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1. 发明授权

US06406846B1 Method for determining whether a human patient is susceptible to hereditary pancreatitis, and primers therefore 失效
标题翻译：确定人类患者是否易患遗传性胰腺炎的方法，以及引物
公开(公告)号：US06406846B1
公开(公告)日：2002-06-18
申请号：US08949344
申请日：1997-10-14
申请人： David Whitcomb , Garth D. Ehrlich , Michael C. Gorry
发明人： David Whitcomb , Garth D. Ehrlich , Michael C. Gorry
IPC分类号： C12Q0168
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： A method for determining whether a human patient is susceptible to hereditary pancreatitis. The method comprises the steps of obtaining nucleic acid from the human patient. Then there is the step of checking the nucleic acid for a mutation that indicates hereditary pancreatitis. A primer which reacts with a human trypsinogen gene to identify hereditary pancreatitis. A method for detecting in a human a mutation in a trypsinogen gene indicative of hereditary pancreatitis. The invention comprises the steps of obtaining a sample having DNA of the patient. Then there is the step of processing the sample so the DNA will be recognized by a desired restriction enzyme. Next there is the step of introducing the desired restriction enzyme to the DNA wherein the recognizing of the desired restriction enzyme to the DNA indicates the presence of the mutation.
摘要翻译：一种确定人类患者是否易患遗传性胰腺炎的方法。该方法包括从人类患者获得核酸的步骤。然后有检查核酸的突变指示遗传性胰腺炎的步骤。与人胰蛋白酶原基因反应以鉴定遗传性胰腺炎的引物。一种在人类中检测指示遗传性胰腺炎的胰蛋白酶原基因突变的方法。本发明包括获得具有患者DNA的样品的步骤。然后是处理样品的步骤，使得DNA将被期望的限制酶识别。接下来，将所需的限制酶引入到DNA中，其中识别所需的限制性内切酶的DNA表明存在突变。

2. 发明授权

US07337683B2 Insitu inertial particulate separation system 有权
标题翻译：本体惯性颗粒分离系统
公开(公告)号：US07337683B2
公开(公告)日：2008-03-04
申请号：US11116996
申请日：2005-04-27
申请人： Herbert H. DeFriez , Clifford Gordon , David Whitcomb , Joseph Gregoria
发明人： Herbert H. DeFriez , Clifford Gordon , David Whitcomb , Joseph Gregoria
IPC分类号： G01N1/00
CPC分类号： G01N1/2258 , G01N1/2205 , G01N1/2208 , G01N2001/227
摘要： A sampling system for separating gaseous samples from a gas stream containing particulate matter and transporting the gaseous samples to a location outside of the flowing gas stream comprises an inertial filter mounted on the end of a hollow probe, the inertial filter positioned within the flowing gaseous stream. The inertial filter comprises a filter media mounted within a tube such that a portion of the particulate-containing gaseous steam flows through an annular space between the filter media and the tube wall, the gas to be sampled passes through the filter media into an inner space and the filtered gas is then delivered through the hollow probe to analytical devices external to the space containing the flowing gas stream, such as a flue stack.
摘要翻译：用于从含有颗粒物质的气流中分离气态样品并将气态样品输送到流动气流外部的位置的采样系统包括安装在中空探针的端部上的惯性过滤器，该惯性过滤器位于流动气流。惯性过滤器包括安装在管内的过滤介质，使得一部分含颗粒的气态蒸汽流过过滤介质和管壁之间的环形空间，待采样的气体通过过滤介质进入内部空间然后将经过过滤的气体通过中空探针输送到包含流动气体流的空间（例如烟道叠层）之外的分析装置。

3. 发明申请

US20050123871A1 Method for chemical sensitization of silver halide for photothermographic use 失效
标题翻译：用于光热照相术的卤化银化学增感方法
公开(公告)号：US20050123871A1
公开(公告)日：2005-06-09
申请号：US10731462
申请日：2003-12-09
申请人： Lilia Burleva , Kumars Sakizadeh , David Whitcomb , Sharon Simpson
发明人： Lilia Burleva , Kumars Sakizadeh , David Whitcomb , Sharon Simpson
IPC分类号： G03C1/09 , G03C1/498 , G03C5/16
CPC分类号： G03C1/49845 , G03C1/09 , Y10S430/151 , Y10S430/161
摘要： A photothermographic emulsion is prepared by chemically sensitizing silver halide grains formed by oxidative decomposition of a diphenylphosphine sulfide compound on or around the silver halide grains. This procedure uses a unique sequence of steps and provides increased photographic speed and manufacturing reproducibility.
摘要翻译：通过化学增感由卤化银颗粒上或周围的二苯基硫化膦化合物氧化分解形成的卤化银颗粒来制备光热敏成像乳液。该方法使用独特的步骤顺序并提供增加的照相速度和制造再现性。

4. 发明申请

US20070015660A1 Direct thermographic materials with catechol borate reducing agents 失效
公开(公告)号：US20070015660A1
公开(公告)日：2007-01-18
申请号：US11183609
申请日：2005-07-18
申请人： Kumars Sakizadeh , Peter Cowdery-Corvan , Leif Olson , David Whitcomb
发明人： Kumars Sakizadeh , Peter Cowdery-Corvan , Leif Olson , David Whitcomb
IPC分类号： B41M5/20
CPC分类号： G03C1/49872 , G03C1/32 , G03C1/49827 , G03C1/4989 , G03C1/85 , G03C2001/7628
摘要： Non-photosensitive direct thermographic materials comprise a reducing agent that is a catechol borate compound. These compounds can reduce silver(I) ion to metallic silver to produce a dense black silver image under the short time and high temperature conditions that occur when using thermal print-heads during direct thermal printing.

5. 发明申请

US20060128566A1 Direct thermographic materials with phenolic reducing agents 失效
公开(公告)号：US20060128566A1
公开(公告)日：2006-06-15
申请号：US11012788
申请日：2004-12-15
申请人： David Whitcomb , Leif Olson , Peter Cowdery-Corvan , Kumars Sakizadeh , Takuzo Ishida
发明人： David Whitcomb , Leif Olson , Peter Cowdery-Corvan , Kumars Sakizadeh , Takuzo Ishida
IPC分类号： B41M5/20
CPC分类号： G03C1/49827 , G03C1/49872 , G03C1/4989 , G03C2001/7635
摘要： Non-photosensitive direct thermographic materials comprise a reducing agent that is a specific ortho-amino-phenol, para-amino-phenol, or hydroquinone compound. These compounds can reduce silver(I) ion to metallic silver to produce a dense black silver image under the short time and high temperature conditions that occur when using thermal print-heads during direct thermal printing. The materials are characterized by their calculated aqueous deprotonation and their calculated anion HOMO energies.

6. 发明申请

US20050241416A1 Insitu inertial particulate separation system 有权
标题翻译：本体惯性颗粒分离系统
公开(公告)号：US20050241416A1
公开(公告)日：2005-11-03
申请号：US11116996
申请日：2005-04-27
申请人： Herbert DeFriez , Clifford Gordon , David Whitcomb , Joseph Gregoria
发明人： Herbert DeFriez , Clifford Gordon , David Whitcomb , Joseph Gregoria
IPC分类号： G01N1/00 , G01N1/22
CPC分类号： G01N1/2258 , G01N1/2205 , G01N1/2208 , G01N2001/227
摘要： A sampling system for separating gaseous samples from a gas stream containing particulate matter and transporting the gaseous samples to a location outside of the flowing gas stream comprises an inertial filter mounted on the end of a hollow probe, the inertial filter positioned within the flowing gaseous stream. The inertial filter comprises a filter media mounted within a tube such that a portion of the particulate-containing gaseous steam flows through an annular space between the filter media and the tube wall, the gas to be sampled passes through the filter media into an inner space and the filtered gas is then delivered through the hollow probe to analytical devices external to the space containing the flowing gas stream, such as a flue stack.
摘要翻译：用于从含有颗粒物质的气流中分离气态样品并将气态样品输送到流动气流外部的位置的采样系统包括安装在中空探针的端部上的惯性过滤器，该惯性过滤器位于流动气流。惯性过滤器包括安装在管内的过滤介质，使得一部分含粒状气体蒸汽流过过滤介质和管壁之间的环形空间，待采样的气体通过过滤介质进入内部空间然后将经过过滤的气体通过中空探针输送到包含流动气体流的空间（例如烟道叠层）之外的分析装置。

7. 发明申请

US20050095540A1 Thermally developable imaging materials with barrier layer 失效
标题翻译：具有阻隔层的可热成像成像材料
公开(公告)号：US20050095540A1
公开(公告)日：2005-05-05
申请号：US10699768
申请日：2003-11-03
申请人： Kumars Sakizadeh , Karissa Eckert , Gary LaBelle , David Whitcomb
发明人： Kumars Sakizadeh , Karissa Eckert , Gary LaBelle , David Whitcomb
IPC分类号： G03C1/46 , G03C1/498 , G03C1/00
CPC分类号： G03C1/49872 , G03C1/04 , G03C1/46 , G03C1/498 , G03C1/49818 , G03C1/49845 , G03C1/49863 , G03C1/49881 , G03C5/164 , G03C2001/7635 , Y10S430/162
摘要： Thermographic and photothermographic materials comprise a barrier layer to provide physical protection and to prevent migration of diffusible imaging components and by-products resulting from high temperature imaging and/or development. The barrier layer comprises a scavenger that is a metal hydroxide or ester. This barrier layer is capable of retarding diffusion of mobile chemicals such as organic carboxylic acids, developers, and toners.
摘要翻译：热成像和光热成像材料包括阻挡层，以提供物理保护并防止可扩散成像组件和由高温成像和/或显影产生的副产物的迁移。阻挡层包含作为金属氢氧化物或酯的清除剂。该阻挡层能够阻止移动化学品如有机羧酸，显影剂和调色剂的扩散。

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