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1. 发明授权

US5155365A Emission-transmission imaging system using single energy and dual energy transmission and radionuclide emission data 失效
标题翻译：使用单能量和双能量传输和放射性核素发射数据的发射透射成像系统
公开(公告)号：US5155365A
公开(公告)日：1992-10-13
申请号：US549890
申请日：1990-07-09
申请人： Christopher E. Cann , Bruce H. Hasegawa , Eric L. Gingold
发明人： Christopher E. Cann , Bruce H. Hasegawa , Eric L. Gingold
IPC分类号： G01T1/164 , H05G1/60
CPC分类号： A61B6/4241 , A61B6/037 , G01T1/1615 , G01T1/1642 , G01T1/1647 , G01T1/1648 , H05G1/60
摘要： Radionuclide emission imaging is improved by correcting emission transmission data for attenuation along calculated path lengths and through calculated basis material. Single or dual energy projector data can be simultaneously obtained with radionuclide emission data to improve localization of radionuclide uptake. Dual energy x-ray projection techniques are used to calculate the path lengths and basis material (bone, tissue, fat). The radionuclide emission data and the transmitted x-ray data are simultaneously obtained using an energy selective photon detector whereby problems of misregistration are overcome. The dual-energy x-ray projection data are utilized to determine material-specific properties and are recombined into an effectively monoenergetic image, eliminating inaccuracies in material property estimation due to beam hardening. Use of a single instrument for simultaneous data collection also reduces technician time and floor space in a hospital.
摘要翻译：通过根据计算的路径长度和通过计算的基础材料校正用于衰减的发射透射数据来改善放射性核素发射成像。可以使用放射性核素发射数据同时获得单或双能量投影仪数据，以改善放射性核素摄取的定位。双能X射线投影技术用于计算路径长度和基础材料（骨骼，组织，脂肪）。使用能量选择性光子检测器同时获得放射性核素发射数据和透射的X射线数据，从而克服了重合失调的问题。双能x射线投影数据用于确定材料特性，并重新组合成有效的单能量图像，消除了由于光束硬化引起的材料性能估计的不准确性。使用单个仪器同时进行数据采集也可减少医院的技术人员时间和占地面积。

2. 发明授权

US5376795A Emission-transmission imaging system using single energy and dual energy transmission and radionuclide emission data 失效
标题翻译：使用单能量和双能量传输和放射性核素发射数据的发射透射成像系统
公开(公告)号：US5376795A
公开(公告)日：1994-12-27
申请号：US958980
申请日：1992-10-09
申请人： Bruce H. Hasegawa , Robert G. Gould , Thomas F. Lang , J. Keenan Brown , Joseph A. Heanue , Christopher E. Cann
发明人： Bruce H. Hasegawa , Robert G. Gould , Thomas F. Lang , J. Keenan Brown , Joseph A. Heanue , Christopher E. Cann
IPC分类号： G01T1/164 , G01T1/29 , H05G1/60 , G01T1/166
CPC分类号： G01T1/1615 , A61B6/037 , A61B6/5235 , G01T1/1611 , G01T1/1642 , G01T1/1647 , G01T1/1648 , G01T1/2985 , H05G1/60
摘要： Radionuclide emission imaging is improved by correcting emission-transmission data for attenuation along calculated path lengths and through calculated basis material. X-ray transmission data are used to develop an attenuation map through an object which is then used in reconstructing an image based on emission data, Radiation detection circuitry is provided which has different operating modes in detecting the x-ray and emission photons passing through the object. An iterative process is used to reconstruct the radionuclide distribution using the radionuclide projection data and the attenuation map based on physical characteristics of the object being imaged. Subsets of the complete radionuclide projection data are used to reconstruct image subsets of the radionuclide distribution. The image subsets can be generated concurrently with the acquisition of the radionuclide projection data or following acquisition of all data.
摘要翻译：通过根据计算的路径长度和通过计算的基础材料校正用于衰减的发射数据来改善放射性核素发射成像。 X射线透射数据用于通过物体开发衰减图，该物体然后用于基于发射数据重建图像。提供了辐射检测电路，其在检测通过X射线的x射线和发射光子时具有不同的操作模式目的。迭代过程用于使用放射性核素投影数据和基于被成像对象的物理特性的衰减图来重构放射性核素分布。完整的放射性核素投影数据的子集用于重建放射性核素分布的图像子集。图像子集可以与获取放射性核素投影数据同时产生，也可以在获取所有数据之后产生。

3. 发明授权

US4497062A Digitally controlled X-ray beam attenuation method and apparatus 失效
标题翻译：数字控制X射线束衰减方法和装置
公开(公告)号：US4497062A
公开(公告)日：1985-01-29
申请号：US501607
申请日：1983-06-06
申请人： Charles A. Mistretta , Walter W. Peppler , Balakrishna V. Kudva , Bruce H. Hasegawa , James T. Dobbins, III
发明人： Charles A. Mistretta , Walter W. Peppler , Balakrishna V. Kudva , Bruce H. Hasegawa , James T. Dobbins, III
IPC分类号： G21K3/00 , A61B6/00 , G21K1/10 , G21K5/02 , H05G1/26 , H05G1/60 , G03B41/16 , H05G3/00
CPC分类号： G21K1/10 , H05G1/26 , H05G1/60
摘要： X-ray compensation masks (51) are prepared by exposing an X-ray target object (43), such as a patient, to a first beam of X-rays. The X-ray fluence from the patient is received by an electronic image receptor (44) which provides an output signal indicating the intensity of the X-rays at all positions in the image field. The image information is converted by an image processor (47) to transformed X-ray intensity values for a plurality of pixels which cover the image field. A mask generating controller (48) determines the minimum transformed intensity value for any pixel, assigns to each pixel an attenuation number which is proportional to the difference between the transformed intensity value for the pixel and the minimum transformed intensity value, and issues control signals to a mask former (49) which deposits on a non-attenuating substrate (50) attenuating masses in a two dimensional array of pixels with the mass thickness in each pixel proportional to the attenuation number. When the mask (51) is inserted into the beam from the X-ray source (41), and a second exposure taken, the X-ray fluence passing through both the attenuating mask (51) and the patient (43) will be substantially equalized across the image field.
摘要翻译：通过将诸如患者的X射线目标物体（43）暴露于第一X射线束来制备X射线补偿掩模（51）。来自患者的X射线能量密度由电子图像接收器（44）接收，电子图像接收器（44）提供指示图像场中所有位置的X射线强度的输出信号。图像信息由图像处理器（47）转换为覆盖图像场的多个像素的变换的X射线强度值。掩模生成控制器（48）确定任何像素的最小变换强度值，向每个像素分配与像素的变换强度值和最小变换强度值之间的差成比例的衰减数，并将控制信号发送到沉积在非衰减衬底（50）上的掩模形成器（49），其衰减像素的二维阵列中的质量，每个像素中的质量厚度与衰减数量成正比。当掩模（51）从X射线源（41）插入光束中并进行第二次曝光时，穿过衰减掩模（51）和患者（43）的X射线能量密度将基本上在整个图像场均衡。

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