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1. 发明申请

US20150314100A1 SYSTEMS AND DEVICES FOR GENERATING NITRIC OXIDE 有权
标题翻译：用于生成氮氧化物的系统和装置
公开(公告)号：US20150314100A1
公开(公告)日：2015-11-05
申请号：US14612266
申请日：2015-02-02
申请人： David H. Fine , Bryan Johnson , Gregory Vasquez
发明人： David H. Fine , Bryan Johnson , Gregory Vasquez
IPC分类号： A61M16/12 , A61M16/16 , A61M16/10
CPC分类号： A61M16/12 , A61M16/10 , A61M16/104 , A61M16/105 , A61M16/107 , A61M16/1075 , A61M16/109 , A61M16/16 , A61M2202/0275 , A62B7/08 , A62B21/00 , C01B21/24
摘要： Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.
摘要翻译：本文公开了用于产生一氧化氮的各种系统和装置。根据一个实施例，该装置包括具有与主体定位的入口，出口和多孔固体基体的主体。多孔固体基质涂覆有抗氧化剂的水溶液，其中入口构造成接收气流并且将气流与通过固体基质的出口流体连通，将气流中的二氧化氮转化为一氧化氮。多孔固体基质允许该装置以任何取向使用。此外，多孔固体基质提供了适合于抵抗振动和滥用的刚性结构，而不会影响装置的功能。

2. 发明授权

US08701657B2 Systems for generating nitric oxide 有权
标题翻译：产生一氧化氮的系统
公开(公告)号：US08701657B2
公开(公告)日：2014-04-22
申请号：US12541141
申请日：2009-08-13
申请人： David H. Fine , Gregory Vasquez , Bryan Johnson
发明人： David H. Fine , Gregory Vasquez , Bryan Johnson
IPC分类号： A61M15/00 , A61M16/00 , A62B7/08 , A62B21/00
CPC分类号： A61M16/12 , A61M16/0051 , A61M16/10 , A61M16/16 , A61M16/20 , A61M2016/102 , A61M2202/0275 , C01B21/24
摘要： In one aspect, a system for delivering nitric oxide to a patient can include a first gas source including nitrogen dioxide mixed in air or oxygen, a second gas source supplying compressed air, a ventilator coupled to the first and second gas sources, where the ventilator can be resistant to nitrogen dioxide, and where the ventilator provides a gas flow having a proper amount of nitrogen dioxide, one or more conversion devices operably coupled to the ventilator, where the conversion devices covert nitrogen dioxide into nitric oxide, and a patient interface operably coupled to the conversion devices, where the patient interface delivers nitric oxide to the patient.
摘要翻译：一方面，用于向患者输送一氧化氮的系统可以包括第一气体源，其包括混合在空气或氧气中的二氧化氮，提供压缩空气的第二气体源，耦合到第一和第二气体源的呼吸机，其中呼吸机可以耐二氧化氮，并且其中呼吸机提供具有适当量二氧化氮的气流，一个或多个可转换装置可操作地耦合到呼吸机的转换装置，其中转换装置将二氧化氮隐藏成一氧化氮，以及患者接口可操作地耦合到转换装置，其中患者界面向患者输送一氧化氮。

3. 发明授权

US08646445B2 Nitric oxide delivery system 有权
标题翻译：一氧化氮输送系统
公开(公告)号：US08646445B2
公开(公告)日：2014-02-11
申请号：US12951811
申请日：2010-11-22
申请人： David H. Fine , Gregory Vasquez , Bryan Johnson , Jody Fuller , Ryan Denton
发明人： David H. Fine , Gregory Vasquez , Bryan Johnson , Jody Fuller , Ryan Denton
IPC分类号： A61M16/10 , A61M16/00 , H05B3/00
CPC分类号： A61M16/104 , A61K33/00 , A61M16/0057 , A61M16/0066 , A61M16/1075 , A61M16/12 , A61M2016/102 , A61M2202/0208 , A61M2202/0275 , A61M2205/8206
摘要： An ambulatory or stationary device for delivery of a therapeutic amount of nitric oxide to an individual's lungs.
摘要翻译：用于将治疗量的一氧化氮递送至个体肺的移动或固定装置。

4. 发明申请

US20120321970A1 METAL-AIR CELL WITH ION EXCHANGE MATERIAL 有权
标题翻译：具有离子交换材料的金属空气细胞
公开(公告)号：US20120321970A1
公开(公告)日：2012-12-20
申请号：US13526342
申请日：2012-06-18
申请人： Cody A. Friesen , Derek WOLFE , Paul Bryan JOHNSON
发明人： Cody A. Friesen , Derek WOLFE , Paul Bryan JOHNSON
IPC分类号： H01M10/0565 , H01M8/10 , B01J39/18 , B01J39/20 , H01M8/02 , H01M10/056
CPC分类号： H01M12/06 , H01M12/08 , H01M2300/0082 , Y02E60/128 , Y02E60/522
摘要： Embodiments of the invention are related to anion exchange membranes used in electrochemical metal-air cells in which the membranes function as the electrolyte material, or are used in conjunction with electrolytes such as ionic liquid electrolytes.
摘要翻译：本发明的实施方案涉及用于电化学金属 - 空气电池中的阴离子交换膜，其中膜用作电解质材料，或与电解质如离子液体电解质结合使用。

5. 发明申请

US20120251399A1 CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) 有权
公开(公告)号：US20120251399A1
公开(公告)日：2012-10-04
申请号：US13436018
申请日：2012-03-30
申请人： David H. Fine , David P. Rounbehler , Gregory Vasquez , Bryan Johnson
发明人： David H. Fine , David P. Rounbehler , Gregory Vasquez , Bryan Johnson
IPC分类号： B01J7/00
CPC分类号： B01J12/007 , A61K33/00 , A61M16/10 , A61M16/122 , A61M2016/1025 , A61M2202/0007 , A61M2202/0078 , A61M2202/0275 , A61M2205/07 , A61M2205/12 , A62B7/08 , C01B21/24
摘要： A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

6. 发明申请

US20120093948A1 Nitric Oxide Treatments 审中-公开
标题翻译：一氧化氮治疗
公开(公告)号：US20120093948A1
公开(公告)日：2012-04-19
申请号：US13310359
申请日：2011-12-02
申请人： David H. FINE , Robert F. ROSCIGNO , Gregory VASQUEZ , Bryan JOHNSON , Ryan DENTON
发明人： David H. FINE , Robert F. ROSCIGNO , Gregory VASQUEZ , Bryan JOHNSON , Ryan DENTON
IPC分类号： A61K33/00 , A61P9/12 , A61P11/00 , A61P25/34 , A61P7/00 , A61P9/04 , A61P13/12 , A61P25/00 , A61P9/00
CPC分类号： A61M16/10 , A61M16/1055 , A61M16/107 , A61M2202/0275 , B01D53/0415 , B01D53/565 , B01D2251/21 , B01D2253/102 , B01D2253/106 , B01D2256/00 , B01D2257/404 , B01D2259/4533 , C01B21/24
摘要： Portable and pure nitric oxide delivery systems can be used to treat a variety of patient conditions.
摘要翻译：便携式和纯净的一氧化氮输送系统可用于治疗各种患者病情。

7. 发明申请

US20050193616A1 Fishing rod strike sensor 审中-公开
标题翻译：钓鱼竿传感器
公开(公告)号：US20050193616A1
公开(公告)日：2005-09-08
申请号：US10790743
申请日：2004-03-03
申请人： Bryan Johnson
发明人： Bryan Johnson
IPC分类号： A01K87/00 , A01K97/12 , G01L1/22
CPC分类号： A01K97/125 , A01K87/007
摘要： The fishing rod strike sensor provides an audible and visual indication of a fish striking a hook or lure suspended from a fishing rod by a fishing line. A flexible sensor, such as a flexible resistor, extends along the fishing rod, flexing along with the fishing rod. As the sensor flexes, an electrical characteristic of the sensor, such as its resistance, changes according to the degree of flex. An electronic circuit activates an alarm when the electrical characteristic varies beyond a threshold. The electrical circuit is adjustable to set the alarm threshold. A “window” threshold is employed whereby an alarm can be sounded both when a fish pulls on the line when taking the hook, and when a fish takes the hook in a manner that decreases the pull on the line.
摘要翻译：钓鱼竿打击传感器提供了一条鱼的醒目的视觉指示，一条钓鱼钓鱼的钓鱼钩或一条钓鱼线从钓竿悬挂的诱饵。柔性传感器，例如柔性电阻器，沿着钓鱼杆延伸，与钓鱼竿一起弯曲。当传感器弯曲时，传感器的电气特性（如其电阻）根据挠曲程度而变化。当电气特性变化超过阈值时，电子电路激活报警。电路可调，可设定报警阈值。使用“窗口”阈值，当钓鱼时在钓鱼时在钓鱼线上拉动时，以及当钓鱼以减少线路上拉力的方式时，可以发出警报。

8. 发明授权

US11570975B2 Fishing aid device 有权
公开(公告)号：US11570975B2
公开(公告)日：2023-02-07
申请号：US16397654
申请日：2019-04-29
申请人： Bryan Johnson
发明人： Bryan Johnson
IPC分类号： A01K87/00 , A01K87/04 , A01K85/01
摘要： A fishing aid device that is a miniature size and doesn't need a battery. The fishing aid device includes a housing; a fishing aid member disposed in the housing; and an actuating assembly disposed in the housing for energizing the fishing aid member.

9. 发明授权

US08887720B2 Delivery of ultra pure nitric oxide (NO) 有权
标题翻译：超纯氧化氮（NO）
公开(公告)号：US08887720B2
公开(公告)日：2014-11-18
申请号：US13094535
申请日：2011-04-26
申请人： David H. Fine , Gregory Vasquez , Bryan Johnson , Ryan Denton , Lucas G. Gamero
发明人： David H. Fine , Gregory Vasquez , Bryan Johnson , Ryan Denton , Lucas G. Gamero
IPC分类号： A61M16/10 , C01B21/24 , A61M16/12 , A61M16/00 , A61M16/06
CPC分类号： A61M16/122 , A61M16/0666 , A61M16/10 , A61M16/105 , A61M16/1055 , A61M16/107 , A61M16/1075 , A61M16/12 , A61M2016/0027 , A61M2016/102 , A61M2202/0266 , A61M2202/0275 , A61M2202/03 , A61M2205/0238 , A61M2205/18 , A61M2205/3368 , A61M2205/3653 , A61M2205/7518 , A61M2205/8206 , A61M2207/10 , A61M2209/088 , C01B21/24
摘要： A system for delivering a therapeutic amount of nitric oxide can include a reservoir including a restrictor with a length of at least 0.5 inch and at most 2 inches covered by a metal sheath, a gas supply, and a delivery conduit. A delivery conduit can include at least one cartridge and a patient interface. The at least one cartridge can include a surface-active material and a reducing agent.
摘要翻译：用于递送治疗量的一氧化氮的系统可以包括储存器，其包括由金属护套，气体供应和输送管道覆盖的至少0.5英寸和至多2英寸的长度的限制器。输送管道可以包括至少一个药筒和患者接口。所述至少一个筒可以包括表面活性材料和还原剂。

10. 发明授权

US08607785B2 Systems and devices for generating nitric oxide 有权
公开(公告)号：US08607785B2
公开(公告)日：2013-12-17
申请号：US12541137
申请日：2009-08-13
申请人： David H. Fine , Bryan Johnson , Gregory Vasquez
发明人： David H. Fine , Bryan Johnson , Gregory Vasquez
IPC分类号： A61M15/00 , A61M16/00 , A62B7/08 , A62B21/00
CPC分类号： A61M16/12 , A61M16/10 , A61M16/104 , A61M16/105 , A61M16/107 , A61M16/1075 , A61M16/109 , A61M16/16 , A61M2202/0275 , A62B7/08 , A62B21/00 , C01B21/24
摘要： Various systems and devices for generating nitric oxide are disclosed herein. According to one embodiment, the device includes a body having an inlet, an outlet, and a porous solid matrix positioned with the body. The porous solid matrix is coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the solid matrix to convert nitrogen dioxide in the gas flow into nitric oxide. The porous solid matrix allows the device to be used in any orientation. Additionally, the porous solid matrix provides a rigid structure suitable to withstand vibrations and abuse without compromising device functionality.

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