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1. 发明申请

US20050222117A1 Chlorophyll and its derivatives for cancer photodynamic therapy 审中-公开
标题翻译：叶绿素及其衍生物用于癌症光动力治疗
公开(公告)号：US20050222117A1
公开(公告)日：2005-10-06
申请号：US11007325
申请日：2004-12-09
申请人： Yih-Chih Hsu , Wen-Tyng Li , Jeffrey Lin , Bor-Iuan Jan , Tzu-I Wu , Jih-Shen Wen , Chi-Ming Yang
发明人： Yih-Chih Hsu , Wen-Tyng Li , Jeffrey Lin , Bor-Iuan Jan , Tzu-I Wu , Jih-Shen Wen , Chi-Ming Yang
IPC分类号： A61K31/409 , A61K31/555
CPC分类号： A61K31/409 , A61K41/0071 , A61K49/0036
摘要： The present invention relates to a method for treating liver cancer or oral cancer through photodynamic therapy, comprising administrating a subject in need thereof an effective amount of formula I, formula □, formula III or formula IV, which could release reactive oxygen species to inhibit the growth of cancer cells, which comprise with formulas as described in the specification, wherein R1 is an alkyl or an aldehyde with carbon atoms no more than 2; the cancer is liver cancer or oral cancer.
摘要翻译：本发明涉及通过光动力疗法治疗肝癌或口腔癌的方法，包括给予有需要的受试者有效量的式I，式□，式III或式IV，其可释放活性氧以抑制由说明书中所述的式所组成的癌细胞的生长，其中R1是碳原子数不超过2的烷基或醛; 癌症是肝癌或口腔癌。

2. 发明授权

US06960468B2 On-spot hydrophilic enhanced slide and preparation thereof 有权
标题翻译：现场亲水增强滑片及其制备
公开(公告)号：US06960468B2
公开(公告)日：2005-11-01
申请号：US10136357
申请日：2002-05-02
申请人： Bor-Iuan Jan , Jia-Huey Tsao , Chih-Wei Ho , Yu-Ching Liu , Chao-Chi Pan , Zu-Sho Chow , Yao-Sung Chang , Cheng-Tao Wu , Wen-Hsun Kuo
发明人： Bor-Iuan Jan , Jia-Huey Tsao , Chih-Wei Ho , Yu-Ching Liu , Chao-Chi Pan , Zu-Sho Chow , Yao-Sung Chang , Cheng-Tao Wu , Wen-Hsun Kuo
IPC分类号： C40B40/06 , C40B40/10 , C40B60/14 , G01N33/545 , G02B21/34 , C12M1/34 , C07H21/02 , G01N33/53
CPC分类号： B82Y30/00 , B01J2219/00387 , B01J2219/00527 , B01J2219/00576 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00619 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , C40B40/06 , C40B40/10 , C40B60/14 , G01N33/545 , G02B21/34 , Y10T436/143333
摘要： The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.
摘要翻译：本发明公开了一种现场亲水增强载玻片/微阵列。该制备方法涉及通过共混，接枝或共聚疏水材料和带有官能团的化合物如酸酐，酰亚胺，环状酰胺和环状酯制备的疏水性共聚物，以及将疏水性共聚物应用于有机或无机底物。所得到的载片具有现场亲水/疏水动态转化的性质，以及用于制备高密度和高效率生物芯片/微阵列的现场亲水增强。

3. 发明授权

US06528291B1 Activated inorganic slide having aldehyde groups deposited by plasma deposition 有权
标题翻译：通过等离子体沉积沉积醛基的活性无机载片
公开(公告)号：US06528291B1
公开(公告)日：2003-03-04
申请号：US09658945
申请日：2000-09-11
申请人： Zu-Sho Chow , Jia-Huey Tsao , Wen-Hsun Kuo , Chih-Wei Ho , Bor-Iuan Jan , Chao-Chi Pan , Yao-Sung Chang , Cheng-Tao Wu , Yu-Ching Liu
发明人： Zu-Sho Chow , Jia-Huey Tsao , Wen-Hsun Kuo , Chih-Wei Ho , Bor-Iuan Jan , Chao-Chi Pan , Yao-Sung Chang , Cheng-Tao Wu , Yu-Ching Liu
IPC分类号： C12N1114
CPC分类号： B01J19/0046 , B01J2219/00274 , B01J2219/00576 , B01J2219/00677 , G01N33/54353 , G01N33/545 , G01N33/551 , G01N33/552 , Y10S530/811 , Y10S530/815 , Y10S530/816
摘要： A method is provided for preparing an active slide, including introducing a monomer containing an aldehyde group, or a mixture of a monomer containing an aldehyde group and an acidic functional group provider into a plasma chamber; and depositing the aldehyde group and acidic functional group onto the surface of an organic or inorganic matrix using plasma deposition to form a slide comprising a layer of polymerized actively functional groups thereon. The aldehyde groups and negatively charged groups are deposited on the surface of the active slide, such that the bio-molecules bound thereto possess the properties of an inducible orientation and thus form a mono-layer.
摘要翻译：提供了制备活性载体的方法，包括将含有醛基的单体或含有醛基的单体和酸性官能团提供剂的混合物引入等离子体室中; 以及使用等离子体沉积法将醛基和酸性官能团沉积在有机或无机基体的表面上以形成包含其上聚合的主动官能团层的载玻片。醛基和带负电荷的基团沉积在活性载体的表面上，使得与其结合的生物分子具有可诱导取向的特性，从而形成单层。

4. 发明授权

US06403368B1 On-spot hydrophilic enhanced slide and preparation thereof 有权
标题翻译：现场亲水增强滑片及其制备
公开(公告)号：US06403368B1
公开(公告)日：2002-06-11
申请号：US09695254
申请日：2000-10-25
申请人： Bor-Iuan Jan , Jia-Huey Tsao , Chih-Wei Ho , Chao-Chi Pan , Zu-Sho Chow , Yao-Sung Chang , Cheng-Tao Wu , Wen-Hsun Kuo
发明人： Bor-Iuan Jan , Jia-Huey Tsao , Chih-Wei Ho , Chao-Chi Pan , Zu-Sho Chow , Yao-Sung Chang , Cheng-Tao Wu , Wen-Hsun Kuo
IPC分类号： C12M134
CPC分类号： B82Y30/00 , B01J2219/00387 , B01J2219/00527 , B01J2219/00576 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00619 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , C40B40/06 , C40B40/10 , C40B60/14 , G01N33/545 , G02B21/34 , Y10T436/143333
摘要： The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.
摘要翻译：本发明公开了一种现场亲水增强载玻片/微阵列。该制备方法涉及通过共混，接枝或共聚疏水材料和带有官能团的化合物如酸酐，酰亚胺，环状酰胺和环状酯制备的疏水性共聚物，以及将疏水性共聚物应用于有机或无机底物。所得到的载片具有现场亲水/疏水动态转化的性质，以及用于制备高密度和高效率生物芯片/微阵列的现场亲水增强。

5. 发明授权

US07270636B2 Apparatus and method for pulse detection 有权
标题翻译：脉冲检测装置及方法
公开(公告)号：US07270636B2
公开(公告)日：2007-09-18
申请号：US11163881
申请日：2005-11-02
申请人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen
发明人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen
IPC分类号： A61B5/02
CPC分类号： A61B5/02007 , A61B5/0225 , A61B5/025 , A61B5/4854
摘要： An apparatus and method for pulse detection based on blood pressure measuring stage is disclosed. Both monitoring of blood pressure and blood vessel pulse are integrated and applied to an apparatus. With the components of the blood pressure monitor, such as an inflatable cuff an air pump and a variable flow valve, with a unique sequential pressure control of reduction and regulation of pressure, not only can blood pressure parameters but also pulse signals under various pressures be measured to provide a complete analysis of blood artery/vessel conditions.
摘要翻译：公开了一种基于血压测量级的脉冲检测装置和方法。将血压和血管脉搏的监测都集成并应用于装置。利用血压监测器的组件，例如可充气套管，气泵和可变流量阀，具有减少和调节压力的独特的连续压力控制，不仅血压参数而且在各种压力下的脉搏信号都是测量以提供血液动脉/血管状况的完整分析。

6. 发明申请

US20070038135A1 Portable physiological parameter detection/display assembly 审中-公开
标题翻译：便携式生理参数检测/显示组件
公开(公告)号：US20070038135A1
公开(公告)日：2007-02-15
申请号：US11438410
申请日：2006-05-22
申请人： Kang-Ping Lin , Bor-Iuan Jan , Hao-Yu Jan , Geng-Hong Lin
发明人： Kang-Ping Lin , Bor-Iuan Jan , Hao-Yu Jan , Geng-Hong Lin
IPC分类号： A61B5/02
CPC分类号： A61B5/02438 , A61B5/02405 , A61B5/02416 , A61B5/7445 , A61B2560/0418
摘要： A portable bio parameter detection/display assembly includes an optical sensor for engagement with an operator to acquire a pulse signal, an A/D converter converting the pulse signal into a digital format, a microprocessor for receiving the digital format pulse signal and proceeding with calculation of a pulse rate and at least one heart rate variability parameter, a display to display and a power module to provide necessary electricity to the assembly.
摘要翻译：便携式生物参数检测/显示组件包括用于与操作者接合以获取脉冲信号的光学传感器，将脉冲信号转换成数字格式的A / D转换器，用于接收数字格式脉冲信号并进行计算的微处理器脉搏率和至少一个心率变异性参数，显示器和功率模块，以向组件提供必要的电力。

7. 发明申请

US20060287605A1 HEART RATE VARIABILITY ANALYZING DEVICE 审中-公开
标题翻译：心率变异分析装置
公开(公告)号：US20060287605A1
公开(公告)日：2006-12-21
申请号：US11160281
申请日：2005-06-16
申请人： Kang-Ping Lin , Geng-Hong Lin , Bor-Iuan Jan
发明人： Kang-Ping Lin , Geng-Hong Lin , Bor-Iuan Jan
IPC分类号： A61B5/04
CPC分类号： A61B5/02405 , A61B5/04017 , A61B5/4035
摘要： The invention discloses an heart rate variability (HRV) analyzing device, which integrates the ECG signal measuring and processing technology and combines the HRV analyzing functions. The device adopts sensing electrodes disposed thereon or external sensing electrodes to record a subject's ECG signals. After being amplified, filtered and analog-to-digital converted, the ECG signals are transmitted to a built-in CPU to proceed with time domain and frequency domain analysis, and the results of the analysis are shown on a display unit. In such a way, the signal acquisition, algorithm calculation and display can be completed in the single device of the invention, which simplifies the conventional instruments and equipment, and provides an indication of the subject's health state in the aspect of self-health care.
摘要翻译：本发明公开了一种心率变异性（HRV）分析装置，其集成了ECG信号测量和处理技术，并结合HRV分析功能。该装置采用设置在其上的感测电极或外部感测电极来记录被检者的ECG信号。经过放大，滤波和模数转换后，将ECG信号传输到内置CPU进行时域和频域分析，分析结果显示在显示单元上。以这种方式，可以在本发明的单个装置中完成信号采集，算法计算和显示，这简化了传统的仪器和设备，并且在自我保健方面提供了受试者的健康状况的指示。

8. 发明申请

US20060264771A1 APPARATUS FOR EVALUATING CARDIOVASCULAR FUNCTIONS 审中-公开
标题翻译：评估心血管功能的装置
公开(公告)号：US20060264771A1
公开(公告)日：2006-11-23
申请号：US11306723
申请日：2006-01-09
申请人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen , Chih-Hsiung Yu
发明人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen , Chih-Hsiung Yu
IPC分类号： A61B5/04 , A61B5/02
CPC分类号： A61B5/0205 , A61B5/022 , A61B5/0245 , A61B5/0402
摘要： An apparatus is provided for evaluating cardiovascular functions. The apparatus combines the principles of measuring pressure and pulse signals, and monitors blood pressure, pulse wave velocity and electrocardiogram (ECG) signals simultaneously. An inflatable cuff measures blood pressure and pulse wave velocity. The apparatus also calculates systolic pressure, diastolic pressure, mean arterial pressure and other parameters related to blood pressure. The apparatus not only calculates vascular Stiffness Index (SI), vascular Reflection Index (RI) and other arterial related parameters but also Pulse Wave Velocity (PWV), heartbeat, QRS interval, ST segment, and other ECG parameters.
摘要翻译：提供了一种用于评估心血管功能的装置。该装置结合了测量压力和脉冲信号的原理，同时监测血压，脉搏波速度和心电图（ECG）信号。充气袖口测量血压和脉搏波速度。该装置还计算与血压相关的收缩压，舒张压，平均动脉压和其他参数。该装置不仅计算血管僵硬指数（SI），血管反射指数（RI）和其他动脉相关参数，而且还计算脉搏波速度（PWV），心跳，QRS间期，ST段和其他ECG参数。

9. 发明申请

US20060229517A1 APPARATUS AND METHOD FOR PULSE DETECTION 有权
标题翻译：用于脉冲检测的装置和方法
公开(公告)号：US20060229517A1
公开(公告)日：2006-10-12
申请号：US11163881
申请日：2005-11-02
申请人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen
发明人： Kang-Ping Lin , Hong-Dun Lin , Bor-Iuan Jan , Mei-Feng Chen
IPC分类号： A61B5/02
CPC分类号： A61B5/02007 , A61B5/0225 , A61B5/025 , A61B5/4854
摘要： An apparatus and method for pulse detection based on blood pressure measuring stage is disclosed. Both monitoring of blood pressure and blood vessel pulse are integrated and applied to an apparatus. With the components of the blood pressure monitor, such an inflatable cuff, an air pump and a variable flow valve, with a unique sequential pressure control of reduction and regulation of pressure, not only can blood pressure parameters but also pulse signals under various pressures be measured to provide a complete analysis of blood artery/vessel conditions.
摘要翻译：公开了一种基于血压测量级的脉冲检测装置和方法。将血压和血管脉搏的监测都集成并应用于装置。通过血压监测器的组件，这样一个可充气的袖带，一个气泵和一个可变流量阀，具有独特的顺序压力控制来减少和调节压力，不仅血压参数而且各种压力下的脉搏信号都是测量以提供血液动脉/血管状况的完整分析。

10. 发明授权

US06974529B2 Hand-held electrophoresis detection device and support thereof 有权
标题翻译：手持式电泳检测装置及其支架
公开(公告)号：US06974529B2
公开(公告)日：2005-12-13
申请号：US10316017
申请日：2002-12-11
申请人： Chung-Fan Chiou , Chih-Wei Ho , Bor-Iuan Jan , Jian Je Jian , Chien-Tsung Wu , Hsi-Hsin Shih
发明人： Chung-Fan Chiou , Chih-Wei Ho , Bor-Iuan Jan , Jian Je Jian , Chien-Tsung Wu , Hsi-Hsin Shih
IPC分类号： G01N27/447 , G01N27/453 , B01D85/00
CPC分类号： G01N27/44704
摘要： A hand-held electrophoresis detection device and support thereof. The hand-held electrophoresis detection device includes a support and a cartridge. The cartridge attaches a sample, and is disposed in the support in a detachable manner.
摘要翻译：一种手持式电泳检测装置及其支撑体。手持式电泳检测装置包括支架和盒。该盒附接样品，并以可拆卸的方式设置在支撑件中。

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