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    • 8. 发明申请
    • COMBINATION - TYPE COLLECTOR RING UNIT
    • 组合 - 类型收集器环单元
    • US20090091208A1
    • 2009-04-09
    • US11960124
    • 2007-12-19
    • Meng-Chiu YUSu-Chen Liao
    • Meng-Chiu YUSu-Chen Liao
    • H01R39/00H01R39/08
    • H01R39/08
    • A collector ring unit includes a base, and a plurality of insulated spacer rings sleeved onto the base respectively and each having a ring body, a plurality of through holes through the ring body, and a notch formed on the ring body. A plurality of conductive slip rings are respectively sleeved onto the ring bodies of the insulated spacer rings and each have a socket. A plurality of conductive trips each have one end inserted into the socket of one conductive slip ring and received in the notch of one insulated spacer ring, and the other end passing through the through holes of the other insulated spacer rings and protruded out of the outermost insulated spacer ring. By means of addition or reduction of the numbers of the spacer rings, slip rings and conductive strips, the dimension of the collector ring unit of the invention can be changed.
    • 集电环单元包括基座和分别套在基座上的多个隔离间隔环,每个具有环形体,多个通过环体的通孔和形成在环体上的凹口。 多个导电滑环分别套在绝缘间隔环的环体上,并且每个具有插座。 多个导电跳闸各自具有插入一个导电滑环的插座中的一端,并被接收在一个绝缘隔离环的凹口中,另一端穿过另一绝缘间隔环的通孔并突出到最外侧 绝缘间隔环。 通过添加或减少间隔环,滑环和导电条的数量,可以改变本发明的集电环单元的尺寸。
    • 9. 发明申请
    • Method for Preparing Lipid-Spacer-Reactive Functional Group-Peptide
    • 脂质间隔反应性功能团肽的制备方法
    • US20080139703A1
    • 2008-06-12
    • US12029324
    • 2008-02-11
    • Te-Wei LeeShu-Pei ChiuChiu-Yu YuTsui-Jung ChangChih-Hsien Chang
    • Te-Wei LeeShu-Pei ChiuChiu-Yu YuTsui-Jung ChangChih-Hsien Chang
    • C08L89/00
    • A61K9/1271A61K9/1278A61K47/62A61K47/6911C07K14/6555Y02P20/55
    • The present invention discloses a method for preparing lipid-spacer-reactive functional group-peptide, wherein the peptide consists of 3 to 16 amino acid residues in which at least one amino acid residue is lysine (Lys), the reactive functional group is a formula of —X—CO—Y—CO—, wherein X represents an oxygen atom or a nitrogen atom, and Y represents C1-6 alkylene which may be interrupted by one or two oxygen or nitrogen atom(s), the spacer is a hydrophilic polymer, and the lipid is phosphatidylethanoaminecarbonyl represented by the formula (I): R1 and R2 are the same or different and individually represent linear or branch C7-30 alkyl or linear or branch C7-30 alkenyl; which is characterized in that the reaction is carried out in a liquid phase and comprises the following steps of (a) firstly protecting Lys amino acid residue in the peptide through a protection group; (b) subsequently reacting the peptide with the lipid-spacer-reactive functional group; and (c) finally removing the protection group from Lys amino acid residue in the peptide.
    • 本发明公开了一种制备脂质 - 间隔物反应性官能团肽的方法,其中肽由3至16个氨基酸残基组成,其中至少一个氨基酸残基为赖氨酸(Lys),反应性官能团为式 的-X-CO-Y-CO-,其中X表示氧原子或氮原子,Y表示可被一个或两个氧或氮原子间隔的C 1-6亚烷基( s),间隔基是亲水性聚合物,并且脂质是由式(I)表示的磷脂酰硫代氨基羰基:R 1和R 2都相同或不同,并且各自代表 直链或支链C 7-30烷基或直链或支链C 7-30链烯基; 其特征在于反应在液相中进行,并包括以下步骤:(a)首先通过保护基保护肽中的Lys氨基酸残基; (b)随后使肽与脂质 - 间隔物反应性官能团反应; 和(c)最后从肽中的Lys氨基酸残基中除去保护基团。