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1. 发明授权

US09754077B2 Systems and methods for disease control and management 有权
公开(公告)号：US09754077B2
公开(公告)日：2017-09-05
申请号：US12071486
申请日：2008-02-21
申请人： Ryan A. Sysko , Suzanne K. Sysko , James M. Minor , Anand Iyer , Andrew Fletcher
发明人： Ryan A. Sysko , Suzanne K. Sysko , James M. Minor , Anand Iyer , Andrew Fletcher
IPC分类号： G06Q10/00 , G06Q50/00 , G06F19/00 , G06Q50/24
CPC分类号： G06F19/325 , G06F19/00 , G06Q50/24 , G16H50/50
摘要： Methods, computer-readable media, and systems for providing disease management. In one implementation, a system develops a treatment recommendation for a patient based on patient data. The system may receive patient data, execute a basic model of the physiological system of the patient to generate a modified model for the patient based on the patient data, perform a statistical analysis of the patient data to detect data excursions of the parameter values; use the modified model to determine factors causing the data excursions; and use the model to develop a treatment recommendation to ameliorate negative effects of the disease.

2. 发明申请

US20080195174A1 SYSTEMS AND METHODS FOR ELECTRICAL STIMULATION OF BLOOD VESSELS 失效
标题翻译：血管电刺激系统与方法
公开(公告)号：US20080195174A1
公开(公告)日：2008-08-14
申请号：US11674463
申请日：2007-02-13
申请人： Joseph Walker , Rodney W. Salo , Anand Iyer , Joseph M. Pastore , Eric Mokelke
发明人： Joseph Walker , Rodney W. Salo , Anand Iyer , Joseph M. Pastore , Eric Mokelke
IPC分类号： A61N1/36
CPC分类号： A61N1/36114 , A61N1/36117
摘要： Disclosed herein, among other things, is a system for electrical stimulation of blood vessels. An embodiment of the system includes at least one electrode having electrical contact with a blood vessel. The embodiment also includes a stimulation circuit electrically connected to the electrode, the circuit adapted to provide stimulation to the vessel. The embodiment further includes a controller connected to the circuit, the controller adapted to select frequency and voltage parameters for the stimulation circuit to selectively affect vascular therapy, including constriction of the vessel and dilation of the vessel. According to various embodiments, the stimulation circuit and controller are contained within an implantable medical device (IMD). The system also includes a sensor connected to the controller, and the controller initiates and adjusts therapy based on a signal received from the sensor, in varying embodiments.
摘要翻译：此处公开的是用于电刺激血管的系统。该系统的一个实施例包括至少一个与血管电接触的电极。该实施例还包括电连接到电极的刺激电路，该电路适于向容器提供刺激。该实施例还包括连接到电路的控制器，所述控制器适于选择用于刺激电路的频率和电压参数，以选择性地影响血管治疗，包括容器收缩和血管扩张。根据各种实施例，刺激电路和控制器被包含在可植入医疗装置（IMD）内。该系统还包括连接到控制器的传感器，并且在不同的实施例中，控制器基于从传感器接收的信号来启动和调整治疗。

3. 发明申请

US20070212976A1 Smart polishing media assembly for planarizing substrates 审中-公开
标题翻译：用于平坦化基板的智能抛光介质组件
公开(公告)号：US20070212976A1
公开(公告)日：2007-09-13
申请号：US11374250
申请日：2006-03-13
申请人： Peter McReynolds , Gregory Menk , Benjamin Bonner , Gopalakrishna Prabhu , Erik Rondum , Garlen Leung , Anand Iyer
发明人： Peter McReynolds , Gregory Menk , Benjamin Bonner , Gopalakrishna Prabhu , Erik Rondum , Garlen Leung , Anand Iyer
IPC分类号： B24B51/00 , B24B49/00 , B24D11/00
CPC分类号： B24B21/004 , B24B37/20
摘要： A smart polishing media assembly is provided, along with a polishing system and a method for using the same. In one embodiment, the smart polishing media assembly includes a memory device coupled to a polishing material. The polishing material may be in pad, web or belt form. The memory device generally stores at least one material information, historical use information, and/or conditioning information of the polishing material.
摘要翻译：提供了一种智能抛光介质组件，以及抛光系统及其使用方法。在一个实施例中，智能抛光介质组件包括耦合到抛光材料的存储器件。抛光材料可以是垫，网或带形式。存储装置通常存储抛光材料的至少一种材料信息，历史使用信息和/或调理信息。

4. 发明申请

US20070197134A1 Polishing article with integrated window stripe 审中-公开
标题翻译：具有集成窗口条纹的抛光物品
公开(公告)号：US20070197134A1
公开(公告)日：2007-08-23
申请号：US11707551
申请日：2007-02-15
申请人： Gregory Menk , Peter McReynolds , Erik Rondum , Anand Iyer , Gopalakrishna Prabhu , Garlen Leung
发明人： Gregory Menk , Peter McReynolds , Erik Rondum , Anand Iyer , Gopalakrishna Prabhu , Garlen Leung
IPC分类号： B24B49/00
CPC分类号： B24B21/06 , B24B21/04 , B24B21/12 , B24B37/12 , B24B37/205 , B24B37/26 , B24D11/001
摘要： A polishing article is described. The polishing article includes an elongated polishing layer, and a transparent carrier layer supporting the polishing layer, where the transparent carrier layer has a projection extending into an aperture in the polishing layer to provide a transparent window in the polishing layer.
摘要翻译：描述抛光制品。抛光制品包括细长的抛光层和支撑抛光层的透明载体层，其中透明载体层具有延伸到抛光层中的孔中的突起，以在抛光层中提供透明窗口。

5. 发明申请

US20070191906A1 METHOD AND APPARATUS FOR SELECTIVE NERVE STIMULATION 审中-公开
标题翻译：选择性神经刺激的方法和装置
公开(公告)号：US20070191906A1
公开(公告)日：2007-08-16
申请号：US11276066
申请日：2006-02-13
申请人： Anand Iyer , Rodney Salo , Anthony Caparso , Paul Haefner
发明人： Anand Iyer , Rodney Salo , Anthony Caparso , Paul Haefner
IPC分类号： A61N1/00
CPC分类号： A61N7/00 , A61N1/362 , A61N1/40 , A61N5/02 , A61N2007/0026 , A61N2007/0078 , A61N2007/0095
摘要： Various aspects relate to a device. Various device embodiments include at least a first and a second transducer, and a controller. The first transducer is adapted to be positioned to direct a first energy wave toward a neural target, and the second transducer is adapted to be positioned to direct a second energy wave toward the neural target. The controller is connected to the transducers to generate the first energy wave with a first predetermined phase and a first predetermined amplitude from the first transducer and to generate the second energy wave with a second predetermined phase and a second predetermined amplitude from the second transducer. The amplitudes are selected so that a neural stimulation threshold is reached only during constructive wave interference. The phases are selected so that the first and second energy waves constructively interfere at the neural target. Other aspects and embodiments are provided herein.
摘要翻译：各个方面涉及一种装置。各种装置实施例包括至少第一和第二换能器以及控制器。第一传感器适于被定位成将第一能量波导向神经目标，并且第二换能器适于被定位成将第二能量波导向神经目标。控制器连接到换能器以产生具有来自第一换能器的第一预定相位和第一预定振幅的第一能量波，并且从第二换能器产生具有第二预定相位和第二预定振幅的第二能量波。选择振幅使得仅在建构性波干扰期间才达到神经刺激阈值。选择相位使得第一和第二能量波构造地干扰神经目标。本文提供了其它方面和实施例。

6. 发明申请

US20070218693A1 HIGH SELECTIVITY SLURRY COMPOSITIONS FOR CHEMICAL MECHANICAL POLISHING 审中-公开
标题翻译：高选择性浆料组合物化学机械抛光
公开(公告)号：US20070218693A1
公开(公告)日：2007-09-20
申请号：US11750897
申请日：2007-05-18
申请人： Benjamin Bonner , Anand Iyer , Olivier Nguyen , Donald Chua , Christopher Lee , Shijian Li
发明人： Benjamin Bonner , Anand Iyer , Olivier Nguyen , Donald Chua , Christopher Lee , Shijian Li
IPC分类号： C09G1/00
CPC分类号： H01L21/31053 , C09G1/02 , C09K3/1463
摘要： A chemical-mechanical polishing composition that includes less than about 1% wt. abrasive, an additive, and water, where a weigh percent of the additive is greater than a weight percent of the abrasive. Also, a method of polishing a semiconductor substrate in a shallow trench isolation process, the method including contacting the substrate with a polishing pad of a polishing apparatus while applying a high selectivity slurry to the polishing pad, where the slurry comprises less than about 1% wt. abrasive, an additive, and water, and where a weigh percent of the additive is greater than a weight percent of the abrasive. Also, a method of making a chemical-mechanical polishing slurry composition, the method including adding together an abrasive, an additive and water to form the slurry, where a weigh percent of the additive is greater than a weight percent of the abrasive, and the abrasive and additive together comprise less than 2% by wt. of the slurry.
摘要翻译：化学机械抛光组合物，其包含小于约1重量％研磨剂，添加剂和水，其中添加剂的重量百分比大于研磨剂的重量百分比。此外，在浅沟槽隔离工艺中抛光半导体衬底的方法，该方法包括使衬底与抛光装置的抛光垫接触，同时向抛光垫施加高选择性浆料，其中浆料包含小于约1％重量研磨剂，添加剂和水，并且其中添加剂的重量百分比大于研磨剂的重量百分比。另外，制备化学 - 机械抛光浆料组合物的方法，该方法包括将研磨剂，添加剂和水相加以形成浆料，其中添加剂的重量百分比大于磨料的重量百分数，并且研磨剂和添加剂一起包含小于2重量％。的浆料。

7. 发明申请

US20070197133A1 Polishing article with integrated window stripe 失效
标题翻译：具有集成窗口条纹的抛光物品
公开(公告)号：US20070197133A1
公开(公告)日：2007-08-23
申请号：US11707548
申请日：2007-02-15
申请人： Gregory Menk , Peter McReynolds , Erik Rondum , Anand Iyer , Gopalakrishna Prabhu , Garlen Leung
发明人： Gregory Menk , Peter McReynolds , Erik Rondum , Anand Iyer , Gopalakrishna Prabhu , Garlen Leung
IPC分类号： B24B49/00 , B24B1/00 , B24D11/00
CPC分类号： B24B21/06 , B24B21/04 , B24B21/12 , B24B37/12 , B24B37/205 , B24B37/26 , B24D11/001
摘要： A method is described. The method includes contacting a non-solid material to a non-linear edge of a sheet of polishing material, and causing the non-solid material to solidify to form a window that contacts the non-linear edge of the polishing material.
摘要翻译：描述了一种方法。该方法包括使非固体材料与抛光材料片的非线性边缘接触，并使非固体材料固化以形成接触抛光材料的非线性边缘的窗口。

8. 发明授权

US08442639B2 Systems and methods for electrical stimulation of blood vessels 失效
标题翻译：电刺激血管的系统和方法
公开(公告)号：US08442639B2
公开(公告)日：2013-05-14
申请号：US11674463
申请日：2007-02-13
申请人： Joseph Walker , Rodney W. Salo , Anand Iyer , Joseph M. Pastore , Eric Mokelke
发明人： Joseph Walker , Rodney W. Salo , Anand Iyer , Joseph M. Pastore , Eric Mokelke
IPC分类号： A61N1/00 , A61B5/04
CPC分类号： A61N1/36114 , A61N1/36117
摘要： Disclosed herein, among other things, is a system for electrical stimulation of blood vessels. An embodiment of the system includes at least one electrode having electrical contact with a blood vessel. The embodiment also includes a stimulation circuit electrically connected to the electrode, the circuit adapted to provide stimulation to the vessel. The embodiment further includes a controller connected to the circuit, the controller adapted to select frequency and voltage parameters for the stimulation circuit to selectively affect vascular therapy, including constriction of the vessel and dilation of the vessel. According to various embodiments, the stimulation circuit and controller are contained within an implantable medical device (IMD). The system also includes a sensor connected to the controller, and the controller initiates and adjusts therapy based on a signal received from the sensor, in varying embodiments.
摘要翻译：此处公开的是用于电刺激血管的系统。该系统的一个实施例包括至少一个与血管电接触的电极。该实施例还包括电连接到电极的刺激电路，该电路适于向容器提供刺激。该实施例还包括连接到电路的控制器，所述控制器适于选择用于刺激电路的频率和电压参数，以选择性地影响血管治疗，包括容器收缩和血管扩张。根据各种实施例，刺激电路和控制器被包含在可植入医疗装置（IMD）内。该系统还包括连接到控制器的传感器，并且在不同的实施例中，控制器基于从传感器接收的信号来启动和调整治疗。

9. 发明申请

US20070264257A1 Immunotherapy of autoimmune disorders 审中-公开
标题翻译：免疫治疗自身免疫性疾病
公开(公告)号：US20070264257A1
公开(公告)日：2007-11-15
申请号：US11246541
申请日：2005-10-11
申请人： Kyriaki Dunussi-Joannopoulos , Anand Iyer
发明人： Kyriaki Dunussi-Joannopoulos , Anand Iyer
IPC分类号： A61K39/395 , A61K45/00 , A61P37/00
CPC分类号： C07K16/2803 , A61K47/6849 , A61K2039/505
摘要： Compositions and methods for treating autoimmune diseases are described. In particular, the use of B cell depleting agents and cytotoxic drug/B cell depleting agent conjugates with a drug loading significantly higher than in previously reported procedures and with decreased aggregation and low conjugate fraction (LCF) in treating autoimmune diseases is described. Combination therapies and compositions for treating autoimmune diseases, including the B cell depleting agents, conjugates and/or anti-cytokine agents, are also described.
摘要翻译：描述了治疗自身免疫疾病的组合物和方法。特别地，描述了使用B细胞消耗剂和细胞毒性药物/ B细胞消耗剂缀合物，其药物负载量显着高于先前报道的方法，并且在治疗自身免疫性疾病中具有降低的聚集和低结合部分（LCF）。还描述了用于治疗自身免疫疾病的组合疗法和组合物，包括B细胞消耗剂，缀合物和/或抗细胞因子剂。

10. 发明申请

US20070136126A1 System and method for multi-enterprise supply chain optimization 有权
标题翻译：多企业供应链优化的制度与方法
公开(公告)号：US20070136126A1
公开(公告)日：2007-06-14
申请号：US11634056
申请日：2006-12-05
申请人： Ranjit Notani , Shrikant Ranade , Nitin Goyal , Anand Iyer
发明人： Ranjit Notani , Shrikant Ranade , Nitin Goyal , Anand Iyer
IPC分类号： G07G1/00
CPC分类号： G06Q10/087 , G06Q10/06 , G06Q10/06312 , G06Q10/06315 , G06Q10/06375 , G06Q30/0202 , G06Q30/0206 , G06Q30/0603 , G06Q40/12 , G06Q50/188
摘要： A method of optimizing multi-enterprise supply chain agreements using an electronic scenario based option contract includes creating at a buyer computer a plurality of scenarios of forecasted demand for one or more products and communicating from the buyer computer to a seller computer an offer to enter into an option contract for the supply of the one or more products, the option contract including an option corresponding to each of the plurality of scenarios of forecasted demand. The method further includes executing the option contract, receiving at the buyer computer an indication of current buyer demand for at least one scenario associated with the one or more products, and exercising at least a portion of the option in the option contract based at least in part on the indicated buyer demand.
摘要翻译：使用基于电子场景的期权合约来优化多企业供应链协议的方法包括在买方计算机上创建多个对一个或多个产品的预测需求的场景，并从买方计算机向卖方计算机通信以进入一种或多种产品供应的期权合约，期权合约包括与预测需求的多种情景中的每一种对应的期权。该方法还包括执行期权合约，在买方计算机处收到当前买方对与一个或多个产品相关联的至少一个场景的需求的指示，以及至少在以下操作中行使期权合约中的期权的至少一部分：部分指示买家需求。

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