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1. 发明授权

US5376795A Emission-transmission imaging system using single energy and dual energy transmission and radionuclide emission data 失效
标题翻译：使用单能量和双能量传输和放射性核素发射数据的发射透射成像系统
公开(公告)号：US5376795A
公开(公告)日：1994-12-27
申请号：US958980
申请日：1992-10-09
申请人： Bruce H. Hasegawa , Robert G. Gould , Thomas F. Lang , J. Keenan Brown , Joseph A. Heanue , Christopher E. Cann
发明人： Bruce H. Hasegawa , Robert G. Gould , Thomas F. Lang , J. Keenan Brown , Joseph A. Heanue , Christopher E. Cann
IPC分类号： G01T1/164 , G01T1/29 , H05G1/60 , G01T1/166
CPC分类号： G01T1/1615 , A61B6/037 , A61B6/5235 , G01T1/1611 , G01T1/1642 , G01T1/1647 , G01T1/1648 , G01T1/2985 , H05G1/60
摘要： Radionuclide emission imaging is improved by correcting emission-transmission data for attenuation along calculated path lengths and through calculated basis material. X-ray transmission data are used to develop an attenuation map through an object which is then used in reconstructing an image based on emission data, Radiation detection circuitry is provided which has different operating modes in detecting the x-ray and emission photons passing through the object. An iterative process is used to reconstruct the radionuclide distribution using the radionuclide projection data and the attenuation map based on physical characteristics of the object being imaged. Subsets of the complete radionuclide projection data are used to reconstruct image subsets of the radionuclide distribution. The image subsets can be generated concurrently with the acquisition of the radionuclide projection data or following acquisition of all data.
摘要翻译：通过根据计算的路径长度和通过计算的基础材料校正用于衰减的发射数据来改善放射性核素发射成像。 X射线透射数据用于通过物体开发衰减图，该物体然后用于基于发射数据重建图像。提供了辐射检测电路，其在检测通过X射线的x射线和发射光子时具有不同的操作模式目的。迭代过程用于使用放射性核素投影数据和基于被成像对象的物理特性的衰减图来重构放射性核素分布。完整的放射性核素投影数据的子集用于重建放射性核素分布的图像子集。图像子集可以与获取放射性核素投影数据同时产生，也可以在获取所有数据之后产生。

2. 发明授权

US5155365A Emission-transmission imaging system using single energy and dual energy transmission and radionuclide emission data 失效
标题翻译：使用单能量和双能量传输和放射性核素发射数据的发射透射成像系统
公开(公告)号：US5155365A
公开(公告)日：1992-10-13
申请号：US549890
申请日：1990-07-09
申请人： Christopher E. Cann , Bruce H. Hasegawa , Eric L. Gingold
发明人： Christopher E. Cann , Bruce H. Hasegawa , Eric L. Gingold
IPC分类号： G01T1/164 , H05G1/60
CPC分类号： A61B6/4241 , A61B6/037 , G01T1/1615 , G01T1/1642 , G01T1/1647 , G01T1/1648 , H05G1/60
摘要： Radionuclide emission imaging is improved by correcting emission transmission data for attenuation along calculated path lengths and through calculated basis material. Single or dual energy projector data can be simultaneously obtained with radionuclide emission data to improve localization of radionuclide uptake. Dual energy x-ray projection techniques are used to calculate the path lengths and basis material (bone, tissue, fat). The radionuclide emission data and the transmitted x-ray data are simultaneously obtained using an energy selective photon detector whereby problems of misregistration are overcome. The dual-energy x-ray projection data are utilized to determine material-specific properties and are recombined into an effectively monoenergetic image, eliminating inaccuracies in material property estimation due to beam hardening. Use of a single instrument for simultaneous data collection also reduces technician time and floor space in a hospital.
摘要翻译：通过根据计算的路径长度和通过计算的基础材料校正用于衰减的发射透射数据来改善放射性核素发射成像。可以使用放射性核素发射数据同时获得单或双能量投影仪数据，以改善放射性核素摄取的定位。双能X射线投影技术用于计算路径长度和基础材料（骨骼，组织，脂肪）。使用能量选择性光子检测器同时获得放射性核素发射数据和透射的X射线数据，从而克服了重合失调的问题。双能x射线投影数据用于确定材料特性，并重新组合成有效的单能量图像，消除了由于光束硬化引起的材料性能估计的不准确性。使用单个仪器同时进行数据采集也可减少医院的技术人员时间和占地面积。

3. 发明授权

US5172695A Method for improved prediction of bone fracture risk using bone mineral density in structural analysis 失效
$Method for improved prediction of bone fracture risk using bone mineral density in structural analysis$
标题翻译：在结构分析中使用骨矿物质密度改善骨折风险预测的方法
公开(公告)号：US5172695A
公开(公告)日：1992-12-22
申请号：US580045
申请日：1990-09-10
申请人： Christopher E. Cann , Kenneth G. Faulkner
发明人： Christopher E. Cann , Kenneth G. Faulkner
IPC分类号： A61B6/00 , G06F19/00
CPC分类号： G06F19/3437 , A61B6/505
摘要： A non-invasive in-vivo method of analyzing a bone for fracture risk includes obtaining data from the bone such as by computed tomography or projection imaging which data represents a measure of bone material characteristics such as bone mineral density. The distribution of the bone material characteristics is used to generate a finite element method (FEM) mesh from which load capability of the bone can be determined. In determining load capability, the bone is mathematically "compressed", and stress, strain force, force/area versus bone material characteristics are determined.
摘要翻译：用于骨折分析骨的非侵入性体内方法包括从骨骼获得数据，例如通过计算机断层摄影或投影成像，该数据表示诸如骨矿物质密度的骨材料特征的量度。骨材料特性的分布用于生成有限元法（FEM）网格，可以确定骨骼的负荷能力。在确定负荷能力时，骨骼在数学上“压缩”，确定了应力，应变力，力/面积与骨材料特性。

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