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1. 发明申请

US20110054441A1 METHODS, DEVICES, AND COMPOSITIONS FOR INTRAVITREAL INJECTION 审中-公开
标题翻译：方法，装置和组合物进行静脉注射
公开(公告)号：US20110054441A1
公开(公告)日：2011-03-03
申请号：US12853781
申请日：2010-08-10
申请人： SIGNE R. ERICKSON , Charles J. Hagemeier
发明人： SIGNE R. ERICKSON , Charles J. Hagemeier
IPC分类号： A61F9/007
CPC分类号： A61F9/0017
摘要： Methods of treating disorders of the eye are disclosed. One or more substances are injected into the vitreous humor of the eye using a syringe. A needle of the syringe is inserted into the eye such that the tip of the needle is positioned inferior to the visual axis. The needle of the syringe is inserted into the eye at an injection point that is located from 3 mm to 5 mm posterior to the limbus of the eye. The tip of the needle is positioned at a depth from 1 mm to 10 mm from the retina of the eye at the injection point.
摘要翻译：公开了治疗眼睛疾病的方法。使用注射器将一种或多种物质注射到眼睛的玻璃体液中。将注射器的针插入到眼睛中，使得针的尖端位于视轴以下。注射器的针被插入眼睛中的注射点，该注射点位于眼睛边缘后方3mm至5mm处。针尖位于注射点距离眼睛视网膜1mm至10mm的深度。

2. 发明授权

US06554860B2 Foldable iris fixated intraocular lenses 失效
公开(公告)号：US06554860B2
公开(公告)日：2003-04-29
申请号：US09570721
申请日：2000-05-15
申请人： Laurent G. Hoffmann , Charles J. Hagemeier , Wilson Hsing , Donald C. Stenger , Eric T. Wilde
发明人： Laurent G. Hoffmann , Charles J. Hagemeier , Wilson Hsing , Donald C. Stenger , Eric T. Wilde
IPC分类号： A61F216
CPC分类号： A61F2/1602 , A61F2/1616
摘要： A refractive anterior chamber iris fixated intraocular lens including an optic portion having an outer peripheral edge and two or more but preferably two, three or four balanced haptic elements. Each haptic element is of a relatively narrow arch-like form. Each haptic element is also manufactured to have an inner portion and an outer portion for supporting the optic portion in a patient's eye. The inner portion of each haptic element is permanently connected to the outer peripheral edge of the optic portion. Each haptic element also includes a fixation clamp on the outer portion thereof and a central portion located between the outer portion and the inner portion.

3. 发明申请

US20110245799A1 SYSTEM AND METHOD FOR DELIVERY OF SUSPENSIONS AND OTHER MICROPARTICLE COMPOSITIONS 审中-公开
标题翻译：用于输送悬浮液和其他微生物组合物的系统和方法
公开(公告)号：US20110245799A1
公开(公告)日：2011-10-06
申请号：US13077291
申请日：2011-03-31
申请人： SIGNE R. ERICKSON , Charles J. Hagemeier , Gary A. Winchester
发明人： SIGNE R. ERICKSON , Charles J. Hagemeier , Gary A. Winchester
IPC分类号： A61M5/31 , A61M5/315
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/28 , A61M5/284
摘要： Disclosed herein are systems and methods useful for delivery of suspensions and other microparticle compositions, and, in particular, for delivering microparticles at desired dosing levels and eliminating blockages within microparticle suspensions positioned within a delivery device.
摘要翻译：本文公开了用于递送悬浮液和其它微粒组合物的系统和方法，特别是用于以期望的剂量水平递送微粒并消除位于递送装置内的微粒悬浮液内的阻塞物。

4. 发明授权

US06398809B1 Intraocular lens 失效
标题翻译：人工晶状体
公开(公告)号：US06398809B1
公开(公告)日：2002-06-04
申请号：US09548137
申请日：2000-04-12
申请人： Laurent Hoffmann , Donald C. Stenger , Eric Wilde , Charles J. Hagemeier
发明人： Laurent Hoffmann , Donald C. Stenger , Eric Wilde , Charles J. Hagemeier
IPC分类号： A61F216
CPC分类号： A61F2/1602 , A61F2002/1683
摘要： A refractive anterior chamber intraocular lens including an optic portion having an outer peripheral edge and two or more but preferably three or four haptic elements. Each haptic element is of like form. Each haptic element is also manufactured to have an inner portion and an outer portion for supporting the optic portion in a patient's eye. The inner portion of each haptic element is preferably permanently connected to the outer peripheral edge of the optic portion. Each haptic element also includes a contact button and a central portion located between the contact button and the inner portion. Each haptic is formed to have greater resistance to bending in a plane generally parallel to an eye's optical axis than in a plane generally perpendicular to the eye's optical axis. The intraocular lens is so designed to exhibit less than approximately 1.0 mm axial displacement of the optic portion along the eye's optical axis under a compression force suitable to effect a 1.0 mm in diameter compression of the intraocular lens.
摘要翻译：折射前房眼内透镜，其包括具有外周边缘和两个或更多但优选三个或四个触觉元件的光学部分。每个触觉元素都是类似的形式。每个触觉元件也被制造成具有用于支撑患者眼睛中的光学部分的内部部分和外部部分。每个触觉元件的内部部分优选地永久地连接到光学部分的外周边缘。每个触觉元件还包括接触按钮和位于触点按钮和内部之间的中心部分。每个触觉形成为在大致平行于眼睛的光轴的平面中比在大致垂直于眼睛的光轴的平面中具有更大的抗弯曲性。眼内透镜被设计成在适合于实现眼内透镜的1.0mm直径压缩的压缩力下，沿着眼睛的光轴显示小于约1.0mm的光学部分的轴向位移。

5. 发明授权

US5627162A Methods and means for control of proliferation of remnant cells following surgery 失效
标题翻译：控制手术后残留细胞增殖的方法和手段
公开(公告)号：US5627162A
公开(公告)日：1997-05-06
申请号：US374360
申请日：1995-01-18
申请人： Arlene E. Gwon , Charles J. Hagemeier
发明人： Arlene E. Gwon , Charles J. Hagemeier
IPC分类号： A61K31/715 , A61K31/728 , A61K31/737 , A61K31/70
CPC分类号： A61K31/737 , A61K31/715 , A61K31/728
摘要： The present invention relates to methods to control undesired cell proliferation of remnant cells following surgery, by applying an effective amount of at least one proteoglycan-type substrate adhesion molecule (SAM) to the site of surgery. SAMs, in particular chondroitin sulfate, hyaluronic acid, and non-toxic, pharmaceutically acceptable salts thereof, alone or in a composition form, are typically used to prevent or inhibit growth of lens-related cells in a lens capsule after surgical removal of the lens, or to prevent proliferative vitreoretinopathy following retinal reattachment procedure performed with or without vitrectomy.
摘要翻译：本发明涉及通过在手术部位施用有效量的至少一种蛋白聚糖型底物粘附分子（SAM）来控制手术后残留细胞的不需要的细胞增殖的方法。典型地使用单独或组成形式的SAM，特别是硫酸软骨素，透明质酸和无毒的药学上可接受的盐，以防止或抑制手术切除镜片后镜片胶囊中透镜相关细胞的生长，或防止在进行或不进行玻璃体切割术的视网膜再附着手术后增殖性玻璃体视网膜病变。

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