专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070293701A1 Process for Producing 2-Halogenobenzamide Compound 有权
标题翻译：生产2-卤代苯甲酰胺化合物的方法
公开(公告)号：US20070293701A1
公开(公告)日：2007-12-20
申请号：US10584221
申请日：2004-12-22
申请人： Noboru Abe , Hiroki Kodama , Akihiko Yoshiura
发明人： Noboru Abe , Hiroki Kodama , Akihiko Yoshiura
IPC分类号： C07C231/12
CPC分类号： C07C315/04 , C07C317/28
摘要： A novel process for producing a 2-halogenobenzamide compound useful as a raw material or active ingredient for medicines and agricultural chemicals. The process, which is for producing a 2-halogenobenzamide compound represented by the general formula (I): (wherein R1, R2, R3, R4, and R6 may be the same or different and each represents hydrogen or C1-6 alkyl; R5 represents C1-6 alkyl; k is 1 or 2; Y1, Y2, Y3, and Y4 may be the same or different and each represents hydrogen, halogeno, etc.; and X represents chlorine, bromine, or iodine), is characterized by reacting an benzamide compound with a halogenating agent in the presence of a palladium catalyst to obtain a substituted benzamide compound and then reacting the resultant substituted benzamide compound with an oxidizing agent after or without isolating the substituted benzamide compound.
摘要翻译：一种生产用作药物和农药的原料或活性成分的2-卤代苯甲酰胺化合物的新方法。用于制备由通式（I）表示的2-卤代苯甲酰胺化合物的方法：（其中R 1，R 2，R 2，R 3， R 4，R 4和R 6可以相同或不同，各自表示氢或C 1-6烷基; R 0-4 > 5表示C 1-6烷基; k是1或2; Y 1，Y 2，Y 2， 3和Y 4可以相同或不同，各自表示氢，卤素等; X表示氯，溴或碘），其特征在于使苯甲酰胺化合物在钯催化剂的存在下用卤化剂得到取代的苯甲酰胺化合物，然后在得到的取代的苯甲酰胺化合物分离后，使得到的取代的苯甲酰胺化合物与氧化剂反应。

2. 发明授权

US06717013B2 Perfluoroalkylated aniline compound and process for producing the same 有权
标题翻译：全氟烷基化苯胺化合物及其制备方法
公开(公告)号：US06717013B2
公开(公告)日：2004-04-06
申请号：US10437381
申请日：2003-05-14
申请人： Masanobu Onishi , Akihiko Yoshiura , Eiji Kohno , Kenji Tsubata
发明人： Masanobu Onishi , Akihiko Yoshiura , Eiji Kohno , Kenji Tsubata
IPC分类号： C07C21100
CPC分类号： C07C323/41 , C07C209/68 , C07C211/52 , C07C213/08 , C07C215/76 , C07C217/84 , C07C233/15 , C07C271/14 , C07C323/36 , C07D209/08
摘要： The present invention provides an aniline derivative represented by the formula (I) wherein R1 and R2 are each H, (C1-12)alkyl, (C3-8)cycloalkyl, hydroxy(C1-12)alkyl, hydroxycarbonyl (C1-12)alkyl, (C1-6)-alkoxycarbonyl(C1-6)alkyl, —COR8, wherein R8 is H, halo-(C1-12)alkyl, (C3-8)cycloalkyl or (substituted) phenyl, COOR9, wherein R9 is a halo(C1-6)alkyl group, (substituted) phenyl or (substituted) benzyl; R3, R4, R5, R6 and R7 are each H, halogen, OH, nitro, halo(C1-12)alkylthio, (substituted) amino-(C1-2)alkyl, (substituted) phenyl, (substituted) benzyl, amino, —N(R10)R11 wherein R10 and R11 are each H, alkyl, cycloalkyl, (substituted) phenyl, (substituted) benzyl, —COR8 or COOR9, or (C2-27)perfluoroalkyl, etc., and a process for producing the aniline derivative. According to the process of the present invention, perfluoroalkylaniline derivatives can be obtained by using various anilines as the substrate with a high position selectivity and high yield.
摘要翻译：本发明提供由式（I）表示的苯胺衍生物，其中R 1和R 2各自为H，（C 1-12）烷基，（C 3-8）环烷基，羟基（C 1-12）烷基，羟基羰基（C 1-12）烷基，（C 1-6） - 烷氧基羰基（C 1-6）烷基，-COR 8，其中R 8是H，卤代（C 1-12）烷基，（C 3-8）环烷基或（取代的）苯基，COOR 9，其中R 9是卤代（C 1-6）烷基，（取代的）苯基或（取代的）苄基; R 3，R 4，R 5，R 6和R 7各自为H，卤素，OH，硝基，卤代（C 1-12）烷硫基，（取代的）氨基 - （C1- 2）烷基，（取代的）苯基，（取代的）苄基，氨基，-N（R 10）R 11，其中R 10和R 11各自为H，烷基，环烷基，（取代的），（取代的）苄基，-COR 8或COOR 9或（C2-27）全氟烷基等，以及苯胺衍生物的制备方法。根据本发明的方法，可以通过以高位置选择性和高收率使用各种苯胺作为基材来获得全氟烷基苯胺衍生物。

3. 发明授权

US07763750B2 Process for producing 2-halogenobenzamide compound 有权
标题翻译： 2-卤代苯甲酰胺化合物的制备方法
公开(公告)号：US07763750B2
公开(公告)日：2010-07-27
申请号：US10584221
申请日：2004-12-22
申请人： Noboru Abe , Hiroki Kodama , Akihiko Yoshiura
发明人： Noboru Abe , Hiroki Kodama , Akihiko Yoshiura
IPC分类号： C07C315/02 , C07C315/04 , C07C317/28 , C07B61/00
CPC分类号： C07C315/04 , C07C317/28
摘要： A novel process for producing a 2-halogenobenzamide compound useful as a raw material or active ingredient for medicines and agricultural chemicals. The process, which is for producing a 2-halogenobenzamide compound represented by the general formula (I): (wherein R1, R2, R3, R4, and R6 may be the same or different and each represents hydrogen or C1-6 alkyl; R5 represents C1-6 alkyl; k is 1 or 2; Y1, Y2, Y3, and Y4 may be the same or different and each represents hydrogen, halogeno, etc.; and X represents chlorine, bromine, or iodine), is characterized by reacting an benzamide compound with a halogenating agent in the presence of a palladium catalyst to obtain a substituted benzamide compound and then reacting the resultant substituted benzamide compound with an oxidizing agent after or without isolating the substituted benzamide compound.
摘要翻译：一种生产用作药物和农药的原料或活性成分的2-卤代苯甲酰胺化合物的新方法。用于制备由通式（I）表示的2-卤代苯甲酰胺化合物的方法：其中R 1，R 2，R 3，R 4和R 6可以相同或不同，各自表示氢或C 1-6烷基; R 5 表示C 1-6烷基; k为1或2; Y 1，Y 2，Y 3和Y 4可以相同或不同，各自表示氢，卤素等; X表示氯，溴或碘）在钯催化剂的存在下使苯甲酰胺化合物与卤化剂反应，得到取代的苯甲酰胺化合物，然后在得到的取代苯甲酰胺化合物分离后，使得到的取代苯甲酰胺化合物与氧化剂反应。

4. 发明授权

US06600074B2 Perfluoroalkylated aniline compound and process for producing the same 有权
标题翻译：全氟烷基化苯胺化合物及其制备方法
公开(公告)号：US06600074B2
公开(公告)日：2003-07-29
申请号：US10206769
申请日：2002-07-29
申请人： Masanobu Onishi , Akihiko Yoshiura , Eiji Kohno , Kenji Tsubata
发明人： Masanobu Onishi , Akihiko Yoshiura , Eiji Kohno , Kenji Tsubata
IPC分类号： C07C21100
CPC分类号： C07C323/41 , C07C209/68 , C07C211/52 , C07C213/08 , C07C215/76 , C07C217/84 , C07C233/15 , C07C271/14 , C07C323/36 , C07D209/08
摘要： The present invention provides an aniline derivative represented by the formula (I) wherein R1 and R2 are each H, (C1-12)alkyl, (C3-8)cycloalkyl, hydroxy(C1-12)alkyl, hydroxycarbonyl (C1-12)alkyl, (C1-6)-alkoxycarbonyl(C1-6)alkyl, —COR8, wherein R8 is H, halo-(C1-12)alkyl, (C3-8)cycloalkyl or (substituted) phenyl, COOR9, wherein R9 is a halo(C1-6)alkyl group, (substituted) phenyl or (substituted) benzyl; R3, R4, R5, R6and R7 are each H, halogen, OH, nitro, halo(C1-12)alkylthio, (substituted)amino-(C1-2)alkyl, (substituted) phenyl, (substituted) benzyl, amino, —N(R10)R11 wherein R10 and R11 are each H, alkyl, cycloalkyl, (substituted) phenyl, (substituted) benzyl, —COR8 or COOR9, or (C2-27)perfluoroalkyl, etc., and a process for producing the aniline derivative. According to the process of the present invention, perfluoroalkylaniline derivatives can be obtained by using various anilines as the substrate with a high position selectivity and high yield.
摘要翻译：本发明提供由式（I）表示的苯胺衍生物，其中R1和R2各自为H，（C1-12）烷基，（C3-8）环烷基，羟基（C1-12）烷基，羟基羰基（C1-12）烷基，（C 1-6） - 烷氧基羰基（C 1-6）烷基，-COR 8，其中R 8为H，卤代（C 1-12）烷基，（C 3-8）环烷基或（取代）苯基，COOR 9，其中R 9为（C 1-6）烷基，（取代的）苯基或（取代的）苄基; R3，R4，R5，R6和R7各自为H，卤素，OH，硝基，卤代（C1-12）烷硫基，（取代的）氨基 - （C1-2）烷基，（取代的）苯基，（取代的） -N（R 10）R 11其中R 10和R 11各自为H，烷基，环烷基，（取代）苯基，（取代的）苄基，-COR 8或COOR 9或（C 2- 27）全氟烷基等，苯胺衍生物。根据本发明的方法，可以通过以高位置选择性和高收率使用各种苯胺作为基材来获得全氟烷基苯胺衍生物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式