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1. 发明申请

US20100137388A1 Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof 审中-公开
标题翻译：治疗性抗生素及其使用方法
公开(公告)号：US20100137388A1
公开(公告)日：2010-06-03
申请号：US12595841
申请日：2008-04-16
申请人： Christopher J. Barden , Annette L. Henneberry , David M. Byers , Christopher R. McMaster , Donald Weaver , Fan Wu
发明人： Christopher J. Barden , Annette L. Henneberry , David M. Byers , Christopher R. McMaster , Donald Weaver , Fan Wu
IPC分类号： A61K31/41 , C07D257/04 , A61P31/12 , A61P31/04
CPC分类号： C07D417/14 , C07D409/04
摘要： The present invention provides for therapies characterized in part by co-administration or combination of antibiotic agents with medicinal compositions comprising as the pro-antibiotic active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof; [wherein X represents oxygen, sulfur, NH, or N-alkyl; R1 and R2 represent hydrogen, tetrazole, or alkyltetrazole, respectively (with the restriction that if R1 is not hydrogen, R2 must be, and vice versa); R3 represents e.g., benzyl, phenyl optionally substituted, biphenyl, napthyl, N-phenylcarboxamido, etc., R4 represents e.g. carboxylic acid, or its alkyl esters, or a bioisoteric equivalent thereof, etc.; R5 represents e.g. hydrogen, carboxylic acid, etc.] in particular, medicine which is useful as therapeutic and/or protective drugs for infectious and/or inflammatory diseases. Other relevant compounds are also provided.
摘要翻译：本发明提供了一种治疗方法，其特征在于部分通过共同施用或组合抗生素与药物组合物组合，所述药物组合物包含作为前抗生素活性成分的由式[I]表示的化合物或其药学上可接受的复合物; [其中X表示氧，硫，NH或N-烷基; R1和R2分别表示氢，四唑或烷基四唑（限制如果R1不是氢，R2必须是，反之亦然）; R 3代表例如苄基，任选取代的苯基，联苯基，萘基，N-苯基甲酰胺基等。羧酸或其烷基酯，或其生物异构体等同物等; R5代表例如氢，羧酸等]，特别是可用作感染性和/或炎性疾病的治疗和/或保护性药物的药物。还提供了其它相关化合物。

2. 发明授权

US07137499B2 Steering column mounted power transmission shifter 有权
标题翻译：转向柱安装式变速器
公开(公告)号：US07137499B2
公开(公告)日：2006-11-21
申请号：US10887410
申请日：2004-07-08
申请人： Richard K. Riefe , Tamara J. Reppuhn , Michael C. Vermeersch , David M. Byers , Ravindra Jwalapathy
发明人： Richard K. Riefe , Tamara J. Reppuhn , Michael C. Vermeersch , David M. Byers , Ravindra Jwalapathy
IPC分类号： B60W10/10 , F16H59/04
CPC分类号： F16H61/32 , F16H59/12 , F16H2061/2884 , F16H2061/326 , Y10T74/19251 , Y10T74/2003
摘要： The invention provides an apparatus for shifting an automatic transmission having a shift position select lever. The invention selectively shifts the transmission to one of a plurality of different transmission shift positions. The invention includes a steering column positionable in a passenger compartment of a vehicle. A switch is mountable in the passenger compartment of the vehicle and operable to emit a first signal representative of a desired change with respect to a transmission shift position. A motor generates a moving force and a linkage associated with the motor to transmit the moving force from the motor to a shift lever of a transmission of the vehicle. A sensor is responsive to a current transmission shift position and emits a second signal corresponding to the sensed current transmission shift position. A controller is responsive to the switch and to the sensor. The controller selectively controls the motor to engage in response to the first and second signals received from the switch and the sensor, respectively. The motor is mounted on the steering column of the vehicle.
摘要翻译：本发明提供了一种用于移动具有换档位置选择杆的自动变速器的装置。本发明有选择地将变速器转移到多个不同变速档位之一。本发明包括可定位在车辆的乘客舱中的转向柱。开关可安装在车辆的乘客舱中，并且可操作地发射代表相对于变速器档位的期望变化的第一信号。电动机产生移动力和与电动机相关联的联动装置，以将来自电动机的移动力传递到车辆变速器的变速杆。传感器响应于当前变速器换档位置，并发出对应于感测到的当前变速器档位的第二信号。控制器响应于开关和传感器。控制器选择性地控制电动机以分别响应于从开关和传感器接收到的第一和第二信号。电机安装在车辆的转向柱上。

3. 发明授权

US5790780A Analysis of failures in a computing environment 失效
标题翻译：分析计算环境中的故障
公开(公告)号：US5790780A
公开(公告)日：1998-08-04
申请号：US682974
申请日：1996-07-16
申请人： Harriet E. Brichta , Connie K. Stanley , Geoffrey J. Gerling , Henry E. Schurig, III , David M. Byers , Mitchell G. Wells
发明人： Harriet E. Brichta , Connie K. Stanley , Geoffrey J. Gerling , Henry E. Schurig, III , David M. Byers , Mitchell G. Wells
IPC分类号： G01F11/00
CPC分类号： G06F11/2205
摘要： A system (10) is provided for analyzing failures arising in computing environments. The system (10) includes an interface (12) which receives information relating to a current failure in a computing environment. A database (18) stores information relating to at least one prior failure in the same computing environment or another computing environment. A processor (22), which is coupled to the interface (12) and the database (18), compares the received information relating to the current failure with the stored information relating to the prior failure in order to find similarities. The processor (22) may then instruct a user to take appropriate action in response to similarities between the current failure and the prior failure, thereby analyzing the failures.
摘要翻译：提供了一种用于分析计算环境中出现的故障的系统（10）。系统（10）包括在计算环境中接收与当前故障有关的信息的接口（12）。数据库（18）在相同的计算环境或其他计算环境中存储与至少一个先前故障有关的信息。耦合到接口（12）和数据库（18）的处理器（22）将接收到的与当前故障相关的信息与存储的与先前故障相关的信息进行比较，以便找到相似之处。然后，处理器（22）可以指示用户响应于当前故障和先前故障之间的相似性采取适当的动作，从而分析故障。

4. 发明授权

US07178834B2 Adaptive release capsule for steering column 有权
标题翻译：转向柱自适应释放胶囊
公开(公告)号：US07178834B2
公开(公告)日：2007-02-20
申请号：US10840692
申请日：2004-05-06
申请人： Xiaoyu Li , John F. Schulz , Tracy L. Zehnder , Richard K. Riefe , David M. Byers
发明人： Xiaoyu Li , John F. Schulz , Tracy L. Zehnder , Richard K. Riefe , David M. Byers
IPC分类号： B62D1/00
CPC分类号： B62D1/195
摘要： The present invention provides an apparatus for supporting a steering wheel in a vehicle during normal vehicle handling and is breakable in response to an impact situation. The apparatus includes a member attachable to a vehicle and a steering column connected to the member for sliding movement. The apparatus also includes a capsule for connecting the member and the steering column to one another to prevent the sliding movement during normal vehicle handling. The capsule maintains the member and the steering column relative to one another, overcoming forces urging movement between the member and the steering column relative to one another, up to a first predetermined level of force. When the forces reach the first predetermined level, such as in an impact situation, the capsule breaks and releases the member and the steering column relative to one another. The apparatus of the present invention also includes an adjusting device associated with the capsule for adjusting the capsule to break in response to a second predetermined level of force lower than the first predetermined level of force.
摘要翻译：本发明提供了一种用于在正常车辆处理期间在车辆中支撑方向盘的装置，并且响应于冲击情况是可破坏的。该装置包括可附接到车辆的构件和连接到构件以用于滑动运动的转向柱。该装置还包括用于将构件和转向柱彼此连接以防止在正常车辆处理期间的滑动运动的胶囊。胶囊相对于彼此保持构件和转向柱，克服力促使构件和转向柱之间相对于彼此移动，直到第一预定水平的力。当力达到第一预定水平时，例如在冲击情况下，胶囊相对于彼此破裂并释放构件和转向柱。本发明的装置还包括与胶囊相关联的调节装置，用于响应于低于第一预定水平的力的第二预定水平力来调节胶囊而破裂。

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