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1. 发明申请

US20090203940A1 Method for preparing 4-[2-(dimethylamino)ethoxy]benzylamine as itopride-hydrocloride salt mediate 审中-公开
标题翻译：制备4- [2-（二甲基氨基）乙氧基]苄胺的噻吩并 - 氢氯酸盐的方法
公开(公告)号：US20090203940A1
公开(公告)日：2009-08-13
申请号：US11658746
申请日：2004-09-15
申请人： Dong Yeon Kim , Jae G. Kim , Dae Jin Cho , Gong Y. Lee , Hong Y. Kim , Seok H. Woo
发明人： Dong Yeon Kim , Jae G. Kim , Dae Jin Cho , Gong Y. Lee , Hong Y. Kim , Seok H. Woo
IPC分类号： C07C213/06
CPC分类号： C07C213/06 , C07C213/00 , C07C217/58
摘要： The present invention relates to a novel method for preparing an itopride-hydrochloride mediate of the formula 1, which is useful for digestive tract activator, and more particularly, the present invention provides with a method for preparing 4-[2-(dimethylamino)ethoxy]benzylamine of the formula 1, an itopride-hydrochloride mediate, whereby being capable of manufacturing in a high yield and lowering cost through a simple purification and a selective reaction, and the method is harmless and safe to human and environment due to not generating toxic gas. And specially, a super-high pressure hydrogenation and a reduction reaction using a metal catalyst are not carried out, therefore, it is very safe method, and also special manufacturing equipments are not needed.
摘要翻译：本发明涉及一种制备式1的伊曲肽 - 盐酸盐介质的新方法，其可用于消化道活化剂，更具体地说，本发明提供了制备4- [2-（二甲基氨基）乙氧基 ]苄胺，盐酸伊必利德介导，其通过简单的纯化和选择性反应能够以高产率制造并降低成本，并且该方法由于不产生有毒物质而对人和环境无害和安全加油站。特别是使用金属催化剂进行超高压氢化和还原反应不能进行，因此是非常安全的方法，也不需要特殊的制造设备。

2. 发明授权

US09532178B2 Location management system 有权
标题翻译：位置管理系统
公开(公告)号：US09532178B2
公开(公告)日：2016-12-27
申请号：US14391457
申请日：2013-03-25
申请人： Dong-Yeon Kim , Jeong-Yong Pyo
发明人： Dong-Yeon Kim , Jeong-Yong Pyo
IPC分类号： H04W24/00 , H04W4/02 , G01S5/02 , H04W64/00 , H04W4/00 , H04W88/04 , H04W88/06 , H04W4/22
CPC分类号： H04W4/028 , G01S5/02 , H04W4/029 , H04W4/80 , H04W4/90 , H04W64/00 , H04W88/04 , H04W88/06
摘要： A location management system includes: user equipment that periodically repeats an operating state and a standby state with a predetermined time interval, transmits a short-range wireless communication signal including its own identification information; a user equipment managing server that collects and manages user management information including the identification information of the user equipment and manager information of a manager who manages the management target and that monitors and provides location information of the management target, the location of which needs to be monitored, to the manager; and a location information relay terminal that stores identification information of a signal previously transmitted from the user equipment and that provides the acquired location information and time information along with the identification information to the user equipment managing server when both pieces of information agree to each other.
摘要翻译：位置管理系统包括：以预定的时间间隔周期性地重复操作状态和待机状态的用户设备，发送包括其自己的识别信息的短距离无线通信信号; 收集和管理用户管理信息的用户设备管理服务器，包括用户设备的识别信息和管理管理目标的管理者的管理者信息，并监视和提供管理对象的位置信息，其位置需要监督，经理; 以及位置信息中继终端，其存储先前从用户设备发送的信号的识别信息，并且当两条信息彼此一致时，将所获取的位置信息和时间信息连同识别信息一起提供给用户设备管理服务器。

3. 发明申请

US20140031364A1 PHENYL-ISOXAZOL DERIVATIVES AND PREPARATION PROCESS THEREOF 有权
标题翻译：苯丙酸衍生物及其制备方法
公开(公告)号：US20140031364A1
公开(公告)日：2014-01-30
申请号：US13979743
申请日：2012-03-30
申请人： Dong Yeon Kim , Dae Jin Cho , Gong Yeal Lee , Hong Youb Kim , Seok Hun Woo , Hae Un Lee , Sung Moo Kim , Choong Am Ahn , Seung Bin Yoon
发明人： Dong Yeon Kim , Dae Jin Cho , Gong Yeal Lee , Hong Youb Kim , Seok Hun Woo , Hae Un Lee , Sung Moo Kim , Choong Am Ahn , Seung Bin Yoon
IPC分类号： A61K31/496 , A61K31/454 , A61K45/06 , C07D413/06 , C07D261/18 , A61K31/42
CPC分类号： A61K31/496 , A61K31/42 , A61K31/454 , A61K45/06 , C07D261/08 , C07D261/18 , C07D413/06
摘要： Disclosed are a phenyl-isoxazol derivative compound, which is useful as a treatment material for virus infection, especially, infection of an influenza virus, or its pharmaceutically acceptable derivative, a preparation method thereof, and an illness treatment pharmaceutical composition including the compound as an active ingredient.
摘要翻译：公开了苯并异恶唑衍生物化合物，其可用作病毒感染的治疗材料，特别是感染流感病毒或其药学上可接受的衍生物，其制备方法和疾病治疗药物组合物，其包含该化合物作为有效成分。

4. 发明授权

US07501424B2 N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof 有权
标题翻译： N-苯基-2-嘧啶 - 胺衍生物及其制备方法
公开(公告)号：US07501424B2
公开(公告)日：2009-03-10
申请号：US11813175
申请日：2005-09-07
申请人： Dong-Yeon Kim , Dae-Jin Cho , Gong-Yeal Lee , Hong-Youb Kim , Seok-Hun Woo , Yong-Seok Kim , Sun-Ahe Lee , Byoung-Cheol Han
发明人： Dong-Yeon Kim , Dae-Jin Cho , Gong-Yeal Lee , Hong-Youb Kim , Seok-Hun Woo , Yong-Seok Kim , Sun-Ahe Lee , Byoung-Cheol Han
IPC分类号： C07D239/28 , A61K31/505
CPC分类号： C07D417/14 , C07D401/14 , C07D403/14
摘要： The present invention relates to a novel N-phenyl-2-pyrimidine-amine derivative represented by the above formula (1) and its salt showing a superior effect on cancer in warm-blooded animals, such as lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or acute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer, cervical cancer, lymphoma, etc. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various diseases, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.
摘要翻译：本发明涉及由上述式（1）表示的新型N-苯基-2-嘧啶胺衍生物及其对温血动物（例如肺癌，胃癌，结肠癌）中对癌症的显着影响的盐，胰腺癌，肝癌，前列腺癌，乳腺癌，慢性或急性白血病，血液恶性肿瘤，脑病，膀胱癌，直肠癌，子宫颈癌，淋巴瘤等。本发明还涉及一种制备该化合物的方法，用于治疗上述各种疾病的药物组合物，其包含有效量的作为活性成分的化合物以及药学上可接受的惰性载体。

5. 发明授权

US5703097A 5-pyrrolyl-2-pyridylmethylsulfinyl benzimidazole derivatives 失效
标题翻译： 5-吡咯基-2-吡啶基甲基亚磺酰基苯并咪唑衍生物
公开(公告)号：US5703097A
公开(公告)日：1997-12-30
申请号：US537846
申请日：1995-10-20
申请人： Su Ung Kim , Dong Yeon Kim , Gi ju Chung , Sung Kol Hong , Sung Jun Park , Sang Hoon Nam , Yong Suk Lee
发明人： Su Ung Kim , Dong Yeon Kim , Gi ju Chung , Sung Kol Hong , Sung Jun Park , Sang Hoon Nam , Yong Suk Lee
IPC分类号： C07D401/14 , A61K31/402 , A61K31/4184 , A61K31/44 , A61K31/4427 , A61P1/04 , A61P43/00 , G11B15/02 , C07D401/12
CPC分类号： C07D401/14
摘要： The present invention relates to a novel compound 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazole derivative having general formula (I) and its salt, ##STR1## wherein all variables are as defined in the specification. The present invention also relates to a process for preparation of the compound of formula (I), as defined above, and its use as an anti-ulcer agent.
摘要翻译： PCT No.PCT / KR94 / 00098 Sec。 371 1995年10月20日第 102（e）日期1995年10月20日PCT 1994年7月22日PCT公布。公开号WO95 / 23140 PCT 日期：1995年8月31日本发明涉及具有通式（I）的新化合物5-吡咯基-2-吡啶基甲基亚磺酰基苯并咪唑衍生物及其盐，其中所有变量如说明书中所定义。本发明还涉及如上定义的式（I）化合物的制备方法及其作为抗溃疡剂的用途。

6. 发明授权

US09132126B2 Phenyl-isoxazole derivatives and preparation process thereof 有权
标题翻译：苯基异恶唑衍生物及其制备方法
公开(公告)号：US09132126B2
公开(公告)日：2015-09-15
申请号：US13979743
申请日：2012-03-30
申请人： Dong Yeon Kim , Dae Jin Cho , Gong Yeal Lee , Hong Youb Kim , Seok Hun Woo , Hae Un Lee , Sung Moo Kim , Choong Am Ahn , Seung Bin Yoon
发明人： Dong Yeon Kim , Dae Jin Cho , Gong Yeal Lee , Hong Youb Kim , Seok Hun Woo , Hae Un Lee , Sung Moo Kim , Choong Am Ahn , Seung Bin Yoon
IPC分类号： C07D261/14 , C07D261/18 , C07D413/06 , A61K31/496 , C07D261/08 , A61K31/42 , A61K31/454 , A61K45/06
CPC分类号： A61K31/496 , A61K31/42 , A61K31/454 , A61K45/06 , C07D261/08 , C07D261/18 , C07D413/06
摘要： Disclosed are a phenyl-isoxazol derivative compound, which is useful as a treatment material for virus infection, especially, infection of an influenza virus, or its pharmaceutically acceptable derivative, a preparation method thereof, and an illness treatment pharmaceutical composition including the compound as an active ingredient.
摘要翻译：公开了苯并异恶唑衍生物化合物，其可用作病毒感染的治疗材料，特别是感染流感病毒或其药学上可接受的衍生物，其制备方法和疾病治疗药物组合物，其包含该化合物作为有效成分。

7. 发明授权

US08216589B2 HBV vaccine and a process of preparing the same 有权
标题翻译： HBV疫苗及其制备方法
公开(公告)号：US08216589B2
公开(公告)日：2012-07-10
申请号：US12225341
申请日：2008-01-28
申请人： Jung Sun Yum , Byung Cheol Ahn , Hyun Jin Jo , Dong Yeon Kim , Joo Youn Lee , Ki Hyun Kim , Jae Seung Yoon , Hong Mo Moon
发明人： Jung Sun Yum , Byung Cheol Ahn , Hyun Jin Jo , Dong Yeon Kim , Joo Youn Lee , Ki Hyun Kim , Jae Seung Yoon , Hong Mo Moon
IPC分类号： A61K39/29 , C12N15/09 , C12N5/10 , C12N1/21 , C12N15/63
CPC分类号： A61K39/292 , A61K39/12 , A61K2039/5258 , A61K2039/545 , A61K2039/55505 , A61K2039/57 , C07K14/005 , C12N2730/10122 , C12N2730/10134
摘要： The present invention relates to an HBV vaccine comprising an entire hepatitis B surface antigen of L protein, M protein and S protein, in which the produced antigens form virus-like particles, and a multi-antigen vaccine further comprising an HBV core antigen in addition to the entire surface antigen, and a method for preparing the same. The vaccines provide various epitopes and have excellent immunogenicity to induce a strong humoral immune response as well as a cell-mediated immune response.
摘要翻译：本发明涉及包含产生的抗原形成病毒样颗粒的L蛋白，M蛋白和S蛋白的全部乙型肝炎表面抗原的HBV疫苗，以及进一步包含HBV核心抗原的多抗原疫苗到整个表面抗原，及其制备方法。疫苗提供各种表位并且具有优异的免疫原性以诱导强的体液免疫应答以及细胞介导的免疫应答。

8. 发明授权

US07595323B2 N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof 失效
标题翻译： N-苯基-2-嘧啶 - 胺衍生物及其制备方法
公开(公告)号：US07595323B2
公开(公告)日：2009-09-29
申请号：US10806834
申请日：2004-03-22
申请人： Dong-Yeon Kim , Jae-Gun Kim , Dae-Jin Cho , Gong-Yeal Lee , Hong-Youb Kim , Seok-Hun Woo , Yong-Seok Kim , Woo-Chul Bae , Sun-Ahe Lee , Byoung-Cheol Han
发明人： Dong-Yeon Kim , Jae-Gun Kim , Dae-Jin Cho , Gong-Yeal Lee , Hong-Youb Kim , Seok-Hun Woo , Yong-Seok Kim , Woo-Chul Bae , Sun-Ahe Lee , Byoung-Cheol Han
IPC分类号： C07D239/28 , A61K31/505
CPC分类号： C07D401/04 , C07D401/12
摘要： The present invention relates to an N-phenyl-2-pyrimidine-amine derivative showing a superior effect on lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or acute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer, or cervical cancer, etc. of warm-blooded animals and its salt. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various diseases, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.
摘要翻译：本发明涉及对肺癌，胃癌，结肠癌，胰腺癌，肝癌，前列腺癌，乳腺癌，慢性或急性白血病，血液恶性肿瘤，脑病等有显着影响的N-苯基-2-嘧啶胺衍生物，膀胱癌，直肠癌或子宫颈癌等，其温血动物及其盐。本发明还涉及一种制备该化合物的方法以及用于治疗上述各种疾病的药物组合物，其包含有效量的作为活性成分的化合物以及药学上可接受的惰性载体。

9. 发明授权

US07299305B2 Apparatus and method for indicating connection state of input/output cable 有权
标题翻译：用于指示输入/输出电缆的连接状态的装置和方法
公开(公告)号：US07299305B2
公开(公告)日：2007-11-20
申请号：US10729998
申请日：2003-12-09
申请人： Dong-yeon Kim
发明人： Dong-yeon Kim
IPC分类号： G06F13/10 , G06F15/177
CPC分类号： G06F3/0659 , G06F3/0605 , G06F3/0632 , G06F3/0653 , G06F3/0677
摘要： An apparatus and method for indicating the connection state of an input/output cable between an ATAPI drive and a host. The apparatus includes an indicator and a controller. The indicator is a communication device between an AT Attachment Packet Interface (ATAPI) drive and a host interconnected via the input/output cable and indicates in response to a control signal whether the AT Attachment Packet Interface (ATAPI) drive is connected to or disconnected from the host via the input/output cable. The controller sets a flag to check the connection state of the input/output cable, when power is applied to the AT Attachment Packet Interface (ATAPI) drive, and outputs the control signal to the indicator to indicate that the input/output cable is not connected to the host when a command is not received from the host for a predetermined period of time.
摘要翻译：一种用于指示ATAPI驱动器和主机之间的输入/输出电缆的连接状态的装置和方法。该装置包括指示器和控制器。指示器是AT附件分组接口（ATAPI）驱动器和通过输入/输出电缆互连的主机之间的通信设备，并且响应于控制信号指示AT附件分组接口（ATAPI）驱动器是连接到还是断开主机通过输入/输出电缆。控制器设置一个标志，以检查输入/输出电缆的连接状态，当AT附件分组接口（ATAPI）驱动器接通电源时，控制信号输出到指示灯，以指示输入/输出电缆不是当没有从主机接收到预定时间段的命令时连接到主机。

10. 发明申请

US20150080018A1 LOCATION MANAGEMENT SYSTEM 审中-公开
标题翻译：位置管理系统
公开(公告)号：US20150080018A1
公开(公告)日：2015-03-19
申请号：US14391457
申请日：2013-03-25
申请人： Dong-Yeon KIM , Jeong-Yong PYO
发明人： Dong-Yeon Kim , Jeong-Yong Pyo
IPC分类号： H04W4/02 , H04W4/00
CPC分类号： H04W4/028 , G01S5/02 , H04W4/029 , H04W4/80 , H04W4/90 , H04W64/00 , H04W88/04 , H04W88/06
摘要： A location management system includes: user equipment that periodically repeats an operating state and a standby state with a predetermined time interval, transmits a short-range wireless communication signal including its own identification information; a user equipment managing server that collects and manages user management information including the identification information of the user equipment and manager information of a manager who manages the management target and that monitors and provides location information of the management target, the location of which needs to be monitored, to the manager; and a location information relay terminal that stores identification information of a signal previously transmitted from the user equipment and that provides the acquired location information and time information along with the identification information to the user equipment managing server when both pieces of information agree to each other.
摘要翻译：位置管理系统包括：以预定的时间间隔周期性地重复操作状态和待机状态的用户设备，发送包括其自己的识别信息的短距离无线通信信号; 收集和管理用户管理信息的用户设备管理服务器，包括用户设备的识别信息和管理管理目标的管理者的管理者信息，并监视和提供管理对象的位置信息，其位置需要监督，经理; 以及位置信息中继终端，其存储先前从用户设备发送的信号的识别信息，并且当两条信息彼此一致时，将所获取的位置信息和时间信息连同识别信息一起提供给用户设备管理服务器。

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