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1. 发明授权

US09574978B2 Sampler 有权
标题翻译：取样器
公开(公告)号：US09574978B2
公开(公告)日：2017-02-21
申请号：US13990965
申请日：2011-12-01
申请人： Dae-Sung Hur , Ji-Young Park
发明人： Dae-Sung Hur , Ji-Young Park
IPC分类号： G01N1/38 , B01L3/02 , B01L3/00 , A61B5/145
CPC分类号： G01N1/38 , A61B5/14 , B01L3/0248 , B01L3/502 , B01L3/563 , B01L2200/0605 , B01L2300/046 , B01L2300/047 , B01L2300/0672 , B01L2300/0832 , B01L2300/0838 , B01L2400/0406 , B01L2400/0683
摘要： Disclosed therein is a sampler. The sampler includes: a chamber accommodating a fluid or solid reagent therein and being sealed at both ends with penetrable films; a tube joined with the chamber at one side, the tube having a hollow portion therein; and a movable bar having a tip which is formed at one end and has a specimen extracting portion, the tip being guided and moved through a hollow portion, the tip being adapted for mixing the specimen extracted by the specimen extracting portion with the reagent so as to form a diluted solution while penetrating through one end of the chamber and adapted for quantitatively discharging out the diluted solution while penetrating through the other end of the chamber.
摘要翻译：其中公开了采样器。采样器包括：容纳流体或固体试剂的室，并在两端用可渗透膜密封; 在一侧与腔室连接的管，其中具有中空部分的管; 以及可动杆，其具有在一端形成并具有样本提取部的尖端，所述尖端被引导并移动通过中空部，所述尖端适于将由所述检体提取部提取的样本与所述试剂混合，以在穿透室的一端时形成稀释溶液，并适于在渗透室的另一端时定量地排出稀释溶液。

2. 发明申请

US20100112631A1 Chip Having Microchannel For Counting Specific Micro Particles Among Floating Micro Particle Mixture By Optical Means And A Method For Counting Micro Particles Using The Same 审中-公开
标题翻译：具有用于通过光学装置计数浮动微粒子混合物中的特定微粒子的微通道的芯片和用于计数使用其的微粒子的方法
公开(公告)号：US20100112631A1
公开(公告)日：2010-05-06
申请号：US12522377
申请日：2008-01-07
申请人： Dae Sung Hur , Chanil Chung , Seung Hwa Jeon , Jun Keun Chang
发明人： Dae Sung Hur , Chanil Chung , Seung Hwa Jeon , Jun Keun Chang
IPC分类号： C12Q1/06
CPC分类号： A61B5/0059 , A61B5/14546
摘要： A microchannel chip for counting floating microparticles with an optical method is provided. The depth of the microchannel chip is made to be a depth of field such that a clear and sharp optical image of microparticles can be obtained, without necessarily diluting the microparticle mixture inside the microchannel. Consequently, a microparticle counting instrument can easily count microparticles shown on an optical image of the microchannel. Particularly, it enables to count more easily the number of CD3 cells CD4 cells or CD8 cells in white blood cells being stained, without lysing or diluting red blood cells. Therefore, the microchannel chip can advantageously used for counting the number of CD3 cells, CD4 cells or CD8 cells in blood of an AIDS patient to monitor the progression of AIDS.
摘要翻译：提供了一种用于用光学方法计数浮动微粒的微通道芯片。使微通道芯片的深度成为景深，使得可以获得微粒的清晰和清晰的光学图像，而不必将微通道内的微粒混合物稀释。因此，微粒计数装置可以容易地计数微通道的光学图像上所示的微粒。特别地，它能够更容易地计数正在染色的白细胞中CD3细胞CD4细胞或CD8细胞的数量，而不会溶解或稀释红细胞。因此，微通道芯片可以有利地用于计数艾滋病患者血液中的CD3细胞，CD4细胞或CD8细胞的数量，以监测AIDS的发展。

3. 发明申请

US20100012575A1 Channel Filter Having Surface Topology For Filtering Micro Particles And Method For Manufacturing Same 有权
标题翻译：具有用于过滤微粒子的表面拓扑的通道滤波器及其制造方法相同
公开(公告)号：US20100012575A1
公开(公告)日：2010-01-21
申请号：US12513189
申请日：2007-11-02
申请人： Dae-Sung Hur , Jun-Ha Park , Chan- Il Chung , Jun-Keun Chang
发明人： Dae-Sung Hur , Jun-Ha Park , Chan- Il Chung , Jun-Keun Chang
IPC分类号： B01D35/28 , B29C33/42 , B44C1/22 , B01D35/00
CPC分类号： B01D67/0062 , B01D35/28 , B01L3/502753 , G01N30/90
摘要： Disclosed is a channel filter for separating microparticles, and more particularly to a channel filter which can easily separate a sample having various sized microparticles by using a surface topology. In the disclosed channel filter, a topology having an upward/downward reference height from a sample inlet to an outlet is continuously or discontinuously formed, and thus it is possible to efficiently separate microparticles from a sample liquid.
摘要翻译：公开了一种用于分离微粒的通道过滤器，更具体地说，涉及通过使用表面拓扑结构容易地分离具有各种尺寸的微粒的样品的通道过滤器。在所公开的通道过滤器中，连续地或不连续地形成具有从样品入口到出口的向上/向下参考高度的拓扑，因此可以有效地从样品液体中分离微粒。

4. 发明申请

US20140248197A1 SAMPLER 有权
标题翻译：取样器
公开(公告)号：US20140248197A1
公开(公告)日：2014-09-04
申请号：US14349368
申请日：2012-05-15
申请人： Dae Sung Hur
发明人： Dae Sung Hur
IPC分类号： G01N1/34
CPC分类号： G01N1/34 , A61B5/1405 , A61B5/150022 , A61B5/150343 , A61B5/150755 , B01L3/502753 , B01L2300/0681 , B01L2300/0809 , B01L2300/0832 , B01L2400/0406 , B01L2400/0478 , G01N33/491
摘要： The present invention relates to a sampler which is capable of rapidly and easily separating blood corpuscles from blood, being operated conveniently, and directly using extracted plasma. According to one embodiment of the present invention, a sampler includes a chamber and a membrane guide. Here, the chamber includes an insertion unit having an insertion hole on one side, wherein the other side is opened, and an inner side includes a receiving space for receiving a sample. Additionally, one side of the membrane guide is combined to the membrane, and the membrane guide includes a channel wherein filtered materials, which are filtered through the membrane among the samples received in the receiving space, are moved in a gravitational direction.
摘要翻译：本发明涉及一种能够快速，容易地将血液从血液中分离并且操作方便，并直接使用提取的等离子体的取样器。根据本发明的一个实施例，采样器包括腔室和膜引导件。这里，腔室包括在一侧具有插入孔的插入单元，其中另一侧被打开，并且内侧包括用于接收样品的容纳空间。此外，膜引导件的一侧与膜组合，并且膜引导件包括通道，其中在接收空间中接收的样品中通过膜过滤的过滤材料在重力方向上移动。

5. 发明申请

US20130243665A1 SAMPLER 有权
标题翻译：取样器
公开(公告)号：US20130243665A1
公开(公告)日：2013-09-19
申请号：US13990965
申请日：2011-12-01
申请人： Dae-Sung Hur , Ji-Young Park
发明人： Dae-Sung Hur , Ji-Young Park
IPC分类号： G01N1/38
CPC分类号： G01N1/38 , A61B5/14 , B01L3/0248 , B01L3/502 , B01L3/563 , B01L2200/0605 , B01L2300/046 , B01L2300/047 , B01L2300/0672 , B01L2300/0832 , B01L2300/0838 , B01L2400/0406 , B01L2400/0683
摘要： Disclosed therein is a sampler. The sampler includes: a chamber accommodating a fluid or solid reagent therein and being sealed at both ends with penetrable films; a tube joined with the chamber at one side, the tube having a hollow portion therein; and a movable bar having a tip which is formed at one end and has a specimen extracting portion, the tip being guided and moved through a hollow portion, the tip being adapted for mixing the specimen extracted by the specimen extracting portion with the reagent so as to form a diluted solution while penetrating through one end of the chamber and adapted for quantitatively discharging out the diluted solution while penetrating through the other end of the chamber.
摘要翻译：其中公开了采样器。采样器包括：容纳流体或固体试剂的室，并在两端用可渗透膜密封; 在一侧与腔室连接的管，其中具有中空部分的管; 以及可动杆，其具有在一端形成并具有样本提取部的尖端，所述尖端被引导并移动通过中空部，所述尖端适于将由所述检体提取部提取的样本与所述试剂混合，以在穿透室的一端时形成稀释溶液，并适于在渗透室的另一端时定量地排出稀释溶液。

6. 发明申请

US20110044862A1 METHOD FOR BONDING PLASTIC MICRO CHIP 有权
标题翻译：用于粘结塑料微芯片的方法
公开(公告)号：US20110044862A1
公开(公告)日：2011-02-24
申请号：US12916098
申请日：2010-10-29
申请人： Jun Keun CHANG , Dae Sung Hur , Chanil Chung , Jun Ha Park , Han Sang Jo
发明人： Jun Keun CHANG , Dae Sung Hur , Chanil Chung , Jun Ha Park , Han Sang Jo
IPC分类号： B01L3/00
CPC分类号： B29C65/4895 , B01L3/5027 , B01L3/502707 , B01L2200/12 , B01L2300/0816 , B01L2300/0825 , B01L2300/0887 , B29C59/14 , B29C65/02 , B29C65/08 , B29C65/14 , B29C65/16 , B29C65/48 , B29C65/54 , B29C65/548 , B29C66/02 , B29C66/028 , B29C66/1122 , B29C66/3022 , B29C66/53461 , B29C66/54 , B29C66/542 , B29C66/71 , B29C66/73161 , B29C66/8322 , B29K2023/06 , B29K2023/12 , B29K2025/00 , B29K2033/12 , B29K2069/00 , B29K2101/12 , B29K2995/0026 , B29L2031/756 , H01L25/046 , H01L2924/0002 , Y10T156/1064 , B29C59/16 , B29C65/00 , H01L2924/00 , B29K2067/003 , B29K2025/06
摘要： Disclosed is a method of bonding upper and lower substrates for manufacturing a plastic micro chip comprising the upper substrate, the lower substrate and a sample filling space having a predetermined height for filling a sample between the upper and lower substrates. According to the method, the upper and lower substrates are bonded by introducing an organic solvent between the upper and lower substrates. In addition, the invention provides a method of manufacturing a micro chip using the method and a micro chip manufactured according to the method. According to the invention, it is possible to easily and precisely bond the upper and lower substrates of the plastic micro chip.
摘要翻译：公开了一种用于制造塑料微芯片的上基板和下基板的方法，其包括上基板，下基板和具有预定高度的样品填充空间，用于在上基板和下基板之间填充样品。根据该方法，通过在上基板和下基板之间引入有机溶剂来粘合上基板和下基板。另外，本发明提供使用该方法制造微芯片的方法和根据该方法制造的微芯片。根据本发明，可以容易且精确地粘合塑料微芯片的上下基板。

7. 发明申请

US20110036152A1 CHIP FOR ANALYZING FLUIDS 有权
标题翻译：用于分析流体的芯片
公开(公告)号：US20110036152A1
公开(公告)日：2011-02-17
申请号：US12729583
申请日：2010-03-23
申请人： Jun Ha Park , Chan Il Chung , Jun Keun Chang , Dae Sung Hur , Ji Young Park
发明人： Jun Ha Park , Chan Il Chung , Jun Keun Chang , Dae Sung Hur , Ji Young Park
IPC分类号： G01N33/48
CPC分类号： B01L3/5027 , B01L3/502723 , B01L2300/0816 , B01L2300/0851 , B01L2300/0858 , B01L2300/089 , B01L2400/0406 , B01L2400/086
摘要： Disclosed is a fluid analysis chip including a microchannel formed within the chip. The chip includes a sample and a sample outlet communicating with an outside of the chip, and has a structure where the sample inlet and the sample outlet communicate with each other through the closed channel. An expanding part formed in a longitudinal direction of a channel in such a manner that a pair of inner walls corresponding to each other has a larger sectional area at a part or a whole thereof is formed. Therefore, fluids, which pass through the channel adjacent to the expanding part, move while making contact with only another pair of inner walls of the channel, which correspond to each other.
摘要翻译：公开了一种流体分析芯片，其包括形成在芯片内的微通道。芯片包括与芯片的外部连通的样品和样品出口，并且具有样品入口和样品出口通过封闭通道彼此连通的结构。形成在通道的纵向方向上的扩张部分，使得彼此对应的一对内壁在其一部分或全部具有较大的截面面积。因此，通过邻近膨胀部的通道的流体在仅与通道对应的另一对内壁接触的同时移动。

8. 发明申请

US20130064714A1 CHIP FOR FLUID ANALYSIS 审中-公开
标题翻译：流体分析芯片
公开(公告)号：US20130064714A1
公开(公告)日：2013-03-14
申请号：US13698697
申请日：2011-05-17
申请人： Dae Sung Hur , Ji Young Park
发明人： Dae Sung Hur , Ji Young Park
IPC分类号： G01N21/64
CPC分类号： B01L3/502715 , B01L3/502746 , B01L7/00 , B01L2200/027 , B01L2200/028 , B01L2300/0816 , B01L2300/0822 , B01L2300/0825 , B01L2300/0864 , B01L2300/1805 , B01L2400/0406
摘要： Disclosed herein is a chip for analyzing fluids which restricts the flow of a fluid and the flow velocity of the fluid at a reaction unit, where an antigen-antibody reaction occurs, to increase reactivity and sensitivity.
摘要翻译：本文公开了一种用于分析流体的芯片，其限制流体的流动和在发生抗原 - 抗体反应的反应单元处的流体的流速，以增加反应性和灵敏度。

9. 发明申请

US20110286887A1 OPEN TYPE GROOVE CHANNEL CHIP 审中-公开
标题翻译：开放式沟槽通道芯片
公开(公告)号：US20110286887A1
公开(公告)日：2011-11-24
申请号：US13147407
申请日：2010-02-08
申请人： Dae-Sung Hur
发明人： Dae-Sung Hur
IPC分类号： G01N30/00 , G01N21/00 , G01N33/48
CPC分类号： G01N33/54386 , B01L3/5027 , B01L3/502746 , B01L2300/0816 , B01L2300/0887
摘要： The present invention relates to an open-type groove channel chip. More particularly, the present invention relates to an open-type groove channel chip comprising a main body upper plate (11), a main body lower plate (12), an injection portion (14) into which an analytical sample is to be injected, a discharge portion (13) for discharging the analytical sample, a microchannel (15) in which the analytical sample is to flow, and an open portion (16) formed at the main body of the channel chip to expose one side of the microchannel (15).
摘要翻译：本发明涉及一种开放型槽沟道芯片。更具体地说，本发明涉及一种开放式沟槽芯片，其包括主体上板（11），主体下板（12），注入分析用样品的注入部（14）用于排出分析样品的放电部分（13），分析样品要流过的微通道（15）和形成在通道芯片主体处的开口部分（16），以暴露微通道的一侧（ 15）。

10. 发明申请

US20110268612A1 MICROCHANNEL INTO WHICH A POROUS POLYMER IS INSERTED 审中-公开
标题翻译：微波导管插入多孔聚合物
公开(公告)号：US20110268612A1
公开(公告)日：2011-11-03
申请号：US13142317
申请日：2009-12-21
申请人： Dae-Sung Hur
发明人： Dae-Sung Hur
IPC分类号： G01N33/00 , B01J8/02
CPC分类号： G01N30/32 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L2300/0663 , B01L2300/069 , G01N30/6082 , G01N30/74 , G01N2030/324
摘要： A microchannel is disclosed. The present invention relates to a microchannel having a porous polymer inserted therein, more particularly, to a microchannel including a channel body and a porous polymer inserted in a surface of the channel body to be employed as a valve which can locally maximize a surface area of reaction between samples and reagents and which can control flow of a fluid in the microchannel.
摘要翻译：公开了一种微通道。本发明涉及一种具有插入其中的多孔聚合物的微通道，更具体地，涉及一种微通道，其包括通道体和插入在通道体表面中的多孔聚合物，以用作阀门，其可以局部地使表面积最大化样品和试剂之间的反应，并且可以控制微通道中流体的流动。

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