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1. 发明授权

US09223745B2 Flexible database and iterative spatial search process 有权
标题翻译：灵活的数据库和迭代空间搜索过程
公开(公告)号：US09223745B2
公开(公告)日：2015-12-29
申请号：US13351828
申请日：2012-01-17
申请人： Lucas Neal Joppa , Andrew Bryan Roberts , Richard James Williams
发明人： Lucas Neal Joppa , Andrew Bryan Roberts , Richard James Williams
IPC分类号： G06F15/16 , G06F17/30
CPC分类号： G06F15/16 , G06F17/30241
摘要： A flexible database and iterative spatial search process is described. In an embodiment, a flexible database server is described which takes input queries in the form of XML strings describing a search specification and parses them using a stored procedure. Searching is performed by generating a temporary table for each term in the search specification and then comparing the temporary tables to pre-existing tables within the database to identify datasets that meet the search specification. An application is also described which generates the XML string in response to user input and which displays the results to a user. The application provides a user interface which enables users to select attributes of results, such as the spatial data associated with a dataset, to include in a second search specification and to trigger this new search.
摘要翻译：描述了灵活的数据库和迭代空间搜索过程。在一个实施例中，描述了以描述搜索规范的XML字符串的形式进行的输入查询并且使用存储过程进行解析的灵活的数据库服务器。通过为搜索规范中的每个术语生成临时表，然后将临时表与数据库中的现有表进行比较，以识别符合搜索规范的数据集来执行搜索。还描述了响应于用户输入生成XML字符串并将结果显示给用户的应用程序。应用程序提供了一个用户界面，使用户能够选择结果的属性，例如与数据集相关联的空间数据，以包含在第二个搜索规范中并触发此新的搜索。

2. 发明申请

US20100144759A1 NOVEL N-(FLUORO-PYRAZINYL)-PHENYLSULFONAMIDES AS MODULATORS OF CHEMOKINE RECEPTOR CCR4 审中-公开
标题翻译：新型N-（氟代 - 吡啶基） - 苯基磺酰胺作为化合物受体CCR4的调节剂
公开(公告)号：US20100144759A1
公开(公告)日：2010-06-10
申请号：US12633548
申请日：2009-12-08
申请人： David CHESHIRE , Nicholas Kindon , Antonio Mete , Bryan Roberts
发明人： David CHESHIRE , Nicholas Kindon , Antonio Mete , Bryan Roberts
IPC分类号： A61K31/4965 , C07D241/22 , A61P11/06 , A61P11/00
CPC分类号： C07D241/22
摘要： The invention provides N-(fluoro-pyrazinyl)-phenylsulfonamides of formula (I) wherein R1-R5 are as defined in the specification; processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy
摘要翻译：本发明提供式（I）的N-（氟 - 吡嗪基） - 苯基磺酰胺，其中R 1 -R 5如说明书中所定义; 制备中使用的方法和中间体，含有它们的药物组合物及其在治疗中的用途

3. 发明授权

US07650538B2 Identifying temporal ambiguity in an aggregated log stream 失效
标题翻译：识别聚合日志流中的时间歧义
公开(公告)号：US07650538B2
公开(公告)日：2010-01-19
申请号：US12048501
申请日：2008-03-14
申请人： Fred Allison Bower, III , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
发明人： Fred Allison Bower, III , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
IPC分类号： G06F11/00
CPC分类号： G06F11/3636 , G06F11/0706 , G06F11/0781 , G06F11/3476 , G06F2201/86
摘要： A method and system for ordering and aggregating log streams. Log streams for events from different sources are received. If different sources have different recording cycles, or time epochs, that lead to different temporal granularities, then all of the log streams are combined into a single time epoch that is equal to the longest time epoch. Log streams from sources having shorter time epochs continue to retain information about their original time epochs, in order to retain information about the order of the events in those log streams. The log streams are reordered, both before and after being integrated into the aggregate log, by acquiring additional data from the different sources, thus permitting the likely cause/effect relationship between events.
摘要翻译：用于排序和聚合日志流的方法和系统。收到来自不同来源的事件的日志流。如果不同的源具有不同的记录周期或时间周期，导致不同的时间粒度，则所有对数流被组合成等于最长时间时间的单个时间周期。来自具有较短时间纪元的源的日志流继续保留关于其原始时间纪元的信息，以便保留关于这些日志流中的事件顺序的信息。通过从不同来源获取附加数据，将日志流重新排序，在集成日志之前和之后，从而允许事件之间的可能的因果关系。

4. 发明申请

US20090023746A1 COMPOUNDS AND THEIR USES 707 失效
标题翻译：化合物及其用途707
公开(公告)号：US20090023746A1
公开(公告)日：2009-01-22
申请号：US12062718
申请日：2008-04-04
申请人： Matthew Hallam , Barrie Martin , Piotr Raubo , Bryan Roberts , Stephen St-Gallay , Paul Willis
发明人： Matthew Hallam , Barrie Martin , Piotr Raubo , Bryan Roberts , Stephen St-Gallay , Paul Willis
IPC分类号： A61K31/4725 , A61P11/00 , C07D217/24 , C07D401/10 , C07D401/14 , A61K31/496 , A61K31/472
CPC分类号： C07D217/24 , C07D217/26 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D487/08
摘要： The present invention relates to isoquinolinone derivatives of formula (I): wherein R1, R2, R3, R4, R5, R6 and R7 are as herein defined; processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明涉及式（I）的异喹啉酮衍生物：其中R1，R2，R3，R4，R5，R6和R7如本文所定义; 其制备方法，含有它们的药物组合物及其在治疗中的用途。

5. 发明授权

US07380173B2 Identifying temporal ambiguity in a aggregated log stream 有权
标题翻译：识别聚合日志流中的时间歧义
公开(公告)号：US07380173B2
公开(公告)日：2008-05-27
申请号：US10910016
申请日：2004-08-03
申请人： Fred Allison Bower, III , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
发明人： Fred Allison Bower, III , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
IPC分类号： G06F11/00
CPC分类号： G06F11/3636 , G06F11/0706 , G06F11/0781 , G06F11/3476 , G06F2201/86
摘要： A method and system for ordering and aggregating log streams. Log streams for events from different sources are received. If different sources have different recording cycles, or time epochs, that lead to different temporal granularities, then all of the log streams are combined into a single time epoch that is equal to the longest time epoch. Log streams from sources having shorter time epochs continue to retain information about their original time epochs, in order to retain information about the order of the events in those log streams. The log streams are re-ordered, both before and after being integrated into the aggregate log, by acquiring additional data from the different sources, thus permitting the likely cause/effect relationship between events.
摘要翻译：用于排序和聚合日志流的方法和系统。收到来自不同来源的事件的日志流。如果不同的源具有不同的记录周期或时间周期，导致不同的时间粒度，则所有对数流被组合成等于最长时间时间的单个时间周期。来自具有较短时间纪元的源的日志流继续保留关于其原始时间纪元的信息，以便保留关于这些日志流中的事件顺序的信息。通过从不同来源获取附加数据，将日志流重新排序，在前后被集成到聚合日志中，从而允许事件之间的可能的因果关系。

6. 发明申请

US20150064106A1 Biodegradable Polyphosphazenes Containing Pyrrolidone Side Groups 审中-公开
标题翻译：含有吡咯烷酮侧基的可生物降解聚磷腈
公开(公告)号：US20150064106A1
公开(公告)日：2015-03-05
申请号：US14535562
申请日：2014-11-07
申请人： Alexander Andrianov , Bryan Roberts
发明人： Alexander Andrianov , Bryan Roberts
IPC分类号： A61K47/34 , A61L29/06 , A61L27/34 , A61L31/06 , A61L31/10 , A61L27/18 , C08G79/02 , A61L29/08
CPC分类号： A61K47/34 , A61L27/18 , A61L27/34 , A61L29/06 , A61L29/085 , A61L31/06 , A61L31/10 , C08L85/02
摘要： Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed.
摘要翻译：公开了含有吡咯烷酮侧基的可生物降解的聚磷腈聚合物，以及这种聚磷腈聚合物的生物医学应用。

7. 发明申请

US20140030320A1 Biodegradable Polyphosphazenes Containing Pyrrolidone Side Groups 审中-公开
标题翻译：含有吡咯烷酮侧基的可生物降解聚磷腈
公开(公告)号：US20140030320A1
公开(公告)日：2014-01-30
申请号：US14043161
申请日：2013-10-01
申请人： Alexander Andrianov , Bryan Roberts
发明人： Alexander Andrianov , Bryan Roberts
IPC分类号： A61K47/34
CPC分类号： A61K47/34 , A61L27/18 , A61L27/34 , A61L27/58 , A61L29/06 , A61L29/085 , A61L29/148 , A61L31/06 , A61L31/10 , A61L31/148 , C08G79/025 , C08L25/18 , C08L39/06 , C08L85/02 , C08L2205/05 , Y02A50/466 , Y10T428/139 , C08L2666/04
摘要： Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed.
摘要翻译：公开了含有吡咯烷酮侧基的可生物降解的聚磷腈聚合物，以及这种聚磷腈聚合物的生物医学应用。

8. 发明申请

US20080293742A1 Novel N-(Fluoro-Pyrazinyl)-Phenylsulfonamides as Modulators of Chemokine Receptor Ccr4 审中-公开
标题翻译：新型N-（氟 - 吡嗪基） - 苯磺酰胺作为趋化因子受体Ccr4的调节剂
公开(公告)号：US20080293742A1
公开(公告)日：2008-11-27
申请号：US12096513
申请日：2006-12-11
申请人： David Cheshire , Nicholas Kindon , Antonio Mete , Bryan Roberts
发明人： David Cheshire , Nicholas Kindon , Antonio Mete , Bryan Roberts
IPC分类号： A61K31/4965 , C07D241/22 , A61P11/06
CPC分类号： C07D241/22
摘要： The invention provides N-(fluoro-pyrazinyl)-phenylsulfonamides of formula (I) wherein R1-R5 are as defined in the specification; processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy
摘要翻译：本发明提供式（I）的N-（氟 - 吡嗪基） - 苯基磺酰胺，其中R 1 -R 5如说明书中所定义; 制备中使用的方法和中间体，含有它们的药物组合物及其在治疗中的用途

9. 发明申请

US20080162083A1 Identifying Temporal Ambiguity in an Aggregated Log Stream 失效
标题翻译：识别聚合日志流中的时间歧义
公开(公告)号：US20080162083A1
公开(公告)日：2008-07-03
申请号：US12048384
申请日：2008-03-14
申请人： Fred Allison Bower , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
发明人： Fred Allison Bower , Rodney Hugh Brown , Tushar Dasharath Fadale , Thomas James Fox , Richard Edwin Harper , David Bryan Roberts , Ketan K. Shah
IPC分类号： G06F15/00
CPC分类号： G06F11/3636 , G06F11/0706 , G06F11/0781 , G06F11/3476 , G06F2201/86
摘要： A method and system for ordering and aggregating log streams. Log streams for events from different sources are received. If different sources have different recording cycles, or time epochs, that lead to different temporal granularities, then all of the log streams are combined into a single time epoch that is equal to the longest time epoch. Log streams from sources having shorter time epochs continue to retain information about their original time epochs, in order to retain information about the order of the events in those log streams. The log streams are re-ordered, both before and after being integrated into the aggregate log, by acquiring additional data from the different sources, thus permitting the likely cause/effect relationship between events.
摘要翻译：用于排序和聚合日志流的方法和系统。收到来自不同来源的事件的日志流。如果不同的源具有不同的记录周期或时间周期，导致不同的时间粒度，则所有对数流被组合成等于最长时间时间的单个时间周期。来自具有较短时间纪元的源的日志流继续保留关于其原始时间纪元的信息，以便保留关于这些日志流中的事件顺序的信息。通过从不同来源获取附加数据，将日志流重新排序，在前后被集成到聚合日志中，从而允许事件之间的可能的因果关系。

10. 发明申请

US20060025423A1 N-pyrazinyl-phenylsulphonamides and their use in the treatment of chemokine mediated diseases 失效
标题翻译： N-吡嗪基 - 苯基磺酰胺及其在治疗趋化因子介导的疾病中的应用
公开(公告)号：US20060025423A1
公开(公告)日：2006-02-02
申请号：US10501510
申请日：2003-01-14
申请人： Andrew Baxter , Timothy Johnson , Nicholas Kindon , Bryan Roberts , Michael Stocks
发明人： Andrew Baxter , Timothy Johnson , Nicholas Kindon , Bryan Roberts , Michael Stocks
IPC分类号： A61K31/4965 , C07D241/02
CPC分类号： C07D231/12 , C07D233/56 , C07D241/22 , C07D249/08 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07F7/0812
摘要： The invention provides N-pyrazinyl-phenyl-sulphonamides of formula (I) for use in the treatment of chemokine mediated diseases. Particularly inflammatory diseases, such as asthma.
摘要翻译：本发明提供了用于治疗趋化因子介导的疾病的式（I）的N-吡嗪基 - 苯基 - 磺酰胺。特别是炎性疾病，如哮喘。

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