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    • 1. 发明授权
    • Enhanced drop mixing using magnetic actuation
    • 使用磁力驱动增强液滴混合
    • US08617899B2
    • 2013-12-31
    • US12031519
    • 2008-02-14
    • Dirk De BruykerAli Asgar Saleem BhagatAlan G. BellMichael I. RechtFrancisco E. Torres
    • Dirk De BruykerAli Asgar Saleem BhagatAlan G. BellMichael I. RechtFrancisco E. Torres
    • G01N25/20G01N27/00G01N25/00C12M1/02
    • B01F13/0818B01F13/0071B01F13/0076B01F13/0077B01F2015/0221G01N25/48Y10T137/0318Y10T137/87652Y10T436/25Y10T436/2575
    • A method and device for merging and mixing at least two separate and distinct fluid drops on a substrate, includes a drop merging area on the surface, where a first magnetic material is placed at a first location. A first drop of fluid is then placed at the first location on the surface, resulting in the first magnetic material being at least partially positioned within the first drop of fluid. A second drop of fluid is then placed at a second location on the surface of the drop merging area. A magnetic field is applied by a varying magnetic field generator to at least a portion of the drop merge area of the substrate, which includes at least the first location on the substrate. The varying magnetic field will act on the first magnetic material to move the first magnetic material within the first drop of fluid, causing a stirring of the fluid. A drop merging force from a drop merging mechanism is applied to at least one of the first drop of fluid and the second drop of fluid within the drop merge area. This causes at least one of the first drop of fluid and the second drop of fluid to move toward the other and make contact. The internal stirring of the fluid in the first drop of fluid by the movement of the magnetic material enhances the mixing of the constituents of the first drop of fluid and the constituents of the second drop of fluid.
    • 用于在衬底上合并和混合至少两个独立且不同的液滴的方法和装置包括在表面上的液滴合并区域,其中第一磁性材料放置在第一位置。 然后将第一滴流体放置在表面上的第一位置处,导致第一磁性材料至少部分地定位在第一液滴内。 然后将第二滴流体放置在滴液合并区域的表面上的第二位置。 通过变化的磁场发生器将磁场施加到衬底的下落合并区域的至少一部分,其至少包括衬底上的第一位置。 变化的磁场将作用在第一磁性材料上以使第一磁性材料在第一液滴内移动,引起流体的搅拌。 来自液滴合并机构的液滴合并力被施加到液滴合并区域中的第一液体流体和第二液体流中的至少一个。 这使得第一液体流体和第二液体液滴中的至少一个朝向另一个流体移动并进行接触。 通过磁性材料的运动在第一滴流体中内部流体的内部搅拌增强了第一滴流体的组分与第二滴流体的组分的混合。