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    • 1. 发明申请
    • Composition Based On Zeolite And Usage As Lick Stone
    • 基于沸石和作为舔石的用途的组合
    • US20120059068A1
    • 2012-03-08
    • US13320896
    • 2009-11-05
    • Stephan Hugo FreiAlfred Ernst Gehring
    • Stephan Hugo FreiAlfred Ernst Gehring
    • A23K1/175A23P1/10A61K47/02
    • A23K50/10A23K20/28
    • The invention lies in the field of environmental technology and relates to a compound, in particular for the use, in particular as metabolically inert gas absorber for ruminants on the basis of zeolite, salt and a binding agent. It furthermore relates to a licking element with such a composition, a process for the production of such a licking element as well as its application. The use of zeolite relieves the organism of toxic substances, such as heavy metals and toxins. Clinoptilolite is a dietetically working ballast material, which stabilises the intestinal activities without depriving the body of nutrients such as vitamins and trace elements. Thus it is possible to achieve a reduction of the gas expulsion from the digestive tract. The licking element can be set up in the open, so that even free-ranging animals that belong to a farm can be reached in an easy manner.
    • 本发明在于环境技术领域,涉及一种化合物,特别是特别用于基于沸石,盐和粘合剂的反刍动物的代谢惰性气体吸收剂。 此外,本发明还涉及具有这种组合物的舔元件,用于生产这种舔元件的方法及其应用。 使用沸石可以释放生物体中的有毒物质,如重金属和毒素。 斜发沸石是一种节食性的工作压载物质,其可以稳定肠道活性,而不会剥夺身体的营养物质,如维生素和微量元素。 因此,可以实现从消化道排出的气体的减少。 舔元素可以建立在开放的环境中,使得属于农场的甚至自由的动物可以轻松地到达。
    • 3. 发明申请
    • Method and device for obtaining a determined flow resistance of a flow channel
    • 用于获得确定的流动通道的流动阻力的方法和装置
    • US20050076488A1
    • 2005-04-14
    • US10503447
    • 2003-01-23
    • Peter GosgerArmin WaltherPatrick MattAlfred Ernst
    • Peter GosgerArmin WaltherPatrick MattAlfred Ernst
    • B23H9/00B23H9/16C25D7/04F02M61/16F02M65/00B23Q17/00G01M19/00
    • F02M65/001B23H9/00B23H9/16C25D7/04F02M61/168F02M2200/9038Y10T29/49771Y10T29/49776Y10T29/53022
    • A diagnostic reagent for use in the evaluation of a pharmacological effect of a medicine containing a pharmaceutical agent including an enzyme, an enzyme inhibitor or a receptor ligand or a prodrug of the pharmaceutical agent; and a method of screening pharmaceutical agents each comprising an enzyme, an enzyme inhibitor or a receptor ligand and/or prodrugs of the pharmaceutical agents for one or noes having high medicative efficacy and/or a small side effect are provided. The diagnostic regent and the reagent used in the method comprise: (a) a compound which serves as a substrate for the enzyme contained in the medicine or the pharmaceutical agent to be evaluated or for an enzyme generated from the prodrug contained in the medicine or the pharmaceutical agent to be evaluated, or a pharmaceutically acceptable salt thereof; (b) a compound which serves as a substrate for a different enzyme capable of exhibiting an alteration in activity by coupling to the effect of the enzyme in (a), or a pharmaceutically acceptable salt thereof; (c) a compound which serves as a substrate for an enzyme which is directly inhibited by the enzyme inhibitor contained in the medicine or the pharmaceutical agent to be evaluated or by an enzyme inhibitor generated from the prodrug contained in the medicine or the pharmaceutical agent to be evaluated, or a pharmaceuticcallly acceptable salt thereof; (d) a compound which serves as a substrate for an enzyme capable of exhibiting an alteration in activity by coupling to the effect of the enzyme inhibitor in (c), or a pharmaceutically acceptable salt thereof; (e) a compound which serves as a substrate for an enzyme capable of exhibiting an alteration in activity by the binding between a receptor
    • 一种诊断试剂,其用于评价含有酶,酶抑制剂或受体配体或药剂前药的药剂的药物的药理作用; 并且提供了一种筛选药物的方法,每种药物包含酶,酶抑制剂或受体配体和/或具有高药效和/或副作用小的药物的药物前药。 该方法中使用的诊断试剂和试剂包括:(a)用作待评估的药物或药物中所含的酶的底物的化合物或由药物中所含的前药产生的酶或 待评价的药剂或其药学上可接受的盐; (b)通过与(a)中的酶的作用偶联而能够表现出活性变化的不同酶的底物的化合物或其药学上可接受的盐; (c)用作酶的底物的化合物,其由药物中所含的酶抑制剂或待评价的药剂直接抑制,或由药物或药剂中所含的前药产生的酶抑制剂 被评估,或其药学上可接受的盐; (d)通过与(c)中的酶抑制剂的作用偶联的能够显示活性变化的酶作为底物的化合物或其药学上可接受的盐; (e)用作能够通过受体之间的结合显示出活性变化的酶的底物的化合物
    • 7. 发明授权
    • Plate heat exchanger
    • 板式换热器
    • US09546825B2
    • 2017-01-17
    • US13620769
    • 2012-09-15
    • Gerd AbkerAlfred ErnstBernd MüllerKlaus Mönig
    • Gerd AbkerAlfred ErnstBernd MüllerKlaus Mönig
    • F28F3/04F28D9/00F28F9/02F28F13/08
    • F28D9/0037F28F3/044F28F9/0268F28F13/08F28F2250/104
    • A plate heat exchanger has flow channels through which a first flow and a second flow pass in concurrent or countercurrent flow. The flow channels are formed for the first medium between individual plates (1) joined together to form in each case a pair (P) of plates, and for the second medium between pairs (P) of plates joined together to form a stack (S) of plates, wherein the individual plates (1) within an inlet region (E) have guide blades (2) which are formed by stamped embossments and protrude into the flow channel, wherein the guide blades (2) are formed in an arch-shaped manner with an inflow leg (21) aligned substantially parallel to the main flow direction and an outflow leg (22) aligned at an angle to the inflow leg (21).
    • 板式换热器具有流动通道,第一流和第二流通过该通道并流或逆流。 在第一介质上形成流动通道,该第一介质在连接在一起的各个板(1)之间形成一对(P)板,并且在连接在一起的板对(P)之间的第二介质形成堆叠(S ),其中在入口区域(E)内的单个板(1)具有通过冲压压花形成并突出到流动通道中的引导叶片(2),其中所述导向叶片(2)形成为拱形 - 具有基本上平行于主流动方向排列的流入支脚(21)和与流入支脚(21)成一角度排列的流出支柱(22)。
    • 9. 发明申请
    • HARDNESS TESTER WITH INDENTER OF HARD METAL OR COMPOUND AND OSCILLATING CROWN FOR TESTING AT HIGH LOAD AND METHOD OF COMPARATIVE ASSESMENT OF THE HARDNESS/DEPTH PROFILE
    • 硬质金属或复合材料的硬度测试仪和用于高负荷测试的振动试验机和硬度/深度型材比较方法的比较方法
    • US20090107221A1
    • 2009-04-30
    • US11573173
    • 2004-07-02
    • Alfred ErnstErik Ernst
    • Alfred ErnstErik Ernst
    • G01N3/42
    • G01N3/42G01N2203/0098
    • A device for detecting the depth of penetration of the tip of an indenter of a hardness tester has a terminal crown turnable and slantable with respect to a cylindrical body of a reference sleeve, terminating with two spikes extending from diametrically opposed positions of a circular end surface of the terminal crown, the vertexes of which bear on the surface of the piece to be tested. The terminal crown having an end retained within the body of the sleeve and an inner circular surface defining a cuspid along a diameter orthogonal to the diameter of alignment of said two spikes, abutting on a planar circular end surface of the retaining body of the sleeve such to determine a linear or fulcrum abutment along diametrically aligned vertexes of said cuspid. The tester uses an indenter of a hard metal or compound by periodically recalibrating a hardness tester in function of said depth of penetration originally established on a reference sample of known and homogenous hardness. A method of deriving a hardness profile in terms of Vickers points for a certain depth by using the hardness tester is also described.
    • 用于检测硬度计的压头尖端的穿透深度的装置具有相对于基准套筒的圆筒体可转动和倾斜的端子顶端,其终止于从圆形端面的径向相对位置延伸的两个尖峰 的顶端,其顶点承载在待测试件的表面上。 具有保持在套筒主体内的端部的端部冠部和沿着与所述两个钉钉的对准直径正交的直径限定尖端的内圆形表面,该胎冠抵靠在套筒的保持体的平坦的圆形端表面上, 以确定沿所述尖端的沿直线对准的顶点的直线或支点基台。 测试仪使用硬质金属或化合物的压头,通过定期重新校准硬度计,其功能在于原始建立在已知和均匀硬度的参考样品上的渗透深度。 还描述了通过使用硬度计从维氏点得出某一深度的硬度分布的方法。