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1. 发明申请

US20090088344A1 Method Selecting Highly Specific Probes For HPV Genotype Analysis and the Probes Thereof 审中-公开
标题翻译：选择HPV基因型分析的高比例检测方法及其探针
公开(公告)号：US20090088344A1
公开(公告)日：2009-04-02
申请号：US11917263
申请日：2005-07-05
申请人： Yong-Ku Cho , Chang-Il Hwang
发明人： Yong-Ku Cho , Chang-Il Hwang
IPC分类号： C40B40/06 , G01N33/50 , C07H21/00
CPC分类号： C12Q1/708 , Y10T436/143333
摘要： A method for selecting a highly specific probe among a predetermined range of nucleotide sequences comprises: setting a group of nucleotide sequences among the predetermined range of nucleotide sequences; setting a range of nucleotide sequences in the group of nucleotide sequences; selecting first candidate probes having a certain length within the range of nucleotide sequences; selecting second candidate probes whose melting temperature with target nucleic acids for the first candidate probes is in an appropriate range; selecting third candidate probes whose melting temperature with a specific set of nucleotide sequences is lower than a hybridization temperature; and selecting fourth candidate probes, wherein a secondary structure of each fourth candidate probe has a melting temperature lower than the hybridization temperature by approximately 5° C. to approximately 10° C. and higher than a temperature that is lower than the hybridization temperature by approximately 5° C. to approximately 10° C.
摘要翻译：在预定范围的核苷酸序列中选择高度特异性探针的方法包括：在核苷酸序列的预定范围内设置一组核苷酸序列; 设置核苷酸序列组中核苷酸序列的范围; 选择在核苷酸序列范围内具有一定长度的第一候选探针; 选择第二候选探针，其第一候选探针的靶核酸的熔化温度在适当的范围内; 选择具有特定核苷酸序列的融合温度的第三候选探针低于杂交温度; 以及选择第四候选探针，其中每个第四候选探针的二级结构具有比杂交温度低约5℃至约10℃的熔解温度，并且高于低于杂交温度大约的温度 5°C至约10°C

2. 发明授权

US06469209B1 Acrylate-type fungicide 失效
标题翻译：丙烯酸酯类杀菌剂
公开(公告)号：US06469209B1
公开(公告)日：2002-10-22
申请号：US10009701
申请日：2001-12-14
申请人： Hong Lim , Bong Jin Chung , Jong Sang Chung , In Young Choi , Dae Jong Park , Chang Il Hwang
发明人： Hong Lim , Bong Jin Chung , Jong Sang Chung , In Young Choi , Dae Jong Park , Chang Il Hwang
IPC分类号： C07C23309
CPC分类号： A01N37/50
摘要： The present invention relates to novel acrylate-type N-methyl E-2-(2-methylphenyl)oxymethyl)-6-methylphenyl-glyoxylamide O-methyl oxime represented by formula (1), its preparation method and its use as fungicides. The compound of the present invention has not only stronger fungicidal effect on plant pathogens at low concentrations but also broader fungicidal spectrum than the conventional fungicides. Especially, because the compound has excellent systemic and curative effect as well as no toxicity, it can be used as an efficacious agricultural fungicide. In addition, the compound of the present invention can be useful as environmental-friendly fungicide capable of causing less environmental pollution fungicide due to its strong fungicidal effect at low concentrations.
摘要翻译：本发明涉及由式（1）表示的新型丙烯酸酯型N-甲基E-2-（2-甲基苯基）氧甲基）-6-甲基苯基 - 乙醛酰胺O-甲基肟，其制备方法及其作为杀真菌剂的用途。本发明的化合物不仅具有比常规杀真菌剂在低浓度下对植物病原体更强的杀真菌作用，而且具有更广泛的杀真菌作用。特别是因为该化合物具有优异的全身和治疗效果以及无毒性，因此可用作有效的农药杀菌剂。此外，本发明的化合物由于其在低浓度下具有强烈的杀真菌作用，因此可用作能够减少环境污染杀真菌剂的环保杀真菌剂。

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