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1. 发明授权

US08771207B2 Device and a system for use in a procedure for improving a sealing function of a sphincter and a method for improving the sealing function of a sphincter 有权
公开(公告)号：US08771207B2
公开(公告)日：2014-07-08
申请号：US12665448
申请日：2008-06-27
申请人： John O'Dea , Adrian McHugh , Patrick Griffin
发明人： John O'Dea , Adrian McHugh , Patrick Griffin
IPC分类号： A61B5/103 , A61M29/00
CPC分类号： A61B5/1076 , A61B5/205 , A61B5/227 , A61B5/6853
摘要： A system (1) and a device (3) is used in a fundoplication procedure in order to avoid over-tightening of the fundus of the stomach when the fundus is being wrapped around the esophagus (7) adjacent the lower oesophageal sphincter (5). The device (3) comprises a catheter (8) having a primary balloon (12) located at a distal end (9) thereof which is inflatable with a saline solution by a primary pump (26). A pair of spaced apart primary stimulating electrodes (32) on the catheter (8) within the primary balloon (12) receive a stimulating current signal from a constant current signal generator (40) under the control of a microprocessor (43), which reads voltage signals from spaced apart primary receiving electrodes (35) on the catheter (8) in the balloon (12). The microprocessor (43) determines the diameter of the primary balloon (12) at locations adjacent the primary receiving electrodes (35), and an image (47) of the inflated primary balloon (12) is displayed on a visual display screen (48) along with corresponding diameter values of the primary balloon (12). The primary balloon (12) is located in the sphincter (5) and inflated with the saline solution until the sphincter (5) has been dilated to a desired diameter, which is observed on the visual display screen (45). As the fundus of the stomach is being wrapped around the esophagus (7) adjacent the sphincter (5) the diameter of the primary balloon (12) is observed so that the fundus is not over-tightened. A secondary balloon (50) on the catheter (8) is independently inflatable for simulating a bolus of food in the esophagus (7) so that the dilating response of the sphincter (5) can be determined by observing the image (47) of the primary balloon (12) and the diameter values thereof on the visual display screen (45).

2. 发明授权

US08756806B2 Catheter and a method for producing a catheter 有权
标题翻译：导管及其制造方法
公开(公告)号：US08756806B2
公开(公告)日：2014-06-24
申请号：US12665450
申请日：2008-06-27
申请人： John O'Dea , Adrian McHugh , Patrick Griffin
发明人： John O'Dea , Adrian McHugh , Patrick Griffin
IPC分类号： H01R43/02
CPC分类号： A61M25/0013 , A61B5/0215 , A61B5/036 , A61B5/1076 , A61B5/6852 , A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/00898 , A61M25/1027 , A61M2025/1088 , A61N1/056 , Y10T29/49002 , Y10T29/49117 , Y10T29/49174 , Y10T29/49179 , Y10T156/10
摘要： A method for producing a catheter (100) having a plurality of axially spaced apart electrodes (5) towards a distal end (4) of the catheter (100) comprises forming the electrodes (5) from a single sheet (110) of electrically conductive foil material by forming spaced apart slots (111) in the sheet material to define a plurality of spaced apart electrically conductive elements (114) extending transversely between spaced apart elongated connecting portion (112,113). The electrically conductive elements (114) subsequently form the electrodes (5), and are retained spaced apart by the connecting portions (112,113) until bonded to the catheter (100). Electrically conductive wires (10) electrically coupled to the electrically conductive elements (114) extend through an elongated slot (105) into and along an axial communicating bore (9) to a proximal end (3) of the catheter (100). Two pieces of double-sided adhesive tape (118) bonded to the electrically conductive elements (114) in turn bond the electrically conductive elements (114) to the catheter (100). After entering the wires (10) into the axial communicating bore (9) the electrically conductive elements (114) with the double-sided tape (118) are wrapped around the catheter (100) and are severed from the connecting portions (112,113). Free ends (115) of the electrically conductive elements (114) abut each other to form the electrodes (5) as band electrodes.
摘要翻译：一种用于制造导管（100）的方法，该导管（100）具有朝向导管（100）的远端（4）的多个轴向间隔开的电极（5），包括从单个导电片（110）形成电极（5）通过在片材中形成间隔开的狭槽（111）以限定在间隔开的细长连接部分（112,113）之间横向延伸的多个间隔开的导电元件（114）。导电元件（114）随后形成电极（5），并且被连接部分（112,113）间隔开直到结合到导管（100）。电耦合到导电元件（114）的导电导线（10）延伸穿过并沿着轴向连通孔（9）的细长槽（105）延伸到导管（100）的近端（3）。接合到导电元件（114）的两片双面胶带（118）又将导电元件（114）结合到导管（100）。在将电线（10）进入轴向连通孔（9）之后，具有双面胶带（118）的导电元件（114）缠绕在导管（100）周围并且从连接部分（112,113）切断。导电元件（114）的自由端（115）彼此邻接以形成电极（5）作为带状电极。

3. 发明申请

US20100228202A1 CATHETER AND A METHOD FOR PRODUCING A CATHETER 有权
标题翻译：导管及其制造方法
公开(公告)号：US20100228202A1
公开(公告)日：2010-09-09
申请号：US12665450
申请日：2008-06-27
申请人： John O'Dea , Adrian McHugh , Patrick Griffin
发明人： John O'Dea , Adrian McHugh , Patrick Griffin
IPC分类号： A61M25/00 , B29C65/00 , B29C63/10
CPC分类号： A61M25/0013 , A61B5/0215 , A61B5/036 , A61B5/1076 , A61B5/6852 , A61B18/1492 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/00898 , A61M25/1027 , A61M2025/1088 , A61N1/056 , Y10T29/49002 , Y10T29/49117 , Y10T29/49174 , Y10T29/49179 , Y10T156/10
摘要： A method for producing a catheter (100) having a plurality of axially spaced apart electrodes (5) towards a distal end (4) of the catheter (100) comprises forming the electrodes (5) from a single sheet (110) of electrically conductive foil material by forming spaced apart slots (111) in the sheet material to define a plurality of spaced apart electrically conductive elements (114) extending transversely between spaced apart elongated connecting portion (112,113). The electrically conductive elements (114) subsequently form the electrodes (5), and are retained spaced apart by the connecting portions (112,113) until bonded to the catheter (100). Electrically conductive wires (10) electrically coupled to the electrically conductive elements (114) extend through an elongated slot (105) into and along an axial communicating bore (9) to a proximal end (3) of the catheter (100). Two pieces of double-sided adhesive tape (118) bonded to the electrically conductive elements (114) in turn bond the electrically conductive elements (114) to the catheter (100). After entering the wires (10) into the axial communicating bore (9) the electrically conductive elements (114) with the double-sided tape (118) are wrapped around the catheter (100) and are severed from the connecting portions (112,113). Free ends (115) of the electrically conductive elements (114) abut each other to form the electrodes (5) as band electrodes.
摘要翻译：一种用于制造导管（100）的方法，该导管（100）具有朝向导管（100）的远端（4）的多个轴向间隔开的电极（5），包括从单个导电片（110）形成电极（5）通过在片材中形成间隔开的狭槽（111）以限定在间隔开的细长连接部分（112,113）之间横向延伸的多个间隔开的导电元件（114）。导电元件（114）随后形成电极（5），并且被连接部分（112,113）间隔开直到结合到导管（100）。电耦合到导电元件（114）的导电导线（10）延伸穿过并沿着轴向连通孔（9）的细长槽（105）延伸到导管（100）的近端（3）。接合到导电元件（114）的两片双面胶带（118）又将导电元件（114）结合到导管（100）。在将电线（10）进入轴向连通孔（9）之后，具有双面胶带（118）的导电元件（114）缠绕在导管（100）周围并且从连接部分（112,113）切断。导电元件（114）的自由端（115）彼此邻接以形成电极（5）作为带状电极。

4. 发明申请

US20100094328A1 SYSTEM, DEVICE AND A METHOD FOR DILATING A STRICTURE IN A LUMEN AND FOR DETERMINING THE TRANSVERSE CROSS-SECTIONAL AREA OF A LUMEN OR CAVITY 审中-公开
标题翻译：系统，装置和一种用于在乳液中稀释一种条件并用于确定一个或多个空气的横断面的区域的方法
公开(公告)号：US20100094328A1
公开(公告)日：2010-04-15
申请号：US12444985
申请日：2008-06-27
申请人： John O'dea , Adrian Mchugh , Patrick Griffin
发明人： John O'dea , Adrian Mchugh , Patrick Griffin
IPC分类号： A61M29/02
CPC分类号： A61M25/10181 , A61B5/0538 , A61B5/1076 , A61B5/4233 , A61B5/6853 , A61M25/1002 , A61M25/1011 , A61M25/10187 , A61M29/02 , A61M2025/1059
摘要： A system (1) for dilating an occlusion (3) in an oesophagus (4) comprises a device (5) having a catheter (8) extending from a proximal end (9) to a distal end (10). An inflatable balloon (12) defining a hollow interior region (14) is located on the catheter (8) adjacent the distal end (10) thereof for dilating the occlusion (3). The balloon (12) is inflated with a saline solution by a pump (34) through an axial communicating bore (20) and radial communicating bores (21) in the catheter (8). A pair of stimulating electrodes (25) on the catheter (8) within the balloon (12) adjacent axially opposite ends (18,19) thereof receive stimulating voltage signals from a signal generator (43). Receiving electrodes (28) on the catheter (8) between the stimulating electrodes (25) produce resulting voltage signals in response to the stimulating current signal on the stimulating electrodes (25) which are indicative of the transverse cross-sectional area of the balloon (12) adjacent the receiving electrodes (28) when the balloon (12) is inflated with the saline solution. A microprocessor (35) determines the diameter of the balloon (12) at the receiving electrodes (28) from the resulting signals thereon, and displays a three-dimensional image (46) of the balloon (12) on a visual display screen (47) as well as the corresponding diameter values in windows (48) on the visual display screen (47). A surgeon observes an image of the balloon (12) which corresponds to an image of the occlusion (3) and adjacent portion of the oesophagus 4) during dilating of the occlusion (3).
摘要翻译：用于扩张食管（4）中的闭塞（3）的系统（1）包括具有从近端（9）延伸到远端（10）的导管（8）的装置（5）。限定中空内部区域（14）的可膨胀气囊（12）位于邻近其远端（10）的导管（8）上，用于扩张闭塞（3）。气囊（12）通过泵（34）通过轴向连通孔（20）和导管（8）中的径向连通孔（21）用盐水溶液充气。邻近轴向相对端（18,19）的球囊（12）内的导管（8）上的一对刺激电极（25）从信号发生器（43）接收刺激电压信号。在刺激电极（25）之间的导管（8）上的接收电极（28）响应于刺激电极（25）上的刺激电流信号而产生所产生的电压信号，其表示球囊的横截面积（ 12），当气囊（12）用盐水溶液充气时，邻近接收电极（28）。微处理器（35）从其上产生的信号确定接收电极（28）处的球囊（12）的直径，并将气球（12）的三维图像（46）显示在视觉显示屏（47）上）以及视觉显示屏幕（47）上的窗口（48）中的相应直径值。外科医生观察气囊（12）的图像，其对应于闭塞（3）扩张期间闭塞（3）和食道4）的相邻部分的图像。

5. 发明申请

US20120035642A1 CATHETER, A BALLOON CATHETER AND A METHOD AND APPARATUS FOR MONITORING THE TRANSVERSE CROSS-SECTION OF A STOMA 有权
标题翻译：导管，气囊导管以及用于监测STOMA横断面部分的方法和装置
公开(公告)号：US20120035642A1
公开(公告)日：2012-02-09
申请号：US13255195
申请日：2010-03-09
申请人： John O'dea , Adrian McHugh , Eoin Bambury
发明人： John O'dea , Adrian McHugh , Eoin Bambury
IPC分类号： A61M29/00
CPC分类号： A61B5/1076 , A61B5/42 , A61B5/4238 , A61B5/6853 , A61F5/0063 , A61F2005/002 , A61M25/10 , A61M25/1002 , A61M25/1018 , A61M25/10184 , A61M25/10187 , A61M2025/0002 , A61M2025/1086 , A61M2025/1088 , A61M2025/1093 , A61M2210/1064
摘要： A balloon catheter (1) comprises a catheter (2) and a balloon (6) located on the distal end of the catheter. A pair of stimulating electrodes (15) for receiving a constant current stimulating signal when the balloon (6) is inflated with an electrically conductive medium and a plurality of sensing electrodes (16) for producing voltage response signals are located on the catheter (2). The voltage response signals are indicative of the values of the transverse cross-sectional area of the balloon (6) adjacent the sensing electrodes (16). A first lumen
摘要翻译：气囊导管（1）包括导管（2）和位于导管远端的球囊（6）。一对刺激电极（15）位于导管（2）上，用于在气球（6）用导电介质充气时接收恒流刺激信号，并且多个感测电极（16）用于产生电压响应信号，。电压响应信号表示与感测电极（16）相邻的球囊（6）的横截面积的值。第一腔<9）容纳充气介质往上和离开球囊（6），第二腔（19）容纳导电线（18）到刺激和感测电极（15,16）。压力传感器（21）位于第二内腔（19）中的保护壳体（22）中，并且通过保护壳体（22）中的连通开口（26）并且通过连通口（24）连通导管（2），其具有球囊（6）的中空内部区域（7）。

6. 发明授权

US09320868B2 Catheter and a method for manufacturing a catheter 有权
标题翻译：导管及其制造方法
公开(公告)号：US09320868B2
公开(公告)日：2016-04-26
申请号：US13637056
申请日：2011-03-28
申请人： Adrian McHugh
发明人： Adrian McHugh
IPC分类号： A61M25/16 , A61M25/00 , A61B18/14 , A61M25/10 , H05B3/10 , H05K1/02 , A61B18/08 , A61B18/00
CPC分类号： A61M25/0009 , A61B18/08 , A61B18/1492 , A61B2018/00214 , A61M25/0043 , A61M25/0068 , A61M25/0082 , A61M25/10 , A61M2025/0096 , H05B3/10 , H05K1/028 , Y10T29/49155
摘要： A balloon catheter comprising a catheter (3) and a balloon (7) located at a distal end (5) of the catheter (3). A plurality of measuring electrodes (12) formed on a primary substrate (17) extend around the catheter (3) within the balloon (7). The primary substrate (17) is formed by a portion of a flexible resilient membrane (25) which also forms a secondary substrate (19). The measuring electrodes (12) are formed on the primary substrate (17) by first electrically conductive tracks (27) and second electrically conductive tracks (28) which are electrically connected to the first electrically conductive tracks (27) are simultaneously formed on the secondary substrate (19). The membrane (25) is coiled to form a roll, and the primary substrate (17) is also coiled around the rolled secondary substrate (19). The coiled primary and secondary substrates (17,19) is urged through a second lumen (20) in the catheter (3) from the proximal end (4) thereof to a radial slot (21) in the catheter communicating with the second lumen (20). The primary substrate (17) is urged through the radial slot (20) and wrapped around and bonded to the catheter (3) to form the measuring electrodes (12) as band electrodes.
摘要翻译：一种气囊导管，其包括导管（3）和位于导管（3）的远端（5）处的球囊（7）。形成在主要基底（17）上的多个测量电极（12）围绕气囊（7）内的导管（3）延伸。主衬底（17）由也形成二次衬底（19）的柔性弹性膜（25）的一部分形成。测量电极（12）通过第一导电轨道（27）形成在主基底（17）上，并且电连接到第一导电轨道（27）的第二导电轨道（28）同时形成在次级基板（19）。卷（25）卷绕形成卷，并且主基板（17）也卷绕在轧制的二次基板（19）周围。卷绕的初级和次级衬底（17,19）被推动通过导管（3）中的第二内腔（20）从其近端（4）延伸到与第二管腔连通的导管中的径向槽（21） 20）。主衬底（17）被推动通过径向槽（20）并缠绕并结合到导管（3）上以形成测量电极（12）作为带状电极。

7. 发明授权

US09131898B2 Catheter, a balloon catheter and a method and apparatus for monitoring the transverse cross-section of a stoma 有权
标题翻译：导管，气囊导管以及用于监测造口横截面的方法和装置
公开(公告)号：US09131898B2
公开(公告)日：2015-09-15
申请号：US13255195
申请日：2010-03-09
申请人： John O'Dea , Adrian McHugh , Eoin Bambury
发明人： John O'Dea , Adrian McHugh , Eoin Bambury
IPC分类号： A61M29/00 , A61B5/00 , A61B5/107 , A61M25/10 , A61M25/00
CPC分类号： A61B5/1076 , A61B5/42 , A61B5/4238 , A61B5/6853 , A61F5/0063 , A61F2005/002 , A61M25/10 , A61M25/1002 , A61M25/1018 , A61M25/10184 , A61M25/10187 , A61M2025/0002 , A61M2025/1086 , A61M2025/1088 , A61M2025/1093 , A61M2210/1064
摘要： A balloon catheter comprises a catheter and a balloon located on the distal end of the catheter. A pair of stimulating electrodes for receiving a constant current stimulating signal when the balloon is inflated with an electrically conductive medium and a plurality of sensing electrodes for producing voltage response signals are located on the catheter. The voltage response signals are indicative of the values of the transverse cross-sectional area of the balloon adjacent the sensing electrodes. A first lumen accommodates the inflating medium to and from the balloon, and a second lumen accommodates electrically conductive wires to the stimulating and sensing electrodes. A pressure sensing element is located in a protective housing in the second lumen, and communicates through a communicating opening in the protective housing and through a communicating port in the catheter with a hollow interior region of the balloon. The balloon catheter may also be provided with a guide wire engaging element for engaging a guide wire externally of the balloon catheter.
摘要翻译：气囊导管包括位于导管远端的导管和气囊。一对刺激电极，用于当气囊用导电介质充气时接收恒流刺激信号，并且多个用于产生电压响应信号的感测电极位于导管上。电压响应信号表示与感测电极相邻的球囊的横截面积的值。第一内腔容纳充气介质往返气囊，第二腔容纳导电线到刺激和感测电极。压力感测元件位于第二内腔中的保护壳体中，并且通过保护壳体中的连通开口并且通过导管中的连通口与气囊的中空内部区域连通。气囊导管还可以设置有用于接合球囊导管外部的导丝的导丝接合元件。

8. 发明申请

US20130090599A1 CATHETER AND A METHOD FOR MANUFACTURING A CATHETER 有权
标题翻译：导管和制造导管的方法
公开(公告)号：US20130090599A1
公开(公告)日：2013-04-11
申请号：US13637056
申请日：2011-03-28
申请人： Adrian Mchugh
发明人： Adrian Mchugh
IPC分类号： A61M25/00 , H05B3/10 , H05K1/02 , A61M25/10
CPC分类号： A61M25/0009 , A61B18/08 , A61B18/1492 , A61B2018/00214 , A61M25/0043 , A61M25/0068 , A61M25/0082 , A61M25/10 , A61M2025/0096 , H05B3/10 , H05K1/028 , Y10T29/49155
摘要： A balloon catheter comprising a catheter (3) and a balloon (7) located at a distal end (5) of the catheter (3). A plurality of measuring electrodes (12) formed on a primary substrate (17) extend around the catheter (3) within the balloon (7). The primary substrate (17) is formed by a portion of a flexible resilient membrane (25) which also forms a secondary substrate (19). The measuring electrodes (12) are formed on the primary substrate (17) by first electrically conductive tracks (27) and second electrically conductive tracks (28) which are electrically connected to the first electrically conductive tracks (27) are simultaneously formed on the secondary substrate (19). The membrane (25) is coiled to form a roll, and the primary substrate (17) is also coiled around the rolled secondary substrate (19). The coiled primary and secondary substrates (17,19) is urged through a second lumen (20) in the catheter (3) from the proximal end (4) thereof to a radial slot (21) in the catheter communicating with the second lumen (20). The primary substrate (17) is urged through the radial slot (20) and wrapped around and bonded to the catheter (3) to form the measuring electrodes (12) as band electrodes.
摘要翻译：一种气囊导管，其包括导管（3）和位于导管（3）的远端（5）处的球囊（7）。形成在主要基底（17）上的多个测量电极（12）围绕气囊（7）内的导管（3）延伸。主衬底（17）由也形成二次衬底（19）的柔性弹性膜（25）的一部分形成。测量电极（12）通过第一导电轨道（27）形成在主基底（17）上，并且电连接到第一导电轨道（27）的第二导电轨道（28）同时形成在次级基板（19）。卷（25）卷绕形成卷，并且主基板（17）也卷绕在轧制的二次基板（19）周围。卷绕的初级和次级衬底（17,19）被推动通过导管（3）中的第二内腔（20）从其近端（4）延伸到与第二管腔连通的导管中的径向槽（21） 20）。主衬底（17）被推动通过径向槽（20）并缠绕并结合到导管（3）上以形成测量电极（12）作为带状电极。

9. 发明申请

US20100228192A1 DEVICE AND A SYSTEM FOR USE IN A PROCEDURE FOR IMPROVING A SEALING FUNCTION OF A SPHINCTER AND A METHOD FOR IMPROVING THE SEALING FUNCTION OF A SPHINCTER 有权
公开(公告)号：US20100228192A1
公开(公告)日：2010-09-09
申请号：US12665448
申请日：2008-06-27
申请人： John O'Dea , Adrian Mchugh , Patrick Griffin
发明人： John O'Dea , Adrian Mchugh , Patrick Griffin
IPC分类号： A61M29/00
CPC分类号： A61B5/1076 , A61B5/205 , A61B5/227 , A61B5/6853
摘要： A system (1) and a device (3) is used in a fundoplication procedure in order to avoid over-tightening of the fundus of the stomach when the fundus is being wrapped around the oesophagus (7) adjacent the lower oesophageal sphincter (5). The device (3) comprises a catheter (8) having a primary balloon (12) located at a distal end (9) thereof which is inflatable with a saline solution by a primary pump (26). A pair of spaced apart primary stimulating electrodes (32) on the catheter (8) within the primary balloon (12) receive a stimulating current signal from a constant current signal generator (40) under the control of a microprocessor (43), which reads voltage signals from spaced apart primary receiving electrodes (35) on the catheter (8) in the balloon (12). The microprocessor (43) determines the diameter of the primary balloon (12) at locations adjacent the primary receiving electrodes (35), and an image (47) of the inflated primary balloon (12) is displayed on a visual display screen (48) along with corresponding diameter values of the primary balloon (12). The primary balloon (12) is located in the sphincter (5) and inflated with the saline solution until the sphincter (5) has been dilated to a desired diameter, which is observed on the visual display screen (45). As the fundus of the stomach is being wrapped around the oesophagus (7) adjacent the sphincter (5) the diameter of the primary balloon (12) is observed so that the fundus is not over-tightened. A secondary balloon (50) on the catheter (8) is independently inflatable for simulating a bolus of food in the oesophagus (7) so that the dilating response of the sphincter (5) can be determined by observing the image (47) of the primary balloon (12) and the diameter values thereof on the visual display screen (45).

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