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    • 3. 发明授权
    • Endoluminal delivery of anesthesia
    • 腔内输送麻醉
    • US08308709B2
    • 2012-11-13
    • US13017905
    • 2011-01-31
    • David W. Chang
    • David W. Chang
    • A61M31/00
    • A61M19/00A61B6/487A61B18/1492A61M5/007A61M25/0084A61M25/04A61M25/10A61M25/1011A61M2025/009A61M2210/12
    • Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.
    • 本文描述的是用于从血管内选择性地将流体(特别是麻醉剂)施用于目标组织的方法和装置,同时最小化施加于非目标组织的流体的量。 本文所述的注射导管可以包括细长体,定向注射器和用于在延伸注射器之前固定导管的一个或多个保持架。 将麻醉剂选择性地施加到目标结构的方法通常包括将注射导管插入体容器中的步骤,将注射导管定位在体内容器中靠近靶结构的位置,在将注射导管从注射导管 并将注射导管的麻醉剂施加到目标结构上。
    • 6. 发明授权
    • Endoluminal delivery of anesthesia
    • 腔内输送麻醉
    • US07879011B2
    • 2011-02-01
    • US11282222
    • 2005-11-18
    • David W. Chang
    • David W. Chang
    • A61M1/00A61M5/178A61M29/00
    • A61M19/00A61B6/487A61B18/1492A61M5/007A61M25/0084A61M25/04A61M25/10A61M25/1011A61M2025/009A61M2210/12
    • Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.
    • 本文描述的是用于从血管内选择性地将流体(特别是麻醉剂)施用于目标组织的方法和装置,同时最小化施加于非目标组织的流体的量。 本文所述的注射导管可以包括细长体,定向注射器和用于在延伸注射器之前固定导管的一个或多个保持架。 将麻醉剂选择性地施加到目标结构的方法通常包括将注射导管插入体容器中的步骤,将注射导管定位在体内容器中靠近靶结构的位置,在将注射导管从注射导管 并将注射导管的麻醉剂施加到目标结构上。
    • 7. 发明申请
    • Method and apparatus for vascular access
    • 用于血管通路的方法和装置
    • US20080243080A1
    • 2008-10-02
    • US12072683
    • 2008-05-16
    • David W. Chang
    • David W. Chang
    • A61M5/178A61B17/08A61M29/00
    • A61M25/01A61B17/3423
    • A method and apparatus is described that facilitates appropriate placement of a closure device and allows ease of placement with repeated access without bleeding. A suitable biocompatible polymer diaphragm such as silicone or nipple is place on the adventitia of the vessel through a small cutdown incision. The puncture surface is a diaphragm that functions as a self-sealing valve. For embodiments designed for small catheter access such as 4 to 9 Fr, this may be a polymer that elastically seals around the puncture once the catheter is removed. Especially for larger access catheters, such as 10 French to 24 French, a preformed aperture or slit may be cut into the material, allowing controlled and atraumatic penetration of the device and artery. The sealing element may also be fixed to the outside wall of the vessel with holdfasts through a method that facilitates percutaneous delivery through the use of a guiding wire. A method and apparatus is also described that minimizes the potential migration of emboli generated upstream from the access site, an anchoring cannula and method for facilitating localizing of the access device.
    • 描述了一种促进闭合装置的适当放置的方法和装置,并且允许容易地重复进入而不出血。 通过小的切割切口将合适的生物相容性聚合物隔膜(例如硅树脂或乳头)置于容器的外膜上。 穿刺表面是用作自密封阀的隔膜。 对于设计用于小导管接近(例如4至9Fr)的实施例,这可以是一旦导管被移除就弹性密封穿刺的聚合物。 特别是对于较大的接入导管,例如法国法国法国人(French French French French French French French French French French French French French French French French French French French French French French French French French French French) 密封元件还可以通过通过使用引导线有助于经皮输送的方法以固定方式固定在容器的外壁上。 还描述了一种方法和装置,其最小化从进入位置上游产生的栓塞的潜在迁移,锚定插管和用于便于定位接入装置的方法。