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1. 发明授权

US08471054B2 Resorbable phenolic polymers 有权
公开(公告)号：US08471054B2
公开(公告)日：2013-06-25
申请号：US13414090
申请日：2012-03-07
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
IPC分类号： C07C69/00 , C08G65/38
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.

2. 发明申请

US20060036303A1 Intravascular systems for corporeal cooling 审中-公开
公开(公告)号：US20060036303A1
公开(公告)日：2006-02-16
申请号：US11251695
申请日：2005-10-17
申请人： Arthur Schwartz
发明人： Arthur Schwartz
IPC分类号： A61F7/00
CPC分类号： A61M25/1011 , A61M25/0662 , A61M2025/1052 , A61M2025/1059 , A61M2205/3606
摘要： A catheter for intravascular corporeal cooling comprises an elongated tubular member having at least one lumen extending therethrough for providing cooled blood, an inflatable annular balloon positioned on the outer surface of the elongated tubular member, and a pressure reliever positioned in the external wall of the elongated tubular member and proximal to the annular inflatable balloon, wherein when the pressure of blood within a lumen reaches a predetermined value, the pressure reliever opens to permit fluid to be released from the elongated tubular member. In other embodiments of the invention the catheter may have two or more inflatable annular balloons that are separately inflatable and/or the catheter has an insulative outer annular member.

3. 发明授权

US3242613A Toy submarine with ballast control therefor 失效
标题翻译：具有镇流器控制的玩具潜艇
公开(公告)号：US3242613A
公开(公告)日：1966-03-29
申请号：US48036265
申请日：1965-08-17
申请人： ARTHUR SCHWARTZ
发明人： ARTHUR SCHWARTZ
IPC分类号： A63H23/04
CPC分类号： A63H23/04

4. 发明授权

US08445603B2 Linear polyesteramides from aminophenolic esters 有权
公开(公告)号：US08445603B2
公开(公告)日：2013-05-21
申请号：US12564736
申请日：2009-09-22
申请人： Arthur Schwartz , Satish Pulapura , Sarita Nethula , Archana Rajaram , Arikha Moses
发明人： Arthur Schwartz , Satish Pulapura , Sarita Nethula , Archana Rajaram , Arikha Moses
IPC分类号： C08F283/04
CPC分类号： C08G69/44 , A61K9/0024 , A61K31/09 , A61K31/4465 , A61K31/496 , A61K31/65 , A61K31/7036 , A61K47/34 , A61L29/06 , A61L29/085 , A61L29/148 , A61L29/16 , A61L31/06 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/404 , A61L2300/802 , A61L2400/18 , A61L2420/06 , A61M2025/0057 , C08G69/00 , C08L77/12 , C08L101/00 , C08L2666/02 , C08L2666/20
摘要： The present invention is directed to linear, biodegradable polyesteramide (PEA) polymers synthesized with repeating units derived from aminophenol esters and diacids. These PEAs have a monomer repeat represented by as well as a variety of uses to coat, form or comprise medical devices, combination medical devices and pharmaceutical compositions, including sustained release formulations.

5. 发明申请

US20100167992A1 Phenyl Ester Side Chains to Increase Polymer Resorptivity 有权
标题翻译：苯酯侧链提高聚合物吸收性
公开(公告)号：US20100167992A1
公开(公告)日：2010-07-01
申请号：US12641996
申请日：2009-12-18
申请人： Arthur Schwartz , Satish Pulapura , Sarita Nethula
发明人： Arthur Schwartz , Satish Pulapura , Sarita Nethula
IPC分类号： A61K47/30 , A61K38/14 , A61K31/704 , A61K31/65 , A61K31/496 , A61K31/085 , A61K47/42 , A61K47/36 , C08G71/04 , C08G65/38 , C08G63/00 , C08G79/02 , C07C69/76 , A61P7/00 , A61P29/00 , A61P31/00 , A61P17/00
CPC分类号： A61L31/10 , A61L31/041 , A61L31/148 , C08G63/6856 , C08G64/12
摘要： The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
摘要翻译：本发明涉及改性以增加其可再吸收性的聚合物。特别地，本发明的聚合物具有优异的离去基团的苯基酯侧链，从而提高聚合物相对于相同聚合物的吸收速率，例如，带有相当量的烷基酯侧链。这样的聚合物通常是水不溶性的，但是当被修饰能够溶解药物并且在降解和再吸收时，以受控和/或持续的方式在生理环境中释放它们。

6. 发明申请

US20120165495A1 RESORBABLE PHENOLIC POLYMERS 有权
标题翻译：可分离的酚醛聚合物
公开(公告)号：US20120165495A1
公开(公告)日：2012-06-28
申请号：US13414090
申请日：2012-03-07
申请人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
发明人： Arikha Moses , Satish Pulapura , Arthur Schwartz , Qing Ge , Irene Shatova
IPC分类号： C08G63/193 , C07H15/18 , C07C69/716 , C07C235/52 , C07C237/52
CPC分类号： C08G69/48 , C07C235/34 , C07C235/52 , C08G63/6856 , C08G64/12 , C08G73/028
摘要： The invention provides biocompatible resorbable polymers, comprising monomer units having formula (I), formula (II), formula (III) or formula (IV). The polymers degrade over time when implanted in the body, and are useful as components of implantable medical devices.
摘要翻译：本发明提供具有式（I），式（II），式（III）或式（IV））的单体单元的生物相容性可再吸收聚合物。当植入体内时，聚合物随时间降解，并且可用作可植入医疗装置的组件。

7. 发明授权

US07271234B2 Polyarylates for drug delivery and tissue engineering 有权
标题翻译：用于药物递送和组织工程的聚芳酯
公开(公告)号：US07271234B2
公开(公告)日：2007-09-18
申请号：US10512609
申请日：2003-04-24
申请人： Joachim B. Kohn , Satish Pulapura , Arthur Schwartz , Raman Bahulekar
发明人： Joachim B. Kohn , Satish Pulapura , Arthur Schwartz , Raman Bahulekar
IPC分类号： C08G64/00
CPC分类号： A61K9/0024 , A61K9/146 , A61K9/1641 , A61L27/18 , A61L27/34 , A61L27/54 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/252 , A61L2300/256 , A61L2300/258 , A61L2300/80 , C08G63/672 , C08G63/6856 , Y10T428/31504 , C08L67/02
摘要： Biocompatible polyarylates of tyrosine-derived diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed.
摘要翻译：公开了酪氨酸衍生的二酚化合物和聚（环氧烷）二羧酸的生物相容性多芳基化合物，由其形成的制品和治疗用途。

8. 发明授权

US3994089A Coupon bearing label 失效
标题翻译：优惠券轴承标签
公开(公告)号：US3994089A
公开(公告)日：1976-11-30
申请号：US321249
申请日：1973-01-05
申请人： Arthur Schwartz
发明人： Arthur Schwartz
IPC分类号： G09F3/02 , G09F3/00
CPC分类号： G09F3/0289
摘要： A coupon bearing label includes a pair of coinciding similar panels joined along their bottom edges by a fold line and along their side borders by a suitable adhesive, and tongues project upwardly from the panels and are spot or line joined by a suitable adhesive. The back panel is cemented to a receptacle and the face panel has score lines or lines of weakening delineating a separable rectangular coupon, the bottom score line coinciding with the fold line. In an alternative construction, the back and face panels are joined along a pair of their side edges by a fold line and an intermediate panel is delineated from the opposite edge of the back panel by a fold line and is sandwiched between the face and back panel. The free side border of the face panel is separably joined to the underlying border of the intermediate border by adhesive. Separable rectangular coupons are delineated by score lines on both the face and intermediate panels. The panels carry any desired information.
摘要翻译：优惠券轴承标签包括一对重合的相似面板，它们的底部边缘通过折叠线并通过合适的粘合剂沿着它们的侧边缘连接，并且舌片从面板向上突出并且是通过合适的粘合剂连接的点或线。后面板胶合到容器，面板具有划分线或弱线的划线，描绘可分离的矩形优惠券，底部刻痕线与折叠线重合。在另一种结构中，后面板和面板通过折叠线沿其一对侧边缘连接，并且中间面板通过折叠线从后面板的相对边缘划定并夹在面板和后面板之间。面板的自由侧边界通过粘合剂可分离地连接到中间边框的下方边界。可分离的矩形优惠券由面板和中间面板上的刻痕线划定。面板携带任何所需的信息。

9. 发明授权

US08629233B2 Phenyl ester side chains to increase polymer resorptivity 有权
标题翻译：苯酯侧链增加聚合物吸收性
公开(公告)号：US08629233B2
公开(公告)日：2014-01-14
申请号：US12641996
申请日：2009-12-18
申请人： Arthur Schwartz , Satish Pulapura , Sarita Nethula
发明人： Arthur Schwartz , Satish Pulapura , Sarita Nethula
IPC分类号： C08G69/44
CPC分类号： A61L31/10 , A61L31/041 , A61L31/148 , C08G63/6856 , C08G64/12
摘要： The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solublize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.
摘要翻译：本发明涉及改性以增加其可再吸收性的聚合物。特别地，本发明的聚合物具有优异的离去基团的苯基酯侧链，从而提高聚合物相对于相同聚合物的吸收速率，例如，带有相当量的烷基酯侧链。这样的聚合物通常是水不溶性的，但是当被修饰能够溶解药物并且在降解和再吸收时，以受控和/或持续的方式在生理环境中释放它们。

10. 发明授权

US08200714B2 Apparatus, systems and methods for configurable defaults for XML data 有权
标题翻译：用于XML数据的可配置默认值的设备，系统和方法
公开(公告)号：US08200714B2
公开(公告)日：2012-06-12
申请号：US12463280
申请日：2009-05-08
申请人： Jack Arthur Schwartz
发明人： Jack Arthur Schwartz
IPC分类号： G06F17/30
CPC分类号： G06F17/2247
摘要： A data tree is generated in memory by parsing a first XML file. Default setting requests and validation requests are read from a second XML file. Default data values for nodes in the data tree are generated by executing default data generation code from locations specified in the default setting requests and recorded in the data tree. The content of data stored in nodes of the data tree is then validated by executing validation code from locations specified in the validation requests. The data tree is then searched by getting a nodepath, parsing the nodepath into a plurality of path pieces, searching the data tree based on each of the path pieces, and returning one or more nodes of the data tree based on the search that satisfy the path pieces. A data value of one or more nodes or child nodes may be specified to narrow the search.
摘要翻译：通过解析第一个XML文件在内存中生成数据树。从第二个XML文件读取默认设置请求和验证请求。通过从默认设置请求中指定的位置执行默认数据生成代码并记录在数据树中，生成数据树中节点的默认数据值。然后，通过从验证请求中指定的位置执行验证码来验证存储在数据树节点中的数据的内容。然后通过获取nodepath来搜索数据树，将nodepath解析成多个路径片段，基于每个路径片段搜索数据树，并且基于满足条件的搜索返回数据树的一个或多个节点路径碎片可以指定一个或多个节点或子节点的数据值来缩小搜索范围。

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