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    • 3. 发明申请
    • Open loop deep brain stimulation system for the treatment of Parkinson's Disease or other disorders
    • 开环深脑刺激系统用于治疗帕金森病或其他疾病
    • US20050055064A1
    • 2005-03-10
    • US10970878
    • 2004-10-22
    • Paul MeadowsCarla Woods
    • Paul MeadowsCarla Woods
    • A61N1/05A61N1/36A61N1/18
    • A61N1/36082A61N1/0534A61N1/0539
    • A deep brain stimulation (DBS) system (10) provides a multiplicity of stimulation channels through which electrical stimuli may be delivered deep within the brain of a patient. The DBS system is powered by a rechargeable battery (27). In one embodiment, the system has four channels driving sixteen electrodes (32). The DBS system is easily programmed for use by a clinician using a clinician programming system (60), and further affords a simple but highly advanced hand held programmer (50) control interface through which the patient may easily change stimulation parameters within acceptable limits. The DBS system (10) includes a small, implantable pulse generator (20) that is small enough to be implanted directly in the cranium of the patient, thereby eliminating the long lead wires and tunneling procedures that have been used in the past. The implantable pulse generator provides electrical stimuli in an open-loop fashion as defined by the stimulation parameters. Further, the DBS system allows up to two electrode arrays (30, 30′) to be attached to the implantable pulse generator (20), thereby eliminating the requirement for implanting two independent implantable pulse generators for bilateral stimulation of deep brain structures.
    • 深部脑刺激(DBS)系统(10)提供了多个刺激通道,通过电刺激通道,电刺激可以在患者的脑部内深深地传递。 DBS系统由可充电电池(27)供电。 在一个实施例中,系统具有驱动十六个电极(32)的四个通道。 DBS系统易于编程以供临床医生使用临床医师编程系统(60)使用,并进一步提供简单但高度先进的手持编程器(50)控制接口,通过该控制接口,患者可以容易地将刺激参数改变到可接受的限度内。 DBS系统(10)包括小到可植入的脉冲发生器(20),该脉冲发生器(20)足够小以直接植入患者的颅骨中,从而消除过去已经使用的长引线和隧道过程。 可植入脉冲发生器以由刺激参数定义的开环方式提供电刺激。 此外,DBS系统允许多达两个电极阵列(30,30')附接到可植入脉冲发生器(20),从而消除了植入两个独立的可植入脉冲发生器用于双侧刺激深部脑结构的要求。
    • 4. 发明申请
    • PATIENT PROGRAMMER FOR IMPLANTABLE DEVICES
    • 用于可植入装置的患者编程器
    • US20070293914A1
    • 2007-12-20
    • US11625281
    • 2007-01-19
    • Carla WoodsJames ThackerDavid Peterson
    • Carla WoodsJames ThackerDavid Peterson
    • A61N1/02
    • A61N1/36071A61N1/0551A61N1/0553A61N1/36185A61N1/37235A61N1/37241A61N1/37247A61N1/37252A61N1/3787
    • The invention is a system and method for detecting the status of a rechargeable battery included within an implantable medical device. The medical device can incorporate a status indicator which signals the user concerning the battery status, e.g., low battery level. The signal may be audible or it may arise from an electrical stimulation that is perceptually distinguished from the operative, therapeutic stimulation. The external programmer may also incorporate a second battery status indicator that is visual, audible, or physically felt. Battery status data may be conveyed on visual displays on the external programmer by uploading this information from the medical device using a bidirectional telemetry link. Such battery status data are helpful to the user to indicate when the battery should be recharged and to the clinician to monitor patient compliance and to determine end-of-useful life of the rechargeable battery.
    • 本发明是一种用于检测包括在可植入医疗装置内的可再充电电池的状态的系统和方法。 医疗设备可以包括状态指示器,其向用户通知有关电池状态的信号,例如电池电量低。 该信号可能是可听见的,或者它可能由感觉上区别于手术治疗刺激的电刺激引起。 外部编程器还可以包括视觉,听觉或物理感觉的第二电池状态指示器。 电池状态数据可以通过使用双向遥测链路从医疗设备上传该信息而在外部编程器上的视觉显示器上传送。 这样的电池状态数据有助于用户指示电池何时被充电,并且临床医师监测患者的依从性并确定可再充电电池的使用寿命。
    • 5. 发明申请
    • RECHARGEABLE SPINAL CORD STIMULATION SYSTEM
    • 可充电脊髓刺激系统
    • US20070276450A1
    • 2007-11-29
    • US11625283
    • 2007-01-20
    • Paul MeadowsCarla WoodsDavid PetersonJoey ChenDavid Payne
    • Paul MeadowsCarla WoodsDavid PetersonJoey ChenDavid Payne
    • A61N1/05
    • A61N1/37252A61N1/0553A61N1/36071A61N1/36185A61N1/37241A61N1/37247A61N1/3787H01H85/201H01H85/32
    • A spinal cord stimulation (SCS) system includes multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (IPG) which channels can provide concurrent, but unique stimulation fields, permitting virtual electrodes to be realized. The SCS system includes a replenishable power source (e.g., rechargeable battery), that may be recharged using transcutaneous power transmissions between antenna coil pairs. An external charger unit, having its own rechargeable battery can be used to charge the IPG replenishable power source. A real-time clock can provide an auto-run schedule for daily stimulation. An included bi-directional telemetry link in the system informs the patient or clinician the status of the system, including the state of charge of the IPG battery. Other processing circuitry in the IPG allows electrode impedance measurements to be made. Further circuitry in the external battery charger can provide alignment detection for the coil pairs.
    • 脊髓刺激(SCS)系统包括在可植入脉冲发生器(IPG)内的多个电极,多个独立可编程的刺激通道,其通道可以提供同时但独特的刺激场,允许实现虚拟电极。 SCS系统包括可补充电源(例如,可充电电池),其可以使用天线线圈对之间的经皮功率传输进行再充电。 可以使用具有自己的可充电电池的外部充电器单元为IPG可补充电源充电。 实时时钟可以提供每日刺激的自动运行时间表。 系统中包括的双向遥测连接通知患者或临床医生系统的状态,包括IPG电池的充电状态。 IPG中的其他处理电路允许进行电极阻抗测量。 外部电池充电器中的进一步电路可以为线圈对提供对准检测。
    • 7. 发明申请
    • Method for programming implantable device
    • 编程植入式装置的方法
    • US20050245987A1
    • 2005-11-03
    • US11105643
    • 2005-04-13
    • Carla WoodsJames ThackerDavid PetersonHolly SegelSusan FordMargaret TheriotKerry Bradley
    • Carla WoodsJames ThackerDavid PetersonHolly SegelSusan FordMargaret TheriotKerry Bradley
    • A61N1/18A61N1/34A61N1/372
    • A61N1/36071A61N1/08A61N1/36185A61N1/37241A61N1/37247
    • A method for selecting Spinal Cord Stimulation (SCS) stimulation parameter sets guides a clinician towards an effective set of stimulation parameters. The clinician first evaluates the effectiveness of a small number of trial stimulation parameters sets from a Measurement Table comprising for example, four stimulation parameter sets. Based on the patient's assessment, the trial stimulation parameter sets are ranked. Then the clinician selects a starting or benchmark row in a Steering Table corresponding to the highest ranked trial stimulation parameter set. The clinician moves either up or down form the starting row, testing consecutive parameter sets. The clinician continues as long as the patient indicates that the stimulation results are improving. When a local optimum is found, the clinician returns to the benchmark row, and tests in the opposite direction for another local optimum. If an acceptable set of stimulation parameters is found, the selection process is complete. If an acceptable set is not found, a new starting row in the Steering Table is selected based on the next ranked trial set from the Measurement Table, and the process of searching for local optima is repeated.
    • 用于选择脊髓刺激(SCS)刺激参数组的方法引导临床医生朝向有效的一组刺激参数。 临床医生首先从包括例如四个刺激参数组的测量表中评估少量试验刺激参数集的有效性。 根据患者的评估,对试验刺激参数集进行排序。 然后,临床医生在对应于最高排名的试验刺激参数集的转向表中选择起始或基准行。 临床医生从起始行向上或向下移动,测试连续的参数集。 只要患者表明刺激结果正在改善,临床医生就会继续进行。 当找到局部最佳值时,临床医生返回到基准行,并以相反方向测试另一个局部最佳值。 如果发现可接受的一组刺激参数,则选择过程完成。 如果没有找到可接受的集合,则基于从测量表中的下一个排序的试验集,选择转向表中的新起始行,并且重复搜索局部最优的处理。