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1. 发明授权

US09260480B2 Process for the manufacture of Degarelix and its intermediates 有权
标题翻译： Degarelix及其中间体的制造方法
公开(公告)号：US09260480B2
公开(公告)日：2016-02-16
申请号：US13881751
申请日：2011-10-26
申请人： Dipak Kalita , Mohosin Layek , Atmakuri Venkata Dhanunjaya Rao , Venkat Aravinda Potula , Vikas Gajare , Kesavan Balakumaran , Anders Nilsson , Guangcheng Jiang
发明人： Dipak Kalita , Mohosin Layek , Atmakuri Venkata Dhanunjaya Rao , Venkat Aravinda Potula , Vikas Gajare , Kesavan Balakumaran , Anders Nilsson , Guangcheng Jiang
IPC分类号： C07K7/02 , C07K7/06 , C07K7/23 , C07K7/00 , C07K7/04 , C07K1/02 , C07K1/06 , C07K1/10 , A61K38/00 , A61K38/09 , A61K38/08 , A61K38/04 , C07K5/08
CPC分类号： C07K7/06 , A61K38/00 , A61K38/04 , A61K38/08 , A61K38/09 , C07K1/02 , C07K1/026 , C07K1/06 , C07K1/10 , C07K5/08 , C07K7/00 , C07K7/04 , C07K7/23 , Y02P20/55
摘要： The present invention relates to a liquid (or solution)-phase manufacturing process for preparing the decapeptide Degareiix, its amino-protected precursor, and other useful intermediates. The invention further relates to polypeptides useful in the solution-phase manufacturing process and to the purification of Degareiix itself. The manufacturing process comprises the step of cleaving the ε-amino protecting group Pε from a Degareiix precursor according to formula {P4)(Pε)Ac-AA1-AA10-NH2 in an organic solvent comprising the precursor and a cleaving agent dissolved therein: wherein P4 is a hydroxyl-protecting group or hydrogen, preferably hydrogen.
摘要翻译：本发明涉及用于制备十肽Degareiix，其氨基保护的前体和其它有用的中间体的液体（或溶液）相制备方法。本发明进一步涉及可用于溶液相制备方法中的多肽和Degareiix本身的纯化。制备方法包括裂解“酰氨基保护基”的步骤。由含有前体的有机溶剂中的根据式{P4）（P＆amp; Ac）AA-AA10-NH 2的去角闪ix前体衍生自其中P4是羟基保护基或氢，优选氢。

2. 发明申请

US20140351555A1 DIGITAL SIGNAL PROCESSOR AND METHOD FOR ADDRESSING A MEMORY IN A DIGITAL SIGNAL PROCESSOR 有权
标题翻译：数字信号处理器和用于寻址数字信号处理器中的存储器的方法
公开(公告)号：US20140351555A1
公开(公告)日：2014-11-27
申请号：US14364619
申请日：2012-11-28
申请人： Anders Nilsson , Eric Tell , Erik Alfredsson
发明人： Anders Nilsson , Eric Tell , Erik Alfredsson
IPC分类号： G06F9/30 , G06F9/35 , G06F12/06
CPC分类号： G06F9/30036 , G06F9/35 , G06F12/06 , G06F15/8061
摘要： In a digital signal processor comprising at least one vector execution unit and at least a first memory unit a third unit is arranged to provide addressing data in the form of an address vector to be used for addressing the first memory unit said third unit being connectable to the first memory unit through the on-chip network, in such a way that data provided from the third unit can be used to control the reading from and/or the writing to the first memory unit. This enables fast reading from and writing to a memory unit of data in any desired order.
摘要翻译：在包括至少一个向量执行单元和至少第一存储器单元的数字信号处理器中，第三单元被布置为提供地址向量形式的寻址数据，以用于寻址第一存储器单元，所述第三单元可连接到通过片上网络的第一存储器单元，使得从第三单元提供的数据可以用于控制对第一存储器单元的读取和/或写入。这使得能够以任何所需的顺序快速读取和写入数据的存储单元。

3. 发明授权

US08874968B1 Method and system for testing a processor designed by a configurator 有权
标题翻译：用于测试由配置器设计的处理器的方法和系统
公开(公告)号：US08874968B1
公开(公告)日：2014-10-28
申请号：US13458918
申请日：2012-04-27
申请人： Anders Nilsson , Eric Tell , Olof Kraigher
发明人： Anders Nilsson , Eric Tell , Olof Kraigher
IPC分类号： G06F11/00
CPC分类号： G06F11/3672
摘要： The present invention provides a system and method that includes a library module including a plurality of programmable components and at least one corresponding test case for each programmable component. The system also includes the configurator module coupled to the library module and accessing at least one of the plurality of programmable components and the at least one corresponding test case. The configurator module further outputs a code describing a processor for running a software-defined digital signal processor and includes the accessed programmable component and a plurality of interconnections linking the accessed programmable component. The system further includes a test case generator coupled to the configurator to output a test suite including the at least one corresponding test case for each accessed programmable component and a plurality of interconnect tests to test the plurality of interconnections linking the accessed programmable component.
摘要翻译：本发明提供一种系统和方法，该系统和方法包括一个库模块，该库模块包括多个可编程组件和至少一个对应的每个可编程组件的测试用例。该系统还包括耦合到库模块的配置器模块并且访问多个可编程组件和至少一个相应测试用例中的至少一个。配置器模块还输出描述用于运行软件定义的数字信号处理器的处理器的代码，并且包括所访问的可编程组件和链接所访问的可编程组件的多个互连。所述系统还包括耦合到所述配置器的测试用例发生器，以输出测试套件，所述测试套件包括用于每个可访问的可编程组件的所述至少一个相应的测试用例以及用于测试所述多个互连链接所访问的可编程组件的多个互连测试。

4. 发明授权

US08802624B2 Methods of treatment using orodispersible desmopressin pharmaceutical formulations 有权
标题翻译：使用分散性去氨加压素药物制剂的治疗方法
公开(公告)号：US08802624B2
公开(公告)日：2014-08-12
申请号：US13110619
申请日：2011-05-18
申请人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
发明人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
IPC分类号： A61K9/20 , A61K38/08
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Described herein are methods of treating diseases or conditions such as incontinence, primary nocturnal enuresis (PNE), nocturia, and central diabetes insipidus, by administering desmopressin acetate in an orodispersiblc solid dosage form that disintegrates in the mouth within 10 seconds and includes an amount of desmopressin acetate, measured as the free base, of from 10 to 600 μg.
摘要翻译：本文描述的是通过在10秒内通过在口腔中分解的直径为分散的固体剂型施用醋酸去氨加压素来治疗疾病或病症如尿失禁，原发性夜间遗尿（PNE），夜尿症和中枢性尿崩症的方法，并且包括以游离碱计，醋酸去氨加压素为10至600μg。

5. 发明授权

US08594625B2 Charging in ad-hoc communication networks 有权
标题翻译：在自组织通信网络中进行计费
公开(公告)号：US08594625B2
公开(公告)日：2013-11-26
申请号：US12441759
申请日：2007-10-11
申请人： Anders Nilsson Plymoth , Bjorn Plymoth , Amelie Plymoth
发明人： Anders Nilsson Plymoth , Bjorn Plymoth , Amelie Plymoth
IPC分类号： H04M11/00 , H04M15/00
CPC分类号： H04W4/24 , H04L12/14 , H04L12/1403 , H04W84/18 , H04W92/02
摘要： Charging is enabled in ad hoc networks, without access to external infrastructure networks. For example, when a communication is initiated by a mobile communication device within an ad hoc network, a small initiation fee is stored securely on the device, typically on a smart card. Transfer of the charging information may then occur more or less automatically and/or when the device reaches a coverage area of the operator network. The invention is also advantageous for charging in cellular and/or wireless networks, as charging can be performed with low administration costs.
摘要翻译：在ad hoc网络中启用了充电功能，无需访问外部基础架构网络。例如，当由自组织网络内的移动通信设备发起通信时，小的启动费用被安全地存储在设备上，通常在智能卡上。然后，自动地和/或当设备到达运营商网络的覆盖区域时，计费信息的传送或多或少地发生。本发明对于在蜂窝和/或无线网络中的充电也是有利的，因为可以以低的管理成本进行充电。

6. 发明申请

US20090123324A1 Iron-Base Alloy Containing Chromium-Tungsten Carbide And a Method Of Producing It 审中-公开
标题翻译：含有碳化钨的铁基合金及其生产方法
公开(公告)号：US20090123324A1
公开(公告)日：2009-05-14
申请号：US12256290
申请日：2008-10-22
申请人： Carl-Hakan Andersson , Mikael Andersson , Henrik Andersson , Helena Andersson , Anders Nilsson , Jan-Eric Stahl
发明人： Carl-Hakan Andersson , Mikael Andersson , Henrik Andersson , Helena Andersson , Anders Nilsson , Jan-Eric Stahl
IPC分类号： C22C38/52 , C22C38/30 , B22D25/00 , C22C30/00
CPC分类号： C22C33/08 , C22C37/06
摘要： A method and cast wear resistant component made of an alloy that includes carbon, tungsten, chromium, and cobalt with the balance essentially iron and other alloying components made using waste, surplus or worn-out cemented carbide product, such as cemented carbide cutting tool inserts. In one method, the alloy further includes silicon, manganese, nickel, titanium, and molybdenum. In practicing the method, pieces of waste, surplus or worn-out cemented carbide product having tungsten carbide (WC) are added to a cast iron alloy melt. The melt includes enough chromium to control solubility of the WC. In one method, precipitated carbide structure having chromium and carbon is produced with tungsten in the melt being substitutionally dissolved. In one implementation, tungsten is substitutionally dissolved in a lattice of the precipitated carbide structure. Carbide can be added to the melt via super inoculation. The cast wear resistant component can be a cutting tool.
摘要翻译：由合金制成的方法和铸造耐磨部件，其包括碳，钨，铬和钴，余量基本上为铁和其他使用废料，过剩或磨损的硬质合金产品制成的合金元件，例如硬质合金刀具插入件。在一种方法中，合金还包括硅，锰，镍，钛和钼。在实施该方法中，将具有碳化钨（WC）的废弃物，剩余或磨损的硬质合金产品块加入到铸铁合金熔体中。熔体包含足够的铬以控制WC的溶解度。在一种方法中，在熔融物中用钨制造具有铬和碳的沉淀碳化物结构被取代溶解。在一个实施方案中，钨被代替地溶解在沉淀的碳化物结构的晶格中。可以通过超级接种将硬质合金加入到熔体中。铸造耐磨部件可以是切削工具。

7. 发明申请

US20090064551A1 INFORMATION CARRIER 审中-公开
标题翻译：信息载体
公开(公告)号：US20090064551A1
公开(公告)日：2009-03-12
申请号：US11718660
申请日：2005-11-07
申请人： Erik Schroder , Anders Nilsson
发明人： Erik Schroder , Anders Nilsson
IPC分类号： G09F7/00
CPC分类号： G09F7/16
摘要： The method facilitates for an individual to orientate himself in a building including the installation of at least an information carrier at a location selected with regard to a configuration of the building. The information carrier includes a visual representation of at least a section of a floor of the building and at least some information associated with the building. The visual representation is a perspective view of the section of the floor.
摘要翻译：该方法有助于个人在建筑物中定向自己，包括至少在关于建筑物的配置选择的位置处安装信息载体。信息载体包括建筑物的至少一部分的视觉表示以及与建筑物相关联的至少一些信息。视觉表示是地板部分的透视图。

8. 发明授权

US07442261B2 Iron-base alloy containing chromium-tungsten carbide and a method of producing it 失效
标题翻译：含有碳化钨的铁基合金及其制造方法
公开(公告)号：US07442261B2
公开(公告)日：2008-10-28
申请号：US10276943
申请日：2001-05-15
申请人： Mikael Andersson, legal representative , Henrik Andersson, legal representative , Helena Andersson, legal representative , Anders Nilsson , Jan-Eric Ståhl
发明人： Carl-Håkan Andersson
IPC分类号： C22C38/28 , C22C38/18 , C22C33/06
CPC分类号： C22C33/08 , C22C37/06
摘要： In a method of producing an iron-based alloy containing chromium carbide, pieces of cemented carbide are added to an iron-based melt containing carbon, e.g. cast iron. Chromium, which regulates the solution of WC into the melt, is also added. The molten alloy is then cast. An alloy comprising chromium-tungsten-carbide in a ferrous matrix is produced. Uses of the alloy are claimed.
摘要翻译：在制造含有碳化铬的铁基合金的方法中，将硬质合金块加到含有碳的铁基熔体中，铸铁。还加入了将WC调节到熔体中的铬。然后浇铸熔融合金。生产含铁基碳化钨的合金。要求使用合金。

9. 发明申请

US20080147009A1 VASCULAR ACCESS DEVICE BLOOD SEALING AND EXPOSURE PREVENTION 有权
标题翻译：血管通路装置血液密封和接触预防
公开(公告)号：US20080147009A1
公开(公告)日：2008-06-19
申请号：US11943352
申请日：2007-11-20
申请人： Bengt Erik Anders Nilsson , Janne Joakim Lundqvist , Kristoffer Glowacki , Karl Johan Marten Soderholm , Lars-Ake Lennart Larsson , Johan Fredrik Thorne
发明人： Bengt Erik Anders Nilsson , Janne Joakim Lundqvist , Kristoffer Glowacki , Karl Johan Marten Soderholm , Lars-Ake Lennart Larsson , Johan Fredrik Thorne
IPC分类号： A61M5/32
CPC分类号： A61M25/0637 , A61M5/3275 , A61M25/0606 , A61M25/0625 , A61M2005/3247
摘要： An extravascular system for accessing the vasculature of a patient including a catheter having an interior surface, a needle disposed within the catheter, and/or a needle cap defining at least one capillary space and including a flexible seal surrounding the at least one capillary space. The flexible seal may engage the interior surface of the catheter. A method of controlling exposure to a liquid from an extravascular system including providing a wicking material positioned adjacent to a flow channel such that any fluid located external to the flow channel is retained by the wicking material. The wicking material may be incorporated into any extravascular system where exposure to liquids is undesirable.
摘要翻译：用于进入患者脉管系统的血管外系统，包括具有内表面的导管，设置在导管内的针和/或限定至少一个毛细管空间的针帽，并且包括围绕至少一个毛细管空间的柔性密封件。柔性密封件可以接合导管的内表面。一种控制从血管外系统暴露于液体的方法，包括提供邻近流动通道定位的芯吸材料，使得位于流动通道外部的任何流体被芯吸材料保持。芯吸材料可以并入任何血管外系统，其中不希望接触液体。

10. 发明申请

US20060271764A1 Programmable digital signal processor including a clustered SIMD microarchitecture configured to execute complex vector instructions 有权
标题翻译：可编程数字信号处理器包括配置成执行复矢量指令的集群SIMD微体系结构
公开(公告)号：US20060271764A1
公开(公告)日：2006-11-30
申请号：US11201842
申请日：2005-08-11
申请人： Anders Nilsson , Eric Tell , Dake Liu
发明人： Anders Nilsson , Eric Tell , Dake Liu
IPC分类号： G06F15/00
CPC分类号： G06F9/30079 , G06F9/30014 , G06F9/30036 , G06F9/3851 , G06F9/3885 , G06F9/3891 , G06F15/7842 , G06F15/8092
摘要： A programmable digital signal processor including a clustered SIMD microarchitecture includes a plurality of accelerator units, a processor core and a complex computing unit. Each of the accelerator units may be configured to perform one or more dedicated functions. The processor core includes an integer execution unit that may be configured to execute integer instructions. The complex computing unit may be configured to execute complex vector instructions. The complex computing unit may include a first and a second clustered execution pipeline. The first clustered execution pipeline may include one or more complex arithmetic logic unit datapaths configured to execute first complex vector instructions. The second clustered execution pipeline may include one or more complex multiplier accumulator datapaths configured to execute second complex vector instructions.
摘要翻译：包括集群SIMD微体系结构的可编程数字信号处理器包括多个加速器单元，处理器核和复合计算单元。每个加速器单元可以被配置为执行一个或多个专用功能。处理器核心包括可被配置为执行整数指令的整数执行单元。复合计算单元可以被配置为执行复向量指令。复合计算单元可以包括第一和第二群集执行流水线。第一群集执行流水线可以包括被配置为执行第一复合向量指令的一个或多个复杂算术逻辑单元数据路径。第二群集执行流水线可以包括被配置为执行第二复合向量指令的一个或多个复数乘法器累加器数据路径。

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