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1. 发明授权

US07202028B2 Methods for the electrochemical detection of multiple target compounds 有权
标题翻译：多种靶化合物的电化学检测方法
公开(公告)号：US07202028B2
公开(公告)日：2007-04-10
申请号：US10237842
申请日：2002-09-09
申请人： H. Holden Thorp , Ivana V. Yang , David H. Stewart , John W. Groelke , Veronika A. Szalai
发明人： H. Holden Thorp , Ivana V. Yang , David H. Stewart , John W. Groelke , Veronika A. Szalai
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/005 , C12Q1/004 , C12Q1/6825 , C12Q2565/101 , C12Q2563/113
摘要： A method of detecting two different target molecules through a single electrode is carried out by (a) providing a conductive oxidation-reduction reaction detection electrode; (b) contacting a sample suspected of containing a first and second target molecule to the electrode under conditions in which the first and second target molecules are deposited on the electrode, wherein the first target molecule comprises a first label and the second target molecule comprises a second label; (c) contacting to the electrode a first transition metal complex that oxidizes the first preselected label in a first oxidation-reduction reaction and a second transition metal complex that oxidizes the first and second labels in a second oxidation-reduction reaction, with the first and second oxidation-reduction reactions producing different detectable signals; (d) detecting the presence of the first target molecule by detecting the first oxidation-reduction reaction; and (e) detecting the presence of the second target molecule by detecting the second oxidation-reduction reaction. Devices for carrying out the method are also described.
摘要翻译：通过（a）提供导电氧化还原反应检测电极来进行通过单个电极检测两种不同靶分子的方法; （b）将第一和第二靶分子沉积在电极上的条件下将疑似含有第一和第二靶分子的样品与电极接触，其中第一靶分子包含第一标记，第二靶分子包含第二个标签（c）在第一氧化还原反应中使第一预选标记物氧化的第一过渡金属络合物和在第二氧化还原反应中氧化第一和第二标记的第二过渡金属络合物与第一过渡金属络合物接触，第一和第产生不同可检测信号的第二氧化还原反应; （d）通过检测第一氧化还原反应来检测第一靶分子的存在; 和（e）通过检测第二氧化还原反应来检测第二靶分子的存在。还描述了用于执行该方法的装置。

2. 发明授权

US07081219B2 Method and machine for manufacturing molded structures using zoned pressure molding 失效
公开(公告)号：US07081219B2
公开(公告)日：2006-07-25
申请号：US10388411
申请日：2003-03-17
申请人： David H. Stewart
发明人： David H. Stewart
IPC分类号： B29C43/10 , B29C43/58 , B29C70/48
CPC分类号： B29C70/546 , B29C33/20 , B29C43/10 , B29C43/18 , B29C43/183 , B29C43/203 , B29C43/34 , B29C43/36 , B29C43/361 , B29C70/467 , B29C70/48 , B29C2043/3444 , B29C2043/3488 , B29C2043/3615 , B29C2043/525 , B29C2043/5808 , B29L2031/3041
摘要： A method for manufacturing a molded structure in a press that includes a first mold and a second mold is provided. The second mold has a plurality of pressure actuators, with each pressure actuator capable of independent operation. The method includes the steps of positioning a preform having a thickness in the first mold, placing a quantity of resin adjacent the preform so as to create a resin reservoir, and then selectively actuating one or more of the pressure actuators apply pressure to the resin reservoir to force at least a portion of the resin reservoir to infuse through the thickness of the preform. The method may also include curing the resin-infused preform, and then removing the cured resin-infused preform from the first mold.

3. 发明授权

US5551082A Protective athletic pants having diagonal protect pads around hip, buttocks and thigh areas 失效
标题翻译：保护性运动裤在臀部，臀部和大腿区域附近具有对角保护垫
公开(公告)号：US5551082A
公开(公告)日：1996-09-03
申请号：US394042
申请日：1995-02-24
申请人： David H. Stewart , Sheila C. Lehner
发明人： David H. Stewart , Sheila C. Lehner
IPC分类号： A41D1/08 , A41D13/015 , A41D13/05 , A41D13/00
CPC分类号： A41D13/0156 , A41D1/08 , A41D13/0506 , A41D13/0537 , A41D13/0581 , A41D13/0556 , A41D13/0587
摘要： An athletic garment designed to protect the wearer from injury during athletic activity such as in-line roller skating, skiing, volleyball, mountain biking, basketball, hockey, field hockey, ice skating or gymnastics. The invention uses strategically placed and rib-shaped gel, air or elastic foam padding to protect the wearer from the impact and abrasion of a fall caused by such activity.
摘要翻译：一种运动服，旨在保护穿戴者免受运动活动中的伤害，如在线滑冰，滑雪，排球，山地自行车，篮球，曲棍球，曲棍球，溜冰或体操。本发明使用策略性放置和肋状凝胶，空气或弹性泡沫填料，以保护穿戴者免受由此类活动引起的坠落的冲击和磨损。

4. 发明授权

US06558590B1 Method and machine for manufacturing molded structures using zoned pressure molding 失效
标题翻译：使用分区压力成型制造模制结构的方法和机器
公开(公告)号：US06558590B1
公开(公告)日：2003-05-06
申请号：US09936874
申请日：2001-12-28
申请人： David H. Stewart
发明人： David H. Stewart
IPC分类号： B29C4320
CPC分类号： B29C70/467 , B29C33/20 , B29C43/10 , B29C43/18 , B29C43/183 , B29C43/203 , B29C43/34 , B29C43/36 , B29C43/361 , B29C70/48 , B29C70/546 , B29C2043/3444 , B29C2043/3488 , B29C2043/3615 , B29C2043/525 , B29C2043/5808 , B29K2105/06 , B29K2105/0809 , B29L2031/3041
摘要： A method for manufacturing a molded structure in a press that includes the steps of positioning a preform (24) having a thickness in the lower mold (20), placing a quantity of resin adjacent the preform (24) so as to create a resin reservoir, and then selectively actuating one or more of the pressure actuators (28) to apply pressure to the resin reservoir to force at least a portion of the resin reservoir to infuse through the thickness of the preform (24). After the step of positioning, a top cover (32) may be placed upon the preform (24). The step of selectively actuating one or more of the pressure actuators (28) attached to an upper platen (60), may include a computer for controlling the pressure actuators (28).
摘要翻译：一种在压制机中制造模制结构的方法，包括以下步骤：将具有厚度的预成型件（24）定位在下模具（20）中，将一定数量的树脂放置在预型件（24）附近以便形成树脂储存器，然后选择性地致动一个或多个压力致动器（28）以向树脂储存器施加压力，以迫使树脂储存器的至少一部分通过预成型件（24）的厚度注入。在定位步骤之后，可以将顶盖（32）放置在预成型件（24）上。选择性地致动附接到上压板（60）的一个或多个压力致动器（28）的步骤可以包括用于控制压力致动器（28）的计算机。

5. 发明授权

US06346387B1 Detection of binding reactions using labels detected by mediated catalytic electrochemistry 有权
标题翻译：使用通过介导的催化电化学检测的标记检测结合反应
公开(公告)号：US06346387B1
公开(公告)日：2002-02-12
申请号：US09722065
申请日：2000-11-24
申请人： David H. Stewart , John W. Groelke , H. Holden Thorp , Allen E. Eckhardt
发明人： David H. Stewart , John W. Groelke , H. Holden Thorp , Allen E. Eckhardt
IPC分类号： C12Q168
CPC分类号： B82Y30/00 , B82Y5/00 , C12Q1/6825 , G01N33/5438 , C12Q2565/607 , C12Q2563/137 , C12Q2563/113
摘要： A method of detecting binding interactions and target molecules, such as proteins, protein fragments, recombinant proteins, recombinant protein fragments, extracellular matrix proteins, ligands, carbohydrates, steroids, hormones, drugs, drug candidates, immunoglobulins and receptors of eukaryotic, prokaryotic or viral origin, by mediated electrochemistry using labels that react with transition metal mediator complexes in a detectable catalytic redox reaction. These labels are attached directly to binders, target molecules, surrogate target molecules, or to affinity ligands capable of binding to the target or to surrogate target molecules capable of competing with the target for binding to another binder. The labels can be naturally present (endogenous) in the binder, target or affinity ligand, or constructed by the covalent attachment of the label to the binder, target, affinity ligand or surrogate target (exogenous).
摘要翻译：检测结合相互作用和靶分子的方法，例如蛋白质，蛋白质片段，重组蛋白，重组蛋白片段，细胞外基质蛋白，配体，碳水化合物，类固醇，激素，药物，候选药物，免疫球蛋白和真核，原核或病毒的受体通过介导的电化学使用在可检测的催化氧化还原反应中与过渡金属介体络合物反应的标记。这些标记物直接连接到粘合剂，靶分子，替代靶分子，或与能够结合靶的亲和配体或替代能与靶标竞争结合另一种粘合剂的靶分子。标签可以在粘合剂，靶或亲和配体中天然存在（内源的），或者通过标记共价连接到粘合剂，靶，亲和配体或替代靶（外源的）上构建。

6. 外观设计

USD348973S Athletic pants 失效
公开(公告)号：USD348973S
公开(公告)日：1994-07-26
申请号：US002807
申请日：1992-12-21
申请人： David H. Stewart , Sheila C. Lehner
设计人： David H. Stewart , Sheila C. Lehner

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