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1. 发明授权

US08383043B2 Analyzer system 有权
标题翻译：分析仪系统
公开(公告)号：US08383043B2
公开(公告)日：2013-02-26
申请号：US11615884
申请日：2006-12-22
申请人： Aravind Padmanabhan , James A. Cox , Bernard S. Fritz , Tom M. Rezachek , Peter L. Reutiman , Ron L. Bardell , Cleopatra Cabuz
发明人： Aravind Padmanabhan , James A. Cox , Bernard S. Fritz , Tom M. Rezachek , Peter L. Reutiman , Ron L. Bardell , Cleopatra Cabuz
IPC分类号： G01N33/00 , G01N33/48
CPC分类号： G01N35/00603 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L9/527 , B01L2200/027 , B01L2200/04 , B01L2200/0636 , B01L2200/0684 , B01L2200/143 , B01L2200/146 , B01L2300/021 , B01L2300/044 , B01L2300/0627 , B01L2300/0672 , B01L2300/0816 , B01L2300/0877 , B01L2300/14 , B01L2400/0406 , B01L2400/0481 , B01L2400/0487 , G01N15/1404 , G01N15/1459 , G01N15/1484 , G01N21/53 , G01N29/032 , G01N33/5094 , G01N35/00663 , G01N2015/0069 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1452 , G01N2015/1486 , G01N2035/00148 , G01N2035/00158 , G01N2035/00247 , G01N2035/1034 , G01N2035/1053 , G01N2291/02433 , G01N2291/02836 , G01N2291/02872
摘要： A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduce risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.
摘要翻译：与样品分析仪相关的系统，更具体地，涉及操作简单且降低向用户提供错误结果的风险的样品分析仪。在一些情况下，样品分析仪可以是便携式样品分析仪，其包括一次性流体盒。不需要对分析仪的操作员进行培训。

2. 发明申请

US20120199743A1 TERAHERTZ DISPERSIVE SPECTROMETER SYSTEM 有权
标题翻译： TERAHERTZ分散光谱仪系统
公开(公告)号：US20120199743A1
公开(公告)日：2012-08-09
申请号：US13367209
申请日：2012-02-06
申请人： James A. Cox , Bernard S. Fritz , Fouad Nusseibeh
发明人： James A. Cox , Bernard S. Fritz , Fouad Nusseibeh
IPC分类号： G01J3/42 , G01J3/443
CPC分类号： G01J3/42 , G01J5/0837 , G01N21/3563 , G01N21/3577 , G01N21/3581
摘要： A spectrometer system for providing information about a target with terahertz radiation. The system may receive incident radiation from the target through fore optics, a slit aperture, secondary optics and a dispersive element which images a slit on an array of terahertz sensitive detectors. The detectors may include uncooled sensors. Each sensor may be connected to its own micro antenna. The array of detectors may be situated proximate to the dispersive element so that radiation from the element may be dispersed according to wavelength to the respective detectors optimally sensitive to the various respective wavelengths. Detector signals indicating the impingement of terahertz radiation may provide information for identifying a material of the target.
摘要翻译：用于提供有关太赫兹辐射的目标信息的光谱仪系统。该系统可以通过前光学器件，狭缝孔，次光学器件和对在太赫兹敏感探测器阵列上的狭缝进行成像的色散元件来接收来自靶的入射辐射。检测器可以包括非制冷传感器。每个传感器可以连接到其自己的微天线。检测器阵列可以位于分散元件附近，使得来自元件的辐射可以根据波长分散到对各种相应波长最佳敏感的各个检测器。指示太赫兹辐射冲击的检测器信号可以提供用于识别目标材料的信息。

3. 发明授权

US08059344B2 Multi-band lens 有权
标题翻译：多频段镜头
公开(公告)号：US08059344B2
公开(公告)日：2011-11-15
申请号：US11160048
申请日：2005-06-07
申请人： Roland A. Wood , Bernard S. Fritz
发明人： Roland A. Wood , Bernard S. Fritz
IPC分类号： G02B13/00
CPC分类号： G02B13/146
摘要： An optical lens system that focuses both a first band of wavelengths and a second band of wavelengths onto a common focal plane. In some cases, the lens system includes a first region for focusing a first band of wavelengths onto a focal plane, and a second region for focusing a second band of wavelengths onto the same focal plane. Depending on the wavelengths and materials involved, the first region may or may not focus the second band of wavelengths onto the focal plane, and in some cases, may or may not even transmit the second band of wavelengths to the focal plane. Likewise, the second region may or may not focus the first band of wavelengths onto the focal plane, and in some cases, may or may not even transmit the first band of wavelengths onto the focal plane, but this is not required. In some embodiments, an additional lens may be provided between the lens system and the common focal plane to help focus the first band of wavelengths and the second band of wavelengths onto the common focal plane. The additional lens may be made from a material or material system that transmits and focuses both the first band of wavelengths and the second band of wavelengths.
摘要翻译：一种将第一波长波段和第二波长带聚焦到公共焦平面上的光学透镜系统。在一些情况下，透镜系统包括用于将第一波长带聚焦到焦平面上的第一区域和用于将第二波长带聚焦到同一焦平面上的第二区域。取决于所涉及的波长和材料，第一区域可以或可以不将第二波长带聚焦到焦平面上，并且在一些情况下，可能甚至不会将第二波长带透射到焦平面。类似地，第二区域可以或可以不将第一波长带聚焦到焦平面上，并且在一些情况下，可能甚至不会将第一波长带传播到焦平面上，但是这不是必需的。在一些实施例中，可以在透镜系统和公共焦平面之间提供附加透镜，以帮助将第一波长波段和第二波长带聚焦到公共焦平面上。附加透镜可以由材料或材料系统制成，该材料或材料系统透射和聚焦第一波长波段和第二波长波段。

4. 发明授权

US07895880B2 Photoacoustic cell incorporating a quantum dot substrate 有权
标题翻译：结合量子点基片的光声单元
公开(公告)号：US07895880B2
公开(公告)日：2011-03-01
申请号：US12105241
申请日：2008-04-17
申请人： Bernard S. Fritz , Matthew S. Marcus
发明人： Bernard S. Fritz , Matthew S. Marcus
IPC分类号： G01N21/61 , G01N29/02
CPC分类号： G01N21/1702 , B82Y20/00 , G01N2021/1704
摘要： Embodiments of the apparatus, systems, and methods relate to a photoacoustic cell including an excitation source, a chamber, and a quantum dot substrate between the excitation source and the chamber. The excitation source generates a light spectrum. The quantum dot substrate, when subjected to the light spectrum, emits a specific wavelength of light to be received by the chamber. The photoacoustic cell apparatus may be part of a portable gas sensing system, and may be used to detect and measure the concentration of one or more gases. Additional apparatus, systems, and methods are disclosed.
摘要翻译：装置，系统和方法的实施例涉及在激发源和腔室之间包括激发源，腔室和量子点衬底的光声单元。激发源产生光谱。当经受光谱时，量子点衬底发射由腔室接收的特定波长的光。光电池装置可以是便携式气体传感系统的一部分，并且可以用于检测和测量一种或多种气体的浓度。公开了附加装置，系统和方法。

5. 发明授权

US07485153B2 Fluid free interface for a fluidic analyzer 有权
标题翻译：流体分析仪的无流体界面
公开(公告)号：US07485153B2
公开(公告)日：2009-02-03
申请号：US11306401
申请日：2005-12-27
申请人： Aravind Padmanabhan , Tom Rezachek , Ron L. Bardell , Douglas Bird , Bernard S. Fritz
发明人： Aravind Padmanabhan , Tom Rezachek , Ron L. Bardell , Douglas Bird , Bernard S. Fritz
IPC分类号： G01D21/00
CPC分类号： B01L9/527 , B01L3/502715 , B01L3/502746 , B01L2200/027 , B01L2300/0809 , B01L2300/0877 , B01L2300/123 , B01L2400/0481 , F04C2/18 , F04C13/001 , G01N33/18 , G01N2035/00158
摘要： Instrument-cartridge interfaces for fluidic analyzers that have an instrument and a removable cartridge are disclosed. For example, and in one illustrative embodiment, the instrument may include a needle that is adapted to penetrate a septum on a removable cartridge. In another illustrative embodiment, the instrument may include a plunger that is adapted to deform a deformable membrane on a removable cartridge. In yet another illustrative embodiment, the instrument may include a nozzle that is adapted to mate and seal with a flow channel on a removable cartridge. Techniques for detecting the flow rate in a flow channel on a removable cartridge, as well as the position of fluid in a flow channel of a removable cartridge, are also disclosed.
摘要翻译：公开了具有仪器和可移除盒的流体分析仪的盒式磁带接口。例如，在一个说明性实施例中，仪器可以包括适于穿透可移除盒的隔膜的针。在另一说明性实施例中，仪器可以包括适于使可移除盒上的可变形膜变形的柱塞。在另一个说明性实施例中，仪器可以包括适于与可移除盒上的流动通道配合和密封的喷嘴。还公开了用于检测可移除盒上的流动通道中的流速以及可移除盒的流动通道中的流体位置的技术。

6. 发明授权

US07333197B2 Raman detection based flow cytometer 有权
标题翻译：基于拉曼检测的流式细胞仪
公开(公告)号：US07333197B2
公开(公告)日：2008-02-19
申请号：US10991001
申请日：2004-11-17
申请人： Bernard S. Fritz , Aravind Padmanabhan , Cleopatra Cabuz
发明人： Bernard S. Fritz , Aravind Padmanabhan , Cleopatra Cabuz
IPC分类号： G01N21/00
CPC分类号： G01N21/658 , G01N15/147
摘要： A method and apparatus for enabling chemical identification of individual particles, cells of molecules by obtaining a Raman spectrum of a particle, cell or molecule as it flows past a sensing point in a flow cytometer. The particles, which may be cells or molecules, are associated with a suitable noble metal colloid or colloidal aggregate. Cellular particles may be associated with gold or silver colloidal particles by ultra-sonic sonification while in a sample preparation reservoir containing the gold or silver colloidal suspension. The colloid associated particles are then hydrodynamically focused into a single file by a fluid control module. The surface-enhance Raman Spectrum of individual particles are obtained by illuminating the particle with a laser as the particle flows past a sensing point and gathering the light that is non-elastically scattered (Raman scattered) by the particle. The surface-enhanced Raman spectrum is then analyzed to identify the particle.
摘要翻译：一种方法和装置，用于通过在流式细胞计数器中流过感测点时获得粒子，细胞或分子的拉曼光谱，从而能够化学鉴定单个颗粒，分子细胞。可以是细胞或分子的颗粒与合适的贵金属胶体或胶体聚集体相关联。在含有金或银胶体悬浮液的样品制备储存器中，细胞颗粒可以通过超声波超声处理与金或银胶体颗粒结合。然后通过流体控制模块将胶体相关颗粒流体动力聚焦成单个文件。当颗粒流过感测点并通过颗粒收集非弹性散射（拉曼散射）的光时，通过用激光照射颗粒来获得单个颗粒的表面增强拉曼光谱。然后分析表面增强拉曼光谱以鉴定颗粒。

7. 发明授权

US07242474B2 Cytometer having fluid core stream position control 有权
标题翻译：血细胞计数器具有流体核心流位置控制
公开(公告)号：US07242474B2
公开(公告)日：2007-07-10
申请号：US10899607
申请日：2004-07-27
申请人： James A. Cox , Bernard S. Fritz
发明人： James A. Cox , Bernard S. Fritz
IPC分类号： G01N21/00
CPC分类号： G01N15/1404 , Y10T436/118339
摘要： A cytometer having two or more chambers or regions in a containment structure of sheathing fluid that may be used to provide hydrodynamic focusing of another fluid having particles to be observed. The latter fluid may be a core stream which may have its lateral position in a flow or measurement channel affected by control of at least one of the parameters of the several segments of the sheathing fluid. The lateral position of the core stream may be aligned with a light source and detector for a count and observation of the particles. Electrical signals from the detector may be fed back to a processor which may control one or more parameters of the sheathing fluid in the various chambers or regions via pumps, valves, and flow and pressure sensors. This control of parameters may provide for the positioning of the core stream. This cytometer may be miniaturized.
摘要翻译：具有在护套液体的容纳结构中的两个或更多个腔室或区域的细胞计数器，其可用于提供具有待观察颗粒的另一种流体的流体动力聚焦。后一流体可以是芯流，其可以在流动或测量通道中具有其横向位置，该流动或测量通道受到护套流体的几个段的参数中的至少一个参数的控制的影响。核心流的横向位置可以与光源和检测器对准，用于计数和观察颗粒。来自检测器的电信号可以被反馈到处理器，处理器可以通过泵，阀和流量和压力传感器来控制各个室或区域中的护套流体的一个或多个参数。参数的这种控制可以提供核心流的定位。该细胞仪可以小型化。

8. 发明授权

US06844537B2 Method and device for measuring the velocity of a moving surface 有权
标题翻译：测量移动表面速度的方法和装置
公开(公告)号：US06844537B2
公开(公告)日：2005-01-18
申请号：US10037012
申请日：2001-12-31
申请人： Mark L. Wilson , Bernard S. Fritz
发明人： Mark L. Wilson , Bernard S. Fritz
IPC分类号： G01P3/36 , G01S17/58 , G01S17/89 , G01C21/02
CPC分类号： G01S17/58 , G01P3/36 , G01S17/89
摘要： The invention includes a device for measuring the velocity of a target that includes an array of vertical cavity surface emitting lasers having an energy output, a first lens configured to capture the energy output of the array and project it onto the target whose velocity is to be monitored, a second lens configured to capture the energy output reflected from the target, and at least one detector configured to detect the energy transmitted from the second lens, where the energy of the array projected onto the target creates pulses of light from reflectance off of surface imperfections on the target, and the velocity of the target is determined by monitoring the frequency of the pulses of light. The invention also includes a method of measuring the velocity of a target that includes projecting an image of at least one vertical cavity surface emitting laser array onto the target, monitoring the intensity pattern formed from the image reflecting off of the target with at least one light intensity detector to produce an analog signal, converting the analog signal to a digital signal having the same frequency, measuring the frequency of the digital signal with a counter, and processing the frequency with a microprocessor to determine the velocity of the target.
摘要翻译：本发明包括用于测量目标的速度的装置，该装置包括具有能量输出的垂直腔表面发射激光器的阵列，第一透镜被配置为捕获阵列的能量输出并将其投射到其速度为的目标上被配置为捕获从目标反射的能量输出的第二透镜以及被配置为检测从第二透镜发射的能量的至少一个检测器，其中投射到目标上的阵列的能量产生来自反射率的光的脉冲通过监视光脉冲的频率来确定目标上的表面缺陷，目标的速度。本发明还包括一种测量目标的速度的方法，该方法包括将至少一个垂直腔表面发射激光阵列的图像投射到目标上，用至少一个光监测从反射离开靶的图像形成的强度图案强度检测器产生模拟信号，将模拟信号转换成具有相同频率的数字信号，用计数器测量数字信号的频率，并用微处理器处理频率以确定目标的速度。

9. 发明授权

US06829370B1 Near-IR human detector 有权
标题翻译：近红外人体检测器
公开(公告)号：US06829370B1
公开(公告)日：2004-12-07
申请号：US09723902
申请日：2000-11-28
申请人： Ioannis Pavlidis , Peter F. Symosek , Bernard S. Fritz
发明人： Ioannis Pavlidis , Peter F. Symosek , Bernard S. Fritz
IPC分类号： G06K900
CPC分类号： G06K9/2018 , G06K9/00228 , G06K9/00362
摘要： A detection method and system that detects reflection from a scene in at least a portion of an upper band of the near infrared spectrum (e.g., at least a portion within the range of 1.4 &mgr;m and above in the near infrared spectrum). The presence of a human body in the scene is then determined by comparing the reflection of at least one region of the scene (e.g., at least one region of the scene including a face region of the human body) to at least one other region of the scene (e.g., at least another region of the scene including one or more inanimate objects).
摘要翻译：一种检测方法和系统，其检测近红外光谱的上段的至少一部分中的场景的反射（例如，近红外光谱中的至少一部分在1.4mum以上的范围内）。然后通过将场景的至少一个区域（例如，包括人体的脸部区域的场景的至少一个区域）的反射与至少一个区域的反射来确定人体在场景中的存在，场景（例如，场景的至少另一区域，包括一个或多个无生命物体）。

10. 发明授权

US06556349B2 Variable focal length micro lens array field curvature corrector 有权
标题翻译：可变焦距微透镜阵列场曲率校正器
公开(公告)号：US06556349B2
公开(公告)日：2003-04-29
申请号：US09749296
申请日：2000-12-27
申请人： James Allen Cox , Bernard S. Fritz
发明人： James Allen Cox , Bernard S. Fritz
IPC分类号： G02B2710
CPC分类号： H01L27/14627 , G02B6/12002 , G02B6/138 , G02B6/4201 , G02B6/4206 , G02B6/4214 , G02B6/4249 , G02B7/04 , H01L31/02325 , H01L31/02327
摘要： The present invention provides an optical system that includes an array of opto-electronic devices, an array of micro lenses, and a fore optic. The array of opto-electronic devices lie substantially along a plane, but the fore optic has a non-planar focal field. To compensate for the non-planar focal field of the fore optic, each opto-electronic device has a corresponding micro lens. Each micro lens has a focal length and/or separation distance that compensates for the non-planar focal field of the fore optic. As a result, light that is provided by the fore optic is reconfigured by the micro lenses to be substantially focused along the plane of the array of opto-electronic devices.
摘要翻译：本发明提供了一种光学系统，其包括光电子器件阵列，微透镜阵列和前视镜。光电子器件的阵列基本上沿着平面放置，但前视镜具有非平面焦点。为了补偿前视镜的非平面焦点，每个光电器件具有相应的微透镜。每个微透镜具有补偿前视镜的非平面焦点的焦距和/或间隔距离。结果，由前光学器件提供的光被微透镜重新配置成沿着光电子器件阵列的平面基本聚焦。

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