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1. 发明授权

US07351744B2 Naphthalene derivatives as termite repellents and toxicants 有权
标题翻译：萘衍生物作为白蚁驱避剂和有毒物质
公开(公告)号：US07351744B2
公开(公告)日：2008-04-01
申请号：US10641315
申请日：2003-08-14
申请人： Gregg Henderson , Sanaa A. Ibrahim , Rosemary Patton , Roger A. Laine , Betty C. R. Zhu , Feng Chen
发明人： Gregg Henderson , Sanaa A. Ibrahim , Rosemary Patton , Roger A. Laine , Betty C. R. Zhu , Feng Chen
IPC分类号： A01N35/00
CPC分类号： A01N31/04 , A01N27/00 , A01N31/14 , A01N35/04 , Y10S424/11
摘要： Several derivatives of naphthalene, including 1′-acetonaphthone, 2′-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of termites, and resulted in significant reduction in termite feeding activity. For example, 2′-acetonaphthone was found to be an effective repellent and feeding deterrent of termites. Termites exposed to concentrations as low as 8 mg/kg sand exhibited a significant reduction in tunneling and feeding activity. Moreover, some of the dead termites had symptoms indicative of a failure to molt. At concentrations ≧20 μg/cm2, 2′-acetonaphthone was a strong repellent. Interestingly, at 160-fold lower concentration (0.125 μg/cm2), 2′-acetonaphthone stimulated termite feeding activity. As a sand barrier, 2′-acetonaphthone significantly inhibited tunneling and feeding activity in concentrations from 8.33 to 35.0 mg/kg. Molting problems were also identified in termites exposed to 2′-acetonaphthone.
摘要翻译：发现了萘的几种衍生物，包括1'-乙酰萘酮，2'-乙酸萘，1-甲氧基萘和2-甲氧基萘，是白蚁的有效毒素和驱避剂，导致白蚁进食活动显着降低。例如，发现2'-乙酰萘酮是有效的驱避剂和抑制白蚁的威慑。暴露于浓度低至8 mg / kg沙粒的白蚁显示隧道和进食活动的显着减少。此外，一些死亡的白蚁有表现为蜕皮失败的症状。在浓度≥20mug/ cm 2的情况下，2'-乙酰萘酮是强驱虫剂。有趣的是，在浓度为160倍（0.125mug / cm 2））的情况下，2'-乙酰萘酮刺激白蚁进食活性。作为沙屏障，2'-乙酰萘酮显着抑制了浓度为8.33〜35.0mg / kg的隧道和摄食活性。在暴露于2'-乙酰四氢萘酮的白蚁中也发现了溶解问题。

2. 发明授权

US06890960B1 Vetiver oil extracts as termite repellent and toxicant 有权
标题翻译：香根草油提取物为白蚁驱避剂和毒物
公开(公告)号：US06890960B1
公开(公告)日：2005-05-10
申请号：US09856760
申请日：2000-10-18
申请人： Gregg Henderson , Roger A. Laine , Donald O. Heumann , Feng Chen , Betty C. R. Zhu
发明人： Gregg Henderson , Roger A. Laine , Donald O. Heumann , Feng Chen , Betty C. R. Zhu
IPC分类号： A01N31/00 , A01N31/06 , A01N35/00 , A01N35/06
CPC分类号： A01N31/06 , A01N35/06 , A01N27/00 , A01N25/08 , A01N2300/00
摘要： Extracts of vetiver oil were found to significantly repel termites. In one extract, nootkatone was isolated and found to be a significant repellent and toxicant of termites. Nootkatone significantly decreased food consumption, decreased tunneling behavior, and increased mortality in termites. Nootkatone is an effective repellent and toxicant of termites either by itself or as an addition to other materials or substrates, including mulches made from vetiver grass roots or other wood products. Nootkatone can also be used to protect construction wood from attack by Formosan subterranean termites. Nootkatone as a repellent is non-toxic to humans and other mammals and is environmentally safe. In addition, α-cedrene was found to be a weak termite repellent; and both zizanol and bicyclovetivenol were found to be repellents and toxicants of termites.
摘要翻译：发现香根草油的提取物显着排斥白蚁。在一种提取物中，分离出诺塔卡酮，发现它是一种重要的驱避剂和有毒的白蚁。 Nootkatone显着降低了食物消耗，降低了隧道行为，并增加了白蚁死亡率。 Nootkatone是一种有效的驱虫剂和有毒物质的白蚁，其本身或作为其他材料或底物的添加剂，包括由香根草草根或其他木制品制成的覆盖物。 Nootkatone也可用于保护建筑木材免受台山地下白蚁的攻击。 Nootkatone作为驱避剂对人类和其他哺乳动物无毒，对环境无害。此外，发现α-雪松是一种弱白蚁驱虫剂; 发现齐赞醇和双环己酮醇都是白蚁的驱避剂和毒物。

3. 发明授权

US06906108B2 Extracts of vetiver oil as repellent and toxicant to ants, ticks, and cockroaches 有权
标题翻译：香根草油的提取物作为驱避剂，对蚂蚁，蜱和蟑螂有毒
公开(公告)号：US06906108B2
公开(公告)日：2005-06-14
申请号：US09932555
申请日：2001-08-17
申请人： Gregg Henderson , Donald O. Heumann , Roger A. Laine , Lara Maistrello , Betty C. R. Zhu , Feng Chen
发明人： Gregg Henderson , Donald O. Heumann , Roger A. Laine , Lara Maistrello , Betty C. R. Zhu , Feng Chen
IPC分类号： A01N31/04 , A01N35/06 , A01N45/02 , A01N65/00 , A61K31/12 , A61K31/045 , A61K31/015 , A01N27/00
CPC分类号： A01N31/04 , A01N35/06 , A01N45/02 , A01N65/06 , A01N65/44 , Y02A50/322
摘要： Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in fire ants. Nootkatone is an effective repellent and toxicant of ants either by itself or as an addition to other substrates, including mulches made from vetiver grass roots, diatomaceous earth, alumina, silica, clays; building materials made from either aluminum or wood; and other suitable solid substances. Nootkatone was also a repellent and toxicant to ticks; and a repellent to cockroaches. Nootkatone is non-toxic to humans and other mammals and is environmentally safe. In addition, it is believed that other extracts of vetiver oil, specifically α-cedrene, zizanol and bicyclovetivenol, will be effective against ants, ticks, and cockroaches.
摘要翻译：发现香根草油的提取物是蚂蚁，蜱和蟑螂的驱虫剂和有毒物质。 Nootkatone被证明可以显着降低蚂蚁入侵并增加蚂蚁的死亡率。 Nootkatone是本身或作为其他底物的补充剂，包括由香根草草根，硅藻土，氧化铝，二氧化硅，粘土制成的覆盖物的有效驱避剂和毒物; 铝或木制建筑材料; 和其他合适的固体物质。 Nootkatone也是蜱虫的驱避剂和毒物; 和驱虫剂蟑螂。 Nootkatone对人类和其他哺乳动物无毒，对环境无害。此外，据信香根草油的其他提取物，特别是α-雪松烯，齐赞醇和双环己酮醇，对蚂蚁，蜱和蟑螂有效。

4. 发明授权

US06897244B2 Dihydronootkatone and tetrahydronootkatone as repellents to arthropods 有权
公开(公告)号：US06897244B2
公开(公告)日：2005-05-24
申请号：US10189631
申请日：2002-07-03
申请人： Betty C. R. Zhu , Gregg Henderson , Roger A. Laine
发明人： Betty C. R. Zhu , Gregg Henderson , Roger A. Laine
IPC分类号： A01N35/06 , A01N35/04
CPC分类号： A01N35/06 , Y10S424/10 , Y10S514/919
摘要： Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone were shown to effectively repel termites at concentrations as low as 2 μg/ml and 12.5 μg/ml, respectively. Tetrahydronootkatone was shown to repel mosquitos at a concentration of 5%. Tetrahydronootkatone is an effective repellent of termites either by itself or as an addition to other substrates, including mulches made from wood products or other cellulose-containing material. Tetrahydronootkatone or 1,10-dihydronootkatone can be used to protect construction wood from attack by Formosan subterranean termites, either alone or used in combination with other compounds known to repel termites. It is also believed that these compounds will prove effective in repelling ants, ticks, and cockroaches. These derivatives of nootkatone are non-toxic to humans and other mammals and environmentally safe.

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