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1. 发明授权

US06942636B2 Method for compensating for pressure differences across valves in cassette type IV pump 有权
公开(公告)号：US06942636B2
公开(公告)日：2005-09-13
申请号：US10282967
申请日：2002-10-29
申请人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
发明人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
IPC分类号： F04B49/08 , A61M5/00 , A61M5/142 , A61M5/168 , A61M5/172 , F04B13/00 , F04B49/00 , F04B49/06 , G01P21/00 , G05D16/20 , A61N1/30
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16827 , A61M5/365 , A61M2205/12 , A61M2205/3355 , A61M2205/50 , G05D16/2046
摘要： A pump used to infuse a fluid into a patient is controlled in accordance with an algorithm that enables a microprocessor to monitor and adjust each pump cycle to compensate for a differential pressure between the pump's inlet and outlet. The algorithm defines a fluid delivery protocol that is applied in controlling the operation of the pump to achieve a desired rate, volume, and timing of the fluid infusion. Fluid is delivered by the pump when a plunger compresses an elastomeric membrane overlying a fluid chamber. Due to the small volume of the chamber, an incremental change in the plunger position before the delivery stroke produces a significant change in the delivery pressure. At the beginning of a pump cycle, the microprocessor determines the differential pressure between the inlet and outlet of the pump, and adjusts the plunger position before the delivery stroke to compensate for the differential pressure. A retraction of the plunger from the home position decreases the delivery pressure of the fluid, and an advancement of the plunger increases it. After the position of the plunger is adjusted to compensate for the differential pressure, the pump cycle proceeds. Following the plunger stroke, the outlet pressure is used to determine the actual volume of fluid delivered. The duration of the plunger stroke in the next pump cycle is adjusted to compensate for any volume delivery error produced by the differential pressure compensation.

2. 发明授权

US06497680B1 Method for compensating for pressure differences across valves in cassette type IV pump 有权
标题翻译：补充IV型泵的阀门压力差的方法
公开(公告)号：US06497680B1
公开(公告)日：2002-12-24
申请号：US09464812
申请日：1999-12-17
申请人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
发明人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
IPC分类号： A61M100
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16827 , A61M5/365 , A61M2205/12 , A61M2205/3355 , A61M2205/50 , G05D16/2046
摘要： A pump used to infuse a fluid into a patient is controlled in accordance with an algorithm that enables a microprocessor to monitor and adjust each pump cycle to compensate for a differential pressure between the pump's inlet and outlet. The algorithm defines a fluid delivery protocol that is applied in controlling the operation of the pump to achieve a desired rate, volume, and timing of the fluid infusion. Fluid is delivered by the pump when a plunger compresses an elastomeric membrane overlying a fluid chamber. Due to the small volume of the chamber, an incremental change in the plunger position before the delivery stroke produces a significant change in the delivery pressure. At the beginning of a pump cycle, the microprocessor determines the differential pressure between the inlet and outlet of the pump, and adjusts the plunger position before the delivery stroke to compensate for the differential pressure. A retraction of the plunger from the home position decreases the delivery pressure of the fluid, and an advancement of the plunger increases it. After the position of the plunger is adjusted to compensate for the differential pressure, the pump cycle proceeds. Following the plunger stroke, the outlet pressure is used to determine the actual volume of fluid delivered. The duration of the plunger stroke in the next pump cycle is adjusted to compensate for any volume delivery error produced by the differential pressure compensation.
摘要翻译：用于将流体注入患者体内的泵根据能够使微处理器监测和调节每个泵循环以补偿泵的入口和出口之间的压差的算法来控制。该算法定义了流体输送协议，其被应用于控制泵的操作以实现流体输注的期望速率，体积和时间。当柱塞压缩覆盖流体室的弹性体膜时，流体由泵输送。由于室的体积小，在输送冲程之前的柱塞位置的增量变化产生输送压力的显着变化。在泵循环开始时，微处理器确定泵的入口和出口之间的压差，并在输送冲程之前调节柱塞位置，以补偿差压。柱塞从原始位置的缩回减小了流体的输送压力，并且柱塞的前进增加了其。在调节柱塞的位置以补偿差压之后，泵循环进行。在柱塞行程之后，出口压力用于确定输送的流体的实际体积。在下一个泵循环中的柱塞行程的持续时间被调整以补偿由差压补偿产生的任何体积传递误差。

3. 发明授权

US07402154B2 Method for compensating for pressure differences across valves in cassette type IV pump 有权
标题翻译：补充IV型泵的阀门压力差的方法
公开(公告)号：US07402154B2
公开(公告)日：2008-07-22
申请号：US11157758
申请日：2005-06-21
申请人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
发明人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
IPC分类号： A61M1/00
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16827 , A61M5/365 , A61M2205/12 , A61M2205/3355 , A61M2205/50 , G05D16/2046
摘要： A pump used to infuse a fluid into a patient is controlled in accordance with an algorithm that enables a microprocessor to monitor and adjust each pump cycle to compensate for a differential pressure between the pump's inlet and outlet. The algorithm defines a fluid delivery protocol that is applied in controlling the operation of the pump to achieve a desired rate, volume, and timing of the fluid infusion. Fluid is delivered by the pump when a plunger compresses an elastomeric membrane overlying a fluid chamber. Due to the small volume of the chamber, an incremental change in the plunger position before the delivery stroke produces a significant change in the delivery pressure. At the beginning of a pump cycle, the microprocessor determines the differential pressure between the inlet and outlet of the pump, and adjusts the plunger position before the delivery stroke to compensate for the differential pressure. A retraction of the plunger from the home position decreases the delivery pressure of the fluid, and an advancement of the plunger increases it. After the position of the plunger is adjusted to compensate for the differential pressure, the pump cycle proceeds. Following the plunger stroke, the outlet pressure is used to determine the actual volume of fluid delivered. The duration of the plunger stroke in the next pump cycle is adjusted to compensate for any volume delivery error produced by the differential pressure compensation.
摘要翻译：用于将流体注入患者体内的泵根据能够使微处理器监测和调节每个泵循环以补偿泵的入口和出口之间的压差的算法来控制。该算法定义了流体输送协议，其被应用于控制泵的操作以实现流体输注的期望速率，体积和时间。当柱塞压缩覆盖流体室的弹性体膜时，流体由泵输送。由于室的体积小，在输送冲程之前的柱塞位置的增量变化产生输送压力的显着变化。在泵循环开始时，微处理器确定泵的入口和出口之间的压差，并在输送冲程之前调节柱塞位置，以补偿差压。柱塞从原始位置的缩回减小了流体的输送压力，并且柱塞的前进增加了其。在调节柱塞的位置以补偿差压之后，泵循环进行。在柱塞行程之后，出口压力用于确定输送的流体的实际体积。在下一个泵循环中的柱塞行程的持续时间被调整以补偿由差压补偿产生的任何体积传递误差。

4. 发明授权

US07407489B2 Methods for compensating for pressure differences across valves in IV pumps 有权
标题翻译：补偿IV泵阀门压力差的方法
公开(公告)号：US07407489B2
公开(公告)日：2008-08-05
申请号：US11157755
申请日：2005-06-21
申请人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
发明人： Peter A. Holst , David A. Krajewski , Rudolph J. Maske
IPC分类号： A61N1/30
CPC分类号： A61M5/14224 , A61M5/16809 , A61M5/16827 , A61M5/365 , A61M2205/12 , A61M2205/3355 , A61M2205/50 , G05D16/2046
摘要： A pump used to infuse a fluid into a patient is controlled in accordance with an algorithm that enables a microprocessor to monitor and adjust each pump cycle to compensate for a differential pressure between the pump's inlet and outlet. The algorithm defines a fluid delivery protocol that is applied in controlling the operation of the pump to achieve a desired rate, volume, and timing of the fluid infusion. Fluid is delivered by the pump when a plunger compresses an elastomeric membrane overlying a fluid chamber. Due to the small volume of the chamber, an incremental change in the plunger position before the delivery stroke produces a significant change in the delivery pressure. At the beginning of a pump cycle, the microprocessor determines the differential pressure between the inlet and outlet of the pump, and adjusts the plunger position before the delivery stroke to compensate for the differential pressure. A retraction of the plunger from the home position decreases the delivery pressure of the fluid, and an advancement of the plunger increases it. After the position of the plunger is adjusted to compensate for the differential pressure, the pump cycle proceeds. Following the plunger stroke, the outlet pressure is used to determine the actual volume of fluid delivered. The duration of the plunger stroke in the next pump cycle is adjusted to compensate for any volume delivery error produced by the differential pressure compensation.
摘要翻译：用于将流体注入患者体内的泵根据能够使微处理器监测和调节每个泵循环以补偿泵的入口和出口之间的压差的算法来控制。该算法定义了流体输送协议，其被应用于控制泵的操作以实现流体输注的期望速率，体积和时间。当柱塞压缩覆盖流体室的弹性体膜时，流体由泵输送。由于室的体积小，在输送冲程之前的柱塞位置的增量变化产生输送压力的显着变化。在泵循环开始时，微处理器确定泵的入口和出口之间的压差，并在输送冲程之前调节柱塞位置，以补偿差压。柱塞从原始位置的缩回减小了流体的输送压力，并且柱塞的前进增加了其。在调节柱塞的位置以补偿差压之后，泵循环进行。在柱塞行程之后，出口压力用于确定输送的流体的实际体积。在下一个泵循环中的柱塞行程的持续时间被调整以补偿由差压补偿产生的任何体积传递误差。

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