydrogen, halo, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, phenyl, benzyl, cycloalkyl with 3 to 6 ring atoms, or a monocyclic heterocyclic group having 5 or 6 ring atoms.

3. 发明授权

US6032588A Convertible table system 失效
标题翻译：可转换表系统
公开(公告)号：US6032588A
公开(公告)日：2000-03-07
申请号：US147286
申请日：1998-11-20
申请人： Paul Douglas Williamson , Bernard Anton Hiestand , Peter John Wilcock
发明人： Paul Douglas Williamson , Bernard Anton Hiestand , Peter John Wilcock
IPC分类号： A47B1/04 , A47B13/02
CPC分类号： A47B13/023 , A47B1/04
摘要： There is described a convertible table system which has a fixed central portion and leaves along at least two adjacent edges. The leaves fold from an operative position where they are substantially co-planar with the table top to a stored position where they are rotated through 180.degree. to be against or adjacent the bottom of the fixed part of the table. The leaves are retained in the operative position by sliding supports. These supports have pendant portions to be sufficiently robust to withstand the usage to which the table might be put. The pendant portions are able to be retracted out of the paths of the leaves when they are folded to the stored position. The angle of mounting of the sliding supports allows this to occur. The leaves are held in the stored position by a catch which can be magnetic or frictional or other.
摘要翻译： PCT No.PCT / NZ98 / 00137 Sec。 371日期：1998年11月20日 102（e）1998年11月20日日期PCT提交1998年9月14日PCT公布。第WO99 / 13753号公报日期1999年3月25日描述了具有固定中心部分并沿至少两个相邻边缘离开的可转换台系统。叶片从操作位置折叠，其中它们与台面基本共面，到存储位置，在那里它们被旋转180度以抵靠或邻近桌子的固定部分的底部。叶片通过滑动支撑件保持在操作位置。这些支撑件具有足够坚固的侧壁部分以承受桌子可能被使用的使用。当折叠到存储位置时，悬挂部分能够从叶片的路径中缩回。滑动支架的安装角度允许发生这种情况。叶子通过可以是磁性或摩擦力的捕获物保持在存储位置。

4. 发明申请

US20080091266A1 Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods 有权
标题翻译：用于治疗老花眼和其他眼睛疾病的巩膜假体及相关装置和方法
公开(公告)号：US20080091266A1
公开(公告)日：2008-04-17
申请号：US11827382
申请日：2007-07-11
申请人： Jack Griffis , Mark Cox , Douglas Williamson , Gene Zdenek , Peter Richardson , Michael Smolek , Barrie Soloway , Rex Bare , Andrew Scherer , Timothy Payne
发明人： Jack Griffis , Mark Cox , Douglas Williamson , Gene Zdenek , Peter Richardson , Michael Smolek , Barrie Soloway , Rex Bare , Andrew Scherer , Timothy Payne
IPC分类号： A61F2/14
CPC分类号： A61F2/147 , A61F2/148 , A61F2210/0023
摘要： One example scleral prosthesis includes a first free end and a second free end, each wider than a middle portion of the scleral prosthesis. Multiple first portions form the first end of the scleral prosthesis. The first portions are separated along at least half of a length of the scleral prosthesis. Multiple second portions may form the second end of the scleral prosthesis, and the second portions may be separated along less than a quarter of the length of the scleral prosthesis. An implantation device can be used to facilitate implantation of a scleral prosthesis. The implantation device includes a first end portion configured to be inserted into a scleral tunnel of an eye. The implantation device also includes a second end portion configured to receive the scleral prosthesis. A rod with a tapered and rounded end can be partially inserted into the first end portion of the implantation device.
摘要翻译：一个例子是巩膜假体包括第一自由端和第二自由端，每个宽度大于巩膜假体的中间部分。多个第一部分形成巩膜假体的第一端。第一部分沿巩膜假体长度的至少一半分开。多个第二部分可以形成巩膜假体的第二端，并且第二部分可以沿着巩膜假体的长度的小于四分之一分开。可以使用植入装置来促进巩膜假体的植入。植入装置包括构造成插入到眼睛的巩膜隧道中的第一端部。植入装置还包括构造成接收巩膜假体的第二端部。具有锥形和圆形端的杆可以部分地插入植入装置的第一端部。

5. 发明申请

US20070275961A1 Triazolo ' 1, 5-A ! Pyrimidines and Their Use in Medicine 审中-公开
标题翻译： Triazolo'1，5-A！嘧啶及其在医学中的应用
公开(公告)号：US20070275961A1
公开(公告)日：2007-11-29
申请号：US10558694
申请日：2004-06-02
申请人： Justin Bower , Andrew Cansfield , Allan Jordan , Martin Parratt , Lee Walmsley , Douglas Williamson
发明人： Justin Bower , Andrew Cansfield , Allan Jordan , Martin Parratt , Lee Walmsley , Douglas Williamson
IPC分类号： A61K31/519 , A61K31/496 , A61K31/5377 , A61P17/06 , A61P35/00 , A61P9/00 , C07D413/14 , C07D487/04
CPC分类号： A61K31/519 , C07D487/04
摘要： Compounds of formula (IA) or (AB) are kinase inhibitors, especially of CDK2, and/or PDK1 and/or CHK1: wherein Ring A is an optionally substituted aryl, heteroaryl, carbocyclic or heterocyclic radical, Alk represents an optionally substituted clivaient C1-C6 alkylene radical; n is 0 or 1; Q represents a radical of formula -(Alk1)p-(X),(Alk2)s-Z wherein in any compatible combination Z is hydrogen or an optionally substituted carbocyclic or heterocyclic ring, p, r and s are 0 or 1, and Alk1, Alk2, X, are as described in the specification, and R1 represents a radical 3 4 3 (CYC)k-(Alk3)a-(Y)b-(Alk4)d-B wherein k, a, b and d are 0 or 1, and Cyc, Alk3, Alk4 and B are as described in the specification.
摘要翻译：式（IA）或（AB）的化合物是激酶抑制剂，特别是CDK2和/或PDK1和/或CHK1的激酶抑制剂：其中环A是任选取代的芳基，杂芳基，碳环或杂环基，Alk表示任选取代的亲水性C C 1 -C 6亚烷基; n为0或1; Q表示式 - （Alk-1）对 - （X），（Alk 2 O 3）-SZ的基团，其中以任何相容的组合 Z是氢或任选取代的碳环或杂环，p，r和s是0或1，并且Alk 1，Alk 2 X，如规格，R 1表示基团3 4 3（CYC）3 - （烷基）（Y）b - 其中k，a，b和d分别为0或1，并且Cyc，Alk 3号，3号，4号和B号如说明书中所述。

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