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1. 发明授权

US6080734A Liponucleotides of seco-nucleosides, their production as well as their use as antiviral pharmaceutical agents 失效
标题翻译：仲核苷的脂质体，其生产以及它们作为抗病毒药剂的用途
公开(公告)号：US6080734A
公开(公告)日：2000-06-27
申请号：US209484
申请日：1998-12-11
申请人： Harald Zilch , Dieter Herrmann
发明人： Harald Zilch , Dieter Herrmann
IPC分类号： C07F9/6561 , A61K31/675
CPC分类号： C07F9/65616
摘要： The present invention is directed to new phospholipid derivatives of acyclovir and ganciclovir that link a lipid moiety, which represents a substituted C3 backbone, to acyclovir or ganciclovir via phosphate or thiophosphate. The compounds are particularly suitable for the therapy of viral infections.
摘要翻译：本发明涉及通过磷酸盐或硫代磷酸酯将代表取代的C3骨架的脂质部分与阿昔洛韦或更昔洛韦连接的阿昔洛韦和更昔洛韦的新型磷脂衍生物。该化合物特别适用于病毒感染的治疗。

2. 发明授权

US07122302B2 Method for determining early HCV seroconversion 失效
公开(公告)号：US07122302B2
公开(公告)日：2006-10-17
申请号：US09896032
申请日：2001-06-29
申请人： Christoph Seidel , Ursula-Henrike Wienhues , Urban Schmitt , Manfred Motz , Michael Wiedmann , Barbara Upmeier , Erwin Soutschek
发明人： Christoph Seidel , Ursula-Henrike Wienhues , Urban Schmitt , Manfred Motz , Michael Wiedmann , Barbara Upmeier , Erwin Soutschek
IPC分类号： C12Q1/70
CPC分类号： C07K14/005 , A61K38/00 , C12N2770/24222 , G01N33/56983 , G01N33/5767 , Y10S436/82
摘要： The present invention concerns a polypeptide which is composed of the amino acids 1207±10 to 1488±10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.

3. 发明授权

US6036919A Diagnostic test carrier with multilayer field 失效
标题翻译：诊断测试载体与多层场
公开(公告)号：US6036919A
公开(公告)日：2000-03-14
申请号：US897513
申请日：1997-07-21
申请人： Detlef Thym , Wofgang-Reinhold Knappe , Rudolf Pachl , Hartmut Merdes , Robert Lorenz
发明人： Detlef Thym , Wofgang-Reinhold Knappe , Rudolf Pachl , Hartmut Merdes , Robert Lorenz
IPC分类号： G01N33/52 , G01N33/49
CPC分类号： G01N33/525 , Y10T436/25125
摘要： The present invention concerns a diagnostic test carrier for the determination of an analyte from whole blood with the aid of a reagent system contained in the carrier which includes a colour forming reagent with a test field which has a sample application side onto which the blood sample is applied and a detection side on which an optically detectable change takes place as a result of the reaction of analyte with the reagent system and which is constructed in such a way that erythrocytes present in the sample do not reach the detection side, which is characterized in that the test field comprises a transparent foil onto which a first and a second film layer are applied on top of one another and wherein the first layer located on the transparent foil scatters light considerably less in a wet state than the overlying second layer and wherein the side of the foil on which the first layer is applied which is opposite to the foil side is the detection side and the side of the second layer which is opposite to the side with which the second layer rests on the first is the sample application side. In addition the invention concerns a method for the determination of an analyte from whole blood with the aid of a diagnostic test carrier according to the invention.
摘要翻译：本发明涉及一种诊断测试载体，用于借助于载体中包含的试剂系统来确定全血中的分析物，所述试剂系统包括具有测试场的成色剂，所述测试场具有样品施用侧，血液样品应用和检测侧，由于分析物与试剂系统的反应而发生光学上可检测的变化，并且以使样品中存在的红细胞未到达检测侧的方式构建，其特征在于测试场包括透明箔，第一和第二膜层在其上彼此施加在其上，并且其中位于透明箔上的第一层在湿润状态下比上覆的第二层散射光更少，并且其中其上施加有与箔侧相对的第一层的箔的侧面是检测侧和第二层的侧面其与第一层位于第一层的一侧相反的是样品施加侧。此外，本发明涉及一种借助于根据本发明的诊断测试载体来确定来自全血的分析物的方法。

4. 发明申请

US20050281714A1 System for processing samples in a multichamber arrangement 失效
公开(公告)号：US20050281714A1
公开(公告)日：2005-12-22
申请号：US11189201
申请日：2005-07-25
申请人： Frank Schubert , Udo Eichenlaub , Armin Tgetgel
发明人： Frank Schubert , Udo Eichenlaub , Armin Tgetgel
IPC分类号： G01N35/10 , B01J3/02 , B01J4/00 , B01L3/00 , G01N35/00
CPC分类号： B01L3/5085 , G01N35/1065 , G01N2035/00277 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： System for processing samples, in particular samples containing nucleic acids comprising a multichamber arrangement the chambers of which are used to receive liquids and it also concerns a pipetting device for removing liquids from the chambers and/or dispensing liquid into the chambers, wherein the system has a contamination protection which can move relative to the multichamber arrangement and which prevents contamination of an adjacent second chamber with liquid from the first chamber during a pipetting operation in the first chamber, by preventing discharge of fluid droplets from the first chamber into the second chamber by at least partially covering the first chamber.

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