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1. 发明授权

US09189679B2 Age estimation method and sex determination method 有权
标题翻译：年龄估计方法和性别确定方法
公开(公告)号：US09189679B2
公开(公告)日：2015-11-17
申请号：US13805139
申请日：2011-05-18
申请人： Kazuhiro Yamazaki , Akihiro Tada , Mariko Hayashi , Miho Ohata , Sakura Torii
发明人： Kazuhiro Yamazaki , Akihiro Tada , Mariko Hayashi , Miho Ohata , Sakura Torii
IPC分类号： G06K9/00 , G06K9/36 , G06T7/00
CPC分类号： G06K9/00228 , G06K9/00221 , G06K2009/00322 , G06T7/0012 , G06T2207/30088 , G06T2207/30201
摘要： Disclosed are novel techniques for high-precision sex determination and age estimation using facial images. The disclosed age estimation method includes: a step in which facial image data of a subject is acquired; a step in which spatial frequency intensities are calculated from the acquired facial image data; and a step in which the estimated age of the subject is calculated by applying the calculated spatial frequency intensities obtained from the facial image data.
摘要翻译：公开了使用面部图像的高精度性别确定和年龄估计的新颖技术。公开的年龄估计方法包括：获取对象的面部图像数据的步骤; 从所获取的面部图像数据计算空间频率强度的步骤; 以及通过应用从面部图像数据获得的计算出的空间频率强度来计算被摄体的估计年龄的步骤。

2. 发明申请

US20130089245A1 AGE ESTIMATION METHOD AND SEX DETERMINATION METHOD 有权
标题翻译：年龄估计方法和性别决定方法
公开(公告)号：US20130089245A1
公开(公告)日：2013-04-11
申请号：US13805139
申请日：2011-05-18
申请人： Kazuhiro Yamazaki , Akihiro Tada , Mariko Hayashi , Miho Ohata , Sakura Torii
发明人： Kazuhiro Yamazaki , Akihiro Tada , Mariko Hayashi , Miho Ohata , Sakura Torii
IPC分类号： G06K9/00
CPC分类号： G06K9/00228 , G06K9/00221 , G06K2009/00322 , G06T7/0012 , G06T2207/30088 , G06T2207/30201
摘要： Disclosed are novel techniques for high-precision sex determination and age estimation using facial images. The disclosed age estimation method includes: a step in which facial image data of a subject is acquired; a step in which spatial frequency intensities are calculated from the acquired facial image data; and a step in which the estimated age of the subject is calculated by applying the calculated spatial frequency intensities obtained from the facial image data.
摘要翻译：公开了使用面部图像的高精度性别确定和年龄估计的新颖技术。公开的年龄估计方法包括：获取对象的面部图像数据的步骤; 从所获取的面部图像数据计算空间频率强度的步骤; 以及通过应用从面部图像数据获得的计算出的空间频率强度来计算被摄体的估计年龄的步骤。

3. 发明申请

US20090030070A1 EXTERNAL PREPARATION FOR SKIN CONTAINING FLAVANONE DERIVATIVE 审中-公开
标题翻译：含有FLAVANONE衍生物的皮肤外用制剂
公开(公告)号：US20090030070A1
公开(公告)日：2009-01-29
申请号：US12162961
申请日：2007-02-15
申请人： Naoko Kida , Akihiro Tada , Akiko Kanamaru
发明人： Naoko Kida , Akihiro Tada , Akiko Kanamaru
IPC分类号： A61K31/353 , A61K8/49 , C12Q1/02 , C07D311/22 , A61P17/16 , A61Q19/00
CPC分类号： A61K8/498 , A61K31/352 , A61K36/38 , A61Q19/00 , A61Q19/08 , G01N33/5044 , G01N2333/78
摘要： To increase a tissue regeneration ability of a living body such as a collagens production ability of fibroblast in the dermis in a skin defect area typified by a large wrinkle or wound, a flavanone derivative such as farrerol is used as an active ingredient of an external preparation for skin. Further, to efficiently screen a substance having an excellent effect on promoting wound healing, the remodeling action of collagen fiber bundle is tested by using skin wound model.
摘要翻译：为了增加生物体的组织再生能力，例如胶原蛋白在由大皱纹或伤口表现的皮肤缺陷区域中的真皮中的成纤维细胞的生产能力，使用黄烷酮衍生物如福乐灵作为外用制剂的活性成分为皮肤。此外，为了有效地筛选对促进伤口愈合具有优异效果的物质，通过使用皮肤伤口模型测试胶原纤维束的重塑作用。

4. 发明授权

US06756485B2 Process for preparing a monoazo metal complex salt compound for charge control agent and toner for developing electrostatic images 失效
标题翻译：制备用于电荷控制剂的单偶氮金属络盐化合物和用于显影静电图像的调色剂的方法
公开(公告)号：US06756485B2
公开(公告)日：2004-06-29
申请号：US10364443
申请日：2003-02-11
申请人： Masashi Yasumatsu , Akihiro Tada , Shun-ichiro Yamanaka
发明人： Masashi Yasumatsu , Akihiro Tada , Shun-ichiro Yamanaka
IPC分类号： C09B4501
CPC分类号： G03G9/091 , C09B29/02 , C09B29/103 , C09B45/22 , G03G9/09783
摘要： Charge control agent comprising a metal complex salt compound of Formula (I) containing substantially no monoazo compound constituting the ligand thereof, toner containing the charge control agent, and process for manufacturing a metal complex salt compound of Formula (I), which comprises a metallizing reaction for metallizing a monoazo compound of Formula (II) with iron, nickel, aluminum, titanium or zirconium to produce a metal complex salt compound, in which metallizing reaction a monohydric or dihydric alcohol is used as a reaction-promoting solvent: R: alkyl (C4 to 12); Y: halogen or alkyl (C 1 to 5); p and q: number of monoazo compounds coordinated to the metal M; p: 1, 2, 3 or 4; q: 0, 1, 2 or 3; p+q: 1 to 6; L1 and L2 is —O—; one of L3 and L4 is —O—, while the other is an —OH group or an —O− ion; M is iron, nickel, aluminum, titanium or zirconium; (Mx+)m: m number of metals of atomic valence x; m: 1 to 4; x: 2 or more; Z−: the negative charge in the parentheses; (A+)n is a hydrogen ion or an alkali metal ion, n=Z;
摘要翻译：包含基本上不含构成其配体的单偶氮化合物的式（I）的金属络盐化合物，含有电荷控制剂的调色剂和式（I）的金属络盐化合物的制备方法的电荷控制剂，其包含金属化将式（II）的单偶氮化合物与铁，镍，铝，钛或锆进行金属化反应以制备金属络盐化合物，其中使用一元或二元醇的金属化反应作为反应促进溶剂：R：烷基（C4至12）; Y：卤素或烷基（C 1〜5）; p和q：与金属M配位的单偶氮化合物的数量; p：1,2,3或4; q：0,1,2或3; p + q：1〜6; L1和L2是-O-; L3和L4之一是-O-，而另一个是-OH基或-O - 离子; M是铁，镍，铝，钛或锆; （M x +）m：m原子价金属数x; m：1〜4; x：2以上; Z-：括号中的负电荷; （A +）n是氢离子或碱金属离子，n = Z;

5. 发明授权

US4855208A Toner for developing electrostatic latent images 失效
标题翻译：用于显影静电潜像的调色剂
公开(公告)号：US4855208A
公开(公告)日：1989-08-08
申请号：US206472
申请日：1988-06-13
申请人： Akihiro Tada , Takashi Kiriu , Motoomi Arakawa
发明人： Akihiro Tada , Takashi Kiriu , Motoomi Arakawa
IPC分类号： G03G9/097
CPC分类号： G03G9/09783
摘要： A toner for developing electrostatic latent images which is characterized in that the toner comprises an aluminum compound of aromatic o-aminocarboxylic acid, the aromatic o-aminocarboxylic acid being represented by the formula ##STR1## wherein Q is benzene nucleus which is optionally substituted with at least one nuclear substituent or naphthalene nucleus which is optionally substituted with at least one nuclear substituent, R is hydrogen, alkyl (C.sub.1 -C.sub.18), aryl or nuclear substituted aryl (C.sub.6 -C.sub.18), aralkyl or nuclear substituted aralkyl (C.sub.7 -C.sub.18), or --COR', wherein R' is alkyl(C.sub.1 -C.sub.8), aryl(C.sub.6 -C.sub.8), alkoxy (C.sub.1 -C.sub.8) or amino.

6. 发明授权

US07795300B2 External preparation for skin 有权
标题翻译：外用皮肤准备
公开(公告)号：US07795300B2
公开(公告)日：2010-09-14
申请号：US10580882
申请日：2004-12-14
申请人： Akihiro Tada , Akiko Kanamaru
发明人： Akihiro Tada , Akiko Kanamaru
IPC分类号： A01N43/16 , A61K31/35 , C07D311/00 , A61Q5/08 , A61Q19/02
CPC分类号： A61Q19/02 , A61K8/347 , A61K8/498 , A61K8/97
摘要： The present invention relates to an external preparation for skin comprising a compound, such as centaureidin(5,7-dihydroxy-3,6-dimethoxy-2-(5-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one); 5,7-dihydroxy-3,6,8-trimethoxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one; 3,5-diethoxy-6,7-dimethoxy-2-(5-ethoxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; and 5,6-dihydroxy-3,7-dimethoxy-2-(5-hydroxy-2,4-dimethoxyphenyl)-4H-1-benzopyran-4-one; and/or salt thereof and 4-n-butyl resorcinol and/or a salt thereof.The present invention provides an external preparation for skin having a function as a substantial lightening cosmetic that exerts whitening action of inhibiting excessive melanin production and keeping natural-looking whiteness.
摘要翻译：本发明涉及皮肤外用剂，其包含化合物，例如分隔线（5,7-二羟基-3,6-二甲氧基-2-（5-羟基-4-甲氧基苯基）-4H-1-苯并吡喃-4-酮一）; 5,7-二羟基-3,6,8-三甲氧基-2-（3,4,5-三羟基苯基）-4H-1-苯并吡喃-4-酮; 3,5-二乙氧基-6,7-二甲氧基-2-（5-乙氧基-4-甲氧基苯基）-4H-1-苯并吡喃-4-酮; 和5,6-二羟基-3,7-二甲氧基-2-（5-羟基-2,4-二甲氧基苯基）-4H-1-苯并吡喃-4-酮; 和/或其盐和4-正丁基间苯二酚和/或其盐。本发明提供了具有作为实质性减轻化妆品的功能的皮肤外用剂，其具有抑制过量的黑色素生成并保持自然的白度的增白作用。

7. 发明授权

US07141601B2 Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same 有权
标题翻译：用于黑素细胞的树枝状伸长抑制剂和含有其的外用皮肤制剂
公开(公告)号：US07141601B2
公开(公告)日：2006-11-28
申请号：US10536675
申请日：2003-11-28
申请人： Akihiro Tada , Akiko Kanamaru , Yuko Saeki
发明人： Akihiro Tada , Akiko Kanamaru , Yuko Saeki
IPC分类号： A01N43/16 , A61K31/35 , C07D311/04 , C07D311/74 , C07D311/76
CPC分类号： A61Q19/02 , A61K8/498 , A61K2800/70
摘要： The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, wherein R1, R2, and R3 each independently represent a C1-4 alkyl group or hydrogen atom, and a skin preparation for external use comprising the dendrite elongation inhibitor for melanocytes as an active ingredient.
摘要翻译：本发明涉及由以下通式（1）表示的化合物和/或其盐组成的黑素细胞的枝晶延长抑制剂，其中R 1，R 2， SUB＆gt;和R 3 3各自独立地表示C 1-4烷基或氢原子，以及外用皮肤制剂，其包含黑色素细胞的枝晶延长抑制剂作为有效成分。

8. 发明申请

US20050288361A1 Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same 有权
标题翻译：用于黑素细胞的树枝状伸长抑制剂和含有其的外用皮肤制剂
公开(公告)号：US20050288361A1
公开(公告)日：2005-12-29
申请号：US10536675
申请日：2003-11-28
申请人： Akihiro Tada , Akiko Kanamaru , Yuko Saeki
发明人： Akihiro Tada , Akiko Kanamaru , Yuko Saeki
IPC分类号： A61K8/49 , A61K31/352 , A61K31/353 , A61Q19/02
CPC分类号： A61Q19/02 , A61K8/498 , A61K2800/70
摘要： The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, wherein R1, R2, and R3 each independently represent a C1-4 alkyl group or hydrogen atom, and a skin preparation for external use comprising the dendrite elongation inhibitor for melanocytes as an active ingredient.
摘要翻译：本发明涉及由以下通式（1）表示的化合物和/或其盐组成的黑素细胞的枝晶延长抑制剂，其中R 1，R 2， SUB＆gt;和R 3 3各自独立地表示C 1-4烷基或氢原子，以及外用皮肤制剂，其包含黑色素细胞的枝晶延长抑制剂作为有效成分。

9. 发明申请

US20050208409A1 Charge control agent and toner for electrostatic image development containing the same 失效
标题翻译：充电控制剂和含有静电图像显影的调色剂
公开(公告)号：US20050208409A1
公开(公告)日：2005-09-22
申请号：US10507299
申请日：2003-03-18
申请人： Masashi Yasumatsu , Toshihiro Urakawa , Akihiro Tada
发明人： Masashi Yasumatsu , Toshihiro Urakawa , Akihiro Tada
IPC分类号： G03G9/09 , G03G9/08
CPC分类号： G03G9/091
摘要： A charge control agent comprises a monoazo metals-compound including a monoazo compound represented by the following formula [I]: and metals of a metallic element or a metalloid coordinating to the monoazo compound. A toner for developing an electrostatic image comprises: the charge control agent including the monoazo compound and metals of the metallic element or the metalloid coordinating to the monoazo compound, a resin for the toner and a colorant.
摘要翻译：电荷控制剂包括包含由下式[I]表示的单偶氮化合物的单偶氮金属化合物：与单偶氮化合物配位的金属元素或准金属的金属。用于显影静电图像的调色剂包括：包含单偶氮化合物的电荷控制剂和与单偶氮化合物配位的金属元素或准金属的金属，调色剂用树脂和着色剂。

10. 发明申请

US20100081162A1 METHOD OF EVALUATING ANTIWRINKLE SUBSTANCE AND METHOD OF ASSESSING THE SKIN 审中-公开
标题翻译：评估抗皱物质的方法和评估皮肤的方法
公开(公告)号：US20100081162A1
公开(公告)日：2010-04-01
申请号：US12529505
申请日：2008-02-18
申请人： Naoko Kida , Akihiro Tada
发明人： Naoko Kida , Akihiro Tada
IPC分类号： C12Q1/02 , C07D311/02
CPC分类号： G01N33/6881 , C12N15/113 , C12N2310/14 , G01N2333/70546 , G01N2800/20
摘要： It is intended to provide a method whereby the skin conditions (for example, loss in the skin elasticity, wrinkle formation possibility, insufficient tightness in dermal collagen fiber bundles, or the like) can be exactly and conveniently assessed. It is also intended to provide a method whereby the wrinkle-improvement effect of a test substance can be exactly and conveniently evaluated. The skin conditions are assessed by using the expression amount of an adhesion factor in skin cells as an indication. The wrinkle reducing effect of a test substance is evaluated by using the expression amount of an adhesion factor in skin cells in the presence of the test substance as an indication.
摘要翻译：旨在提供一种能够准确且方便地评价皮肤状况（例如，皮肤弹性的损失，皱纹形成可能性，真皮胶原纤维束的紧密度不足等）的方法。还旨在提供一种可以精确且方便地评价测试物质的皱纹改善效果的方法。通过使用皮肤细胞中粘附因子的表达量作为指标来评估皮肤状况。在试验物质的存在下，通过使用皮肤细胞中的粘附因子的表达量作为指标来评价被检物质的皱纹减少效果。

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