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1. 发明授权

US06819843B1 Device and method for photolithographically irradiating biological substances 有权
标题翻译：用于光刻照射生物物质的装置和方法
公开(公告)号：US06819843B1
公开(公告)日：2004-11-16
申请号：US09980194
申请日：2002-07-23
申请人： Aron Braun , Arno Heuermann
发明人： Aron Braun , Arno Heuermann
IPC分类号： G02B604
CPC分类号： B82Y30/00 , B01J19/0046 , B01J2219/00436 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00659 , B01J2219/00707 , B01J2219/00711 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , C40B40/06 , C40B40/10 , C40B60/14 , G01N21/6428 , G03F7/20 , G03F7/70275 , G03F7/70283 , G03F7/70383 , G03F7/70391
摘要： A device and a method for the photolithographic exposure of biological substances is described, which comprises at least one light source, a bundle of optical fibers and a control unit, whereby each of the optical fibers can be controlled by light independently from one another and/or light can be coupled to each fiber independently. The device is particularly suitable for the exposure of DNA, PNA or peptide chips.
摘要翻译：描述了用于生物物质的光刻曝光的装置和方法，其包括至少一个光源，一束光纤和一个控制单元，由此每个光纤可以彼此独立地控制光纤和/ 或者光可以独立地耦合到每个纤维。该装置特别适合于暴露DNA，PNA或肽芯片。

2. 发明申请

US20050037354A1 Method for epigenetic knowledge generation 审中-公开
标题翻译：表观遗传知识生成方法
公开(公告)号：US20050037354A1
公开(公告)日：2005-02-17
申请号：US10494123
申请日：2002-10-25
申请人： Kurt Berlin , Aron Braun , Peter Adorjan
发明人： Kurt Berlin , Aron Braun , Peter Adorjan
IPC分类号： C12Q1/68 , G01N33/48 , G01N33/50 , G06F15/18 , G06F19/24 , G06F19/28 , G06F19/00
CPC分类号： C12Q1/6809 , G16B40/00 , G16B50/00
摘要： A method for epigenetic knowledge generation which designs and synthesizes the chemical and/or biological components that determine the epigenetic parameters to be selected and measured is described. The value of these epigenetic parameters is determined, the steps of this procedure repeated and finally the results are stored. The present invention relates to a method of epigenetic knowledge generation comprising the steps of: a. selecting epigenetic parameters of interest; b. designing the chemical and/or biological components of the epigenetic measurement system, wherein the chemical and/or biological components determine the epigenetic parameters to be measured; c. synthesizing the variable chemical and/or biological components; d. measuring the value of the epigenetic parameters using the chemical and/or biological components; e. storing the results obtained by measurement; f. defining a subset of epigenetic parameters of interest based on the measurements; g. repeating steps a-d.
摘要翻译：描述了设计和合成确定待选择和测量的表观遗传参数的化学和/或生物组分的表观遗传知识产生的方法。确定这些表观遗传参数的值，重复该过程的步骤，最后存储结果。本发明涉及一种表观遗传知识产生方法，包括以下步骤：a。选择感兴趣的表观遗传参数; b。设计表观遗传学测量系统的化学和/或生物组分，其中所述化学和/或生物组分决定待测量的表观遗传参数; C。合成可变化学和/或生物成分; d。使用化学和/或生物成分测量表观遗传参数的值; e。存储通过测量获得的结果; F。基于测量定义感兴趣的表观遗传参数的子集; G。重复步骤a-d。

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